1-20 of 27
Hiroshi Shiku
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Abstract CT212: Adoptive transfer of wild-type TCR gene transduced T lymphocytes targeting MAGE-A4 antigen to patients with refractory esophageal cancer

Shinichi Kageyama, Hiroaki Ikeda, Naoko Imai, Mikiya Ishihara, Yoshihiro Miyahara, Shugo Ueda, Takeshi Ishikawa, Hiroaki Naota, Kohshi Ohishi, Taizo Shiraishi, Naoki Inoue, Masashige Tanabe, Tomohide Kidokoro, Hirofumi Yoshioka, Daisuke Tomura, Ikuei Nukaya, Junichi Mineno, Kazutoh Takesako, Naoyuki Katayama, Hiroshi Shiku
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): CT212.
https://doi.org/10.1158/1538-7445.AM2014-CT212
Published: 01 October 2014
View articletitled, Abstract CT212: Adoptive transfer of wild-type TCR gene transduced T lymphocytes targeting MAGE-A4 antigen to patients with refractory esophageal cancer
Journal Articles

Abstract B11: Control of in vivo spatiotemporal dynamics of antigen and adjuvant by a delivery system CHP nanogel markedly improves the immunogenicity and antitumor efficacy of long peptide cancer vaccine.

Daisuke Muraoka, Naozumi Harada, Tae Hayashi, Shin-ichi Sawada, Kazunari Akiyoshi, Hiroshi Shiku
Journal: Cancer Research
Cancer Res (2013) 73 (1_Supplement): B11.
https://doi.org/10.1158/1538-7445.TUMIMM2012-B11
Published: 02 April 2014
View articletitled, Abstract B11: Control of in vivo spatiotemporal dynamics of antigen and adjuvant by a delivery system CHP nanogel markedly improves the immunogenicity and antitumor efficacy of long peptide cancer vaccine.
Journal Articles

Intracellular Tumor-Associated Antigens Represent Effective Targets for Passive Immunotherapy

Takuro Noguchi, Takuma Kato, Linan Wang, Yuka Maeda, Hiroaki Ikeda, Eiichi Sato, Alexander Knuth, Sacha Gnjatic, Gerd Ritter, Shimon Sakaguchi, Lloyd J. Old, Hiroshi Shiku, Hiroyoshi Nishikawa
Journal: Cancer Research
Cancer Res (2012) 72 (7): 1672–1682.
https://doi.org/10.1158/0008-5472.CAN-11-3072
Published: 01 April 2012
View articletitled, Intracellular Tumor-Associated Antigens Represent Effective Targets for Passive Immunotherapy
Open the PDF for Intracellular Tumor-Associated Antigens Represent Effective Targets for Passive Immunotherapy in another window
Includes: Supplementary data
Journal Articles

Abstract 2408: Selective delivery of NY-ESO-1 antigen protein by cholesteryl pullulan (CHP) to CD8α+ dendritic cells in the draining lymph node for cross-presentation

Naozumi Harada, Daisuke Muraoka, Kazuo Tajima, Hiroshi Shiku
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2408.
https://doi.org/10.1158/1538-7445.AM10-2408
Published: 15 April 2010
View articletitled, Abstract 2408: Selective delivery of NY-ESO-1 antigen protein by cholesteryl pullulan (CHP) to CD8α+ dendritic cells in the draining lymph node for cross-presentation
Journal Articles

Abstract 5615: Effects of corticosteroids on tumor immunity induced by anti-CTLA-4 mAb therapy in a mouse model

Yuka Maeda, Takuma Kato, Linan Wang, Daisuke Muraoka, Eiichi Sato, Jedd D. Wolchok, Lloyd J. Old, Hiroshi Shiku, Hiroyoshi Nishikawa
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5615.
https://doi.org/10.1158/1538-7445.AM10-5615
Published: 15 April 2010
View articletitled, Abstract 5615: Effects of corticosteroids on tumor immunity induced by anti-CTLA-4 mAb therapy in a mouse model
Journal Articles

Abstract 2441: An innovative treatment modality of antibody therapy against intracellular tumor antigens

