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Journal Articles

EGFR and c-MET Cooperate to Enhance Resistance to PARP Inhibitors in Hepatocellular Carcinoma

Qiongzhu Dong, Yi Du, Hui Li, Chunxiao Liu, Yongkun Wei, Mei-Kuang Chen, Xixi Zhao, Yu-Yi Chu, Yufan Qiu, Lunxiu Qin, Hirohito Yamaguchi, Mien-Chie Hung

Cancer Res (2019) 79 (4): 819–829.

DOI: https://doi.org/10.1158/0008-5472.CAN-18-1273

Published: 15 February 2019

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Includes: Supplementary data

Journal Articles

Abstract LB-131: Targeting expression of EZH2 with increased H3K27 trimethylation activity drives and synergizes with oncogene to promote mammary tumorigenesis in genetically engineered mouse models

Lei Nie, Yongkun Wei, Hirohito Yamaguchi, Longfei Huo, Weiya Xia, Rong Deng, Jun Tang, Cihui Zhu, Baozhen Ke, Mien-Chie Hung

Cancer Res (2017) 77 (13_Supplement): LB-131.

DOI: https://doi.org/10.1158/1538-7445.AM2017-LB-131

Published: 01 July 2017

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Journal Articles

AKT1 Inhibits Epithelial-to-Mesenchymal Transition in Breast Cancer through Phosphorylation-Dependent Twist1 Degradation

Cancer Res (2016) 76 (6): 1451–1462.

DOI: https://doi.org/10.1158/0008-5472.CAN-15-1941

Published: 14 March 2016

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Includes: Supplementary data

Journal Articles

Abstract 5120: Using flow-proteometric platform to analyze individual signaling complexes in tumor tissue

Chao-Kai Chou, Heng-Huan Lee, Pei-Hsiang Tsou, Chun-Te Chen, Jung-Mao Hsu, Hirohito Yamaguchi, Ying-Nai Wang, Jennifer L. Hsu, Jin-Fong Lee, Jun Kameoka, Mien-Chie Hung

Cancer Res (2015) 75 (15_Supplement): 5120.

DOI: https://doi.org/10.1158/1538-7445.AM2015-5120

Published: 01 August 2015

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Journal Articles

Abstract 1051: EGFR inhibitors attenuate caspase-independent cell death and confer negative effects on cisplatin .

Hirohito Yamaguchi, Jennifer L. Hsu, Chun-Te Chen, Ying-Nai Wang, Ming-Chuan Hsu, Shih-Shin Chang, Yi Du, How-Wen Ko, Roy S. Herbst, Mien-Chie Hung

Cancer Res (2013) 73 (8_Supplement): 1051.

DOI: https://doi.org/10.1158/1538-7445.AM2013-1051

Published: 15 April 2013

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Journal Articles

Abstract 5169: Flow-proteometric analysis of single signaling complex.

Chao-Kai Chou, Heng-Huan Lee, Pei-Hsiang Tsou, Hirohito Yamaguchi, Ying-Nai Wang, Hong-Jen Lee, Jun Kameoka, Mien-Chie Hung

Cancer Res (2013) 73 (8_Supplement): 5169.

DOI: https://doi.org/10.1158/1538-7445.AM2013-5169

Published: 15 April 2013

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Journal Articles

Abstract 1230: Syntaxin 6- and microtubule-mediated intracellular trafficking contributes to Golgi and nuclear translocation of EGFR

Yi Du, Jia Shen, Jennifer L. Hsu, Zhenbo Han, Ying-Nai Wang, Hirohito Yamaguchi, Stephanie A. Miller, Mien-Chie Hung

Cancer Res (2012) 72 (8_Supplement): 1230.

DOI: https://doi.org/10.1158/1538-7445.AM2012-1230

Published: 15 April 2012

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Journal Articles

Epithelial–Mesenchymal Transition Induced by TNF-α Requires NF-κB–Mediated Transcriptional Upregulation of Twist1

Chia-Wei Li, Weiya Xia, Longfei Huo, Seung-Oe Lim, Yun Wu, Jennifer L. Hsu, Chi-Hong Chao, Hirohito Yamaguchi, Neng-Kai Yang, Qingqing Ding, Yan Wang, Yun-Ju Lai, Adam M. LaBaff, Ting-Jung Wu, Been-Ren Lin, Muh-Hwa Yang, Gabriel N. Hortobagyi, Mien-Chie Hung

Cancer Res (2012) 72 (5): 1290–1300.

