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Hiroshi Ikeda
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Journal Articles

Abstract 387: Targeted exome sequences of cancer-related genes in human cancers using amplicon sequencing

Yasushi Sasaki, Takafumi Nakagaki, Miyuki Tamura, Hisayo Fukushima, Hiroshi Ikeda, Ryota Koyama, Masashi Idogawa, Takashi Tokino
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 387.
https://doi.org/10.1158/1538-7445.AM2017-387
Published: 01 July 2017
View article titled, Abstract 387: Targeted exome sequences of cancer-related genes in human cancers using amplicon sequencing
Journal Articles

Abstract 3188: Targeted semiconductor sequencing of 409 cancer-related genes for somatic mutations and copy number variations in multiple myeloma

Hiroshi Ikeda, Yasushi Sasaki, Kazuya Ishiguro, Tadao Ishida, Yuka Aoki, Takashi Tokino
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3188.
https://doi.org/10.1158/1538-7445.AM2016-3188
Published: 15 July 2016
View article titled, Abstract 3188: Targeted semiconductor sequencing of 409 cancer-related genes for somatic mutations and copy number variations in multiple myeloma
Journal Articles

Abstract 4424: Molecular diagnostics of drug resistant multiple myeloma cases using targeted next generation sequencing

Hiroshi Ikeda, Yasushi Sasaki, Tetsuyuki Igarashi, Yuka Aoki, Toshiaki Hayashi, Tadao Ishida, Takashi Tokino, Yasuhisa Sinomura
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4424.
https://doi.org/10.1158/1538-7445.AM2015-4424
Published: 01 August 2015
View article titled, Abstract 4424: Molecular diagnostics of drug resistant multiple myeloma cases using targeted next generation sequencing
Journal Articles

Abstract 139: Interaction between monocytes and bone marrow microenvironment in pathogenesis of multiple myeloma

Hiroshi Ikeda, Yuka Aoki, Toshiaki Hyayashi, Yumiko Maruyama, Tadao Ishida, Takashi Tokino, Yasuhisa Shinomura, Yasushi Sasaki
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 139.
https://doi.org/10.1158/1538-7445.AM2014-139
Published: 01 October 2014
View article titled, Abstract 139: Interaction between monocytes and bone marrow microenvironment in pathogenesis of multiple myeloma
Journal Articles

GLI1 Interferes with the DNA Mismatch Repair System in Pancreatic Cancer through BHLHE41-Mediated Suppression of MLH1

Shingo Inaguma, Miho Riku, Mitsuyoshi Hashimoto, Hideki Murakami, Shinsuke Saga, Hiroshi Ikeda, Kenji Kasai
Journal: Cancer Research
Cancer Res (2013) 73 (24): 7313–7323.
https://doi.org/10.1158/0008-5472.CAN-13-2008
Published: 16 December 2013
View article titled, GLI1 Interferes with the DNA Mismatch Repair System in Pancreatic Cancer through BHLHE41-Mediated Suppression of MLH1
Open the PDF for GLI1 Interferes with the DNA Mismatch Repair System in Pancreatic Cancer through BHLHE41-Mediated Suppression of MLH1 in another window
Includes: Supplementary data
Journal Articles

GLI1 Modulates EMT in Pancreatic Cancer—Letter

Shingo Inaguma, Kenji Kasai, Mitsuyoshi Hashimoto, Hiroshi Ikeda
Journal: Cancer Research
Cancer Res (2012) 72 (14): 3702–3703.
https://doi.org/10.1158/0008-5472.CAN-12-0379
Published: 15 July 2012
View article titled, GLI1 Modulates EMT in Pancreatic Cancer—Letter
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Journal Articles

Abstract 2530: Antimyeloma activity of a small molecule multi-targeted kinase inhibitor, AT9283, via potent aurora kinase and STAT3 inhibition

Loredana Santo, Teru Hideshima, Diana Cirstea, Erik A. Nelson, Madhavi L. Bandi, Gullu Gorgun, Sonia Vallet, Samantha Pozzi, Kishan Patel, Hiroshi Ikeda, Giulia Perrone, Yiguo Hu, Dharminder Chauhan, Matthew Squires, Nikhil C. Munshi, Kenneth C. Anderson, Noopur Raje
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2530.
https://doi.org/10.1158/1538-7445.AM10-2530
Published: 15 April 2010
View article titled, Abstract 2530: Antimyeloma activity of a small molecule multi-targeted kinase inhibitor, AT9283, via potent aurora kinase and STAT3 inhibition
Journal Articles