Takuro Noguchi, Takuma Kato, Daisuke Muraoka, Hiroaki Ikeda, Satoshi Kondo, Gerd Ritter, Lloyd J. Old, Hiroshi Shiku, Hiroyoshi Nishikawa
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2441.
https://doi.org/10.1158/1538-7445.AM10-2441
Published: 15 April 2010
View articletitled, Abstract 2441: An innovative treatment modality of antibody therapy against intracellular tumor antigens
Journal Articles

Abstract 4751: Peptide vaccine induces apoptosis of antigen-specific CD8+ T cells

Muraoka Daisuke, Hiroyoshi Nishikawa, Takuma Kato, Linan Wang, Yuka Maeda, Naozumi Harada, Takuro Noguchi, Yutaka Kawakami, Hiroshi Shiku
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4751.
https://doi.org/10.1158/1538-7445.AM10-4751
Published: 15 April 2010
View articletitled, Abstract 4751: Peptide vaccine induces apoptosis of antigen-specific CD8+ T cells
Journal Articles

Abstract 5325: Inhibition of CD4+CD25+ regulatory T cell suppression to anti-tumor responses by OK-432 (lyophilized Streptococcus pyogenes)

Michiko Hirayama, Hiroyoshi Nishikawa, Yasuhiro Nagata, Takemasa Tsuji, Sahoko Hori, Masatoshi Aoki, Shugo Ueda, Hideaki Tahara, Shinichi Kageyama, Lloyd J. Old, Hiroshi Shiku, Sacha Gnjatic
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5325.
https://doi.org/10.1158/1538-7445.AM10-5325
Published: 15 April 2010
View articletitled, Abstract 5325: Inhibition of CD4+CD25+ regulatory T cell suppression to anti-tumor responses by OK-432 (lyophilized Streptococcus pyogenes)
Journal Articles

Improved Expression and Reactivity of Transduced Tumor-Specific TCRs in Human Lymphocytes by Specific Silencing of Endogenous TCR

Sachiko Okamoto, Junichi Mineno, Hiroaki Ikeda, Hiroshi Fujiwara, Masaki Yasukawa, Hiroshi Shiku, Ikunoshin Kato
Journal: Cancer Research
Cancer Res (2009) 69 (23): 9003–9011.
https://doi.org/10.1158/0008-5472.CAN-09-1450
Published: 30 November 2009
View articletitled, Improved Expression and Reactivity of Transduced Tumor-Specific TCRs in Human Lymphocytes by Specific Silencing of Endogenous TCR
Open the PDF for Improved Expression and Reactivity of Transduced Tumor-Specific TCRs in Human Lymphocytes by Specific Silencing of Endogenous TCR in another window
Includes: Supplementary data
Journal Articles

Regulatory T Cell–Resistant CD8+ T Cells Induced by Glucocorticoid-Induced Tumor Necrosis Factor Receptor Signaling

Hiroyoshi Nishikawa, Takuma Kato, Michiko Hirayama, Yuki Orito, Eiichi Sato, Naozumi Harada, Sacha Gnjatic, Lloyd J. Old, Hiroshi Shiku
Journal: Cancer Research
Cancer Res (2008) 68 (14): 5948–5954.
https://doi.org/10.1158/0008-5472.CAN-07-5839
Published: 15 July 2008
View articletitled, Regulatory T Cell–Resistant CD8+ T Cells Induced by Glucocorticoid-Induced Tumor Necrosis Factor Receptor Signaling
Open the PDF for Regulatory T Cell–Resistant CD8+ T Cells Induced by Glucocorticoid-Induced Tumor Necrosis Factor Receptor Signaling in another window
Includes: Supplementary data
Journal Articles

Functional analyses of T cells transduced with MAGE-A4-specific αβ type TCR genes

Michiko Hirayama, Atsunori Hiasa, Hiroyoshi Nishikawa, Yoshitaka Shirakura, Hiroaki Ikeda, Shigehisa Kitano, Kazuo Tajima, Ikuei Nukaya, Shen Sin Yu, Junichi Mineno, Mamoru Ito, Ikunoshin Kato, Hiroshi Shiku
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4628.
Published: 01 May 2008
View articletitled, Functional analyses of T cells transduced with MAGE-A4-specific αβ type TCR genes
Journal Articles

