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Journal Articles

Abstract 2794: Blocking histamine receptor H1 on macrophages with anti-allergy drugs restores T-cell anti-tumor immunity

Hongzhong Li, Yi Xiao, Jun Yao, Xiangliang Yuan, Xuedong Yin, Yuan Zhang, Yohei Saito, Hideo Yagita, Don Gibbons, Dihua Yu

Cancer Res (2021) 81 (13_Supplement): 2794.

https://doi.org/10.1158/1538-7445.AM2021-2794

Published: 01 July 2021

View article titled, Abstract 2794: Blocking histamine receptor H1 on macrophages with anti-allergy drugs restores T-cell anti-tumor immunity

Journal Articles

Abstract 4565: Effective inhibition of metastasis in triple-negative breast cancer (TNBC) mouse model by combining immunogenic chemotherapy and immune checkpoint blockade

Xiangliang Yuan, Yi Xiao, Xianghua Liu, Wenling Kuo, Hongzhong Li, Ping Li, Hideo Yagita, Dihua Yu

Cancer Res (2018) 78 (13_Supplement): 4565.

https://doi.org/10.1158/1538-7445.AM2018-4565

Published: 01 July 2018

View article titled, Abstract 4565: Effective inhibition of metastasis in triple-negative breast cancer (TNBC) mouse model by combining immunogenic chemotherapy and immune checkpoint blockade

Journal Articles

Abstract 1700: Radiation-induced vegf-targeted 4-1bb costimulation enhances immune control of tumor growth

Brett Schrand, Bhavna Verma, Agata Levay, Shradha Patel, Iris Castro, Ana Paula Benaduce, Randall Brenneman, Oliver Umland, Hideo Yagita, Eli Gilboa, Adrian Ishkanian

Cancer Res (2017) 77 (13_Supplement): 1700.

https://doi.org/10.1158/1538-7445.AM2017-1700

Published: 01 July 2017

View article titled, Abstract 1700: Radiation-induced vegf-targeted 4-1bb costimulation enhances immune control of tumor growth

Journal Articles

Radiation-Induced Enhancement of Antitumor T-cell Immunity by VEGF-Targeted 4-1BB Costimulation

Brett Schrand, Bhavna Verma, Agata Levay, Shradha Patel, Iris Castro, Ana Paula Benaduce, Randall Brenneman, Oliver Umland, Hideo Yagita, Eli Gilboa, Adrian Ishkanian

Cancer Res (2017) 77 (6): 1310–1321.

https://doi.org/10.1158/0008-5472.CAN-16-2105

Published: 14 March 2017

View article titled, Radiation-Induced Enhancement of Antitumor T-cell Immunity by VEGF-Targeted 4-1BB Costimulation

Includes: Supplementary data

Journal Articles

Agonistic CD40 mAb-Driven IL12 Reverses Resistance to Anti-PD1 in a T-cell–Rich Tumor

Shin Foong Ngiow, Arabella Young, Stephen J. Blake, Geoffrey R. Hill, Hideo Yagita, Michele W. L. Teng, Alan J. Korman, Mark J. Smyth

Cancer Res (2016) 76 (21): 6266–6277.

https://doi.org/10.1158/0008-5472.CAN-16-2141

Published: 31 October 2016

View article titled, Agonistic CD40 mAb-Driven IL12 Reverses Resistance to Anti-PD1 in a T-cell–Rich Tumor

Includes: Supplementary data

Journal Articles

Tumor Eradication by Cisplatin Is Sustained by CD80/86-Mediated Costimulation of CD8⁺ T Cells

Elham Beyranvand Nejad, Tetje C. van der Sluis, Suzanne van Duikeren, Hideo Yagita, George M. Janssen, Peter A. van Veelen, Cornelis J.M. Melief, Sjoerd H. van der Burg, Ramon Arens

Cancer Res (2016) 76 (20): 6017–6029.

https://doi.org/10.1158/0008-5472.CAN-16-0881

Published: 13 October 2016

View article titled, Tumor Eradication by Cisplatin Is Sustained by CD80/86-Mediated Costimulation of CD8+ T Cells

Includes: Supplementary data

Journal Articles

Systemic DC Activation Modulates the Tumor Microenvironment and Shapes the Long-Lived Tumor-Specific Memory Mediated by CD8⁺ T Cells

