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Mathematical Modeling and Mutational Analysis Reveal Optimal Therapy to Prevent Malignant Transformation in Grade II IDH-Mutant Gliomas

Cancer Res (2021) 81 (18): 4861–4873.

https://doi.org/10.1158/0008-5472.CAN-21-0985

Published: 15 September 2021

View articletitled, Mathematical Modeling and Mutational Analysis Reveal Optimal Therapy to Prevent Malignant Transformation in Grade II IDH-Mutant Gliomas

Includes: Supplementary data

Journal Articles

Abstract 4751: Genetic subtype-specific prognostic significance of genetic alterations in lower-grade gliomas

Kosuke Aoki, Hiromichi Suzuki, Hideo Nakamura, Keitaro Matsuo, Kazuya Motomura, Fumiharu Ohka, Masahiro Mizoguchi, Yasutomo Momii, Yasuhiro Muragaki, Satoru Miyano, Toshihiko Wakabayashi, Atsushi Natsume, Seishi Ogawa

Cancer Res (2016) 76 (14_Supplement): 4751.

https://doi.org/10.1158/1538-7445.AM2016-4751

Published: 15 July 2016

View articletitled, Abstract 4751: Genetic subtype-specific prognostic significance of genetic alterations in lower-grade gliomas

Journal Articles

Abstract 4791: Prognostic model of lower grade gliomas

Kosuke Aoki, Hiromichi Suzuki, Hideo Nakamura, Masahiro Mizoguchi, Tetsuya Abe, Satoru Miyano, Ichiro Takeuchi, Toshihiko Wakabayashi, Seishi Ogawa, Atsushi Natsume

Cancer Res (2015) 75 (15_Supplement): 4791.

https://doi.org/10.1158/1538-7445.AM2015-4791

Published: 01 August 2015

View articletitled, Abstract 4791: Prognostic model of lower grade gliomas

Journal Articles

Abstract PR04: Novel somatic and germline mutations in intracranial germ cell tumors

Linghua Wang, Shigeru Yamaguchi, Keita Terashima, Mathew D. Burstein, Hideo Nakamura, Tomonari Susuki, Ryo Nishikawa, Atsushi Natsume, Shunsuke Terasaka, Ho Keung Ng, Adekunle Adesina, Richard Gibbs, David Wheeler, Ching Lau

Cancer Res (2014) 74 (20_Supplement): PR04.

https://doi.org/10.1158/1538-7445.PEDCAN-PR04

Published: 09 October 2014

View articletitled, Abstract PR04: Novel somatic and germline mutations in intracranial germ cell tumors

Journal Articles

Abstract LB-355: Whole-exome sequencing of intracranial germ cell tumors reveals frequent mutations in KIT and RAS pathways and histone demethylases.

Linghua Wang, Shigeru Yamaguchi, Keita Terashima, Matthew D. Burstein, Jiayi M. Sun, Tomonari Suzuki, Ryo Nishikawa, Hideo Nakamura, Atsushi Natsume, Shunsuke Terasaka, Ho-Keung Ng, Robert C. Dauser, William E. Whitehead, Adesina M. Adekunle, Donna M. Muzny, Richard A. Gibbs, Ching C. Lau, David A. Wheeler

Cancer Res (2013) 73 (8_Supplement): LB-355.

https://doi.org/10.1158/1538-7445.AM2013-LB-355

Published: 15 April 2013

View articletitled, Abstract LB-355: Whole-exome sequencing of intracranial germ cell tumors reveals frequent mutations in KIT and RAS pathways and histone demethylases.

Journal Articles

Abstract 1144: Micro RNA profiling of intracranial germ cell tumors

Keita Terashima, Jianhe J. Shen, Joseph Luan, Alexander Yu, Tomonari Suzuki, Ryo Nishikawa, Masao Matsutani, Hideo Nakamura, Sayano Kinjo, Atsushi Natsume, Toshihiko Wakabayashi, Jeffrey C. Allen, Kenneth D. Aldape, Adekunle M. Adesina, Tsz-Kwong Man, Ching C. Lau

Cancer Res (2011) 71 (8_Supplement): 1144.

https://doi.org/10.1158/1538-7445.AM2011-1144

Published: 15 April 2011

View articletitled, Abstract 1144: Micro RNA profiling of intracranial germ cell tumors

Journal Articles

NKX2.2 Suppresses Self-Renewal of Glioma-Initiating Cells

Teruyuki Muraguchi, Shingo Tanaka, Daisuke Yamada, Akira Tamase, Mitsutoshi Nakada, Hideo Nakamura, Takayuki Hoshii, Takako Ooshio, Yuko Tadokoro, Kazuhito Naka, Yasushi Ino, Tomoki Todo, Jun-ichi Kuratsu, Hideyuki Saya, Jun-ichiro Hamada, Atsushi Hirao

Cancer Res (2011) 71 (3): 1135–1145.

https://doi.org/10.1158/0008-5472.CAN-10-2304

Published: 01 February 2011

View articletitled, NKX2.2 Suppresses Self-Renewal of Glioma-Initiating Cells

Includes: Supplementary data

Journal Articles

Sox11 Prevents Tumorigenesis of Glioma-Initiating Cells by Inducing Neuronal Differentiation

