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Journal Articles

Abstract 1669: Preclinical efficacy of Sym004, novel anti-EGFR antibody, in esophageal squamous cell carcinoma cell lines

Shota Fukuoka, Takashi Kojima, Yoshikatsu Koga, Mayumi Yamauchi, Rie Komatsuzaki, Kazuhiko Aoyagi, Hiroki Sasaki, Masahiro Yasunaga, Yasuhiro Matsumura, Toshio Kuronita, Toshihiko Doi, Atsushi Ohtsu
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1669.
https://doi.org/10.1158/1538-7445.AM2015-1669
Published: 01 August 2015
View article titled, Abstract 1669: Preclinical efficacy of Sym004, novel anti-EGFR antibody, in esophageal squamous cell carcinoma cell lines
Journal Articles

Abstract 412: SEC11A contributes to malignant progression through promotion of EGF and TGF-α secretion in gastric cancer.

Naohide Oue, Tetsutaro Hayashi, Reiko Ito, Akiko Nagatsuma, Kazuhiro Sentani, Naoya Sakamoto, Katsuhiro Anami, Naohiro Uraoka, Yutaka Naito, Kazuyoshi Yanagihara, Atsushi Ochiai, Hiroki Sasaki, Wataru Yasui
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 412.
https://doi.org/10.1158/1538-7445.AM2013-412
Published: 15 April 2013
View article titled, Abstract 412: SEC11A contributes to malignant progression through promotion of EGF and TGF-α secretion in gastric cancer.
Journal Articles

Abstract 5: Frequency of FGFR2 gene amplification in gastric cancer

Kazuko Matsumoto, Tokuzo Arao, Tetsuya Hamaguchi, Yasuhiro Shimada, Ken Kato, Ichiro Oda, Hirokazu Taniguchi, Fumiaki Koizumi, Kazuyoshi Yanagihara, Hiroki Sasaki, Yasuhide Yamada, Kazuto Nishio
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5.
https://doi.org/10.1158/1538-7445.AM2012-5
Published: 15 April 2012
View article titled, Abstract 5: Frequency of FGFR2 gene amplification in gastric cancer
Journal Articles

Podoplanin-Positive Fibroblasts Enhance Lung Adenocarcinoma Tumor Formation: Podoplanin in Fibroblast Functions for Tumor Progression

Ayuko Hoshino, Genichiro Ishii, Takashi Ito, Kazuhiko Aoyagi, Yoichi Ohtaki, Kanji Nagai, Hiroki Sasaki, Atsushi Ochiai
Journal: Cancer Research
Cancer Res (2011) 71 (14): 4769–4779.
https://doi.org/10.1158/0008-5472.CAN-10-3228
Published: 14 July 2011
View article titled, Podoplanin-Positive Fibroblasts Enhance Lung Adenocarcinoma Tumor Formation: Podoplanin in Fibroblast Functions for Tumor Progression
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Includes: Supplementary data
Journal Articles

Unique microRNA signatures associated with progression and prognosis of gastric cancer

Tetsuya Ueda, Stefano Volinia, Hiroshi Okumura, Masayoshi Shimizu, Cristian Taccioli, Hansjuerg Alder, Chang-gong Liu, Naohide Oue, Wataru Yasui, Kazuhiro Yoshida, Hiroki Sasaki, Sachiyo Nomura, Michio Kaminishi, George Calin, Carlo Croce
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5016.
Published: 01 May 2008
View article titled, Unique microRNA signatures associated with progression and prognosis of gastric cancer
Journal Articles

AZD2171 shows potent anti-tumor activity against gastric cancer expressing variant K-SAM/FGFR2

Masayuki Takeda, Tokuzo Arao, Hideyuki Yokote, Kazuko Sakai, Hideharu Kimura, Kazuyoshi Yanagihara, Hiroki Sasaki, Tomohide Tamura, Nagahiro Saijo, Kazuto Nishio
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 890.
Published: 15 April 2006
View article titled, AZD2171 shows potent anti-tumor activity against gastric cancer expressing variant K-SAM/FGFR2
Journal Articles

Hedgehog signal activation in esophageal epithelium and in tumor

Noriyuki Isohata, Masahide Fukaya, Hiroyuki Ohta, Kazuhiko Aoyagi, Hiroyuki Daiko, Yukihiro Nakanishi, Kazuhiko Yoshimatsu, Kenji Ogawa, Teruhiko Yoshida, Hiroki Sasaki
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 629.
Published: 15 April 2006
View article titled, Hedgehog signal activation in esophageal epithelium and in tumor
Journal Articles