Combination cancer vaccine of CHP-NY-ESO-1 and CHP-HER2 with immuno-adjuvant, OK-432, for chemorefractory metastatic or recurrent esophageal cancer patients

Shugo Ueda, Masatoshi Aoki, Hiroyoshi Nishikawa, Michiko Hirayama, Shigehisa Kitano, Eriko Hayashi, Michiyuki Kanai, Arimichi Takabayashi, Hiroshi Shiku, Shinichi Kageyama
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2839.
Published: 01 May 2008
View articletitled, Combination cancer vaccine of CHP-NY-ESO-1 and CHP-HER2 with immuno-adjuvant, OK-432, for chemorefractory metastatic or recurrent esophageal cancer patients
Journal Articles

Rapid αβ τCR-mediated responses in γδ T cells transduced with cancer-specific TCR

Atsunori Hiasa, Hiroyoshi Nishikawa, Michiko Hirayama, Shigehisa Kitano, Eiichi Nakayama, Sachiko Okamoto, Hideto Chono, Seung Shin Yu, Junichi Mineno, Yoshimasa Tanaka, Nagahiro Minato, Ikunoshin Kato, Hiroshi Shiku
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4623.
Published: 01 May 2008
View articletitled, Rapid αβ τCR-mediated responses in γδ T cells transduced with cancer-specific TCR
Journal Articles

Humoral immune responses in patients vaccinated with HER2 protein complexed with a novel antigen delivery system of cholesteryl pullulan(CHP-HER2)

Shigehisa Kitano, Michiko Hirayama, Shinichi Kageyama, Yasuhiro Nagata, Masakatsu Nishikawa, Andrew M. Scott, Roger Murphy, Eric W. Hoffman, Lloyd J. Old, Hiroshi Shiku
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 152.
Published: 15 April 2006
View articletitled, Humoral immune responses in patients vaccinated with HER2 protein complexed with a novel antigen delivery system of cholesteryl pullulan(CHP-HER2)
Journal Articles

Cellular and humoral immune responses in patients vaccinated with HER2 protein combined with a novel nanoparticle antigen delivery system of cholesteryl hydrophobized polysacharide(CHP-HER2)

Shigehisa Kitano, Shinichi Kageyama, Yasuhiro Nagata, Yoshihiro Miyahara, Atsunori Hiasa, Hiroaki Naota, Satoshi Okumura, Hiroshi Imai, Taizou Shiraishi, Masahiro Masuya, Masakatsu Nishikawa, Andrew M. Scott, Roger Murphy, Eric W. Hoffman, Lloyd J. Old, Hiroshi Shiku
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1454.
Published: 01 May 2005
View articletitled, Cellular and humoral immune responses in patients vaccinated with HER2 protein combined with a novel nanoparticle antigen delivery system of cholesteryl hydrophobized polysacharide(CHP-HER2)
Journal Articles

Microarray Reveals Differences in Both Tumors and Vascular Specific Gene Expression in de Novo CD5+ and CD5− Diffuse Large B-Cell Lymphomas

Tohru Kobayashi, Motoko Yamaguchi, Seungchan Kim, Jun Morikawa, Shoko Ogawa, Satoshi Ueno, Edward Suh, Edward Dougherty, Ilya Shmulevich, Hiroshi Shiku, Wei Zhang
Journal: Cancer Research
Cancer Res (2003) 63 (1): 60–66.
Published: 01 January 2003
View articletitled, Microarray Reveals Differences in Both Tumors and Vascular Specific Gene Expression in de Novo CD5+ and CD5− Diffuse Large B-Cell Lymphomas
Open the PDF for Microarray Reveals Differences in Both Tumors and Vascular Specific Gene Expression in de Novo CD5+ and CD5− Diffuse Large B-Cell Lymphomas in another window
Journal Articles