Takuichiro Hide, Tatsuya Takezaki, Yuka Nakatani, Hideo Nakamura, Jun-ichi Kuratsu, Toru Kondo

Cancer Res (2009) 69 (20): 7953–7959.

https://doi.org/10.1158/0008-5472.CAN-09-2006

Published: 14 October 2009

View articletitled, Sox11 Prevents Tumorigenesis of Glioma-Initiating Cells by Inducing Neuronal Differentiation

Includes: Supplementary data

Journal Articles

The functional role of eIF-4E in primary central nervous system lymphoma

Daisuke Muta, Keishi Makino, Hideo Nakamura, Jun-ichi Kuratsu

Cancer Res (2008) 68 (9_Supplement): 3418.

Published: 01 May 2008

View articletitled, The functional role of eIF-4E in primary central nervous system lymphoma

Journal Articles

17DMAG inhibits NFkB activity in tumors in mice monitored by bioluminescence imaging

Tsuyoshi Suzuki, Junichi Ohya, Hideo Nakamura

Cancer Res (2007) 67 (9_Supplement): 5729.

Published: 01 May 2007

View articletitled, 17DMAG inhibits NFkB activity in tumors in mice monitored by bioluminescence imaging

Journal Articles

MP-412, a dual EGFR/HER2 tyrosine kinase inhibitor shows antitumor activity against both Erlotinib/Gefitinib-sensitive and resistant EGFR mutations in human lung cancer xenograft models

Akihiro Fujii, Tsuyoshi Suzuki, Jun-Ichi Ohya, Hideo Nakamura

Cancer Res (2006) 66 (8_Supplement): 949–950.

Published: 15 April 2006

View articletitled, MP-412, a dual EGFR/HER2 tyrosine kinase inhibitor shows antitumor activity against both Erlotinib/Gefitinib-sensitive and resistant EGFR mutations in human lung cancer xenograft models

Journal Articles

MP-412, a dual EGFR/HER2 tyrosine kinase inhibitor: 2. In vivo antitumor effects

Akihiro Fujii, Tsuyoshi Suzuki, Jun-Ichi Ohya, Hideo Nakamura, Fumiko Fujita, Michiko Koike, Takashi Aburano, Masahide Fujita

Cancer Res (2005) 65 (9_Supplement): 800.

Published: 01 May 2005

View articletitled, MP-412, a dual EGFR/HER2 tyrosine kinase inhibitor: 2. In vivo antitumor effects

Journal Articles

MP-412, a dual EGFR/HER2 tyrosine kinase inhibitor: 1. In vitro kinase inhibition profile

Tsuyoshi Suzuki, Akihiro Fujii, Yusaku Amano, Yasunori Kitano, Daisuke Abe, Hideo Nakamura

Cancer Res (2005) 65 (9_Supplement): 802.

Published: 01 May 2005

View articletitled, MP-412, a dual EGFR/HER2 tyrosine kinase inhibitor: 1. In vitro kinase inhibition profile

Journal Articles

Selectivity of an Oncolytic Herpes Simplex Virus for Cells Expressing the DF3/MUC1 Antigen

Hideki Kasuya, Timothy M. Pawlik, John T. Mullen, James M. Donahue, Hideo Nakamura, Soundararajalu Chandrasekhar, Hiroshi Kawasaki, Enid Choi, Kenneth K. Tanabe

Cancer Res (2004) 64 (7): 2561–2567.

https://doi.org/10.1158/0008-5472.CAN-03-3431

Published: 01 April 2004

View articletitled, Selectivity of an Oncolytic Herpes Simplex Virus for Cells Expressing the DF3/MUC1 Antigen

Journal Articles

Prognostic Value of Epidermal Growth Factor Receptor in Patients with Glioblastoma Multiforme

Naoki Shinojima, Kenji Tada, Shoji Shiraishi, Takanori Kamiryo, Masato Kochi, Hideo Nakamura, Keishi Makino, Hideyuki Saya, Hirofumi Hirano, Jun-ichi Kuratsu, Koji Oka, Yasuji Ishimaru, Yukitaka Ushio

Cancer Res (2003) 63 (20): 6962–6970.

Published: 28 October 2003

View articletitled, Prognostic Value of Epidermal Growth Factor Receptor in Patients with Glioblastoma Multiforme

Journal Articles

Multimodality Therapy with a Replication-conditional Herpes Simplex Virus 1 Mutant that Expresses Yeast Cytosine Deaminase for Intratumoral Conversion of 5-Fluorocytosine to 5-Fluorouracil

Hideo Nakamura, John T. Mullen, Soundararajalu Chandrasekhar, Timothy M. Pawlik, Sam S. Yoon, Kenneth K. Tanabe

Cancer Res (2001) 61 (14): 5447–5452.

