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Hiromi I. Wettersten
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Journal Articles

Integrin αvβ3 Upregulation in Response to Nutrient Stress Promotes Lung Cancer Cell Metabolic Plasticity

Arin Nam, Shashi Jain, Chengsheng Wu, Alejandro Campos, Ryan M. Shepard, Ziqi Yu, Joshua P. Reddy, Tami Von Schalscha, Sara M. Weis, Mark Onaitis, Hiromi I. Wettersten, David A. Cheresh
Journal: Cancer Research
Cancer Res (2024) 84 (10): 1630–1642.
https://doi.org/10.1158/0008-5472.CAN-23-2700
Published: 15 May 2024
View article titled, Integrin αvβ3 Upregulation in Response to Nutrient Stress Promotes Lung Cancer Cell Metabolic Plasticity
Open the PDF for Integrin αvβ3 Upregulation in Response to Nutrient Stress Promotes Lung Cancer Cell Metabolic Plasticity in another window
Includes: Supplementary data
Journal Articles

Abstract 3066: Lung cancer cells overcome nutrient stress by upregulating an integrin αvβ3/AMPK/OXPHOS axis

Arin Nam, Shashi Jain, Alejandro Campos, Ryan M. Shepard, Tami von Schalscha, Sara M. Weis, Hiromi I. Wettersten, David A. Cheresh
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3066.
https://doi.org/10.1158/1538-7445.AM2024-3066
Published: 22 March 2024
View article titled, Abstract 3066: Lung cancer cells overcome nutrient stress by upregulating an integrin αvβ3/AMPK/OXPHOS axis
Journal Articles

Abstract 2979: Pancreatic cancer cells upregulate LPAR4 in response to isolation stress to create a fibronectin-rich extracellular matrix niche and promote tumor initiation

Chengsheng Wu, Taha Rakhshandehroo, Hiromi I. Wettersten, Alejandro Campos, Tami Von Schalscha, Shashi Jain, Ziqi Yu, Jiali Tan, Evangeline Mose, Betzaira G. Childers, Andrew M. Lowy, Sara M. Weis, David A. Cheresh
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2979.
https://doi.org/10.1158/1538-7445.AM2024-2979
Published: 22 March 2024
View article titled, Abstract 2979: Pancreatic cancer cells upregulate LPAR4 in response to isolation stress to create a fibronectin-rich extracellular matrix niche and promote tumor initiation
Journal Articles

Abstract 4267: Inflammation mediated expression of integrin αvβ3 potentiates KRAS driven PDAC oncogenesis

Ryan M. Shepard, Alejandro D. Campos, Zachary M. Ortega, Hiromi I. Wettersten, Tami Von Schalscha, Sara M. Weis, David A. Cheresh
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4267.
https://doi.org/10.1158/1538-7445.AM2024-4267
Published: 22 March 2024
View article titled, Abstract 4267: Inflammation mediated expression of integrin αvβ3 potentiates KRAS driven PDAC oncogenesis
Journal Articles

Abstract 6358: Arming tumor-associated macrophages to inhibit cancer progression

Joshua P. Reddy, Ziqi Yu, Ryan M. Shepard, Tami Von Schalscha, Stephen J. McCormack, Sara M. Weis, David A. Cheresh, Hiromi I. Wettersten
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6358.
https://doi.org/10.1158/1538-7445.AM2024-6358
Published: 22 March 2024
View article titled, Abstract 6358: Arming tumor-associated macrophages to inhibit cancer progression
Journal Articles

Arming Tumor-Associated Macrophages to Reverse Epithelial Cancer Progression

Hiromi I. Wettersten, Sara M. Weis, Paulina Pathria, Tami Von Schalscha, Toshiyuki Minami, Judith A. Varner, David A. Cheresh
Journal: Cancer Research
Cancer Res (2019) 79 (19): 5048–5059.
https://doi.org/10.1158/0008-5472.CAN-19-1246
Published: 01 October 2019
View article titled, Arming Tumor-Associated Macrophages to Reverse Epithelial Cancer Progression
Open the PDF for Arming Tumor-Associated Macrophages to Reverse Epithelial Cancer Progression in another window
Includes: Supplementary data
Journal Articles

Abstract 3067: Galectin-3, a target for KRAS-addicted lung cancer

Laetitia Seguin, Maria F. Camargo, Hiromi I. Wettersten, Shumei Kato, Tami von Schalscha, Kathryn C. Elliott, Sara M. Weis, David A. Cheresh
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3067.
https://doi.org/10.1158/1538-7445.AM2017-3067
Published: 01 July 2017
View article titled, Abstract 3067: Galectin-3, a target for KRAS-addicted lung cancer
Journal Articles

Abstract 3966: Targeting integrin αvβ3-expressing cancer stem cells to manipulate tumor-associated macrophages

Hiromi I. Wettersten, Toshiyuki Minami, Megan M. Kaneda, Laetitia Seguin, Judith A. Varner, Sara M. Weis, David A. Cheresh
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3966.
https://doi.org/10.1158/1538-7445.AM2017-3966
Published: 01 July 2017
View article titled, Abstract 3966: Targeting integrin αvβ3-expressing cancer stem cells to manipulate tumor-associated macrophages
Journal Articles

Grade-Dependent Metabolic Reprogramming in Kidney Cancer Revealed by Combined Proteomics and Metabolomics Analysis

Hiromi I. Wettersten, A. Ari Hakimi, Dexter Morin, Cristina Bianchi, Megan E. Johnstone, Dallas R. Donohoe, Josephine F. Trott, Omran Abu Aboud, Steven Stirdivant, Bruce Neri, Robert Wolfert, Benjamin Stewart, Roberto Perego, James J. Hsieh, Robert H. Weiss
Journal: Cancer Research
Cancer Res (2015) 75 (12): 2541–2552.
https://doi.org/10.1158/0008-5472.CAN-14-1703
Published: 14 June 2015
View article titled, Grade-Dependent Metabolic Reprogramming in Kidney Cancer Revealed by Combined Proteomics and Metabolomics Analysis
Open the PDF for Grade-Dependent Metabolic Reprogramming in Kidney Cancer Revealed by Combined Proteomics and Metabolomics Analysis in another window
Includes: Supplementary data