Discovery of Aberrant Expression of R-RAS by Cancer-Linked DNA Hypomethylation in Gastric Cancer Using Microarrays

Michiko Nishigaki, Kazuhiko Aoyagi, Inaho Danjoh, Masahide Fukaya, Kazuyoshi Yanagihara, Hiromi Sakamoto, Teruhiko Yoshida, Hiroki Sasaki
Journal: Cancer Research
Cancer Res (2005) 65 (6): 2115–2124.
https://doi.org/10.1158/0008-5472.CAN-04-3340
Published: 21 March 2005
View article titled, Discovery of Aberrant Expression of <em>R-RAS</em> by Cancer-Linked DNA Hypomethylation in Gastric Cancer Using Microarrays
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Journal Articles

Enhanced Skin Carcinogenesis in Cyclin D1-conditional Transgenic Mice: Cyclin D1 Alters Keratinocyte Response to Calcium-induced Terminal Differentiation

Hanako Yamamoto, Takahiro Ochiya, Fumitaka Takeshita, Hiroyasu Toriyama-Baba, Kotaro Hirai, Hideo Sasaki, Hiroki Sasaki, Hiromi Sakamoto, Teruhiko Yoshida, Izumu Saito, Masaaki Terada
Journal: Cancer Research
Cancer Res (2002) 62 (6): 1641–1647.
Published: 15 March 2002
View article titled, Enhanced Skin Carcinogenesis in Cyclin D1-conditional Transgenic Mice: <subtitle>Cyclin D1 Alters Keratinocyte Response to Calcium-induced Terminal Differentiation</subtitle>
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Journal Articles

Absence of Endothelial Cells, Central Necrosis, and Fibrosis Are Associated with Aggressive Inflammatory Breast Cancer

Kazuo Shirakawa, Hitoshi Tsuda, Yuji Heike, Kazunori Kato, Rumiko Asada, Motoko Inomata, Hiroki Sasaki, Fujio Kasumi, Masataka Yoshimoto, Toshihiko Iwanaga, Fumio Konishi, Masaaki Terada, Hiro Wakasugi
Journal: Cancer Research
Cancer Res (2001) 61 (2): 445–451.
Published: 01 January 2001
View article titled, Absence of Endothelial Cells, Central Necrosis, and Fibrosis Are Associated with Aggressive Inflammatory Breast Cancer
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Journal Articles

Deletion of the Carboxyl-Terminal Exons of K-sam/FGFR2 by Short Homology-mediated Recombination, Generating Preferential Expression ofSpecific Messenger RNAs

Tetsuya Ueda, Hiroki Sasaki, Yoshitaka Kuwahara, Masahiko Nezu, Tetsuo Shibuya, Hiromi Sakamoto, Hideshi Ishii, Kazuyoshi Yanagihara, Ken-ichi Mafune, Masatoshi Makuuchi, Masaaki Terada
Journal: Cancer Research
Cancer Res (1999) 59 (24): 6080–6086.
Published: 15 December 1999
View article titled, Deletion of the Carboxyl-Terminal Exons of K-<em>sam</em>/<em>FGFR2</em> by Short Homology-mediated Recombination, Generating Preferential Expression ofSpecific Messenger RNAs
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Journal Articles

Homologous Recombination between p53 and Its Pseudogene in a Radiation-induced Mouse Tumor

Hiroshi Tanooka, Akira Ootsuyama, Hiroki Sasaki
Journal: Cancer Research
Cancer Res (1998) 58 (24): 5649–5651.
Published: 01 December 1998
View article titled, Homologous Recombination between <em>p53</em> and Its Pseudogene in a Radiation-induced Mouse Tumor
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Journal Articles

Presence of Streptococcus anginosus DNA in Esophageal Cancer, Dysplasia of Esophagus, and Gastric Cancer

Hiroki Sasaki, Tomoki Ishizuka, Manabu Muto, Masahiko Nezu, Yukihiro Nakanishi, Yoshishige Inagaki, Haruo Watanabe, Hiroshi Watanabe, Masaaki Terada
Journal: Cancer Research
Cancer Res (1998) 58 (14): 2991–2995.
Published: 01 July 1998
View article titled, Presence of <em>Streptococcus anginosus</em> DNA in Esophageal Cancer, Dysplasia of Esophagus, and Gastric Cancer
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Journal Articles

Isolation of a Candidate Gene, CAB1, for Cholesterol Transport to Mitochondria from the c-ERBB-2 Amplicon by a Modified cDNA Selection Method

