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Hiroshi Okuda
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Journal Articles

Abstract C75: miR-7 suppresses brain metastasis of cancer stem-like cells by modulating Kruppel-like factor 4 in breast cancer

Fei Xing, Hiroshi Okuda, Aya Kobayashi, Puspa R. Pandey, Puspa R. Pandey, Sambad Sharma, Yin-Yuan Mo, Yin Liu, Kerui Wu, Kounosuke Watabe
Journal: Cancer Research
Cancer Res (2013) 73 (3_Supplement): C75.
https://doi.org/10.1158/1538-7445.TIM2013-C75
Published: 01 May 2014
View article titled, Abstract C75: miR-7 suppresses brain metastasis of cancer stem-like cells by modulating Kruppel-like factor 4 in breast cancer
Journal Articles

Abstract C92: Bone morphogenetic protein 7 regulates dormancy and recurrence of prostate cancer stem cell in bone

Aya Kobayashi, Fei Xing, Hiroshi Okuda, Puspa R. Pandey, Sudha Pai, Misako Watabe, Kounosuke Watabe
Journal: Cancer Research
Cancer Res (2013) 73 (3_Supplement): C92.
https://doi.org/10.1158/1538-7445.TIM2013-C92
Published: 01 May 2014
View article titled, Abstract C92: Bone morphogenetic protein 7 regulates dormancy and recurrence of prostate cancer stem cell in bone
Journal Articles

Abstract A13: Interleukin-1β promotes brain metastasis of breast cancer by activating Notch signaling through reactive astrocytes

Fei Xing, Aya Kobayashi, Hiroshi Okuda, Misako Watabe, Puspa R. Pandey, Sudha K. Pai, Yin Liu, Kerui Wu, Kounosuke Watabe
Journal: Cancer Research
Cancer Res (2013) 73 (3_Supplement): A13.
https://doi.org/10.1158/1538-7445.TIM2013-A13
Published: 01 May 2014
View article titled, Abstract A13: Interleukin-1β promotes brain metastasis of breast cancer by activating Notch signaling through reactive astrocytes
Journal Articles

Abstract 3084: miR509 suppresses brain metastasis of breast cancer cells by modulating RhoC and TNF alpha.

Fei Xing, Hiroshi Okuda, Aya Kobayashi, Puspa R. Pandey, Sambad Sharma, Yin-Yuan Mo, Yin Liu, Kerui Wu, Kounosuke Watabe
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3084.
https://doi.org/10.1158/1538-7445.AM2013-3084
Published: 15 April 2013
View article titled, Abstract 3084: miR509 suppresses brain metastasis of breast cancer cells by modulating RhoC and TNF alpha.
Journal Articles

Abstract 3865: HAS2 promotes tumor progression by stimulating interaction of cancer stem-like cells with tumor associated macrophage and stromal cells through a paracrine loop of growth factors in the bone.

Sambad Sharma, Hiroshi Okuda, Fei Xing, Aya Kobayashi, Misako Watabe, Puspa R. Pandey, Sudha K. Pai, Wen Liu, Koji Fukuda, Megumi Iiizumi, Kounosuke Watabe
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3865.
https://doi.org/10.1158/1538-7445.AM2013-3865
Published: 15 April 2013
View article titled, Abstract 3865: HAS2 promotes tumor progression by stimulating interaction of cancer stem-like cells with tumor associated macrophage and stromal cells through a paracrine loop of growth factors in the bone.
Journal Articles

Abstract 1416: BMP 7 regulates dormancy and recurrence of prostate cancer stem cell in bone via P38/NDRG1/P21 signaling axis.

Fei Xing, Aya Kobayashi, Hiroshi Okuda, Puspa Pandey, Misako Watabe, Sudha K. Pai, Sambad Sharma, Kounosuke Watabe
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1416.
https://doi.org/10.1158/1538-7445.AM2013-1416
Published: 15 April 2013
View article titled, Abstract 1416: BMP 7 regulates dormancy and recurrence of prostate cancer stem cell in bone via P38/NDRG1/P21 signaling axis.
Journal Articles

miR-7 Suppresses Brain Metastasis of Breast Cancer Stem-Like Cells By Modulating KLF4

Hiroshi Okuda, Fei Xing, Puspa R. Pandey, Sambad Sharma, Misako Watabe, Sudha K. Pai, Yin-Yuan Mo, Megumi Iiizumi-Gairani, Shigeru Hirota, Yin Liu, Kerui Wu, Radhika Pochampally, Kounosuke Watabe
Journal: Cancer Research
Cancer Res (2013) 73 (4): 1434–1444.
https://doi.org/10.1158/0008-5472.CAN-12-2037
Published: 14 February 2013
View article titled, miR-7 Suppresses Brain Metastasis of Breast Cancer Stem-Like Cells By Modulating KLF4
Open the PDF for miR-7 Suppresses Brain Metastasis of Breast Cancer Stem-Like Cells By Modulating KLF4 in another window
Journal Articles

