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Hexin Chen
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Journal Articles

Abstract 3784: miR-489 induces apoptosis and immunogenic cell death through targeting FOXM1 in triple negative breast cancer cells

Gourab Gupta, Ryan Titus, Yogin Patel, Shakthika Sarvanan, Hexin Chen
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3784.
https://doi.org/10.1158/1538-7445.AM2023-3784
Published: 04 April 2023
View articletitled, Abstract 3784: miR-489 induces apoptosis and immunogenic cell death through targeting FOXM1 in triple negative breast cancer cells
Journal Articles

HER2 Overexpression Triggers an IL1α Proinflammatory Circuit to Drive Tumorigenesis and Promote Chemotherapy Resistance

Shou Liu, Ji Shin Lee, Chunfa Jie, Min Ho Park, Yoichiro Iwakura, Yogin Patel, Mithil Soni, David Reisman, Hexin Chen
Journal: Cancer Research
Cancer Res (2018) 78 (8): 2040–2051.
https://doi.org/10.1158/0008-5472.CAN-17-2761
Published: 12 April 2018
View articletitled, HER2 Overexpression Triggers an IL1α Proinflammatory Circuit to Drive Tumorigenesis and Promote Chemotherapy Resistance
Open the PDF for HER2 Overexpression Triggers an IL1α Proinflammatory Circuit to Drive Tumorigenesis and Promote Chemotherapy Resistance in another window
Includes: Supplementary data
Journal Articles

Abstract 2885: Activation of IL1α signaling by HER2 overexpression promotes breast cancer stem cells

Shou Liu, Ji shin Lee, Hexin Chen
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2885.
https://doi.org/10.1158/1538-7445.AM2017-2885
Published: 01 July 2017
View articletitled, Abstract 2885: Activation of IL1α signaling by HER2 overexpression promotes breast cancer stem cells
Journal Articles

Abstract 3424: Role of miR-489 in mammary gland development and Her2 mediated tumorigenesis

Yogin Patel, Mithil Soni, Shou Liu, Hexin Chen
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3424.
https://doi.org/10.1158/1538-7445.AM2017-3424
Published: 01 July 2017
View articletitled, Abstract 3424: Role of miR-489 in mammary gland development and Her2 mediated tumorigenesis
Journal Articles

Abstract 3120: miR-489 function as tumor suppressor miRNA by targeting HER2 in HER2-positive breast cancer

Yogin Patel, Nirav Shah, Racheal Botbyl, Jishin Lee, Hexin Chen
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3120.
https://doi.org/10.1158/1538-7445.AM2015-3120
Published: 01 August 2015
View articletitled, Abstract 3120: miR-489 function as tumor suppressor miRNA by targeting HER2 in HER2-positive breast cancer
Journal Articles

HOXB7 Promotes Malignant Progression by Activating the TGFβ Signaling Pathway

Shou Liu, Kideok Jin, Yvonne Hui, Jie Fu, Chunfa Jie, Sheng Feng, David Reisman, Qian Wang, Daping Fan, Saraswati Sukumar, Hexin Chen
Journal: Cancer Research
Cancer Res (2015) 75 (4): 709–719.
https://doi.org/10.1158/0008-5472.CAN-14-3100
Published: 15 February 2015
View articletitled, HOXB7 Promotes Malignant Progression by Activating the TGFβ Signaling Pathway
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Includes: Supplementary data
Journal Articles

Abstract LB-54: HOXB7 regulates breast cancer stem cells via induction of TGFβ2

Shou Liu, Sarah Johnson, Hexin Chen
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-54.
https://doi.org/10.1158/1538-7445.AM2014-LB-54
Published: 01 October 2014
View articletitled, Abstract LB-54: HOXB7 regulates breast cancer stem cells via induction of TGFβ2
Journal Articles

Abstract 3104: HOXB7 promotes tumor progression via activation of the transformation growth factor-β signaling pathway.

Shou Liu, Hongmei Zhang, Hexin Chen
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3104.
https://doi.org/10.1158/1538-7445.AM2013-3104
Published: 15 April 2013
View articletitled, Abstract 3104: HOXB7 promotes tumor progression via activation of the transformation growth factor-β signaling pathway.
Journal Articles

Abstract 5347: Identification of differentially expressed proteins in breast cancer stem cells using proteomic profiling

Deepak P. Kanojia, Weidong Zhou, Jiajia Zhang, Pang-Kuo Lo, Jun Zhou, Hexin Chen
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5347.
https://doi.org/10.1158/1538-7445.AM2012-5347
Published: 15 April 2012
View articletitled, Abstract 5347: Identification of differentially expressed proteins in breast cancer stem cells using proteomic profiling
Journal Articles

Abstract LB-203: Mathematical modeling of the dynamic interaction between cancers stem cells and non-stem cancer cells and its potential clinical implication

Xinfeng Liu, Deepak Kanojia, Pang-Kuo Lo, Hexin Chen
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-203.
https://doi.org/10.1158/1538-7445.AM2012-LB-203
Published: 15 April 2012
View articletitled, Abstract LB-203: Mathematical modeling of the dynamic interaction between cancers stem cells and non-stem cancer cells and its potential clinical implication
Journal Articles

Abstract 2194: KLF4 overexpression and apigenin treatment inhibited cell migration and induced apoptosis in human malignant neuroblastoma SK-N-DZ and IMR32 cells

Nishant Mohan, Walden Ai, Feng Yu, Hexin Chen, Naren L. Banik, Swapan K. Ray
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2194.
https://doi.org/10.1158/1538-7445.AM2012-2194
Published: 15 April 2012
View articletitled, Abstract 2194: KLF4 overexpression and apigenin treatment inhibited cell migration and induced apoptosis in human malignant neuroblastoma SK-N-DZ and IMR32 cells
Journal Articles

