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Hirokazu Taniguchi
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Journal Articles

Abstract 3594: Exportin 1 inhibition as a therapeutic strategy for small cell lung cancer

Alvaro Quintanal-Villalonga, Hirokazu Taniguchi, Yuan Hao, Andrew Chow, Yingqian A. Zhan, Fathema Uddin, Viola Allaj, Parvathy Manoj, Nisargbhai S. Shah, Umesh K. Bhanot, Juan Qiu, Elisa de Stanchina, Richard P. Koche, Triparna Sen, John T. Poirier, Charles M. Rudin
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3594.
https://doi.org/10.1158/1538-7445.AM2022-3594
Published: 15 June 2022
View article titled, Abstract 3594: Exportin 1 inhibition as a therapeutic strategy for small cell lung cancer
Journal Articles

Abstract 1370: Targeting LSD1 rescues MHC-I antigen presentation in small cell lung cancer

Minh N. Nguyen, Hirokazu Taniguchi, Andrew Chow, Yingqian A. Zhan, Triparna Sen, Charles M. Rudin
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1370.
https://doi.org/10.1158/1538-7445.AM2022-1370
Published: 15 June 2022
View article titled, Abstract 1370: Targeting LSD1 rescues MHC-I antigen presentation in small cell lung cancer
Journal Articles

Abstract 658: AKT pathway as a therapeutic target to constrain lineage plasticity leading to histological transdifferentiation

Alvaro Quintanal-Villalonga, Hirokazu Taniguchi, Yingqian A. Zhan, Fathema Uddin, Viola Allaj, Parvathy Manoj, Nisargbhai S. Shah, Umesh K. Bhanot, Jacklynn Egger, Juan Qiu, Elisa de Stanchina, Natasha Rekhtman, Brian Houck-Loomis, Richard P. Koche, Helena A. Yu, Triparna Sen, Charles M. Rudin
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 658.
https://doi.org/10.1158/1538-7445.AM2022-658
Published: 15 June 2022
View article titled, Abstract 658: AKT pathway as a therapeutic target to constrain lineage plasticity leading to histological transdifferentiation
Journal Articles

Inhibition of XPO1 Sensitizes Small Cell Lung Cancer to First- and Second-Line Chemotherapy

Alvaro Quintanal-Villalonga, Hirokazu Taniguchi, Yuan Hao, Andrew Chow, Yingqian A. Zhan, Shweta S. Chavan, Fathema Uddin, Viola Allaj, Parvathy Manoj, Nisargbhai S. Shah, Joseph M. Chan, Michael Offin, Metamia Ciampricotti, Jordana Ray-Kirton, Jacklynn Egger, Umesh Bhanot, Irina Linkov, Marina Asher, Michael H. Roehrl, Juan Qiu, Elisa de Stanchina, Travis J. Hollmann, Richard P. Koche, Triparna Sen, John T. Poirier, Charles M. Rudin
Journal: Cancer Research
Cancer Res (2022) 82 (3): 472–483.
https://doi.org/10.1158/0008-5472.CAN-21-2964
Published: 02 February 2022
View article titled, Inhibition of XPO1 Sensitizes Small Cell Lung Cancer to First- and Second-Line Chemotherapy
Open the PDF for Inhibition of XPO1 Sensitizes Small Cell Lung Cancer to First- and Second-Line Chemotherapy in another window
Includes: Supplementary data
Journal Articles

Abstract 1705: Genetic analysis of thymoma and thymic carcinoma

Hiroyuki Yamaguchi, Hiroshi Gyotoku, Hirokazu Taniguchi, Daisuke Sasaki, Midori Shimada, Yosuke Dotsu, Hiroaki Senju, Norihito Kaku, Takaya Ikeda, Minoru Fukuda, Katsunori Yanagihara, Hiroshi Mukae
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1705.
https://doi.org/10.1158/1538-7445.AM2019-1705
Published: 01 July 2019
View article titled, Abstract 1705: Genetic analysis of thymoma and thymic carcinoma
Journal Articles

Abstract 313: AXL confers intrinsic resistance to osimertinib and the emergence of tolerant cells

Hirokazu Taniguchi, Tadaaki Yamada, Rong Wang, Keiko Tanimura, Akihiro Nishiyama, Azusa Tanimoto, Yuta Adachi, Shinji Takeuchi, Hiroyuki Yamaguchi, Minoru Fukuda, Koichi Takayama, Hiroshi Mukae, Seiji Yano
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 313.
https://doi.org/10.1158/1538-7445.AM2019-313
Published: 01 July 2019
View article titled, Abstract 313: AXL confers intrinsic resistance to osimertinib and the emergence of tolerant cells
Journal Articles