Nobu Akiyama, Hiroki Sasaki, Tomoki Ishizuka, Tatsuya Kishi, Hiromi Sakamoto, Masahiko Onda, Hisamaru Hirai, Yoshio Yazaki, Takashi Sugimura, Masaaki Terada
Journal: Cancer Research
Cancer Res (1997) 57 (16): 3548–3553.
Published: 01 August 1997
View article titled, Isolation of a Candidate Gene, <em>CAB1</em>, for Cholesterol Transport to Mitochondria from the c-<em>ERBB</em>-2 Amplicon by a Modified cDNA Selection Method
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Journal Articles

Mutation Frequency of the p16/CDKN2 Gene in Primary Cancers in the Upper Digestive Tract

Hiroyasu Igaki, Hiroki Sasaki, Yuji Tachimori, Hoichi Kato, Hiroshi Watanabe, Taizo Kimura, Yukio Harada, Takashi Sugimura, Masaaki Terada
Journal: Cancer Research
Cancer Res (1995) 55 (15): 3421–3423.
Published: 01 August 1995
View article titled, Mutation Frequency of the <em>p16/CDKN2</em> Gene in Primary Cancers in the Upper Digestive Tract
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Journal Articles

Highly Efficient Method for Obtaining a Subtracted Genomic DNA Library by the Modified In-Gel Competitive Reassociation Method

Hiroki Sasaki, Shintaro Nomura, Nobu Akiyama, Atsuhi Takahashi, Takashi Sugimura, Michio Oishi, Masaaki Terada
Journal: Cancer Research
Cancer Res (1994) 54 (22): 5821–5823.
Published: 01 November 1994
View article titled, Highly Efficient Method for Obtaining a Subtracted Genomic DNA Library by the Modified In-Gel Competitive Reassociation Method
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Journal Articles

Markedly Increased Amounts of Messenger RNAs for Vascular Endothelial Growth Factor and Placenta Growth Factor in Renal Cell Carcinoma Associated with Angiogenesis

Atsushi Takahashi, Hiroki Sasaki, Sun Jin Kim, Ken-ichi Tobisu, Tadao Kakizoe, Taiji Tsukamoto, Yoshiaki Kumamoto, Takashi Sugimura, Masaaki Terada
Journal: Cancer Research
Cancer Res (1994) 54 (15): 4233–4237.
Published: 01 August 1994
View article titled, Markedly Increased Amounts of Messenger RNAs for Vascular Endothelial Growth Factor and Placenta Growth Factor in Renal Cell Carcinoma Associated with Angiogenesis
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Journal Articles

Preferential Alternative Splicing in Cancer Generates a K-sam Messenger RNA with Higher Transforming Activity

Hiroshi Itoh, Yutaka Hattori, Hiromi Sakamoto, Hideshi Ishii, Tatsuya Kishi, Hiroki Sasaki, Teruhiko Yoshida, Masashi Koono, Takashi Sugimura, Masaaki Terada
Journal: Cancer Research
Cancer Res (1994) 54 (12): 3237–3241.
Published: 01 June 1994
View article titled, Preferential Alternative Splicing in Cancer Generates a K-<em>sam</em> Messenger RNA with Higher Transforming Activity
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Journal Articles

Messenger RNA Levels of Five Genes Located at Chromosome 11q13 in B-Cell Tumors with Chromosome Translocation t(11;14)(q13;q32)

Nobu Akiyama, Hiroyuki Tsuruta, Hiroki Sasaki, Hiromi Sakamoto, Masaaki Hamaguchi, Yoshihisa Ohmura, Masao Seto, Ryuzo Ueda, Hisamaru Hirai, Yoshio Yazaki, Takashi Sugimura, Masaaki Terada
Journal: Cancer Research
Cancer Res (1994) 54 (2): 377–379.
Published: 01 January 1994
View article titled, Messenger RNA Levels of Five Genes Located at Chromosome 11q13 in B-Cell Tumors with Chromosome Translocation t(11;14)(q13;q32)
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Journal Articles

Isolation of the Complementary DNA Encoding a Mouse Heparin-binding Growth Factor Receptor with the Use of a Unique Kinase Insert Sequence

Osamu Katoh, Yutaka Hattori, Hiroki Sasaki, Hiromi Sakamoto, Kiyohide Fujimoto, Takuma Fujii, Takashi Sugimura, Masaaki Terada
Journal: Cancer Research
Cancer Res (1993) 53 (5): 1136–1141.
Published: 01 March 1993
View article titled, Isolation of the Complementary DNA Encoding a Mouse Heparin-binding Growth Factor Receptor with the Use of a Unique Kinase Insert Sequence
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