1-20 of 34
Heikki Joensuu
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Abstract 1704: Overcoming resistance in HER2-positive gastric and breast cancers: Efficacy of disitamab vedotin in preclinical models resistant to trastuzumab emtansine and trastuzumab deruxtecan

Negar Pourjamal, Vadim Le Joncour, György Vereb, Cilla Honkamaki, Jorma Isola, Jeffrey V Leyton, Pirjo Laakkonen, Heikki Joensuu, Mark Barok
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 1704.
https://doi.org/10.1158/1538-7445.AM2025-1704
Published: 21 April 2025
View articletitled, Abstract 1704: Overcoming resistance in HER2-positive gastric and breast cancers: Efficacy of disitamab vedotin in preclinical models resistant to trastuzumab emtansine and trastuzumab deruxtecan
Journal Articles

Abstract PS03-03: The spatially resolved single-cell atlas of the tumor immune architecture revealed the central role of IFN-alpha and plasmacytoid dendritic cells in triple-negative breast cancer in the Mayo Clinic cohort and FinXX trial

Saranya Chumsri, Yi Liu, Yaohua Ma, Jodi Carter, Mark Gregory, Sarah Church, Jason Reeves, Heather Ann Brauer, Sarah Warren, Heikki Joensuu, Edith Perez, Roberto Leon-Ferre, David Hillman, Judy Boughey, James Ingle, Krishna Kalari, Fergus Couch, Matthew Goetz, Keith Knutson, E. Thompson
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PS03-03.
https://doi.org/10.1158/1538-7445.SABCS23-PS03-03
Published: 02 May 2024
View articletitled, Abstract PS03-03: The spatially resolved single-cell atlas of the tumor immune architecture revealed the central role of IFN-alpha and plasmacytoid dendritic cells in triple-negative breast cancer in the Mayo Clinic cohort and FinXX trial
Journal Articles

CIP2A Interacts with TopBP1 and Drives Basal-Like Breast Cancer Tumorigenesis

Anni Laine, Srikar G. Nagelli, Caroline Farrington, Umar Butt, Anna N. Cvrljevic, Julia P. Vainonen, Femke M. Feringa, Tove J. Grönroos, Prson Gautam, Sofia Khan, Harri Sihto, Xi Qiao, Karolina Pavic, Denise C. Connolly, Pauliina Kronqvist, Laura L. Elo, Jochen Maurer, Krister Wennerberg, Rene H. Medema, Heikki Joensuu, Emilia Peuhu, Karin de Visser, Goutham Narla, Jukka Westermarck
Journal: Cancer Research
Cancer Res (2021) 81 (16): 4319–4331.
https://doi.org/10.1158/0008-5472.CAN-20-3651
Published: 15 August 2021
View articletitled, CIP2A Interacts with TopBP1 and Drives Basal-Like Breast Cancer Tumorigenesis
Open the PDF for CIP2A Interacts with TopBP1 and Drives Basal-Like Breast Cancer Tumorigenesis in another window
Includes: Supplementary data
Journal Articles

Abstract 2966: Novel ex vivo model for ERα positive breast cancer

Pauliina M. Munne, Lahja Martikainen, Iiris Räty, Kia Bertula, Nonappa Nonappa, Aino Peura, Minna Mutka, Marjut Leidenius, Tuomo Meretoja, Panu Kovanen, Johanna Mattson, Paivi Heikkila, Heikki Joensuu, Olli Ikkala, Juha T. Klefstrom
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2966.
https://doi.org/10.1158/1538-7445.AM2021-2966
Published: 01 July 2021
View articletitled, Abstract 2966: Novel ex vivo model for ERα positive breast cancer
Journal Articles

Abstract PS6-02: Spatially defined immune-related proteins and outcome in triple negative breast cancer in the FinXX trial and Mayo Clinic cohort

