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Abstract 908: Development of a cell proliferation assay to be used as a read-out system for determining the in vivo potency of bevacizumab in neutralizing the biological activity of VEGF in cancer patients

Madelon Q. Wentink, Henk J. Broxterman, Tanja D. de Gruijl, Roberto Pili, Hans J. van der Vliet, Arjan W. Griffioen, Henk M.W. Verheul

Cancer Res (2014) 74 (19_Supplement): 908.

https://doi.org/10.1158/1538-7445.AM2014-908

Published: 01 October 2014

View articletitled, Abstract 908: Development of a cell proliferation assay to be used as a read-out system for determining the in vivo potency of bevacizumab in neutralizing the biological activity of VEGF in cancer patients

Journal Articles

Abstract 2989: High-dose, intermittent sunitinib as an alternative treatment strategy

Maria Rovithi, Richard R. de Haas, Richard J. Honeywell, Johannes Voortman, Arjan W. Griffioen, Mariette Labots, Anne Marije Luik, Godefridus J. Peters, Henk J. Broxterman, Henk M.w. Verheul

Cancer Res (2014) 74 (19_Supplement): 2989.

https://doi.org/10.1158/1538-7445.AM2014-2989

Published: 01 October 2014

View articletitled, Abstract 2989: High-dose, intermittent sunitinib as an alternative treatment strategy

Journal Articles

Abstract 1621: Short-time exposure to high concentrations of sunitinib causes tumor cell death.

Maria Rovithi, Dennis Poel, Jens Voortman, Mariette Labots, Henk Dekker, Kristy J. Gotink, Henk J. Broxterman, Henk M.W. Verheul

Cancer Res (2013) 73 (8_Supplement): 1621.

https://doi.org/10.1158/1538-7445.AM2013-1621

Published: 15 April 2013

View articletitled, Abstract 1621: Short-time exposure to high concentrations of sunitinib causes tumor cell death.

Journal Articles

Abstract 5641: Sunitinib inhibits AXL phosphorylation in tumor cells.

Johannes C. Van der Mijn, Kristy J. Gotink, Richard R. de Haas, Henk Dekker, Connie R. Jimenez, Henk J. Broxterman, Henk M.w. Verheul

Cancer Res (2013) 73 (8_Supplement): 5641.

https://doi.org/10.1158/1538-7445.AM2013-5641

Published: 15 April 2013

View articletitled, Abstract 5641: Sunitinib inhibits AXL phosphorylation in tumor cells.

Journal Articles

Abstract 1613: In vitro acquired tumor cell resistance to sunitinib contributes to an in vivo resistant phenotype.

Kristy J. Gotink, Roberto Pili, Richard J. Honeywell, Arjan W. Griffioen, Godefridus J. Peters, Henk J. Broxterman, Henk MW Verheul

Cancer Res (2013) 73 (8_Supplement): 1613.

https://doi.org/10.1158/1538-7445.AM2013-1613

Published: 15 April 2013

View articletitled, Abstract 1613: In vitro acquired tumor cell resistance to sunitinib contributes to an in vivo resistant phenotype.

Journal Articles

Abstract 176: Kinase activity of tumor-derived exosomes as a potential biomarker for response to treatment

Johannes C. van der Mijn, Connie R. Jimenez, Sander R. Piersma, Henk Dekker, Mariette Labots, Lisette M. Schutte, Egbert F. Smit, Henk J. Broxterman, Bakhous Tannous, Tom Wurdinger, Henk M.W. Verheul

Cancer Res (2012) 72 (8_Supplement): 176.

https://doi.org/10.1158/1538-7445.AM2012-176

Published: 15 April 2012

View articletitled, Abstract 176: Kinase activity of tumor-derived exosomes as a potential biomarker for response to treatment

Journal Articles

Abstract 1374: Cross-resistance and sensitivity of sunitinib resistant tumor cells

Kristy J. Gotink, Henk J. Broxterman, Richard R. de Haas, Maria N. Rovithi, Roberto Pili, Henk MW Verheul

Cancer Res (2012) 72 (8_Supplement): 1374.

https://doi.org/10.1158/1538-7445.AM2012-1374

Published: 15 April 2012

View articletitled, Abstract 1374: Cross-resistance and sensitivity of sunitinib resistant tumor cells

Journal Articles

Abstract 3608: Measurement of kinase activity in cancer cell lines and tumor tissue using a tyrosine kinase peptide substrate array

Mariette Labots, Kristy J. Gotink, Henk Dekker, Johannes C. van der Mijn, Henk J. Broxterman, Maria N. Rovithi, Connie R. Jiménez, Henk M.W. Verheul

Cancer Res (2012) 72 (8_Supplement): 3608.

https://doi.org/10.1158/1538-7445.AM2012-3608

Published: 15 April 2012

View articletitled, Abstract 3608: Measurement of kinase activity in cancer cell lines and tumor tissue using a tyrosine kinase peptide substrate array

Journal Articles

Abstract 2852: Lysosomal sequestration of sunitinib may play a role in its resistance

Kristy J. Gotink, Henk J. Broxterman, Mariette Labots, Richard R. de Haas, Henk Dekker, Richard J. Honeywell, Yehuda G. Assaraf, Roberto Pili, Godefridus J. Peters, Henk M.W. Verheul

Cancer Res (2011) 71 (8_Supplement): 2852.

https://doi.org/10.1158/1538-7445.AM2011-2852

Published: 15 April 2011

View articletitled, Abstract 2852: Lysosomal sequestration of sunitinib may play a role in its resistance