Abstract 4519: In vitro cell and in vivo animal studies of the demethylating agent in treating HER2-amplified breast cancer

Pang-Kuo Lo, Deepak Kanojia, Hexin Chen
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4519.
https://doi.org/10.1158/1538-7445.AM2011-4519
Published: 15 April 2011
View articletitled, Abstract 4519: In vitro cell and in vivo animal studies of the demethylating agent in treating HER2-amplified breast cancer
Journal Articles

Oncogenic Wip1 Phosphatase Is Inhibited by miR-16 in the DNA Damage Signaling Pathway

Xinna Zhang, Guohui Wan, Sizolwenkosi Mlotshwa, Vicki Vance, Franklin G. Berger, Hexin Chen, Xiongbin Lu
Journal: Cancer Research
Cancer Res (2010) 70 (18): 7176–7186.
https://doi.org/10.1158/0008-5472.CAN-10-0697
Published: 14 September 2010
View articletitled, Oncogenic Wip1 Phosphatase Is Inhibited by miR-16 in the DNA Damage Signaling Pathway
Open the PDF for Oncogenic Wip1 Phosphatase Is Inhibited by miR-16 in the DNA Damage Signaling Pathway in another window
Includes: Supplementary data
Journal Articles

Hoxb7 Inhibits Transgenic HER-2/neu–Induced Mouse Mammary Tumor Onset but Promotes Progression and Lung Metastasis

Hexin Chen, Ji Shin Lee, Xiaohui Liang, Huiping Zhang, Tao Zhu, Zhe Zhang, M. Evangeline Taylor, Cynthia Zahnow, Lionel Feigenbaum, Alan Rein, Saraswati Sukumar
Journal: Cancer Research
Cancer Res (2008) 68 (10): 3637–3644.
https://doi.org/10.1158/0008-5472.CAN-07-2926
Published: 15 May 2008
View articletitled, Hoxb7 Inhibits Transgenic HER-2/neu–Induced Mouse Mammary Tumor Onset but Promotes Progression and Lung Metastasis
Open the PDF for Hoxb7 Inhibits Transgenic HER-2/neu–Induced Mouse Mammary Tumor Onset but Promotes Progression and Lung Metastasis in another window
Includes: Supplementary data
Journal Articles

Hoxb7 inhibits transgenic HER2/neu-induced mouse mammary tumor onset but promotes progression and lung metastasis

Hexin Chen, Ji shin Lee, Xiaohui Liang, Huiping Zhang, Cynthia Zahnow, Alan Rein, Saraswati Sukumar
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 126.
Published: 01 May 2008
View articletitled, Hoxb7 inhibits transgenic HER2/neu-induced mouse mammary tumor onset but promotes progression and lung metastasis
Journal Articles

HOXA5 Acts Directly Downstream of Retinoic Acid Receptor β and Contributes to Retinoic Acid–Induced Apoptosis and Growth Inhibition

Hexin Chen, Huiping Zhang, Jishin Lee, Xiaohui Liang, Xinyan Wu, Tao Zhu, Pang-kuo Lo, Xiaokun Zhang, Saraswati Sukumar
Journal: Cancer Research
Cancer Res (2007) 67 (17): 8007–8013.
https://doi.org/10.1158/0008-5472.CAN-07-1405
Published: 05 September 2007
View articletitled, HOXA5 Acts Directly Downstream of Retinoic Acid Receptor β and Contributes to Retinoic Acid–Induced Apoptosis and Growth Inhibition
Open the PDF for HOXA5 Acts Directly Downstream of Retinoic Acid Receptor β and Contributes to Retinoic Acid–Induced Apoptosis and Growth Inhibition in another window
Journal Articles

A Role for the HOXB7 Homeodomain Protein in DNA Repair

Ethel Rubin, Xinyan Wu, Tao Zhu, Joyce C.Y. Cheung, Hexin Chen, Annaka Lorincz, Raj K. Pandita, Girdhar G. Sharma, Hyo Chol Ha, Judith Gasson, Les A. Hanakahi, Tej K. Pandita, Saraswati Sukumar
Journal: Cancer Research
Cancer Res (2007) 67 (4): 1527–1535.
https://doi.org/10.1158/0008-5472.CAN-06-4283
Published: 16 February 2007
View articletitled, A Role for the HOXB7 Homeodomain Protein in DNA Repair
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Journal Articles

HOXB7, a Homeodomain Protein, Is Overexpressed in Breast Cancer and Confers Epithelial-Mesenchymal Transition

Xinyan Wu, Hexin Chen, Belinda Parker, Ethel Rubin, Tao Zhu, Ji Shin Lee, Pedram Argani, Saraswati Sukumar
Journal: Cancer Research
Cancer Res (2006) 66 (19): 9527–9534.
https://doi.org/10.1158/0008-5472.CAN-05-4470
Published: 03 October 2006
View articletitled, HOXB7, a Homeodomain Protein, Is Overexpressed in Breast Cancer and Confers Epithelial-Mesenchymal Transition
Open the PDF for HOXB7, a Homeodomain Protein, Is Overexpressed in Breast Cancer and Confers Epithelial-Mesenchymal Transition in another window
Journal Articles

HOXA5-induced apoptosis in breast cancer cells is mediated by caspases-2 and caspase-8

Hexin Chen, Seung Chung, Saraswati Sukumar
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1113.
Published: 01 April 2004
View articletitled, HOXA5-induced apoptosis in breast cancer cells is mediated by caspases-2 and caspase-8