Abstract 3895: GLI1 induces the expression of bHLH type transcriptional repressor DEC2 in pancreatic cancer cells

Shingo Inaguma, Kenji Kasai, Hiroshi Ikeda
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3895.
https://doi.org/10.1158/1538-7445.AM10-3895
Published: 15 April 2010
View article titled, Abstract 3895: GLI1 induces the expression of bHLH type transcriptional repressor <em>DEC2</em> in pancreatic cancer cells
Journal Articles

BCL9 Promotes Tumor Progression by Conferring Enhanced Proliferative, Metastatic, and Angiogenic Properties to Cancer Cells

Mala Mani, Daniel E. Carrasco, Yunyu Zhang, Kohichi Takada, Moshe E. Gatt, Jui Dutta-Simmons, Hiroshi Ikeda, Felipe Diaz-Griffero, Victor Pena-Cruz, Monica Bertagnolli, Lois L. Myeroff, Sanford D. Markowitz, Kenneth C. Anderson, Daniel R. Carrasco
Journal: Cancer Research
Cancer Res (2009) 69 (19): 7577–7586.
https://doi.org/10.1158/0008-5472.CAN-09-0773
Published: 01 October 2009
View article titled, BCL9 Promotes Tumor Progression by Conferring Enhanced Proliferative, Metastatic, and Angiogenic Properties to Cancer Cells
Open the PDF for BCL9 Promotes Tumor Progression by Conferring Enhanced Proliferative, Metastatic, and Angiogenic Properties to Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Abstract #1994: A novel multi-targeted small molecule inhibitor RGB 286638 triggers apoptosis and necrosis in multiple myeloma via dual cell death pathways

Diana Cirstea, Teru Hideshima, Loredana Santo, Sonia Vallet, Samantha Pozzi, Nileshwari Vaghela, Hiroshi Ikeda, Kishan Patel, Hannes Loferer, Gullu Gorgun, Giulia Perrone, Elisabetta Calabrese, Nikhil Munshi, Kenneth Anderson, Noopur Raje
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1994.
Published: 01 May 2009
View article titled, Abstract #1994: A novel multi-targeted small molecule inhibitor RGB 286638 triggers apoptosis and necrosis in multiple myeloma via dual cell death pathways
Journal Articles

SCL/TAL1 Interrupting Locus Derepresses GLI1 from the Negative Control of Suppressor-of-Fused in Pancreatic Cancer Cell

Kenji Kasai, Shingo Inaguma, Akiko Yoneyama, Kazuhiro Yoshikawa, Hiroshi Ikeda
Journal: Cancer Research
Cancer Res (2008) 68 (19): 7723–7729.
https://doi.org/10.1158/0008-5472.CAN-07-6661
Published: 30 September 2008
View article titled, SCL/TAL1 Interrupting Locus Derepresses GLI1 from the Negative Control of Suppressor-of-Fused in Pancreatic Cancer Cell
Open the PDF for SCL/TAL1 Interrupting Locus Derepresses GLI1 from the Negative Control of Suppressor-of-Fused in Pancreatic Cancer Cell in another window
Includes: Supplementary data
Journal Articles

Dual inhibition of the Akt pathway by Rapamycin and Perifosine induces synergistic anti-tumor activity in multiple myeloma

Diana Cirstea, Teru Hideshima, Hiroshi Ikeda, Samantha Pozzi, Sonia Vallet, Nileshwari Vaghela, Yutaka Okawa, Loredana Santo, Chhetri Shweta, Gaurav Chhetri, Chirayu Patel, Hua Yan, Tanyel Kiziltepe, Iris Breitkreutz, Kenneth Anderson, Noopur Raje
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4181.
Published: 01 May 2008
View article titled, Dual inhibition of the Akt pathway by Rapamycin and Perifosine induces synergistic anti-tumor activity in multiple myeloma
Journal Articles

Epigenetic modulation by VidazaTM induces apoptosis and overcomes in vitro drug resistance in human multiple myeloma cells.

Tanyel Kiziltepe, Laurence Catley, Teru Hideshima, Noopur Raje, Yasui Hiroshi, Sonia Vallet, Hiroshi Ikeda, Yutaka Okawa, Kenneth Anderson
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 3193.
Published: 01 May 2007
View article titled, Epigenetic modulation by Vidaza<sup>TM </sup>induces apoptosis and overcomes <em>in vitro</em> drug resistance in human multiple myeloma cells.