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Hiromitsu Hayashi
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Journal Articles

Abstract 4824: Intracellular ferritin expression levels regulate growth and resistance to ferroptosis in pancreatic cancer cell lines

Masataka Maruno, Yo-hei Kanamori, Takashi Matsumoto, Yuta Shiraishi, Toru Takematsu, Tatsunori Miyata, Kosuke Mima, Shigeki Nakagawa, Hidetoshi Nitta, Hiromitsu Hayashi, Toshiro Moroishi, Hideo Baba
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4824.
https://doi.org/10.1158/1538-7445.AM2023-4824
Published: 04 April 2023
View article titled, Abstract 4824: Intracellular ferritin expression levels regulate growth and resistance to ferroptosis in pancreatic cancer cell lines
Journal Articles

Abstract 3709: Hyperglycemia induces metabolic reprogramming and promotes epithelial-mesenchymal transitions in pancreatic cancer: an in vitro and in vivo experiment

Zhao Liu, Hiromitsu Hayashi, Kazuki Matsumura, Yoko Ogata, Hiroki Sato, Yuta Shiraishi, Norio Uemura, Tatsunori Miyata, Takaaki Higashi, Shigeki Nakagawa, Kosuke Mima, Katsunori Imai, Hideo Baba
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3709.
https://doi.org/10.1158/1538-7445.AM2023-3709
Published: 04 April 2023
View article titled, Abstract 3709: Hyperglycemia induces metabolic reprogramming and promotes epithelial-mesenchymal transitions in pancreatic cancer: an in vitro and in vivo experiment
Journal Articles

Abstract 2239: Investigation of the molecular biological significance of YAP/TAZ expression in PNEN

Yuta Shiraishi, Hiromitsu Hayashi, Daisuke Ogawa, Shinsei Yumoto, Hiroki Sato, Takashi Matsumoto, Toru Takematsu, Masataka Maruno, Masayo Tsukamoto, Tatsunori Miyata, Shigeki Nakagawa, Kosuke Mima, Hidetoshi Nitta, Hideo Baba
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2239.
https://doi.org/10.1158/1538-7445.AM2023-2239
Published: 04 April 2023
View article titled, Abstract 2239: Investigation of the molecular biological significance of YAP/TAZ expression in PNEN
Journal Articles

Extracellular Vesicles from Cancer-Associated Fibroblasts Containing Annexin A6 Induces FAK-YAP Activation by Stabilizing β1 Integrin, Enhancing Drug Resistance

Tomoyuki Uchihara, Keisuke Miyake, Atsuko Yonemura, Yoshihiro Komohara, Rumi Itoyama, Mayu Koiwa, Tadahito Yasuda, Kota Arima, Kazuto Harada, Kojiro Eto, Hiromitsu Hayashi, Masaaki Iwatsuki, Shiro Iwagami, Yoshifumi Baba, Naoya Yoshida, Masakazu Yashiro, Mari Masuda, Jaffer A. Ajani, Patrick Tan, Hideo Baba, Takatsugu Ishimoto
Journal: Cancer Research
Cancer Res (2020) 80 (16): 3222–3235.
https://doi.org/10.1158/0008-5472.CAN-19-3803
Published: 14 August 2020
View article titled, Extracellular Vesicles from Cancer-Associated Fibroblasts Containing Annexin A6 Induces FAK-YAP Activation by Stabilizing β1 Integrin, Enhancing Drug Resistance
Open the PDF for Extracellular Vesicles from Cancer-Associated Fibroblasts Containing Annexin A6 Induces FAK-YAP Activation by Stabilizing β1 Integrin, Enhancing Drug Resistance in another window
Includes: Multimedia, Supplementary data
Journal Articles

Abstract 1766: High expression of ARHGEF2 is associated with poor prognosis via c-Myc signaling in patients with pancreatic cancer

Yosuke Nakao, Shigeki Nakagawa, Yo-ichi Yamashita, Rumi Itoyama, Toshihiko Yusa, Naoki Umezaki, Takanobu Yamao, Tatsunori Miyata, Hirohisa Okabe, Katsunori Imai, Hiromitsu Hayashi, Akira Chikamoto, Hideo Baba
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1766.
https://doi.org/10.1158/1538-7445.AM2019-1766
Published: 01 July 2019
View article titled, Abstract 1766: High expression of ARHGEF2 is associated with poor prognosis via c-Myc signaling in patients with pancreatic cancer
Journal Articles

Abstract 2023: Cellular senescence, represented by expression of caveolin-1, in cancer-associated fibroblasts promotes tumor Invasion in pancreatic cancer cellular

Takanobu Yamao, Yo-ichi Yamashita, Kensuke Yamamura, Naoki Umezaki, Rumi Itoyama, Yosuke Nakao, Toshihiko Yusa, Tatsunori Miyata, Shigeki Nakagawa, Hirohisa Okabe, Katsunori Imai, Hiromitsu Hayashi, Akira Chikamoto, Takatoshi Ishiko, Hideo Baba
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2023.
https://doi.org/10.1158/1538-7445.AM2019-2023
Published: 01 July 2019
View article titled, Abstract 2023: Cellular senescence, represented by expression of caveolin-1, in cancer-associated fibroblasts promotes tumor Invasion in pancreatic cancer cellular
Journal Articles

