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Journal Articles

Modulation of Macropinocytosis-Mediated Internalization Decreases Ocular Toxicity of Antibody–Drug Conjugates

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Hui Zhao, John Atkinson, Sara Gulesserian, Zhilan Zeng, Jenny Nater, Jimmy Ou, Peng Yang, Karen Morrison, Jeffrey Coleman, Faisal Malik, Pia Challita-Eid, Sher Karki, Hector Aviña, René Hubert, Linnette Capo, Josh Snyder, Sung-Ju Moon, Roland Luethy, Brian A. Mendelsohn, David R. Stover, Fernando Doñate
Journal: Cancer Research
Cancer Res (2018) 78 (8): 2115–2126.
https://doi.org/10.1158/0008-5472.CAN-17-3202
Published: 12 April 2018
View articletitled, Modulation of Macropinocytosis-Mediated Internalization Decreases Ocular Toxicity of Antibody–Drug Conjugates
Open the PDF for Modulation of Macropinocytosis-Mediated Internalization Decreases Ocular Toxicity of Antibody–Drug Conjugates in another window
Includes: Supplementary data
Journal Articles

Abstract 2709: Evaluation of CD37 expression and binding of AGS67E, an antibody-drug conjugate (ADC) against CD37, on white blood cells (WBCs) collected from phase I non-Hodgkin lymphoma (NHL) patients

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Sher Karki, Hector Avina, Jacqueline Lackey, Ahmed Sawas, Kerry J. Savage, Raymond Perez, Ranjana Advani, Jasmine Zain, Owen A. O'Connor, Sara Gulesserian, Hui Zhao, Peng Yang, Karen Morrison, Leonard Reyno, Fernando Donate
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2709.
https://doi.org/10.1158/1538-7445.AM2017-2709
Published: 01 July 2017
View articletitled, Abstract 2709: Evaluation of CD37 expression and binding of AGS67E, an antibody-drug conjugate (ADC) against CD37, on white blood cells (WBCs) collected from phase I non-Hodgkin lymphoma (NHL) patients
Journal Articles

Abstract 574: AGS62P1, a novel site-specific antibody drug conjugate targeting FLT3 exhibits potent anti-tumor activity regardless of FLT3 kinase activation status

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Nandini Rudra-Ganguly, Pia M. Challita-Eid, Christine Lowe, Mike Mattie, Sung-Ju Moon, Brian A. Mendelsohn, Monica Leavitt, Cyrus Virata, Alla Verlinsky, Linnette Capo, Mi Sook Chang, Deanna L. Russell, Baljinder Randhawa, Gao Liu, René Hubert, Mary Brodey, Hector Aviña, Chunying Zhang, Joseph D. Abad, Banmeet Anand, Sher Karki, Zili An, Roland Luethy, Fernando Doñate, Daniel S. Pereira, Kendall Morrison, Ingrid B.J. Joseph, David R. Stover
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 574.
https://doi.org/10.1158/1538-7445.AM2016-574
Published: 15 July 2016
View articletitled, Abstract 574: AGS62P1, a novel site-specific antibody drug conjugate targeting FLT3 exhibits potent anti-tumor activity regardless of FLT3 kinase activation status
Journal Articles

Enfortumab Vedotin Antibody–Drug Conjugate Targeting Nectin-4 Is a Highly Potent Therapeutic Agent in Multiple Preclinical Cancer Models

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Pia M. Challita-Eid, Daulet Satpayev, Peng Yang, Zili An, Karen Morrison, Yuriy Shostak, Arthur Raitano, Rossana Nadell, Wendy Liu, Dawn Ratay Lortie, Linnette Capo, Alla Verlinsky, Monica Leavitt, Faisal Malik, Hector Aviña, Claudia I. Guevara, Nick Dinh, Sher Karki, Banmeet S. Anand, Daniel S. Pereira, Ingrid B.J. Joseph, Fernando Doñate, Kendall Morrison, David R. Stover
Journal: Cancer Research
Series: Author Choice
Cancer Res (2016) 76 (10): 3003–3013.
https://doi.org/10.1158/0008-5472.CAN-15-1313
Published: 12 May 2016
View articletitled, Enfortumab Vedotin Antibody–Drug Conjugate Targeting Nectin-4 Is a Highly Potent Therapeutic Agent in Multiple Preclinical Cancer Models
Open the PDF for Enfortumab Vedotin Antibody–Drug Conjugate Targeting Nectin-4 Is a Highly Potent Therapeutic Agent in Multiple Preclinical Cancer Models in another window
Includes: Supplementary data
Journal Articles

Abstract 2650: Ags67e, an anti-cd37 monomethyl auristatin e antibody (mmae) drug conjugate as a potential therapeutic for non-hodgkin's lymphoma, chronic lymphocytic leukemia and acute myeloid leukemia

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Daniel S. Pereira, Claudia Guevara, Alla Verlinsky, Cyrus Virata, J Hsu Ssucheng, Zili An, Chungying Zhang, Nick Dinh, Hector Avina, Lisa Do, Sher Karki, Joseph Abad, Peng Yang, Jimmy Ou, Karen Morrison, Sing-Ju Moon, Faisal Malik, Liqing Jin, Michael Choi, Christina Wu, Banmeet Anand, Scott Cooper, Ingrid Joseph, Xiao-Chi Jia, Kendall Morrison, Pia Challita-Eid, Fernando Donate, Thomas Kipps, John Dick, David Stover
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2650.
https://doi.org/10.1158/1538-7445.AM2014-2650
Published: 01 October 2014
View articletitled, Abstract 2650: Ags67e, an anti-cd37 monomethyl auristatin e antibody (mmae) drug conjugate as a potential therapeutic for non-hodgkin's lymphoma, chronic lymphocytic leukemia and acute myeloid leukemia
Journal Articles

Abstract 2832: Development of AGS-22M6E, a novel antibody drug conjugate (ADC) targeting Nectin-4 for the treatment of solid tumors

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Daulet Satpayev, Michael Torgov, Peng Yang, Karen Morrison, Yuriy Shostak, Art Raitano, Wendy Liu, Dawn Lortie, Zili An, Linnette Capo, Monica Leavitt, Myra Perez, Alla Verlinsky, Kenna Shirasuna, Hector Avina, Claudia Guevara, Kendall Morrison, Pia Challita-Eid, Xiao-Chi Jia, Jean Gudas, David Stover
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2832.
https://doi.org/10.1158/1538-7445.AM2011-2832
Published: 15 April 2011
View articletitled, Abstract 2832: Development of AGS-22M6E, a novel antibody drug conjugate (ADC) targeting Nectin-4 for the treatment of solid tumors
Journal Articles

Abstract 4566: AGS-1C4D4: A fully human anti-PSCA antibody inhibits tumor formation and metastasis in orthotopic models of pancreatic cancer

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Tony Navas, Trisha Haubrich, Jenny Llamas, Hector Avina, Zhang Chunying, Myra Perez, Linnette Capo, Monica Leavitt, Rou-Yu Chen, Alla Verlinsky, Zili An, James Secrest, Nandini Ganguly, Daulet Satpayev, Karen Morrison, Art Raitano, Pia Challita-Eid, Xiao-Chi Jia, Kendall Morrison, Alan Hartford, David Stover
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4566.
https://doi.org/10.1158/1538-7445.AM2011-4566
Published: 15 April 2011
View articletitled, Abstract 4566: AGS-1C4D4: A fully human anti-PSCA antibody inhibits tumor formation and metastasis in orthotopic models of pancreatic cancer