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Hirokazu Nagawa
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Journal Articles

Abstract 4841: Inhibition of autophagy potentiates the anti-angiogenic effects of sulforaphane

Takeshi Nishikawa, Masaya Hiyoshi, Nelson H. Tsuno, Yurai Okaji, Eiji Sunami, Yasutaka Shuno, Kazuhito Sasaki, Kumiko Hongo, Manabu Kaneko, Kazushige Kawai, Joji Kitayama, Koki Takahashi, Hirokazu Nagawa
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4841.
https://doi.org/10.1158/1538-7445.AM10-4841
Published: 15 April 2010
View articletitled, Abstract 4841: Inhibition of autophagy potentiates the anti-angiogenic effects of sulforaphane
Journal Articles

Abstract 3367: CD133- colorectal cancer cells have higher chemo-resistance ability than CD133+cells

Kumiko Hongo, Junichirou Tanaka, Nelson H. Tuno, Takeshi Nishikawa, Yasutaka Shuno, Kazuhito Sasaki, Manabu Kaneko, Masaya Hiyoshi, Kazushige Kawai, Shin Sasaki, Eiji Sunami, Joji Kitayama, Koki Takahashi, Hirokazu Nagawa
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3367.
https://doi.org/10.1158/1538-7445.AM10-3367
Published: 15 April 2010
View articletitled, Abstract 3367: CD133- colorectal cancer cells have higher chemo-resistance ability than CD133+cells
Journal Articles

Abstract 85: Chloroquine potentiates the 5-fluorouracil-induced cell cycle arrest on HT-29 colon cancer cells

Kazuhito Sasaki, Nelson H. Tsuno, Eiji Sunami, Giichiro Tsurita, Yurai Okaji, Kazushige Kawai, Takeshi Nishikawa, Yasutaka Shuno, Kumiko Hongo, Manabu Kaneko, Masaya Hiyoshi, Joji Kitayama, Koki Takahashi, Hirokazu Nagawa
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 85.
https://doi.org/10.1158/1538-7445.AM10-85
Published: 15 April 2010
View articletitled, Abstract 85: Chloroquine potentiates the 5-fluorouracil-induced cell cycle arrest on HT-29 colon cancer cells
Journal Articles

Abstract 422: (-)-Epigallocatechin-3-gallate inhibits the metastatic potential of colon cancer

Manabu Kaneko, Nelson H. Tsuno, Kazushige Kawai, Takeshi Nishikawa, Yasutaka Shuno, Kazuhito Sasaki, Kumiko Hongo, Masaya Hiyoshi, Eiji Sunami, Joji Kitayama, Koki Takahashi, Hirokazu Nagawa
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 422.
https://doi.org/10.1158/1538-7445.AM10-422
Published: 15 April 2010
View articletitled, Abstract 422: (-)-Epigallocatechin-3-gallate inhibits the metastatic potential of colon cancer
Journal Articles

Abstract 1749: The downregulated expression of adiponectin receptors (AdipoR1, R2) in human colorectal cancer

Masaya Hiyoshi, Joji Kitayama, Nelson H. Tsuno, Eiji Sunami, Kazusige Kawai, Kensuke Otani, Takeshi Nishikawa, Yasutaka Shuno, Koji Yasuda, Kumiko Hongo, Yoshiko Kikkawa, Kazuhito Sasaki, Manabu Kaneko, Koki Takahashi, Hirokazu Nagawa
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1749.
https://doi.org/10.1158/1538-7445.AM10-1749
Published: 15 April 2010
View articletitled, Abstract 1749: The downregulated expression of adiponectin receptors (AdipoR1, R2) in human colorectal cancer
Journal Articles

Abstract 3908: Id1/Id3 Knockdown increases Chemosensitivity of Colorectal Cancer

Yasutaka Shuno, Nelson H. Tsuno, Yurai Okaji, Takeshi Nishikawa, Kumiko Hongo, Kazuhito Sasaki, Manabu Kaneko, Masaya Hiyoshi, Kazushige Kawai, Eiji Sunami, Joji Kitayama, Koki Takahashi, Hirokazu Nagawa
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3908.
https://doi.org/10.1158/1538-7445.AM10-3908
Published: 15 April 2010
View articletitled, Abstract 3908: Id1/Id3 Knockdown increases Chemosensitivity of Colorectal Cancer
Journal Articles