Abstract 844: Integrated analysis of genetic and epigenetic alterations in gastric carcinomas

Menghan Yang, Eri Arai, Hiromi Sakamoto, Hirohiko Totsuka, Hirokazu Taniguchi, Hitoshi Katai, Teruhiko Yoshida, Yae Kanai
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 844.
https://doi.org/10.1158/1538-7445.AM2019-844
Published: 01 July 2019
View article titled, Abstract 844: Integrated analysis of genetic and epigenetic alterations in gastric carcinomas
Journal Articles

Epithelial-to-Mesenchymal Transition Is a Mechanism of ALK Inhibitor Resistance in Lung Cancer Independent of ALK Mutation Status

Koji Fukuda, Shinji Takeuchi, Sachiko Arai, Ryohei Katayama, Shigeki Nanjo, Azusa Tanimoto, Akihiro Nishiyama, Takayuki Nakagawa, Hirokazu Taniguchi, Takeshi Suzuki, Tadaaki Yamada, Hiroshi Nishihara, Hironori Ninomiya, Yuichi Ishikawa, Satoko Baba, Kengo Takeuchi, Atsushi Horiike, Noriko Yanagitani, Makoto Nishio, Seiji Yano
Journal: Cancer Research
Cancer Res (2019) 79 (7): 1658–1670.
https://doi.org/10.1158/0008-5472.CAN-18-2052
Published: 01 April 2019
View article titled, Epithelial-to-Mesenchymal Transition Is a Mechanism of ALK Inhibitor Resistance in Lung Cancer Independent of <em>ALK</em> Mutation Status
Open the PDF for Epithelial-to-Mesenchymal Transition Is a Mechanism of ALK Inhibitor Resistance in Lung Cancer Independent of <em>ALK</em> Mutation Status in another window
Includes: Supplementary data
Journal Articles

Abstract 5843: The efficacy of a histone deacetylase inhibitor in combination with a MEK inhibitor in lung cancer cells harboring RAS mutations

Tadaaki Yamada, Joseph M. Amann, Azusa Tanimoto, Hirokazu Taniguchi, Takehito Shukuya, Seiji Yano, Koichi Takayama, David P. Carbone
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5843.
https://doi.org/10.1158/1538-7445.AM2018-5843
Published: 01 July 2018
View article titled, Abstract 5843: The efficacy of a histone deacetylase inhibitor in combination with a MEK inhibitor in lung cancer cells harboring RAS mutations
Journal Articles

Abstract 4917: High expression of miR-181c in tumor tissue as a recurrence marker of Dukes B colorectal cancer

Yoshikatsu Koga, Nobuyoshi Yamazaki, Hirokazu Taniguchi, Motohiro Kojima, Yukihide Kanemitsu, Norio Saito, Yasuhiro Matsumura
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4917.
https://doi.org/10.1158/1538-7445.AM2016-4917
Published: 15 July 2016
View article titled, Abstract 4917: High expression of miR-181c in tumor tissue as a recurrence marker of Dukes B colorectal cancer
Journal Articles

Abstract 4763: Targeted therapy by MET inhibitors against small-cell lung cancer with aberrant activation of HGF/MET pathway

Hirokazu Taniguchi, Shinji Takeuchi, Koji Fukuda, Tadaaki Yamada, Shuichi Sakamoto, Manabu Kawada, Seiji Yano
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4763.
https://doi.org/10.1158/1538-7445.AM2016-4763
Published: 15 July 2016
View article titled, Abstract 4763: Targeted therapy by MET inhibitors against small-cell lung cancer with aberrant activation of HGF/MET pathway
Journal Articles

Abstract 1048: Chromatin remodelers are frequently disrupted by epigenetic and genetic alterations at an early stage of carcinogenesis

Hideyuki Takeshima, Tohru Niwa, Takamasa Takahashi, Takayuki Ando, Hirokazu Taniguchi, Hitoshi Katai, Toshiro Sugiyama, Toshikazu Ushijima
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1048.
https://doi.org/10.1158/1538-7445.AM2015-1048
Published: 01 August 2015
View article titled, Abstract 1048: Chromatin remodelers are frequently disrupted by epigenetic and genetic alterations at an early stage of carcinogenesis
Journal Articles

Abstract 4657: MET amplification as a potential therapeutic target in gastric cancer.