Abstract 3323: Hyaluronan synthase 2 promotes breast cancer bone metastasis by stimulating interaction of cancer stem-like cells with tumor-associated macrophage

Hiroshi Okuda, Fei Xing, Aya Kobayashi, Misako Watabe, Sudha K. Pai, Wen Liu, Puspa R. Pandey, Koji Fukuda, Megumi Iiizumi
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3323.
https://doi.org/10.1158/1538-7445.AM2012-3323
Published: 15 April 2012
View article titled, Abstract 3323: Hyaluronan synthase 2 promotes breast cancer bone metastasis by stimulating interaction of cancer stem-like cells with tumor-associated macrophage
Journal Articles

Abstract 3419: N-myc downstream regulated gene 1, NDRG1, modulates Wnt-β-catenin signaling and pleiotropically suppresses metastasis

Wen Liu, Fei Xing, Megumi Iiizumi-Gairani, Hiroshi Okuda, Misako Watabe, Sudha K. Pai, Puspa R. Pandey, Shigeru Hirota, Aya Kobayashi, Koji Fukuda, Yi Li, Kounosuke Watabe
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3419.
https://doi.org/10.1158/1538-7445.AM2012-3419
Published: 15 April 2012
View article titled, Abstract 3419: N-myc downstream regulated gene 1, NDRG1, modulates Wnt-β-catenin signaling and pleiotropically suppresses metastasis
Journal Articles

Abstract 1531: Reactive astrocytes promote the growth of cancer stem-like cells of metastatic breast tumor by activating Notch signaling in brain

Fei Xing, Aya Kobayashi, Hiroshi Okuda, Misako Watabe, Puspa R. Pandey, Sudha K. Pai, Koji Fukuda, Megumi Iiizumi, Kounosuke Watabe
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1531.
https://doi.org/10.1158/1538-7445.AM2012-1531
Published: 15 April 2012
View article titled, Abstract 1531: Reactive astrocytes promote the growth of cancer stem-like cells of metastatic breast tumor by activating Notch signaling in brain
Journal Articles

Hyaluronan Synthase HAS2 Promotes Tumor Progression in Bone by Stimulating the Interaction of Breast Cancer Stem–Like Cells with Macrophages and Stromal Cells

Hiroshi Okuda, Aya Kobayashi, Bo Xia, Misako Watabe, Sudha K. Pai, Shigeru Hirota, Fei Xing, Wen Liu, Puspa R. Pandey, Koji Fukuda, Vishnu Modur, Arnab Ghosh, Andrew Wilber, Kounosuke Watabe
Journal: Cancer Research
Cancer Res (2012) 72 (2): 537–547.
https://doi.org/10.1158/0008-5472.CAN-11-1678
Published: 16 January 2012
View article titled, Hyaluronan Synthase HAS2 Promotes Tumor Progression in Bone by Stimulating the Interaction of Breast Cancer Stem–Like Cells with Macrophages and Stromal Cells
Open the PDF for Hyaluronan Synthase HAS2 Promotes Tumor Progression in Bone by Stimulating the Interaction of Breast Cancer Stem–Like Cells with Macrophages and Stromal Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 3409: Hyaluronan synthase 2 promotes tumor progression by stimulating interaction of cancer stem-like cells with tumor associated macrophage and stromal cells in the bone

Hiroshi Okuda, Aya Kobayashi, Misako Watabe, Sudha K. Pai, Wen Liu, Fei Xing, Puspa R. Pandey, Koji Fukuda, Megumi Iiizumi, Kounosuke Watabe
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3409.
https://doi.org/10.1158/1538-7445.AM2011-3409
Published: 15 April 2011
View article titled, Abstract 3409: Hyaluronan synthase 2 promotes tumor progression by stimulating interaction of cancer stem-like cells with tumor associated macrophage and stromal cells in the bone
Journal Articles

Abstract 1028: Hypoxia induces Notch signaling and promotes breast cancer metastasis by stimulating growth and self renewal of cancer stem-like cells

Fei Xing, Hiroshi Okuda, Misako Watabe, Aya Kobayashi, Sudha K. Pai, Wen Liu, Puspa R. Pandey, Koji Fukuda, Shigeru Hirota, Tamotsu Sugai, Go Wakabayashi, Keisuke Koeda, Masahiro Kashiwaba, Kazuyuki Suzuki, Toshimi Chiba, Masaki Endo, Kounosuke Watabe
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1028.
https://doi.org/10.1158/1538-7445.AM2011-1028
Published: 15 April 2011
View article titled, Abstract 1028: Hypoxia induces Notch signaling and promotes breast cancer metastasis by stimulating growth and self renewal of cancer stem-like cells
Journal Articles

