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Henning Walczak
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Journal Articles

Abstract #2039: Targeting XIAP overcomes Bcl-2-imposed resistance of pancreatic carcinoma towards TRAIL in vitro and in vivo

Free
Dominic Stadel, Meike Vogler, Tobias Haas, Henning Walczak, Klaus-Michael Debatin, Simone Fulda
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2039.
Published: 01 May 2009
View articletitled, Abstract #2039: Targeting XIAP overcomes Bcl-2-imposed resistance of pancreatic carcinoma towards TRAIL in vitro and in vivo
Journal Articles

Small Molecule XIAP Inhibitors Enhance TRAIL-Induced Apoptosis and Antitumor Activity in Preclinical Models of Pancreatic Carcinoma

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Meike Vogler, Henning Walczak, Dominic Stadel, Tobias L. Haas, Felicitas Genze, Marjana Jovanovic, Umesh Bhanot, Cornelia Hasel, Peter Möller, Jürgen E. Gschwend, Thomas Simmet, Klaus-Michael Debatin, Simone Fulda
Journal: Cancer Research
Cancer Res (2009) 69 (6): 2425–2434.
https://doi.org/10.1158/0008-5472.CAN-08-2436
Published: 17 March 2009
View articletitled, Small Molecule XIAP Inhibitors Enhance TRAIL-Induced Apoptosis and Antitumor Activity in Preclinical Models of Pancreatic Carcinoma
Open the PDF for Small Molecule XIAP Inhibitors Enhance TRAIL-Induced Apoptosis and Antitumor Activity in Preclinical Models of Pancreatic Carcinoma in another window
Includes: Supplementary data
Journal Articles

Targeting XIAP Bypasses Bcl-2–Mediated Resistance to TRAIL and Cooperates with TRAIL to Suppress Pancreatic Cancer Growth In vitro and In vivo

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Meike Vogler, Henning Walczak, Dominic Stadel, Tobias L. Haas, Felicitas Genze, Marjana Jovanovic, Jürgen E. Gschwend, Thomas Simmet, Klaus-Michael Debatin, Simone Fulda
Journal: Cancer Research
Cancer Res (2008) 68 (19): 7956–7965.
https://doi.org/10.1158/0008-5472.CAN-08-1296
Published: 30 September 2008
View articletitled, Targeting XIAP Bypasses Bcl-2–Mediated Resistance to TRAIL and Cooperates with TRAIL to Suppress Pancreatic Cancer Growth In vitro and In vivo
Open the PDF for Targeting XIAP Bypasses Bcl-2–Mediated Resistance to TRAIL and Cooperates with TRAIL to Suppress Pancreatic Cancer Growth In vitro and In vivo in another window
Includes: Supplementary data
Journal Articles

Sensitizer/inducer strategy of XIAP inhibitors combined with TRAIL: A new paradigm for apoptosis-based therapy of pancreatic cancer

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Meike Vogler, Henning Walczak, Dominic Stadel, Tobias Haas, Felicitas Genze, Marjana Jovanovic, Umesh Bhanot, Cornelia Hasel, Peter Moeller, Juergen Gschwend, Thomas Simmet, Klaus-Michael Debatin, Simone Fulda
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2550.
Published: 01 May 2008
View articletitled, Sensitizer/inducer strategy of XIAP inhibitors combined with TRAIL: A new paradigm for apoptosis-based therapy of pancreatic cancer
Journal Articles

Detachment sensitizes skin carcinoma cells to TRAIL and CD95L-induced apoptosis and explains how death ligands can facilitate metastasis suppression

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Anne Grosse-Wilde, Oksana Voloshanenko, Christopher Kemp, Henning Walczak
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1183.
Published: 01 May 2008
View articletitled, Detachment sensitizes skin carcinoma cells to TRAIL and CD95L-induced apoptosis and explains how death ligands can facilitate metastasis suppression
Journal Articles

Impaired survival of irradiated mice deficient for the apoptosis-inducing TRAIL-R