Saranya Chumsri, Jodi M. Carter, Yaohua Ma, Douglas Hinerfeld, Heather Ann Brauer, Sarah Warren, Torsten O. Nielsen, Karama Asleh, Heikki Joensuu, Edith A. Perez, Roberto A. Leon-Ferre, David W. Hillman, Judy C. Boughey, Minetta C. Liu, James N. Ingle, Krishna R. Kalari, Fergus J. Couch, Keith L. Knutson, Matthew P. Goetz, E. A. Thompson
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS6-02.
https://doi.org/10.1158/1538-7445.SABCS20-PS6-02
Published: 15 February 2021
View articletitled, Abstract PS6-02: Spatially defined immune-related proteins and outcome in triple negative breast cancer in the FinXX trial and Mayo Clinic cohort
Journal Articles

Abstract 1004: Quantitative digital spatial profiling reveals novel prognostic intratumoral immune signatures in triple-negative breast cancer

Jodi M. Carter, Saranya Chumsri, Yaohua Ma, Xue Wang, Jennifer M. Kachergus, Douglas Hinerfeld, Heather Ann Brauer, Sarah Warren, Heikki Joensuu, Edith A. Perez, Aubrey Thompson
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1004.
https://doi.org/10.1158/1538-7445.AM2020-1004
Published: 15 August 2020
View articletitled, Abstract 1004: Quantitative digital spatial profiling reveals novel prognostic intratumoral immune signatures in triple-negative breast cancer
Journal Articles

Abstract PD5-06: Digital spatial mapping of the immune landscape of triple negative breast cancer reveals novel features of immune-tumor cell interaction

Saranya Chumsri, Douglas Hinerfeld, Jennifer M. Kachergus, Yaohua Ma, Heather A Brauer, Sarah Warren, Xue Wang, Torsten O. Nielsen, Karama Asleh, Heikki Joensuu, Edith A. Perez, E. A. Thompson
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): PD5-06.
https://doi.org/10.1158/1538-7445.SABCS19-PD5-06
Published: 15 February 2020
View articletitled, Abstract PD5-06: Digital spatial mapping of the immune landscape of triple negative breast cancer reveals novel features of immune-tumor cell interaction
Journal Articles

Abstract P4-10-16: Reactive stroma and trastuzumab resistance in HER2-positive early breast cancer

Amir Sonnenblick, Mali Salmon-Divon, Roberto Salgado, Noam Pondé, Sibylle Loibl, Carsten Denkert, Heikki Joensuu, Pirkko-Liisa Kellokumpu-Lehtinen, Amos Azaria, Sherene Loi, Stefan Michiels, Christos Sotiriou
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P4-10-16.
https://doi.org/10.1158/1538-7445.SABCS19-P4-10-16
Published: 15 February 2020
View articletitled, Abstract P4-10-16: Reactive stroma and trastuzumab resistance in HER2-positive early breast cancer
Journal Articles

Abstract LB-251: The cancer clinical trial landscape in the EU and the Nordic countries

Jeroen Pouwels, Sebastian Soidinsalo, Heidi Haikala, Panu Jaakola, Tarja Jalava, Heikki Joensuu, Mika Mustonen, Pasi Korhonen, Panu Kovanen, Anne Lehtonen, Johanna Mattson, Outi Monni, Jukka Westermarck, Juha Klefström
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-251.
https://doi.org/10.1158/1538-7445.AM2019-LB-251
Published: 01 July 2019
View articletitled, Abstract LB-251: The cancer clinical trial landscape in the EU and the Nordic countries
Journal Articles

Abstract LB-189: Pharmacological reactivation of MYC-dependent apoptosis cooperates with anti-PD1 immunotherapy

Heidi M. Haikala, Johanna M. Anttila, Mariel Savelius, Elsa Marques, Tiina Raatikainen, Mette Ilander, Henna Hakanen, Johanna Mattson, Paivi Heikkila, Marjut Leidenius, Heikki Joensuu, Satu Mustjoki, Panu Kovanen, Martin Eilers, Joel D. Leverson, Juha T. Klefström
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-189.
https://doi.org/10.1158/1538-7445.AM2019-LB-189
Published: 01 July 2019
View articletitled, Abstract LB-189: Pharmacological reactivation of MYC-dependent apoptosis cooperates with anti-PD1 immunotherapy
Journal Articles

