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Helga Raab
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Journal Articles

Abstract 650: A high-throughput conjugation strategy for the selection of THIOMAB™ antibodies with desired properties for antibody-drug conjugation

Free
Rachana V. Ohri, Sunil Bhakta, Helga Raab, Richard Vandlen, Jagath Junutula, Hans Erickson
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 650.
https://doi.org/10.1158/1538-7445.AM2015-650
Published: 01 August 2015
View articletitled, Abstract 650: A high-throughput conjugation strategy for the selection of THIOMAB™ antibodies with desired properties for antibody-drug conjugation
Journal Articles

Abstract 4396: Conjugation site modulates the stability and biological activity of antibody drug conjugates

Free
Ben-Quan Shen, Keyang Xu, Luna Liu, Kathryn Parsons, Sunil Bhakta, Helga Raab, 20 more Genentech Authors, Kelly Flagella, Susan D. Spencer, Surinder Kaur, Richard H. Scheller, Mark X. Sliwkowski, Paul Polakis, Jagath Reddy Junutula
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4396.
https://doi.org/10.1158/1538-7445.AM10-4396
Published: 15 April 2010
View articletitled, Abstract 4396: Conjugation site modulates the stability and biological activity of antibody drug conjugates
Journal Articles

Antibody-Drug Conjugates for the Treatment of Non–Hodgkin's Lymphoma: Target and Linker-Drug Selection

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Andrew G. Polson, Jill Calemine-Fenaux, Pamela Chan, Wesley Chang, Erin Christensen, Suzanna Clark, Frederic J. de Sauvage, Dan Eaton, Kristi Elkins, J. Michael Elliott, Gretchen Frantz, Reina N. Fuji, Alane Gray, Kristin Harden, Gladys S. Ingle, Noelyn M. Kljavin, Hartmut Koeppen, Christopher Nelson, Saileta Prabhu, Helga Raab, Sarajane Ross, Jean-Philippe Stephan, Suzie J. Scales, Susan D. Spencer, Richard Vandlen, Bernd Wranik, Shang-Fan Yu, Bing Zheng, Allen Ebens
Journal: Cancer Research
Cancer Res (2009) 69 (6): 2358–2364.
https://doi.org/10.1158/0008-5472.CAN-08-2250
Published: 17 March 2009
View articletitled, Antibody-Drug Conjugates for the Treatment of Non–Hodgkin's Lymphoma: Target and Linker-Drug Selection
Open the PDF for Antibody-Drug Conjugates for the Treatment of Non–Hodgkin's Lymphoma: Target and Linker-Drug Selection in another window
Includes: Supplementary data
Journal Articles

Site-specific conjugation of cytotoxic drugs to antibodies substantially improves the therapeutic window

Free
Jagath Reddy Junutula, Helga Raab, Sunil Bhakta, Kathryn Parsons, Suzanna Clark, Shang-Fan Yu, Sarajane Ross, Amy Kim, Kevin McDorman, Kelly Flagella, Susan Spencer, Richard Vandlen, Henry Lowman, William Mallet, Paul Polakis, Mark Sliwkowski, Richard Scheller
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2132.
Published: 01 May 2008
View articletitled, Site-specific conjugation of cytotoxic drugs to antibodies substantially improves the therapeutic window
Journal Articles

ThioMabs: improving safety abd retaining efficacy of antibody drug conjugates

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Jagath Reddy Junutula, Helga Raab, Sunil Bhakta, Karen Ervin, Kathryn Parsons, Suzanna Clark, Debra Dugger, Edward Ha, Sarajane Ross, Charles Eigenbrot, William Leach, William Mallet, Richard Vandlen, Paul Polakis, Mark Sliwkowski, Henry Lowman, Richard Scheller
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 918.
Published: 01 May 2007
View articletitled, ThioMabs: improving safety abd retaining efficacy of antibody drug conjugates
Journal Articles

Selective inhibition of fibroblast activation protein protease based on dipeptide substrate specificity

Free
Conrad Y. Edosada, Clifford Quan, Christian Wiesmann, Thuy Tran, Dan Sutherlin, Mark Reynolds, J. Michael Elliott, Helga Raab, Wayne Fairbrother, Beni Wolf
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1027.
Published: 15 April 2006
View articletitled, Selective inhibition of fibroblast activation protein protease based on dipeptide substrate specificity
Journal Articles

Engineering novel ThioFab/Mabs for site specific conjugation of cytotoxic drugs

Free
Jagath Reddy Junutula, Helga Raab, Karen E. Ervin, Jennifer L. Speer, Debra Dugger, Charles Eigenbrot, Richard Vandlen, Mark X. Sliwkowski, Henry B. Lowman, Richard H. Scheller
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 469.
Published: 15 April 2006
View articletitled, Engineering novel ThioFab/Mabs for site specific conjugation of cytotoxic drugs