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Anne Grosse-Wilde, Kay Gurley, Henning Walczak, Christopher Kemp
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 5181.
Published: 01 May 2007
View articletitled, Impaired survival of irradiated mice deficient for the apoptosis-inducing TRAIL-R
Journal Articles

Cyclooxygenase-2 Inhibition Induces Apoptosis Signaling via Death Receptors and Mitochondria in Hepatocellular Carcinoma

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Michael A. Kern, Anke M. Haugg, Andreas F. Koch, Tobias Schilling, Kai Breuhahn, Henning Walczak, Binje Fleischer, Christian Trautwein, Christoph Michalski, Henning Schulze-Bergkamen, Helmut Friess, Wolfgang Stremmel, Peter H. Krammer, Peter Schirmacher, Martina Müller
Journal: Cancer Research
Cancer Res (2006) 66 (14): 7059–7066.
https://doi.org/10.1158/0008-5472.CAN-06-0325
Published: 18 July 2006
View articletitled, Cyclooxygenase-2 Inhibition Induces Apoptosis Signaling via Death Receptors and Mitochondria in Hepatocellular Carcinoma
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Journal Articles

Analysis of TRAIL-receptor-deficient mice in a two-stage skin tumorigenesis model reveals a role for TRAIL-receptor in suppression of metastasis formation

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Anne Grosse-Wilde, Shawn L. Bailey, Erich F. Greiner, Kay E. Gurley, Claudia Rappl, Johannes F. Coy, Peter H. Krammer, Gunther Schutz, Christopher J. Kemp, Henning Walczak
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 562.
Published: 15 April 2006
View articletitled, Analysis of TRAIL-receptor-deficient mice in a two-stage skin tumorigenesis model reveals a role for TRAIL-receptor in suppression of metastasis formation
Journal Articles

PEA-15/PED is phosphorylated in response to glucose withdrawal and protects glioblastoma cells from glucose deprivation-induced cell death

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Anika Eckert, Barbara Bock, Jaromir Sykora, Tobias Haas, Kerstin Schultze, Christel Herold-Mende, Otmar Wiestler, Henning Walczak, Wilfried Roth
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 579.
Published: 15 April 2006
View articletitled, PEA-15/PED is phosphorylated in response to glucose withdrawal and protects glioblastoma cells from glucose deprivation-induced cell death
Journal Articles

Tumor Necrosis Factor-related Apoptosis-inducing Ligand Retains Its Apoptosis-inducing Capacity on Bcl-2- or Bcl-xL-overexpressing Chemotherapy-resistant Tumor Cells

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Henning Walczak, Axel Bouchon, Heiko Stahl, Peter H. Krammer
Journal: Cancer Research
Cancer Res (2000) 60 (11): 3051–3057.
Published: 01 June 2000
View articletitled, Tumor Necrosis Factor-related Apoptosis-inducing Ligand Retains Its Apoptosis-inducing Capacity on Bcl-2- or Bcl-xL-overexpressing Chemotherapy-resistant Tumor Cells
Open the PDF for Tumor Necrosis Factor-related Apoptosis-inducing Ligand Retains Its Apoptosis-inducing Capacity on Bcl-2- or Bcl-xL-overexpressing Chemotherapy-resistant Tumor Cells in another window
Journal Articles

Regulation of Tumor Necrosis Factor-related Apoptosis-inducing Ligand Sensitivity in Primary and Transformed Human Keratinocytes

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Martin Leverkus, Manfred Neumann, Thilo Mengling, Charles T. Rauch, Eva-Bettina Bröcker, Peter H. Krammer, Henning Walczak
Journal: Cancer Research
Cancer Res (2000) 60 (3): 553–559.
Published: 01 February 2000
View articletitled, Regulation of Tumor Necrosis Factor-related Apoptosis-inducing Ligand Sensitivity in Primary and Transformed Human Keratinocytes
Open the PDF for Regulation of Tumor Necrosis Factor-related Apoptosis-inducing Ligand Sensitivity in Primary and Transformed Human Keratinocytes in another window