Abstract 756: Development of next-generation antibody-drug conjugates for resistant HER2-positive tumors

Vincent Lacasse, Jeffrey V. Leyton, Simon Beaudoin, Mark Barok, Heikki Joensuu
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 756.
https://doi.org/10.1158/1538-7445.AM2018-756
Published: 01 July 2018
View articletitled, Abstract 756: Development of next-generation antibody-drug conjugates for resistant HER2-positive tumors
Journal Articles

CD73 Promotes Resistance to HER2/ErbB2 Antibody Therapy

Martin Turcotte, David Allard, Deepak Mittal, Yacine Bareche, Laurence Buisseret, Vinu José, Sandra Pommey, Vincent Delisle, Sherene Loi, Heikki Joensuu, Pirkko-Liisa Kellokumpu-Lehtinen, Christos Sotiriou, Mark J. Smyth, John Stagg
Journal: Cancer Research
Cancer Res (2017) 77 (20): 5652–5663.
https://doi.org/10.1158/0008-5472.CAN-17-0707
Published: 15 October 2017
View articletitled, CD73 Promotes Resistance to HER2/ErbB2 Antibody Therapy
Open the PDF for CD73 Promotes Resistance to HER2/ErbB2 Antibody Therapy in another window
Includes: Supplementary data
Journal Articles

Abstract 673: Exploration of tissue morphologies in breast cancer samples using unsupervised machine learning

Riku Turkki, Dmitrii Bychkov, Nina Linder, Jorma Isola, Heikki Joensuu, Johan Lundin
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 673.
https://doi.org/10.1158/1538-7445.AM2017-673
Published: 01 July 2017
View articletitled, Abstract 673: Exploration of tissue morphologies in breast cancer samples using unsupervised machine learning
Journal Articles

Human Chorionic Gonadotropin Does Not Correlate with Risk for Maternal Breast Cancer: Results from the Finnish Maternity Cohort

Renée T. Fortner, Helena Schock, Rudolf Kaaks, Matti Lehtinen, Eero Pukkala, Hans-Åke Lakso, Minna Tanner, Raija Kallio, Heikki Joensuu, Jaana Korpela, Adetunji T. Toriola, Göran Hallmans, Kjell Grankvist, Anne Zeleniuch-Jacquotte, Paolo Toniolo, Eva Lundin, Heljä-Marja Surcel
Journal: Cancer Research
Cancer Res (2017) 77 (1): 134–141.
https://doi.org/10.1158/0008-5472.CAN-16-1524
Published: 02 January 2017
View articletitled, Human Chorionic Gonadotropin Does Not Correlate with Risk for Maternal Breast Cancer: Results from the Finnish Maternity Cohort
Open the PDF for Human Chorionic Gonadotropin Does Not Correlate with Risk for Maternal Breast Cancer: Results from the Finnish Maternity Cohort in another window
Includes: Supplementary data
Journal Articles

Improved Treatment of Breast Cancer with Anti-HER2 Therapy Requires Interleukin-21 Signaling in CD8+ T Cells

Deepak Mittal, Franco Caramia, Stefan Michiels, Heikki Joensuu, Pirkko-Liisa Kellokumpu-Lehtinen, Christos Sotiriou, Sherene Loi, Mark J. Smyth
Journal: Cancer Research
Cancer Res (2016) 76 (2): 264–274.
https://doi.org/10.1158/0008-5472.CAN-15-1567
Published: 14 January 2016
View articletitled, Improved Treatment of Breast Cancer with Anti-HER2 Therapy Requires Interleukin-21 Signaling in CD8+ T Cells
Open the PDF for Improved Treatment of Breast Cancer with Anti-HER2 Therapy Requires Interleukin-21 Signaling in CD8+ T Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 4301: Endothelial angiopoietin-2 expression correlates with tumor angiogenesis and response to sunitinib in metastatic renal cell carcinoma

