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Journal Articles

Abstract 4404: EZH2 modulates mRNA splicing in chronic myeloid leukemia through the repression of splicing factors and exerts part of its oncogenic function through the regulation of CELF2

Reinhard Brunmeir, Ying Li, Baohong Lin, Leong Qiao Zheng, Henry Yang, Wee Joo Chng
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4404.
https://doi.org/10.1158/1538-7445.AM2024-4404
Published: 22 March 2024
View articletitled, Abstract 4404: EZH2 modulates mRNA splicing in chronic myeloid leukemia through the repression of splicing factors and exerts part of its oncogenic function through the regulation of CELF2
Journal Articles

Targeting RNA Exonuclease XRN1 Potentiates Efficacy of Cancer Immunotherapy

Xue-Bin Ran, Ling-Wen Ding, Qiao-Yang Sun, Henry Yang, Jonathan W. Said, Lao Zhentang, Vikas Madan, Pushkar Dakle, Jin-Fen Xiao, Xinyi Loh, Ying Li, Liang Xu, Xiao-Qiang Xiang, Ling-Zhi Wang, Boon Cher Goh, De-Chen Lin, Wee Joo Chng, Soo-Yong Tan, Sudhakar Jha, H. Phillip Koeffler
Journal: Cancer Research
Cancer Res (2023) 83 (6): 922–938.
https://doi.org/10.1158/0008-5472.CAN-21-3052
Published: 15 March 2023
View articletitled, Targeting RNA Exonuclease XRN1 Potentiates Efficacy of Cancer Immunotherapy
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Includes: Supplementary data
Journal Articles

Abstract LB189: Three-dimensional genome organization maps in normal haematopoietic stem cells and acute myeloid leukemia

Benny Wang, Lingshi Kong, Deepak Babu, Ruchi Choudhary, Winnie Fam, Jia Qi Tng, Yufen Goh, Xin Liu, Fang Fang Song, Priscella Chia, Ming Chun Chan, Omer An, Cheng Yong Tham, Touati Benoukraf, Henry Yang, Wilson Wang, Wee Joo Chng, Daniel Tenen, Melissa J. Fullwood
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): LB189.
https://doi.org/10.1158/1538-7445.AM2021-LB189
Published: 01 July 2021
View articletitled, Abstract LB189: Three-dimensional genome organization maps in normal haematopoietic stem cells and acute myeloid leukemia
Journal Articles

Abstract 2443: APOBEC3G is a sex-specific determinant of post-transcriptional RNA processing and survival in diffuse large B-cell lymphoma

Joanna D. Wardyn, Michal M. Hoppe, Allison S. Chan, Jia Li, Omer An, Shruthi Venguidessane, Dominic P. Sheng, Henry Yang, Gene W. Yeo, Daniel J. Hodson, Reuben S. Harris, Anand D. Jeyasekharan
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2443.
https://doi.org/10.1158/1538-7445.AM2021-2443
Published: 01 July 2021
View articletitled, Abstract 2443: APOBEC3G is a sex-specific determinant of post-transcriptional RNA processing and survival in diffuse large B-cell lymphoma
Journal Articles

“3G” Trial: An RNA Editing Signature to Guide Gastric Cancer Chemotherapy

Omer An, Yangyang Song, Xinyu Ke, Jimmy Bok-Yan So, Raghav Sundar, Henry Yang, Sun Young Rha, Ming Hui Lee, Su Ting Tay, Xuewen Ong, Angie Lay Keng Tan, Matthew Chau Hsien Ng, Erwin Tantoso, Leilei Chen, Patrick Tan, Wei Peng Yong
Journal: Cancer Research
Series: Author Choice
Cancer Res (2021) 81 (10): 2788–2798.
https://doi.org/10.1158/0008-5472.CAN-20-2872
Published: 15 May 2021
View articletitled, “3G” Trial: An RNA Editing Signature to Guide Gastric Cancer Chemotherapy
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Includes: Supplementary data
Journal Articles