Abstract 1084: The role of tumor-associated neutrophils (TAN) and CD8 positive T lymphocyte in the progression of hepatocellular carcinoma (HCC)

Toshihiko Yusa, Hirohisa Okabe, Yo-ichi Yamashita, Takanobu Yamao, Naoki Umezaki, Tatsunori Miyata, Shigeki Nakagawa, Hiromitsu Hayashi, Katsunori Imai, Akira Chikamoto, Takatoshi Ishiko, Hideo Baba
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1084.
https://doi.org/10.1158/1538-7445.AM2019-1084
Published: 01 July 2019
View article titled, Abstract 1084: The role of tumor-associated neutrophils (TAN) and CD8 positive T lymphocyte in the progression of hepatocellular carcinoma (HCC)
Journal Articles

Abstract 2854: Clinical significance of Cofilin-1 expression in pancreatic cancer

Rumi Itoyama, Shigeki Nakagawa, Toshihiko Yusa, Yosuke Nakao, Takanobu Yamao, Naoki Umezaki, Tatsunori Miyata, Hirohisa Okabe, Hiromitsu Hayashi, Katsunori Imai, Yo-ichi Yamashita, Akira Chikamoto, Hideo Baba
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2854.
https://doi.org/10.1158/1538-7445.AM2019-2854
Published: 01 July 2019
View article titled, Abstract 2854: Clinical significance of Cofilin-1 expression in pancreatic cancer
Journal Articles

Abstract 38: The clinical significance of GLUT1 expression in gastrointestinal stromal tumor

Daisuke Kuroda, Junji Kurashige, Masaaki Iwatsuki, Tsugio Eto, Yuka Tamaoki, Mayuko Ohuchi, Kenichi Nakamura, Ryuma Tokunaga, Hironobu Shigaki, Hiromitsu Hayashi, Takatsugu Ishimoto, Yoshifumi Baba, Yasuo Sakamoto, Naoya Yoshida, Hideo Baba
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 38.
https://doi.org/10.1158/1538-7445.AM2016-38
Published: 15 July 2016
View article titled, Abstract 38: The clinical significance of GLUT1 expression in gastrointestinal stromal tumor
Journal Articles

Abstract 5073: C5a receptor promotes invasive ability of gastric cancer

Takayoshi Kaida, Hidetoshi Nitta, Yuki Kitano, Kensuke Yamamura, Risa Inoue, Kota Arima, Takaaki Higashi, Katunobu Taki, Hiromitsu Hayashi, Katsunori Imai, Daisuke Hashimoto, Akira Chikamoto, Toru Beppu, Hide Baba
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 5073.
https://doi.org/10.1158/1538-7445.AM2016-5073
Published: 15 July 2016
View article titled, Abstract 5073: C5a receptor promotes invasive ability of gastric cancer
Journal Articles

An Imbalance in TAZ and YAP Expression in Hepatocellular Carcinoma Confers Cancer Stem Cell–like Behaviors Contributing to Disease Progression

Hiromitsu Hayashi, Takaaki Higashi, Naomi Yokoyama, Takayoshi Kaida, Keita Sakamoto, Yukiko Fukushima, Takatsugu Ishimoto, Hideyuki Kuroki, Hidetoshi Nitta, Daisuke Hashimoto, Akira Chikamoto, Eiji Oki, Toru Beppu, Hideo Baba
Journal: Cancer Research
Cancer Res (2015) 75 (22): 4985–4997.
https://doi.org/10.1158/0008-5472.CAN-15-0291
Published: 15 November 2015
View article titled, An Imbalance in TAZ and YAP Expression in Hepatocellular Carcinoma Confers Cancer Stem Cell–like Behaviors Contributing to Disease Progression
Open the PDF for An Imbalance in TAZ and YAP Expression in Hepatocellular Carcinoma Confers Cancer Stem Cell–like Behaviors Contributing to Disease Progression in another window
Includes: Supplementary data
Journal Articles

Abstract 897: CHOP-deficiency promotes chronic inflammation-induced pancreatic fibrosis

Katsunobu Taki, Masaki Ohmuraya, Daisuke Hashimoto, Kota Arima, Hideaki Takeyama, Takayoshi Kaida, Takaaki Higashi, Hidetoshi Nitta, Hiromitsu Hayashi, Akira Chikamoto, Toru Beppu, Kimi Araki, Hideo Baba
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 897.
https://doi.org/10.1158/1538-7445.AM2015-897
Published: 01 August 2015
View article titled, Abstract 897: CHOP-deficiency promotes chronic inflammation-induced pancreatic fibrosis
Journal Articles

Abstract 4146: Overexpression of C5a receptor becomes risk factor in gastric cancer