Kanako Shimizu, Satoru Yamasaki, Jun Shinga, Yusuke Sato, Takashi Watanabe, Osamu Ohara, Kiyotaka Kuzushima, Hideo Yagita, Yoshiko Komuro, Miki Asakura, Shin-ichiro Fujii

Cancer Res (2016) 76 (13): 3756–3766.

https://doi.org/10.1158/0008-5472.CAN-15-3219

Published: 30 June 2016

View article titled, Systemic DC Activation Modulates the Tumor Microenvironment and Shapes the Long-Lived Tumor-Specific Memory Mediated by CD8+ T Cells

Includes: Supplementary data

Journal Articles

CD27 Agonism Plus PD-1 Blockade Recapitulates CD4⁺ T-cell Help in Therapeutic Anticancer Vaccination

Tomasz Ahrends, Nikolina Bąbała, Yanling Xiao, Hideo Yagita, Hans van Eenennaam, Jannie Borst

Cancer Res (2016) 76 (10): 2921–2931.

https://doi.org/10.1158/0008-5472.CAN-15-3130

Published: 12 May 2016

View article titled, CD27 Agonism Plus PD-1 Blockade Recapitulates CD4+ T-cell Help in Therapeutic Anticancer Vaccination

Includes: Supplementary data

Journal Articles

Agonists of the TRAIL Death Receptor DR5 Sensitize Intestinal Stem Cells to Chemotherapy-Induced Cell Death and Trigger Gastrointestinal Toxicity

Niklas K. Finnberg, Prashanth Gokare, Arunasalam Navaraj, Krystle A. Lang Kuhs, George Cerniglia, Hideo Yagita, Kazuyoshi Takeda, Noboru Motoyama, Wafik S. El-Deiry

Cancer Res (2016) 76 (3): 700–712.

https://doi.org/10.1158/0008-5472.CAN-15-2759

Published: 31 January 2016

View article titled, Agonists of the TRAIL Death Receptor DR5 Sensitize Intestinal Stem Cells to Chemotherapy-Induced Cell Death and Trigger Gastrointestinal Toxicity

Includes: Supplementary data

Journal Articles

Bortezomib Improves Adoptive T-cell Therapy by Sensitizing Cancer Cells to FasL Cytotoxicity

Anil Shanker, Samuel T. Pellom, Jr, Duafalia F. Dudimah, Menaka C. Thounaojam, Rachel L. de Kluyver, Alan D. Brooks, Hideo Yagita, Daniel W. McVicar, William J. Murphy, Dan L. Longo, Thomas J. Sayers

Cancer Res (2015) 75 (24): 5260–5272.

https://doi.org/10.1158/0008-5472.CAN-15-0794

Published: 14 December 2015

View article titled, Bortezomib Improves Adoptive T-cell Therapy by Sensitizing Cancer Cells to FasL Cytotoxicity

Includes: Supplementary data

Journal Articles

Abstract 3289: Skeletal consequences of bone resorption inhibitors (zoledronic acid and RANKL blocking antibody) injections during growth: mouse strain disparities and synergic effect

Frederic P. Lezot, Benjamin Navet, YongWon Choi, Hideo Yagita, Ariane Berdal, Christopher G. Mueller, Francoise Redini, Dominique Heymann

Cancer Res (2015) 75 (15_Supplement): 3289.

https://doi.org/10.1158/1538-7445.AM2015-3289

Published: 01 August 2015

View article titled, Abstract 3289: Skeletal consequences of bone resorption inhibitors (zoledronic acid and RANKL blocking antibody) injections during growth: mouse strain disparities and synergic effect

Journal Articles

Abstract 1439: RANK expression by osteosarcoma cells increases lung metastasis in Nude mouse while has no effect in immune-competent mouse

Benjamin Navet, Kosei Ando, Hideo Yagita, Christopher G. Mueller, Dominique Heymann, Frederic Lezot

Cancer Res (2015) 75 (15_Supplement): 1439.

https://doi.org/10.1158/1538-7445.AM2015-1439

Published: 01 August 2015

View article titled, Abstract 1439: RANK expression by osteosarcoma cells increases lung metastasis in Nude mouse while has no effect in immune-competent mouse