Systematic Analysis of Intronic miRNAs Reveals Cooperativity within the Multicomponent FTX Locus to Promote Colon Cancer Development

Zhi Hao Kwok, Bin Zhang, Xiao Hong Chew, Jia Jia Chan, Velda Teh, Henry Yang, Dennis Kappei, Yvonne Tay
Journal: Cancer Research
Cancer Res (2021) 81 (5): 1308–1320.
https://doi.org/10.1158/0008-5472.CAN-20-1406
Published: 01 March 2021
View articletitled, Systematic Analysis of Intronic miRNAs Reveals Cooperativity within the Multicomponent FTX Locus to Promote Colon Cancer Development
Open the PDF for Systematic Analysis of Intronic miRNAs Reveals Cooperativity within the Multicomponent FTX Locus to Promote Colon Cancer Development in another window
Includes: Supplementary data
Journal Articles

RNA-Binding Protein ZFP36L1 Suppresses Hypoxia and Cell-Cycle Signaling

Xin-Yi Loh, Qiao-Yang Sun, Ling-Wen Ding, Anand Mayakonda, Nachiyappan Venkatachalam, Mei-Shi Yeo, Tiago C. Silva, Jin-Fen Xiao, Ngan B. Doan, Jonathan W. Said, Xue-Bin Ran, Si-Qin Zhou, Pushkar Dakle, Pavithra Shyamsunder, Angele Pei-Fern Koh, Ruby Yun-Ju Huang, Benjamin P. Berman, Soo-Yong Tan, Henry Yang, De-Chen Lin, H. Phillip Koeffler
Journal: Cancer Research
Cancer Res (2020) 80 (2): 219–233.
https://doi.org/10.1158/0008-5472.CAN-18-2796
Published: 15 January 2020
View articletitled, RNA-Binding Protein ZFP36L1 Suppresses Hypoxia and Cell-Cycle Signaling
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Includes: Supplementary data
Journal Articles

Abstract 971: PRMT5 modulates splicing for genome integrity and preserves proteostasis of hematopoietic stem cells

Darren Qiancheng Tan, Ying Li, Chong Yang, Jia Li, Shi Hao Tan, Desmond W. Chin, Ayako Nakamura-Ishizu, Henry Yang, Toshio Suda
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 971.
https://doi.org/10.1158/1538-7445.AM2019-971
Published: 01 July 2019
View articletitled, Abstract 971: PRMT5 modulates splicing for genome integrity and preserves proteostasis of hematopoietic stem cells
Journal Articles

Abstract 5457: The relationship between ADAR1 and STAT3 and its relevance in multiple myeloma

Phaik Ju Teoh, Tae Hoon Chung, Henry Yang, Polly Chen, Wee Joo Chng
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5457.
https://doi.org/10.1158/1538-7445.AM2018-5457
Published: 01 July 2018
View articletitled, Abstract 5457: The relationship between ADAR1 and STAT3 and its relevance in multiple myeloma
Journal Articles

Abstract 1524: BCL6 modulates the TP53 and STAT pathways in glioma

Ye Chen, Liang Xu, Marina Dutra-Clarke, Anand Mayakonda, De-Chen Lin, Lynnette Koh, Yuk Kien Chong, Edwin Sandanaraj, Vikas Madan, Henry Yang, Ngan Doan, Jonathan W. Said, William H. Yong, Markus Müschen, Beng Ti Ang, Carol Tang, Joshua J. Breunig, Phillip Koeffler
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1524.
https://doi.org/10.1158/1538-7445.AM2017-1524
Published: 01 July 2017
View articletitled, Abstract 1524: BCL6 modulates the TP53 and STAT pathways in glioma
Journal Articles