DOI: https://doi.org/10.1158/0008-5472.CAN-11-3123

Published: 01 March 2012

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Includes: Supplementary data

Journal Articles

FOXO3a-Dependent Mechanism of E1A-Induced Chemosensitization

Jen-Liang Su, Xiaoyun Cheng, Hirohito Yamaguchi, Yi-Wen Chang, Chao-Feng Hou, Dung-Fang Lee, How-Wen Ko, Kuo-Tai Hua, Ying-Nai Wang, Michael Hsiao, PoShen B. Chen, Jung-Mao Hsu, Robert C. Bast, Jr, Gabriel N. Hortobagyi, Mien-Chie Hung

Cancer Res (2011) 71 (21): 6878–6887.

DOI: https://doi.org/10.1158/0008-5472.CAN-11-0295

Published: 30 October 2011

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Includes: Supplementary data

Journal Articles

Abstract 4051: EGF receptor trafficking from the cell surface to the nucleus through the Golgi, ER, and nuclear envelope

Ying-Nai Wang, Hirohito Yamaguchi, Longfei Huo, Yi Du, Hong-Jen Lee, Heng-Huan Lee, Hongmei Wang, Jung-Mao Hsu, Mien-Chie Hung

Cancer Res (2011) 71 (8_Supplement): 4051.

DOI: https://doi.org/10.1158/1538-7445.AM2011-4051

Published: 15 April 2011

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Journal Articles

Abstract 721: Putative molecular mechanism contributing AZD6244 resistance in lung cancer

Hirohito Yamaguchi, Jennifer Hsu, How-Wen Ko, Ying-Nai Wang, Shih-Shin Chang, Mien-Chie Hung

Cancer Res (2011) 71 (8_Supplement): 721.

DOI: https://doi.org/10.1158/1538-7445.AM2011-721

Published: 15 April 2011

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Journal Articles

Abstract 4017: Identifying Protein-Protein Interactions in Single Protein Complex level by Microchannel Device

Chao-Kai Chou, Nan Jing, Hirohito Yamaguchi, Pei-Hsiang Tsou, Jun Kameoka, Mien-Chie Hung

Cancer Res (2010) 70 (8_Supplement): 4017.

DOI: https://doi.org/10.1158/1538-7445.AM10-4017

Published: 15 April 2010

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Journal Articles

Abstract #3787: A novel hTERT promoter-driven E1A therapeutic for ovarian cancer

Xiaoming Xie, Jennifer Hsu, Min-Gew Choi, Weiya Xia, Hirohito Yamaguchi, Chun-Te Chen, Zhen Lu, Robert Bast, Mien-Chie Hung

Cancer Res (2009) 69 (9_Supplement): 3787.

Published: 01 May 2009

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Journal Articles

Abstract #2784: Targeted BIKDD expression promotes lapatinib efficacy for breast cancer treatment

Jingyu Lang, Jennifer Hsu, Yi Bao, Hirohito Yamaguchi, Xiaoming Xie, Gabriel Hortobagyi, Mien-Chie Hung

Cancer Res (2009) 69 (9_Supplement): 2784.

Published: 01 May 2009

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Journal Articles

Interferon-inducible protein IFIXα induces downregulation of histone deacetylase 1, upregulation of maspin and inhibition of invasion in breast cancer cells.

Hirohito Yamaguchi, Yi Ding, Jin-Fong Lee, Duen-Hwa Yan, Mien-Chie Hung

Cancer Res (2008) 68 (9_Supplement): 5391.

Published: 01 May 2008

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Journal Articles

Nuclear transport of EGFR is through the integral trafficking from the endoplasmic reticulum to the nuclear envelope

Ying-Nai Wang, Hirohito Yamaguchi, Yi Du, Longfei Huo, Jung-Mao Hsu, Hongmei Wang, Mien-Chie Hung

Cancer Res (2008) 68 (9_Supplement): 3501.