Abstract 979: Upregulation of lipogenic genes, SREBP-1, ACLY, ACC-1 and FAS, confer proliferation and survival advantages to cancer stem-like cells in ductal carcinoma in situ

Puspa R. Pandey, Hiroshi Okuda, Watabe Misako, Sudha K. Pai, Wen Liu, Aya Kobayashi, Fei Xing, Koji Fukuda, Shigeru Hirota, Tamotsu Sugai, Go Wakabayashi, Keisuke Koeda, Masahiro Kashiwaba, Kazuyuki Suzuki, Toshimi Chiba, Masaki Endo, Tomoaki Fujioka, Susumu Tanji, Yin-Yuan Mo, Deliang Cao, Andrew C. Wilber, Kounosuke Watabe
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 979.
https://doi.org/10.1158/1538-7445.AM2011-979
Published: 15 April 2011
View article titled, Abstract 979: Upregulation of lipogenic genes, SREBP-1, ACLY, ACC-1 and FAS, confer proliferation and survival advantages to cancer stem-like cells in ductal carcinoma in situ
Journal Articles

Abstract 5762: Role of BMP7 in dormancy and recurrence of prostatic tumor stem cell in the bone metastasis

Aya Kobayashi, Hiroshi Okuda, Eiji Furuta, Puspa R. Pandey, Misako Watabe, Sudha K. Pai, Fei Xing, Wen Liu, Kounosuke Watabe
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5762.
https://doi.org/10.1158/1538-7445.AM10-5762
Published: 15 April 2010
View article titled, Abstract 5762: Role of BMP7 in dormancy and recurrence of prostatic tumor stem cell in the bone metastasis
Journal Articles

Abstract 1413: Interleukin-1β promotes brain metastasis of breast cancer by activating Notch signaling through reactive astrocytes

Fei Xing, Hiroshi Okuda, Eiji Furuta, Misako Watabe, Aya Kobayashi, Puspa R. Pandey, Sudha K. Pai, Wen Liu, Kounosuke Watabe
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1413.
https://doi.org/10.1158/1538-7445.AM10-1413
Published: 15 April 2010
View article titled, Abstract 1413: Interleukin-1β promotes brain metastasis of breast cancer by activating Notch signaling through reactive astrocytes
Journal Articles

Abstract #3064: The expression of metastasis suppressor gene, KAI1/CD82, is down-regulated by OCT4, SOX2 and NANOG in tumor stem cells of breast cancer

Hiroshi Okuda, Eiji Furuta, Misako Watabe, Sudha Pai, Wen Liu, Aya Kobayashi, Fei Xing, Puspa Pandey, Megumi Iiizumi, Kounosuke Watabe
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3064.
Published: 01 May 2009
View article titled, Abstract #3064: The expression of metastasis suppressor gene, KAI1/CD82, is down-regulated by OCT4, SOX2 and NANOG in tumor stem cells of breast cancer
Journal Articles

Abstract #275: Notch pathway is stimulated by hypoxia and promotes metastasis through activation of EMT and metalloproteinase

Fei Xing, Eiji Furuta, Misako Watabe, Wen Liu, Puspa Pandey, Hiroshi Okuda, Aya Kobayashi, Megumi Iiizumi, Kounosuke Watabe
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 275.
Published: 01 May 2009
View article titled, Abstract #275: Notch pathway is stimulated by hypoxia and promotes metastasis through activation of EMT and metalloproteinase
Journal Articles

Abstract #10: Resveratrol induces apoptosis by blocking enzymatic activity and destabilizing the protein of fatty acid synthase in breast tumor cells

Eiji Furuta, Puspa Pandey, Hiroshi Okuda, Misako Watabe, Sudha Pai, Megumi Iiizumi, Wen Liu, Fei Xing, Aya Kobayashi, Kounosuke Watabe
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 10.
Published: 01 May 2009
View article titled, Abstract #10: Resveratrol induces apoptosis by blocking enzymatic activity and destabilizing the protein of fatty acid synthase in breast tumor cells
Journal Articles

Abstract #2662: Inhibition of fatty acid synthase and induction of apoptosis in human breast cancer cells by Cacalia deliphiniifolia

Wen Liu, Eiji Furuta, Misako Watabe, Kazutoshi Shindo, Fei Xing, Sudha Pai, Hiroshi Okuda, Megumi Iiizumi, Puspa Pandey, Aya Kobayashi, Kounosuke Watabe
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2662.
Published: 01 May 2009
View article titled, Abstract #2662: Inhibition of fatty acid synthase and induction of apoptosis in human breast cancer cells by <em>Cacalia deliphiniifolia</em>