Abstract 2569: BCL6 promotes glioma and serves as a novel therapeutic target

Liang Xu, Ye CHEN, Marina Dutra-Clarke, Anand Mayakonda, Masaharu Hazawa, Steve E. Savinoff, Ngan Doan, Jonathan W. Said, William H. Yong, Henry Yang, Ling-Wen Ding, Yan-Yi Jiang, Jeffrey W. Tyner, Jianhong Ching, Jean-Paul Kovalik, Markus Müschen, Joshua J. Breunig, De-Chen Lin, Phillip Koeffler
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2569.
https://doi.org/10.1158/1538-7445.AM2017-2569
Published: 01 July 2017
View articletitled, Abstract 2569: BCL6 promotes glioma and serves as a novel therapeutic target
Journal Articles

Abstract 2450: Mutational profiling of MLL-PTD acute myeloid leukemia

Lingwen Ding, Qiaoyang Sun, Kar-Tong Tan, Wenwen Chien, Anand Mayakonda, Dechen Lin, Xinyi Loh, Jinfen Xiao, Manja Meggendorfer, Tamara Alpermann, Manoj Garg, Su-Lin Lim, Vikas Madan, Norimichi Hattori, Yasunobu Nagata, Satoru Miyano, Allen Yeoh Eng Juh, Hsin-An Hou, Yan-Yi Jiang, Yan-Yi Jiang, Sumiko Takao, Li-Zhen Liu, Siew-Zhuan Tan, Siew-Zhuan Tan, Michael Lill, Mutsumi Hayashi, Akitoshi Kinoshita, Hagop M. Kantarjian, Steven M. Kornblau, Seishi Ogawa, Torsten Haferlach, Henry Yang, H. Phillip Koeffler
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2450.
https://doi.org/10.1158/1538-7445.AM2017-2450
Published: 01 July 2017
View articletitled, Abstract 2450: Mutational profiling of MLL-PTD acute myeloid leukemia
Journal Articles

Abstract 806: MGA is a potential tumor suppressor in acute myeloid leukemia

Qiaoyang Sun, Lingwen Ding, Kar-Tong Tan, Wenwen Chien, Xinyi Loh, Jinfen Xiao, Anand Mayakonda, Dechen Lin, Yanyi Jiang, Henry Yang, Sigal Gery, H. Phillip Koeffler
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 806.
https://doi.org/10.1158/1538-7445.AM2017-806
Published: 01 July 2017
View articletitled, Abstract 806: MGA is a potential tumor suppressor in acute myeloid leukemia
Journal Articles

Mutational Landscape of Pediatric Acute Lymphoblastic Leukemia

Ling-Wen Ding, Qiao-Yang Sun, Kar-Tong Tan, Wenwen Chien, Anand Mayakonda Thippeswamy, Allen Eng Juh Yeoh, Norihiko Kawamata, Yasunobu Nagata, Jin-Fen Xiao, Xin-Yi Loh, De-Chen Lin, Manoj Garg, Yan-Yi Jiang, Liang Xu, Su-Lin Lim, Li-Zhen Liu, Vikas Madan, Masashi Sanada, Lucia Torres Fernández, Hema Preethi, Michael Lill, Hagop M. Kantarjian, Steven M. Kornblau, Satoru Miyano, Der-Cherng Liang, Seishi Ogawa, Lee-Yung Shih, Henry Yang, H. Phillip Koeffler
Journal: Cancer Research
Cancer Res (2017) 77 (2): 390–400.
https://doi.org/10.1158/0008-5472.CAN-16-1303
Published: 16 January 2017
View articletitled, Mutational Landscape of Pediatric Acute Lymphoblastic Leukemia
Open the PDF for Mutational Landscape of Pediatric Acute Lymphoblastic Leukemia in another window
Includes: Supplementary data
Journal Articles

CRM1 Inhibition Promotes Cytotoxicity in Ewing Sarcoma Cells by Repressing EWS-FLI1–Dependent IGF-1 Signaling