Journal Articles

Abstract 2926: DR5-targeting sensitizes Lgr5+ stem cells to p53 and Chk2-dependent chemotherapy-induced cell death and produces dose-limiting gastrointestinal toxicity (GIT)

Niklas K. Finnberg, Prashanth Gokare, Arunasalam Navaraj, Krystle A. Lang Kuhs, George Cerniglia, Hideo Yagita, Kazuyoshi Takeda, Noboru Motoyama, Wafik S. El-Deiry

Cancer Res (2015) 75 (15_Supplement): 2926.

https://doi.org/10.1158/1538-7445.AM2015-2926

Published: 01 August 2015

View article titled, Abstract 2926: DR5-targeting sensitizes Lgr5+ stem cells to p53 and Chk2-dependent chemotherapy-induced cell death and produces dose-limiting gastrointestinal toxicity (GIT)

Journal Articles

Abstract B1: Radiotherapy promotes tumor-specific effector CD8+ T cells via DC activation.

Anurag K. Gupta, Hans Christian Probst, Van Vuong, Alexandro Landshammer, Sabine Muth, Hideo Yagita, Reto Schwendener, Martin Pruschy, Alexander Knuth, Maries van den Broek

Cancer Res (2013) 73 (1_Supplement): B1.

https://doi.org/10.1158/1538-7445.TUMIMM2012-B1

Published: 02 April 2014

View article titled, Abstract B1: Radiotherapy promotes tumor-specific effector CD8+ T cells via DC activation.

Journal Articles

Abstract A18: Mouse models of autochthonous cancer to study local immune subversion.

Ali Bransi, Hideo Yagita, Alexander Knuth, Maries van den Broek

Cancer Res (2013) 73 (1_Supplement): A18.

https://doi.org/10.1158/1538-7445.TUMIMM2012-A18

Published: 02 April 2014

View article titled, Abstract A18: Mouse models of autochthonous cancer to study local immune subversion.

Journal Articles

Antitumor Activity of a Humanized, Bivalent Immunotoxin Targeting Fn14-Positive Solid Tumors

Hong Zhou, Walter N. Hittelman, Hideo Yagita, Lawrence H. Cheung, Stuart S. Martin, Jeffrey A. Winkles, Michael G. Rosenblum

Cancer Res (2013) 73 (14): 4439–4450.

https://doi.org/10.1158/0008-5472.CAN-13-0187

Published: 15 July 2013

View article titled, Antitumor Activity of a Humanized, Bivalent Immunotoxin Targeting Fn14-Positive Solid Tumors

Includes: Supplementary data

Journal Articles

Bone Marrow–Derived CD11b⁺Jagged2⁺ Cells Promote Epithelial-to-Mesenchymal Transition and Metastasization in Colorectal Cancer

Francisco Caiado, Tânia Carvalho, Isadora Rosa, Leonor Remédio, Ana Costa, João Matos, Beate Heissig, Hideo Yagita, Koichi Hattori, João Pereira da Silva, Paulo Fidalgo, António Dias Pereira, Sérgio Dias

Cancer Res (2013) 73 (14): 4233–4246.

https://doi.org/10.1158/0008-5472.CAN-13-0085

Published: 15 July 2013

View article titled, Bone Marrow–Derived CD11b+Jagged2+ Cells Promote Epithelial-to-Mesenchymal Transition and Metastasization in Colorectal Cancer

Includes: Supplementary data

Journal Articles

Durable Adoptive Immunotherapy for Leukemia Produced by Manipulation of Multiple Regulatory Pathways of CD8⁺ T-Cell Tolerance

Melissa M. Berrien-Elliott, Stephanie R. Jackson, Jennifer M. Meyer, Craig J. Rouskey, Thanh-Long M. Nguyen, Hideo Yagita, Philip D. Greenberg, Richard J. DiPaolo, Ryan M. Teague

Cancer Res (2013) 73 (2): 605–616.

https://doi.org/10.1158/0008-5472.CAN-12-2179

Published: 16 January 2013

View article titled, Durable Adoptive Immunotherapy for Leukemia Produced by Manipulation of Multiple Regulatory Pathways of CD8+ T-Cell Tolerance