Abstract #168: CD133+ colorectal cancer cells have higher tumor-initiating ability than CD133- cells

Kumiko Hongo, Junichiro Tanaka, Nelson Tsuno, Takeshi Nishikawa, Yasutaka Shuno, Kazuhito Sasaki, Eiji Sunami, Joji Kitayama, Koki Takahashi, Hirokazu Nagawa
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 168.
Published: 01 May 2009
View articletitled, Abstract #168: CD133+ colorectal cancer cells have higher tumor-initiating ability than CD133- cells
Journal Articles

Abstract #2234: Id1/Id3 knockdown inhibits metastatic potential of pancreatic cancer

Yasutaka Shuno, Nelson Tsuno, Yurai Okaji, Takeshi Nishikawa, Kazuhito Sasaki, Kumiko Hongo, Eiji Sunami, Joji Kitayama, Koki Takahashi, Hirokazu Nagawa
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2234.
Published: 01 May 2009
View articletitled, Abstract #2234: Id1/Id3 knockdown inhibits metastatic potential of pancreatic cancer
Journal Articles

Abstract #384: Sulforaphane causes autophagy as a defense mechanism against apoptosis in human colon cancer cells

Takeshi Nishikawa, Nelson Tsuno, Yasutaka Shuno, Kazuhito Sasaki, Kumiko Hongo, Yurai Okaji, Eiji Sunami, Joji Kitayama, Koki Takahashi, Hirokazu Nagawa
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 384.
Published: 01 May 2009
View articletitled, Abstract #384: Sulforaphane causes autophagy as a defense mechanism against apoptosis in human colon cancer cells
Journal Articles

Abstract #383: Potentiation of pro-apoptotic effect of 5-Fluorouracil on HT29 colon cancer cells by inhibition of autophagy

Kazuhito Sasaki, Nelson Tsuno, Eiji Sunami, Giichiro Tsurita, Yurai Okaji, Takeshi Nishikawa, Yasutaka Syuno, Kumiko Hongo, Joji Kitayama, Koki Takahashi, Hirokazu Nagawa
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 383.
Published: 01 May 2009
View articletitled, Abstract #383: Potentiation of pro-apoptotic effect of 5-Fluorouracil on HT29 colon cancer cells by inhibition of autophagy
Journal Articles

Suppression of peritoneal metastasis of pancreatic cancer by Id1 and 3 double-knockdown.

Yasutaka Shuno, Nelson Tsuno, Takeshi Tsuchiya, Satomi Yoneyama, Jun Yamada, Junichiro Tanaka, Takeshi Nishikawa, Yurai Okaji, Giichiro Tsurita, Joji Kitayama, Koki Takahashi, Hirokazu Nagawa
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 333.
Published: 01 May 2008
View articletitled, Suppression of peritoneal metastasis of pancreatic cancer by Id1 and 3 double-knockdown.
Journal Articles

Sulforaphane induces apoptosis of endothelial progenitor cells

Takeshi Nishikawa, Nelson Tsuno, Takeshi Tsuchiya, Satomi Yoneyama, Jun Yamada, Yasutaka Shuno, Yurai Okaji, Joji Kitayama, Koki Takahashi, Hirokazu Nagawa
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4611.
Published: 01 May 2007
View articletitled, Sulforaphane induces apoptosis of endothelial progenitor cells
Journal Articles

The effects of Id1/Id3 double-knockdown in human pancreatic cancer cells

Yasutaka Shuno, Nelson Tsuno, Takeshi Tsuchiya, Satomi Yoneyama, Jun Yamada, Takeshi Nishikawa, Yurai Okaji, Koki Takahashi, Shin Sasaki, Joji Kitayama, Hirokazu Nagawa
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 1240.
Published: 01 May 2007
View articletitled, The effects of Id1/Id3 double-knockdown in human pancreatic cancer cells
Journal Articles

Id proteins regulate VEGF secretion of gastric cancer

Takeshi Tsuchiya, Nelson Tsuno, Yurai Okaji, Yasutaka Syuno, Jun Yamada, Satomi Yoneyama, Junichiro Tanaka, Takeshi Nishikawa, Shin Sasaki, Joji Kitayama, Takuya Osada, Koki Takahashi, Hirokazu Nagawa
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 3820.
Published: 01 May 2007
View articletitled, Id proteins regulate VEGF secretion of gastric cancer
Journal Articles