Haibo Sun, De-Chen Lin, Qi Cao, Xiao Guo, Helene Marijon, Zhiqiang Zhao, Sigal Gery, Liang Xu, Henry Yang, Brendan Pang, Victor Kwan Min Lee, Huey Jin Lim, Ngan Doan, Jonathan W. Said, Peiguo Chu, Anand Mayakonda, Tom Thomas, Charles Forscher, Erkan Baloglu, Sharon Shacham, Raja Rajalingam, H. Phillip Koeffler
Journal: Cancer Research
Cancer Res (2016) 76 (9): 2687–2697.
https://doi.org/10.1158/0008-5472.CAN-15-1572
Published: 01 May 2016
View articletitled, CRM1 Inhibition Promotes Cytotoxicity in Ewing Sarcoma Cells by Repressing EWS-FLI1–Dependent IGF-1 Signaling
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Includes: Supplementary data
Journal Articles

Abstract A2-20: Integrative study of genomic alterations in liposarcoma

Deepika Kanojia, Manoj Garg, Yasunobu Nagata, Dhong Hyun Lee, Hans-Ulrich Klein, Christoph Bartenhagen, Anand M T, Ngan B Doan, Jonathan W Said, Henry Yang, Charles Forscher, Martin Dugas, Seishi Ogawa, H Phillip Koeffler
Journal: Cancer Research
Cancer Res (2015) 75 (22_Supplement_1): A2-20.
https://doi.org/10.1158/1538-7445.TRANSCAGEN-A2-20
Published: 15 November 2015
View articletitled, Abstract A2-20: Integrative study of genomic alterations in liposarcoma
Journal Articles

Abstract 3939: The genomic landscape of nasopharyngeal carcinoma

DECHEN LIN, Xuan Meng, Masaharu Hazawa, Yasunobu Nagata, Ana Maria Varela, Liang Xu, Yusuke Sato, Li-Zhen Liu, Ling-Wen Ding, Arjun Sharma, Boon Cher Goh, Soo Chin Lee, Bengt Fredrik Petersson, Feng Gang Yu, Paul Macary, Min Zin Oo, Soh Ha Chan, Henry Yang, Seishi Ogawa, H. Phillip Koeffler
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3939.
https://doi.org/10.1158/1538-7445.AM2015-3939
Published: 01 August 2015
View articletitled, Abstract 3939: The genomic landscape of nasopharyngeal carcinoma
Journal Articles

Abstract 2868: SETDB1 accelerates non-small cell lung cancer (NSCLC) tumorigenesis through WNT signalling pathway

Qiaoyang Sun, Lingwen Ding, Jinfen Xiao, Lee Goodglick, David Chia, Vei Mah, Mohammad Alavi, Ngan Doan, Jonathan W. Said, Henry Yang, H.Phillip Koeffler
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2868.
https://doi.org/10.1158/1538-7445.AM2015-2868
Published: 01 August 2015
View articletitled, Abstract 2868: SETDB1 accelerates non-small cell lung cancer (NSCLC) tumorigenesis through WNT signalling pathway
Journal Articles

Abstract 4944: Identification of B-cell lymphoma 6 as a novel therapeutic target in glioblastoma

Ye Chen, Liang Xu, Masaharu Hazawa, Anand M. Thippeswamy, Henry Yang, Markus Müschen, De-Chen Lin, Phillip Koeffler
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4944.
https://doi.org/10.1158/1538-7445.AM2015-4944
Published: 01 August 2015
View articletitled, Abstract 4944: Identification of B-cell lymphoma 6 as a novel therapeutic target in glioblastoma
Journal Articles

Abstract 542: CEACAM6 is upregulated by the H Pylori CAG-A oncoprotein, and is a candidate biomarker for the diagnosis of early gastric cancer

Anand D. Jeyasekharan, Rony K. Roy, Michal M. Hoppe, Kar Tong Tan, Henry Yang, Patrick Tan, Phillip H. Koeffler, Khay Guan Yeoh, Singapore Gastric Cancer Consortium
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 542.
https://doi.org/10.1158/1538-7445.AM2015-542
Published: 01 August 2015
View articletitled, Abstract 542: CEACAM6 is upregulated by the H Pylori CAG-A oncoprotein, and is a candidate biomarker for the diagnosis of early gastric cancer