Hisato Kawakami, Isamu Okamoto, Tokuzo Arao, Wataru Okamoto, Kazuko Matsumoto, Hirokazu Taniguchi, Kiyoko Kuwata, Haruka Yamaguchi, Kazuto Nishio, Kazuhiko Nakagawa, Yasuhide Yamada
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4657.
https://doi.org/10.1158/1538-7445.AM2013-4657
Published: 15 April 2013
View article titled, Abstract 4657: MET amplification as a potential therapeutic target in gastric cancer.
Journal Articles

Induction of the Stem-like Cell Regulator CD44 by Rho Kinase Inhibition Contributes to the Maintenance of Colon Cancer–Initiating Cells

Hirokazu Ohata, Tatsuya Ishiguro, Yuki Aihara, Ai Sato, Hiroaki Sakai, Shigeki Sekine, Hirokazu Taniguchi, Takayuki Akasu, Shin Fujita, Hitoshi Nakagama, Koji Okamoto
Journal: Cancer Research
Cancer Res (2012) 72 (19): 5101–5110.
https://doi.org/10.1158/0008-5472.CAN-11-3812
Published: 30 September 2012
View article titled, Induction of the Stem-like Cell Regulator CD44 by Rho Kinase Inhibition Contributes to the Maintenance of Colon Cancer–Initiating Cells
Open the PDF for Induction of the Stem-like Cell Regulator CD44 by Rho Kinase Inhibition Contributes to the Maintenance of Colon Cancer–Initiating Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 4089: Identification of a DNA methylation marker to detect the presence of lymph node metastases of gastric cancers

Yasuyuki Shigematsu, Tohru Niwa, Satoshi Yamashita, Hirokazu Taniguchi, Ryoji Kushima, Hitoshi Katai, Masao Ichinose, Toshikazu Ushijima
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4089.
https://doi.org/10.1158/1538-7445.AM2012-4089
Published: 15 April 2012
View article titled, Abstract 4089: Identification of a DNA methylation marker to detect the presence of lymph node metastases of gastric cancers
Journal Articles

Abstract 5: Frequency of FGFR2 gene amplification in gastric cancer

Kazuko Matsumoto, Tokuzo Arao, Tetsuya Hamaguchi, Yasuhiro Shimada, Ken Kato, Ichiro Oda, Hirokazu Taniguchi, Fumiaki Koizumi, Kazuyoshi Yanagihara, Hiroki Sasaki, Yasuhide Yamada, Kazuto Nishio
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5.
https://doi.org/10.1158/1538-7445.AM2012-5
Published: 15 April 2012
View article titled, Abstract 5: Frequency of FGFR2 gene amplification in gastric cancer
Journal Articles

Abstract 3361: Immunohistochemical analysis of CD133/44 expression in surgical specimens of squamous cell carcinoma of the esophagus after neoadjuvant chemotherapy

Takako Eguchi Nakajima, Hiroshi Yoshida, Hirokazu Taniguchi, Kenkichi Masutomi, Tadakazu Shimoda, Yasuhide Yamada
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3361.
https://doi.org/10.1158/1538-7445.AM10-3361
Published: 15 April 2010
View article titled, Abstract 3361: Immunohistochemical analysis of CD133/44 expression in surgical specimens of squamous cell carcinoma of the esophagus after neoadjuvant chemotherapy
Journal Articles

Abstract 3364: Evaluation of CD133/CD44 expression level in resected gastric cancer tissues after neoadjuvant chemotherapy

Hiroshi Yoshida, Takako Eguchi Nakajima, Hirokazu Taniguchi, Yousuke Horita, Kenkichi Masutomi, Tadakazu Shimoda, Yasuhide Yamada
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3364.
https://doi.org/10.1158/1538-7445.AM10-3364
Published: 15 April 2010
View article titled, Abstract 3364: Evaluation of CD133/CD44 expression level in resected gastric cancer tissues after neoadjuvant chemotherapy
Journal Articles

Quantification of CD10 mRNA in colorectal cancer and relationship between mRNA expression and liver metastasis

Shin Fujita, Seiichiro Yamamoto, Takayuki Akasu, Yoshihiro Moriya, Hirokazu Taniguchi, Tadakazu Shimoda
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 1772.
Published: 01 May 2007
View article titled, Quantification of CD10 mRNA in colorectal cancer and relationship between mRNA expression and liver metastasis
Journal Articles

Stem cell marker CD133 / prominin-1 is expressed in gastric cancer

Tokuzo Arao, Yasuhide Yamada, Hirokazu Taniguchi, Makoto Kawaishi, Terufumi Kato, Junya Fukai, Kazuko Sakai, Masayuki Takeda, Hideharu Kimura, Tatsu Shimoyama, Hideyuki Yokote, Kazuto Nishio
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 77.
Published: 15 April 2006
View article titled, Stem cell marker CD133 / prominin-1 is expressed in gastric cancer