Takayoshi Kaida, Hidetoshi Nitta, Kota Arima, Hideaki Takeyama, Takaaki Higashi, Katunobu Taki, Hiromitsu Hayashi, Daisuke Hashimoto, Akira Chikamoto, Takatoshi Ishiko, Toru Beppu, Hideo Baba
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4146.
https://doi.org/10.1158/1538-7445.AM2015-4146
Published: 01 August 2015
View article titled, Abstract 4146: Overexpression of C5a receptor becomes risk factor in gastric cancer
Journal Articles

Abstract 3125: miR-9-3p plays a tumor-suppressor role by targeting TAZ (WWTR1) in hepatocellular carcinoma cells

Takaaki Higashi, Hiromitsu Hayashi, Hideaki Takeyama, Takayoshi Kaida, Kota Arima, Katsunobu Taki, Hirohisa Okabe, Hidetoshi Nitta, Daisuke Hashimoto, Akira Chikamoto, Toru Beppu, Hideo Baba
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3125.
https://doi.org/10.1158/1538-7445.AM2015-3125
Published: 01 August 2015
View article titled, Abstract 3125: miR-9-3p plays a tumor-suppressor role by targeting TAZ (WWTR1) in hepatocellular carcinoma cells
Journal Articles

Abstract 1175: Curcumin may have anticancer effect by normalizing cancer metabolic pathway

Hideaki Takeyama, Hiromitsu Hayashi, Takayoshi Kaida, Kota Arima, Katsunobu Taki, Takaaki Higashi, Hirohisa Okabe, Hidetoshi Nitta, Daisuke Hashimoto, Akira Chikamoto, Toru Beppu, Hideo Baba
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1175.
https://doi.org/10.1158/1538-7445.AM2015-1175
Published: 01 August 2015
View article titled, Abstract 1175: Curcumin may have anticancer effect by normalizing cancer metabolic pathway
Journal Articles

Abstract 1406: High expression of DPD and ALDH1 are associated with poor prognosis in pancreatic cancer

Kota Arima, Hirohisa Okabe, Daisuke Hashimoto, Takayoshi Kaida, Takaaki Higashi, Katsunobu Taki, Hideaki Takeyama, Hidetoshi Nitta, Hiromitsu Hayashi, Akira Chikamoto, Toru Beppu, Hideo Baba
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1406.
https://doi.org/10.1158/1538-7445.AM2015-1406
Published: 01 August 2015
View article titled, Abstract 1406: High expression of DPD and ALDH1 are associated with poor prognosis in pancreatic cancer
Journal Articles

Abstract 2700: LSKL peptide inhibits thrombospondin-1-mediated TGF-β signal activation and accelerates liver regeneration after hepatectomy in mice

Hideyuki Kuroki, Hiromitsu Hayashi, Shigeki Nakagawa, Keita Sakamoto, Takaaki Higashi, Hidetoshi Nitta, Daisuke Hashimoto, Akira Chikamoto, Toru Beppu, Hideo Baba
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2700.
https://doi.org/10.1158/1538-7445.AM2014-2700
Published: 01 October 2014
View article titled, Abstract 2700: LSKL peptide inhibits thrombospondin-1-mediated TGF-β signal activation and accelerates liver regeneration after hepatectomy in mice
Journal Articles

Abstract 408: The relationship between LINE-1 hypomethylation and fibrosis status in noncancerous liver tissues of hepatocellular carcinoma patients

Yoshifumi Baba, Kazuto Harada, Keisuke Kosumi, Hiromitsu Hayashi, Hidetoshi Nitta, Daisuke Hashimoto, Akira Chikamoto, Toru Beppu, Hideo Baba
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 408.
https://doi.org/10.1158/1538-7445.AM2014-408
Published: 01 October 2014
View article titled, Abstract 408: The relationship between LINE-1 hypomethylation and fibrosis status in noncancerous liver tissues of hepatocellular carcinoma patients
Journal Articles

Abstract 3520: TAZ (WWTR1), a key transcription co-activator of hippo-pathway, promotes hepatocellular carcinoma progression via PI3K/Akt/mTOR pathway

Hiromitsu Hayashi, Hideyuki Kuroki, Shigeki Nakagawa, Takaaki Higashi, Keita Sakamoto, Naomi Yokoyama, Takatoshi Ishiko, Toru Beppu, Hideo Baba
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3520.
https://doi.org/10.1158/1538-7445.AM2014-3520
Published: 01 October 2014
View article titled, Abstract 3520: TAZ (WWTR1), a key transcription co-activator of hippo-pathway, promotes hepatocellular carcinoma progression via PI3K/Akt/mTOR pathway
Journal Articles

Abstract 241: CHOP-deficiency promotes chronic inflammation-induced pancreatic fibrosis

Katsunobu Taki, Masaki Ohmuraya, Kazuya Sakata, Daisuke Hashimoto, Shinya Abe, Hidetoshi Nitta, Hiromitsu Hayashi, Akira Chikamoto, Toru Beppu, Hideo Baba
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 241.
https://doi.org/10.1158/1538-7445.AM2014-241
Published: 01 October 2014
View article titled, Abstract 241: CHOP-deficiency promotes chronic inflammation-induced pancreatic fibrosis