Journal Articles

Abstract 4956: CD34^bright/CD133^neg candidate circulating endothelial progenitor cells (ccEPCs) are a potential biomarker during treatment with sunitinib or bevacizumab

Laura Vroling, Astrid A.M. van der Veldt, Richard R de Haas, Gerrit Jan Schuurhuis, Hester van Cruijsen, Alfons J.M. van den Eertwegh, Klaas Hoekman, Victor W.M. van Hinsbergh, Epie Boven, Egbert F. Smit, Henk J. Broxterman

Cancer Res (2008) 68 (9_Supplement): 4956.

https://doi.org/10.1158/1538-7445.AM2008-4956

Published: 15 May 2008

View articletitled, Abstract 4956: CD34bright/CD133neg candidate circulating endothelial progenitor cells (ccEPCs) are a potential biomarker during treatment with sunitinib or bevacizumab

Journal Articles

Analysis of circulating endothelial (progenitor) cells by flow cytometry and a short-term colony assay (CFU-EC)

Laura Vroling, Yuana Yuana, Klaas Hoekman, Hester Van Cruijsen, Epie Boven, Chad Gundy, Gerrit Jan Schuurhuis, Henk J. Broxterman

Cancer Res (2006) 66 (8_Supplement): 71–72.

Published: 15 April 2006

View articletitled, Analysis of circulating endothelial (progenitor) cells by flow cytometry and a short-term colony assay (CFU-EC)

Journal Articles

Peptide Transport by the Multidrug Resistance Protein MRP1

Mariska C. de Jong, Jerry W. Slootstra, George L. Scheffer, Anouk B. Schroeijers, Wouter C. Puijk, Remco Dinkelberg, Marcel Kool, Henk J. Broxterman, Rob H. Meloen, Rik J. Scheper

Cancer Res (2001) 61 (6): 2552–2557.

Published: 03 March 2001

View articletitled, Peptide Transport by the Multidrug Resistance Protein MRP1

Journal Articles

Antifolate Resistance Mediated by the Multidrug Resistance Proteins MRP1 and MRP2

Jan Hendrik Hooijberg, Henk J. Broxterman, Marcel Kool, Yehuda G. Assaraf, Godefridus J. Peters, Paul Noordhuis, Rik J. Scheper, Piet Borst, Herbert M. Pinedo, Gerrit Jansen

Cancer Res (1999) 59 (11): 2532–2535.

Published: 01 June 1999

View articletitled, Antifolate Resistance Mediated by the Multidrug Resistance Proteins MRP1 and MRP2

Journal Articles

Methods to Detect P-Glycoprotein-associated Multidrug Resistance in Patients' Tumors: Consensus Recommendations

Cancer Res (1996) 56 (13): 3010–3020.

Published: 01 July 1996

View articletitled, Methods to Detect P-Glycoprotein-associated Multidrug Resistance in Patients' Tumors: Consensus Recommendations

Journal Articles

Correlation of Multidrug Resistance with Decreased Drug Accumulation, Altered Subcellular Drug Distribution, and Increased P-Glycoprotein Expression in Cultured SW-1573 Human Lung Tumor Cells

Hiskias G. Keizer, Gerrit J. Schuurhuis, Henk J. Broxterman, Jan Lankelma, Willem G. E. J. Schoonen, Johan van Rijn, Herbert M. Pinedo, Hans Joenje

Cancer Res (1989) 49 (11): 2988–2993.

Published: 01 June 1989

View articletitled, Correlation of Multidrug Resistance with Decreased Drug Accumulation, Altered Subcellular Drug Distribution, and Increased P-Glycoprotein Expression in Cultured SW-1573 Human Lung Tumor Cells

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Abstract 908: Development of a cell proliferation assay to be used as a read-out system for determining the in vivo potency of bevacizumab in neutralizing the biological activity of VEGF in cancer patients

Abstract 2989: High-dose, intermittent sunitinib as an alternative treatment strategy

Abstract 1621: Short-time exposure to high concentrations of sunitinib causes tumor cell death.

Abstract 5641: Sunitinib inhibits AXL phosphorylation in tumor cells.

Abstract 1613: In vitro acquired tumor cell resistance to sunitinib contributes to an in vivo resistant phenotype.

Abstract 176: Kinase activity of tumor-derived exosomes as a potential biomarker for response to treatment

Abstract 1374: Cross-resistance and sensitivity of sunitinib resistant tumor cells

Abstract 3608: Measurement of kinase activity in cancer cell lines and tumor tissue using a tyrosine kinase peptide substrate array

Abstract 2852: Lysosomal sequestration of sunitinib may play a role in its resistance

Abstract 4956: CD34^bright/CD133^neg candidate circulating endothelial progenitor cells (ccEPCs) are a potential biomarker during treatment with sunitinib or bevacizumab

Analysis of circulating endothelial (progenitor) cells by flow cytometry and a short-term colony assay (CFU-EC)

Peptide Transport by the Multidrug Resistance Protein MRP1

Antifolate Resistance Mediated by the Multidrug Resistance Proteins MRP1 and MRP2

Methods to Detect P-Glycoprotein-associated Multidrug Resistance in Patients' Tumors: Consensus Recommendations

Correlation of Multidrug Resistance with Decreased Drug Accumulation, Altered Subcellular Drug Distribution, and Increased P-Glycoprotein Expression in Cultured SW-1573 Human Lung Tumor Cells

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