Anita Lampinen, Juhana Rautiola, Tuomas Mirtti, Ari Ristimäki, Heikki Joensuu, Petri Bono, Pipsa Saharinen
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4301.
https://doi.org/10.1158/1538-7445.AM2015-4301
Published: 01 August 2015
View articletitled, Abstract 4301: Endothelial angiopoietin-2 expression correlates with tumor angiogenesis and response to sunitinib in metastatic renal cell carcinoma
Journal Articles

Abstract P5-19-07: Randomized Phase II trial of afatinib alone or with vinorelbine versus investigator's choice of treatment in patients with HER2-positive breast cancer with progressive brain metastases after trastuzumab and/or lapatinib-based therapy: LUX-Breast 3

Javier Cortés, Veronique Dieras, Jungsil Ro, Jérôme Barriere, Thomas Bachelot, Sara Hurvitz, Emilie Le Rhun, Marc Espie, Sung-Bae Kim, Andreas Schneeweiss, Joo Hyuk Sohn, Jean-Marc Nabholtz, Pirkko-Liisa Kellokumpu-Lehtinen, Julie Taguchi, Federico Piacentini, Eva Ciruelos, Petri Bono, Mahmoud Ould-Kaci, Flavien Roux, Heikki Joensuu
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P5-19-07.
https://doi.org/10.1158/1538-7445.SABCS14-P5-19-07
Published: 01 May 2015
View articletitled, Abstract P5-19-07: Randomized Phase II trial of afatinib alone or with vinorelbine versus investigator's choice of treatment in patients with HER2-positive breast cancer with progressive brain metastases after trastuzumab and/or lapatinib-based therapy: LUX-Breast 3
Journal Articles

Abstract P5-02-01: Comparison of ESR1, PGR, HER2 and KI67 expression by central IHC and MammaTyper® RT-qPCR kit in the FinHer trial

Ralph M Wirtz, Pirkko-Liisa Kellokumpu-Lehtinen, Jorma Isola, Vesa Kataja, Petri Bono, Taina Turpeenniemi-Hujanen, Sirkuu Jyrkkiö, Harri Sitho, Sebastian Eidt, Ugur Sahin, Heikki Joensuu
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P5-02-01.
https://doi.org/10.1158/1538-7445.SABCS14-P5-02-01
Published: 01 May 2015
View articletitled, Abstract P5-02-01: Comparison of ESR1, PGR, HER2 and KI67 expression by central IHC and MammaTyper® RT-qPCR kit in the FinHer trial
Journal Articles

Abstract P3-06-03: Quantitative p95HER2 and HER2 correlations with outcome in the FinHer trial

Jeff Sperinde, Weidong Huang, Aki Vehtari, Ahmed Chenna, Pirkko-Liisa Kellokumpu-Lehtinen, John Winslow, Petri Bono, Yolanda Lie, Jodi Weidler, Heikki Joensuu
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P3-06-03.
https://doi.org/10.1158/1538-7445.SABCS14-P3-06-03
Published: 01 May 2015
View articletitled, Abstract P3-06-03: Quantitative p95HER2 and HER2 correlations with outcome in the FinHer trial
Journal Articles

Early Pregnancy Sex Steroids and Maternal Breast Cancer: A Nested Case–Control Study

Renée T. Fortner, Helena Schock, Rudolf Kaaks, Matti Lehtinen, Eero Pukkala, Hans-Åke Lakso, Minna Tanner, Raija Kallio, Heikki Joensuu, Kjell Grankvist, Anne Zeleniuch-Jacquotte, Paolo Toniolo, Eva Lundin, Helja-Marja Surcel
Journal: Cancer Research
Cancer Res (2014) 74 (23): 6958–6967.
https://doi.org/10.1158/0008-5472.CAN-14-2150
Published: 30 November 2014
View articletitled, Early Pregnancy Sex Steroids and Maternal Breast Cancer: A Nested Case–Control Study
Open the PDF for Early Pregnancy Sex Steroids and Maternal Breast Cancer: A Nested Case–Control Study in another window
Includes: Supplementary data