Anti-angiogenic activity of Zoledronic acid by inhibition of endothelial progenitor cells differentiation

Jun Yamada, Nelson Tsuno, Joji Kitayama, Yasutaka Shuno, Takeshi Nishikawa, Satomi Yaneyama, Takeshi Tsuchiya, Masahiro Asakage, Yurai Okaji, Takuya Osada, Shin Sasaki, Koki Takahashi, Hirokazu Nagawa
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4652.
Published: 01 May 2007
View articletitled, Anti-angiogenic activity of Zoledronic acid by inhibition of endothelial progenitor cells differentiation
Journal Articles

Left-sided microsatellite unstable colorectal cancers show less frequent methylation of hMLH1 and CpG island methylator phenotype than right-sided ones

Junichiro Tanaka, Toshiaki Watanabe, Takamitsu Kanazawa, Tomohiro Tada, Yoshihiro Kazama, Toshiaki Tanaka, Hirokazu Nagawa
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 1049.
Published: 01 May 2007
View articletitled, Left-sided microsatellite unstable colorectal cancers show less frequent methylation of hMLH1 and CpG island methylator phenotype than right-sided ones
Journal Articles

Leptin induces transactivation of Her2 as well as growth stimulating effect in breast cancer cell line with Her2-overexpression

Daisuke Souma, Joji Kitayama, Hiroharu Yamashita, Hideyo Miyato, Hirokazu Nagawa
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 2813.
Published: 01 May 2007
View articletitled, Leptin induces transactivation of Her2 as well as growth stimulating effect in breast cancer cell line with Her2-overexpression
Journal Articles

Endothelial dendritic cell vaccines inhibit tumor growth and metastasis of colon cancer through anti-angiogenesis

Satomi Yoneyama, Nelson Tsuno, Yurai Okaji, Kazushige Kawai, Takeshi Tsuchiya, Jun Yamada, Yasutaka Syuuno, Takeshi Nishikawa, Eiji Sunami, Takuya Osada, Joji Kitayama, Koki Takahashi, Hirokazu Nagawa
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 2737.
Published: 01 May 2007
View articletitled, Endothelial dendritic cell vaccines inhibit tumor growth and metastasis of colon cancer through anti-angiogenesis
Journal Articles

Distal Colorectal Cancers with Microsatellite Instability (MSI) Display Distinct Gene Expression Profiles that Are Different from Proximal MSI Cancers

Toshiaki Watanabe, Takashi Kobunai, Etsuko Toda, Yoko Yamamoto, Takamitsu Kanazawa, Yoshihiro Kazama, Junichiro Tanaka, Toshiaki Tanaka, Tsuyosi Konishi, Yoshihiro Okayama, Yoshikazu Sugimoto, Toshinori Oka, Shin Sasaki, Tetsuichiro Muto, Hirokazu Nagawa
Journal: Cancer Research
Cancer Res (2006) 66 (20): 9804–9808.
https://doi.org/10.1158/0008-5472.CAN-06-1163
Published: 17 October 2006
View articletitled, Distal Colorectal Cancers with Microsatellite Instability (MSI) Display Distinct Gene Expression Profiles that Are Different from Proximal MSI Cancers
Open the PDF for Distal Colorectal Cancers with Microsatellite Instability (MSI) Display Distinct Gene Expression Profiles that Are Different from Proximal MSI Cancers in another window
Includes: Supplementary data
Journal Articles

Overexpression of hRFI enhances chemoresistance against 5-FU through the inhibition of mitochondrial apoptotic pathway with the up-regulation of Bcl-2 and Bcl-XL in colorectal cancer cells

Shin Sasaki, Toshiaki Watanabe, Tsuyoshi Konishi, Joji Kitayama, Hirokazu Nagawa
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 301.
Published: 15 April 2006
View articletitled, Overexpression of hRFI enhances chemoresistance against 5-FU through the inhibition of mitochondrial apoptotic pathway with the up-regulation of Bcl-2 and Bcl-XL in colorectal cancer cells