Published: 01 July 2001

View articletitled, Multimodality Therapy with a Replication-conditional Herpes Simplex Virus 1 Mutant that Expresses Yeast Cytosine Deaminase for Intratumoral Conversion of 5-Fluorocytosine to 5-Fluorouracil

Journal Articles

Oncolysis of Diffuse Hepatocellular Carcinoma by Intravascular Administration of a Replication-competent, Genetically Engineered Herpesvirus

Timothy M. Pawlik, Hideo Nakamura, Sam S. Yoon, John T. Mullen, Soundararajalu Chandrasekhar, E. Antonio Chiocca, Kenneth K. Tanabe

Cancer Res (2000) 60 (11): 2790–2795.

Published: 01 June 2000

View articletitled, Oncolysis of Diffuse Hepatocellular Carcinoma by Intravascular Administration of a Replication-competent, Genetically Engineered Herpesvirus

Journal Articles

Mouse Endostatin Inhibits the Formation of Lung and Liver Metastases

Sam S. Yoon, Hiroshi Eto, Cheng-mao Lin, Hideo Nakamura, Timothy M. Pawlik, Sun U. Song, Kenneth K. Tanabe

Cancer Res (1999) 59 (24): 6251–6256.

Published: 15 December 1999

View articletitled, Mouse Endostatin Inhibits the Formation of Lung and Liver Metastases

Journal Articles

A Novel Hydrophobized Polysaccharide/Oncoprotein Complex Vaccine Induces in Vitro and in Vivo Cellular and Humoral Immune Responses against HER2-expressing Murine Sarcomas

Xiao-Gang Gu, Michael Schmitt, Atsunori Hiasa, Yasuhiro Nagata, Hiroaki Ikeda, Yoshihiro Sasaki, Kazunari Akiyoshi, Junzo Sunamoto, Hideo Nakamura, Kagemasa Kuribayashi, Hiroshi Shiku

Cancer Res (1998) 58 (15): 3385–3390.

Published: 01 August 1998

View articletitled, A Novel Hydrophobized Polysaccharide/Oncoprotein Complex Vaccine Induces in Vitro and in Vivo Cellular and Humoral Immune Responses against HER2-expressing Murine Sarcomas

Journal Articles

Development of Adult T-Cell Leukemia-like Disease in African Green Monkey Associated with Clonal Integration of Simian T-Cell Leukemia Virus Type I

Hajime Tsujimoto, Yoshihiro Noda, Koh-ichi Ishikawa, Hideo Nakamura, Masashi Fukasawa, Ippei Sakakibara, Akira Sasagawa, Shigeo Honjo, Masanori Hayami

Cancer Res (1987) 47 (1): 269–274.

Published: 01 January 1987

View articletitled, Development of Adult T-Cell Leukemia-like Disease in African Green Monkey Associated with Clonal Integration of Simian T-Cell Leukemia Virus Type I

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Mathematical Modeling and Mutational Analysis Reveal Optimal Therapy to Prevent Malignant Transformation in Grade II IDH-Mutant Gliomas

Abstract 4751: Genetic subtype-specific prognostic significance of genetic alterations in lower-grade gliomas

Abstract 4791: Prognostic model of lower grade gliomas

Abstract PR04: Novel somatic and germline mutations in intracranial germ cell tumors

Abstract LB-355: Whole-exome sequencing of intracranial germ cell tumors reveals frequent mutations in KIT and RAS pathways and histone demethylases.

Abstract 1144: Micro RNA profiling of intracranial germ cell tumors

NKX2.2 Suppresses Self-Renewal of Glioma-Initiating Cells

Sox11 Prevents Tumorigenesis of Glioma-Initiating Cells by Inducing Neuronal Differentiation

The functional role of eIF-4E in primary central nervous system lymphoma

17DMAG inhibits NFkB activity in tumors in mice monitored by bioluminescence imaging

MP-412, a dual EGFR/HER2 tyrosine kinase inhibitor shows antitumor activity against both Erlotinib/Gefitinib-sensitive and resistant EGFR mutations in human lung cancer xenograft models

MP-412, a dual EGFR/HER2 tyrosine kinase inhibitor: 2. In vivo antitumor effects

MP-412, a dual EGFR/HER2 tyrosine kinase inhibitor: 1. In vitro kinase inhibition profile

Selectivity of an Oncolytic Herpes Simplex Virus for Cells Expressing the DF3/MUC1 Antigen

Prognostic Value of Epidermal Growth Factor Receptor in Patients with Glioblastoma Multiforme

Multimodality Therapy with a Replication-conditional Herpes Simplex Virus 1 Mutant that Expresses Yeast Cytosine Deaminase for Intratumoral Conversion of 5-Fluorocytosine to 5-Fluorouracil

Oncolysis of Diffuse Hepatocellular Carcinoma by Intravascular Administration of a Replication-competent, Genetically Engineered Herpesvirus

Mouse Endostatin Inhibits the Formation of Lung and Liver Metastases

A Novel Hydrophobized Polysaccharide/Oncoprotein Complex Vaccine Induces in Vitro and in Vivo Cellular and Humoral Immune Responses against HER2-expressing Murine Sarcomas

Development of Adult T-Cell Leukemia-like Disease in African Green Monkey Associated with Clonal Integration of Simian T-Cell Leukemia Virus Type I

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