Includes: Supplementary data

Journal Articles

PD-1 Blockade Enhances T-cell Migration to Tumors by Elevating IFN-γ Inducible Chemokines

Weiyi Peng, Chengwen Liu, Chunyu Xu, Yanyan Lou, Jieqing Chen, Yan Yang, Hideo Yagita, Willem W. Overwijk, Gregory Lizée, Laszlo Radvanyi, Patrick Hwu

Cancer Res (2012) 72 (20): 5209–5218.

https://doi.org/10.1158/0008-5472.CAN-12-1187

Published: 14 October 2012

View article titled, PD-1 Blockade Enhances T-cell Migration to Tumors by Elevating IFN-γ Inducible Chemokines

Includes: Supplementary data

Journal Articles

Radiotherapy Increases the Permissiveness of Established Mammary Tumors to Rejection by Immunomodulatory Antibodies

Inge Verbrugge, Jim Hagekyriakou, Leslie L. Sharp, Mara Galli, Alison West, Nicole M. McLaughlin, Hélène Duret, Hideo Yagita, Ricky W. Johnstone, Mark J. Smyth, Nicole M. Haynes

Cancer Res (2012) 72 (13): 3163–3174.

https://doi.org/10.1158/0008-5472.CAN-12-0210

Published: 01 July 2012

View article titled, Radiotherapy Increases the Permissiveness of Established Mammary Tumors to Rejection by Immunomodulatory Antibodies

Includes: Supplementary data

NARROW

Abstract 2794: Blocking histamine receptor H1 on macrophages with anti-allergy drugs restores T-cell anti-tumor immunity

Abstract 4565: Effective inhibition of metastasis in triple-negative breast cancer (TNBC) mouse model by combining immunogenic chemotherapy and immune checkpoint blockade

Abstract 1700: Radiation-induced vegf-targeted 4-1bb costimulation enhances immune control of tumor growth

Radiation-Induced Enhancement of Antitumor T-cell Immunity by VEGF-Targeted 4-1BB Costimulation

Agonistic CD40 mAb-Driven IL12 Reverses Resistance to Anti-PD1 in a T-cell–Rich Tumor

Tumor Eradication by Cisplatin Is Sustained by CD80/86-Mediated Costimulation of CD8⁺ T Cells

Systemic DC Activation Modulates the Tumor Microenvironment and Shapes the Long-Lived Tumor-Specific Memory Mediated by CD8⁺ T Cells

CD27 Agonism Plus PD-1 Blockade Recapitulates CD4⁺ T-cell Help in Therapeutic Anticancer Vaccination

Agonists of the TRAIL Death Receptor DR5 Sensitize Intestinal Stem Cells to Chemotherapy-Induced Cell Death and Trigger Gastrointestinal Toxicity

Bortezomib Improves Adoptive T-cell Therapy by Sensitizing Cancer Cells to FasL Cytotoxicity

Abstract 3289: Skeletal consequences of bone resorption inhibitors (zoledronic acid and RANKL blocking antibody) injections during growth: mouse strain disparities and synergic effect

Abstract 1439: RANK expression by osteosarcoma cells increases lung metastasis in Nude mouse while has no effect in immune-competent mouse

Abstract 2926: DR5-targeting sensitizes Lgr5+ stem cells to p53 and Chk2-dependent chemotherapy-induced cell death and produces dose-limiting gastrointestinal toxicity (GIT)

Abstract B1: Radiotherapy promotes tumor-specific effector CD8+ T cells via DC activation.

Abstract A18: Mouse models of autochthonous cancer to study local immune subversion.

Antitumor Activity of a Humanized, Bivalent Immunotoxin Targeting Fn14-Positive Solid Tumors

Bone Marrow–Derived CD11b⁺Jagged2⁺ Cells Promote Epithelial-to-Mesenchymal Transition and Metastasization in Colorectal Cancer

Durable Adoptive Immunotherapy for Leukemia Produced by Manipulation of Multiple Regulatory Pathways of CD8⁺ T-Cell Tolerance

PD-1 Blockade Enhances T-cell Migration to Tumors by Elevating IFN-γ Inducible Chemokines

Radiotherapy Increases the Permissiveness of Established Mammary Tumors to Rejection by Immunomodulatory Antibodies

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