A Novel Hydrophobized Polysaccharide/Oncoprotein Complex Vaccine Induces in Vitro and in Vivo Cellular and Humoral Immune Responses against HER2-expressing Murine Sarcomas

Xiao-Gang Gu, Michael Schmitt, Atsunori Hiasa, Yasuhiro Nagata, Hiroaki Ikeda, Yoshihiro Sasaki, Kazunari Akiyoshi, Junzo Sunamoto, Hideo Nakamura, Kagemasa Kuribayashi, Hiroshi Shiku
Journal: Cancer Research
Cancer Res (1998) 58 (15): 3385–3390.
Published: 01 August 1998
View articletitled, A Novel Hydrophobized Polysaccharide/Oncoprotein Complex Vaccine Induces in Vitro and in Vivo Cellular and Humoral Immune Responses against HER2-expressing Murine Sarcomas
Open the PDF for A Novel Hydrophobized Polysaccharide/Oncoprotein Complex Vaccine Induces in Vitro and in Vivo Cellular and Humoral Immune Responses against HER2-expressing Murine Sarcomas in another window
Journal Articles

High Expression of Ganglioside α-2,8-Sialyltransferase (GD3 Synthase) Gene in Adult T-Cell Leukemia Cells Unrelated to the Gene Expression of Human T-Lymphotropic Virus Type I

Masahiko Okada, Keiko Furukawa, Shuji Yamashiro, Yasuaki Yamada, Masashi Haraguchi, Keizo Horibe, Koji Kato, Yoshiro Tsuji, Hiroshi Shiku, Koichi Furukawa
Journal: Cancer Research
Cancer Res (1996) 56 (12): 2844–2848.
Published: 01 June 1996
View articletitled, High Expression of Ganglioside α-2,8-Sialyltransferase (GD3 Synthase) Gene in Adult T-Cell Leukemia Cells Unrelated to the Gene Expression of Human T-Lymphotropic Virus Type I
Open the PDF for High Expression of Ganglioside α-2,8-Sialyltransferase (GD3 Synthase) Gene in Adult T-Cell Leukemia Cells Unrelated to the Gene Expression of Human T-Lymphotropic Virus Type I in another window
Journal Articles

Gene Therapy for Hepatoma Cells Using a Retrovirus Vector Carrying Herpes Simplex Virus Thymidine Kinase Gene under the Control of Human α-Fetoprotein Gene Promoter

Akio Ido, Keisuke Nakata, Yuji Kato, Kazuhiko Nakao, Ken Murata, Masatoshi Fujita, Nobuko Ishii, Taiki Tamaoki, Hiroshi Shiku, Shigenobu Nagataki
Journal: Cancer Research
Cancer Res (1995) 55 (14): 3105–3109.
Published: 01 July 1995
View articletitled, Gene Therapy for Hepatoma Cells Using a Retrovirus Vector Carrying Herpes Simplex Virus Thymidine Kinase Gene under the Control of Human α-Fetoprotein Gene Promoter
Open the PDF for Gene Therapy for Hepatoma Cells Using a Retrovirus Vector Carrying Herpes Simplex Virus Thymidine Kinase Gene under the Control of Human α-Fetoprotein Gene Promoter in another window
Journal Articles

Two Isotypes of Murine nm23/Nucleoside Diphosphate Kinase, nm23-M1 and nm23-M2, Are Involved in Metastatic Suppression of a Murine Melanoma Line

Hideo Baba, Takeshi Urano, Kazuya Okada, Koichi Furukawa, Eiichi Nakayama, Hajime Tanaka, Katsuro Iwasaki, Hiroshi Shiku
Journal: Cancer Research
Cancer Res (1995) 55 (9): 1977–1981.
Published: 01 May 1995
View articletitled, Two Isotypes of Murine nm23/Nucleoside Diphosphate Kinase, nm23-M1 and nm23-M2, Are Involved in Metastatic Suppression of a Murine Melanoma Line
Open the PDF for Two Isotypes of Murine nm23/Nucleoside Diphosphate Kinase, nm23-M1 and nm23-M2, Are Involved in Metastatic Suppression of a Murine Melanoma Line in another window