Published: 01 May 2008

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Journal Articles

Anoikis, Initiated by Mcl-1 Degradation and Bim Induction, Is Deregulated during Oncogenesis

Nicholas T. Woods, Hirohito Yamaguchi, Francis Y. Lee, Kapil N. Bhalla, Hong-Gang Wang

Cancer Res (2007) 67 (22): 10744–10752.

DOI: https://doi.org/10.1158/0008-5472.CAN-07-3148

Published: 15 November 2007

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Includes: Supplementary data

Journal Articles

Tissue transglutaminase prevents thapsigargin-induced cell death through cross-linking of caspase-3 in Bax-deficient HCT116 cells

Hirohito Yamaguchi, Hong-Gang Wang

Cancer Res (2006) 66 (8_Supplement): 171.

Published: 15 April 2006

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Journal Articles

Silencing of Bif-1 prevents Bax activation and increases tumorigenicity of HeLa cells

Yoshinori Takahashi, Hirohito Yamaguchi, Aslamuzzaman Kazi, Jie Wu, Said M. Sebti, Hong-Gang Wang

Cancer Res (2005) 65 (9_Supplement): 823–824.

Published: 01 May 2005

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Journal Articles

Bax Plays a Pivotal Role in Thapsigargin-induced Apoptosis of Human Colon Cancer HCT116 Cells by Controlling Smac/Diablo and Omi/HtrA2 Release from Mitochondria

Hirohito Yamaguchi, Kapil Bhalla, Hong-Gang Wang

Cancer Res (2003) 63 (7): 1483–1489.

Published: 01 April 2003

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NARROW

EGFR and c-MET Cooperate to Enhance Resistance to PARP Inhibitors in Hepatocellular Carcinoma

Abstract LB-131: Targeting expression of EZH2 with increased H3K27 trimethylation activity drives and synergizes with oncogene to promote mammary tumorigenesis in genetically engineered mouse models

AKT1 Inhibits Epithelial-to-Mesenchymal Transition in Breast Cancer through Phosphorylation-Dependent Twist1 Degradation

Abstract 5120: Using flow-proteometric platform to analyze individual signaling complexes in tumor tissue

Abstract 1051: EGFR inhibitors attenuate caspase-independent cell death and confer negative effects on cisplatin .

Abstract 5169: Flow-proteometric analysis of single signaling complex.

Abstract 1230: Syntaxin 6- and microtubule-mediated intracellular trafficking contributes to Golgi and nuclear translocation of EGFR

Epithelial–Mesenchymal Transition Induced by TNF-α Requires NF-κB–Mediated Transcriptional Upregulation of Twist1

FOXO3a-Dependent Mechanism of E1A-Induced Chemosensitization

Abstract 4051: EGF receptor trafficking from the cell surface to the nucleus through the Golgi, ER, and nuclear envelope

Abstract 721: Putative molecular mechanism contributing AZD6244 resistance in lung cancer

Abstract 4017: Identifying Protein-Protein Interactions in Single Protein Complex level by Microchannel Device

Abstract #3787: A novel hTERT promoter-driven E1A therapeutic for ovarian cancer

Abstract #2784: Targeted BIKDD expression promotes lapatinib efficacy for breast cancer treatment

Interferon-inducible protein IFIXα induces downregulation of histone deacetylase 1, upregulation of maspin and inhibition of invasion in breast cancer cells.

Nuclear transport of EGFR is through the integral trafficking from the endoplasmic reticulum to the nuclear envelope

Anoikis, Initiated by Mcl-1 Degradation and Bim Induction, Is Deregulated during Oncogenesis

Tissue transglutaminase prevents thapsigargin-induced cell death through cross-linking of caspase-3 in Bax-deficient HCT116 cells

Silencing of Bif-1 prevents Bax activation and increases tumorigenicity of HeLa cells

Bax Plays a Pivotal Role in Thapsigargin-induced Apoptosis of Human Colon Cancer HCT116 Cells by Controlling Smac/Diablo and Omi/HtrA2 Release from Mitochondria

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