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Harry van Steeg
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Journal Articles

Abstract 2550: Expanded simple tandem repeat (ESTR) mutations in offspring of benzo(a)pyrene exposed DNA repair deficient male mice

Roger Godschalk, Nicole Verhofstad, Joost Linschooten, Jan Van Benthem, Harry Van Steeg, Carole Yauk, Frederik-Jan Van Schooten
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2550.
https://doi.org/10.1158/1538-7445.AM2012-2550
Published: 15 April 2012
View articletitled, Abstract 2550: Expanded simple tandem repeat (ESTR) mutations in offspring of benzo(a)pyrene exposed DNA repair deficient male mice
Journal Articles

Mouse Models for the p53 R72P Polymorphism Mimic Human Phenotypes

Feng Zhu, Martijn E.T. Dollé, Thomas R. Berton, Raoul V. Kuiper, Carrie Capps, Alexsandra Espejo, Mark J. McArthur, Mark T. Bedford, Harry van Steeg, Annemieke de Vries, David G. Johnson
Journal: Cancer Research
Cancer Res (2010) 70 (14): 5851–5859.
https://doi.org/10.1158/0008-5472.CAN-09-4646
Published: 14 July 2010
View articletitled, Mouse Models for the p53 R72P Polymorphism Mimic Human Phenotypes
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Includes: Supplementary data
Journal Articles

Abstract 1875: Dietary grape seed proanthocyanidins induce rapid repair of DNA damage via nucleotide excision repair genes in preventing UV-induced immunosuppression

Santosh K. Katiyar, Harry van Steeg, Som D. Sharma
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1875.
https://doi.org/10.1158/1538-7445.AM10-1875
Published: 15 April 2010
View articletitled, Abstract 1875: Dietary grape seed proanthocyanidins induce rapid repair of DNA damage via nucleotide excision repair genes in preventing UV-induced immunosuppression
Journal Articles

Administration of green tea polyphenols in drinking water inhibits UV-induced skin tumor development through IL-12-mediated enhancement of nucleotide excision repair genes in mice

Santosh Katiyar, Syed Meeran, Nandan Katiyar, Harry van Steeg, Suhail Akhtar
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2117.
Published: 01 May 2008
View articletitled, Administration of green tea polyphenols in drinking water inhibits UV-induced skin tumor development through IL-12-mediated enhancement of nucleotide excision repair genes in mice
Journal Articles

Mouse Models for Xeroderma Pigmentosum Group A and Group C Show Divergent Cancer Phenotypes

Joost P.M. Melis, Susan W.P. Wijnhoven, Rudolf B. Beems, Marianne Roodbergen, Jolanda van den Berg, Hojin Moon, Errol Friedberg, Gijsbertus T.J. van der Horst, Jan H.J. Hoeijmakers, Jan Vijg, Harry van Steeg
Journal: Cancer Research
Cancer Res (2008) 68 (5): 1347–1353.
https://doi.org/10.1158/0008-5472.CAN-07-6067
Published: 03 March 2008
View articletitled, Mouse Models for Xeroderma Pigmentosum Group A and Group C Show Divergent Cancer Phenotypes
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Journal Articles

Dominant-Negative but not Gain-of-Function Effects of a p53.R270H Mutation in Mouse Epithelium Tissue after DNA Damage

Susan W.P. Wijnhoven, Ewoud N. Speksnijder, Xiaoling Liu, Edwin Zwart, Conny Th. M. vanOostrom, Rudolf B. Beems, Esther M. Hoogervorst, Mirjam M. Schaap, Laura D. Attardi, Tyler Jacks, Harry van Steeg, Jos Jonkers, Annemieke de Vries
Journal: Cancer Research
Cancer Res (2007) 67 (10): 4648–4656.
https://doi.org/10.1158/0008-5472.CAN-06-4681
Published: 17 May 2007
View articletitled, Dominant-Negative but not Gain-of-Function Effects of a p53.R270H Mutation in Mouse Epithelium Tissue after DNA Damage
Open the PDF for Dominant-Negative but not Gain-of-Function Effects of a p53.R270H Mutation in Mouse Epithelium Tissue after DNA Damage in another window
Includes: Supplementary data
Journal Articles

Human DNA repair disorders and mouse models

Jan Hoeijmakers, Ingrid van der Pluijm, George Garinis, Laura Niedernhofer, Karin Diderich, Astrid Lalai, James Mitchell, Rudolf Beems, Harry van Steeg, Gijsbertus van der Horst
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): SY28-02.
Published: 01 May 2007
View articletitled, Human DNA repair disorders and mouse models
Journal Articles

Mice Expressing a Mammary Gland–Specific R270H Mutation in the p53 Tumor Suppressor Gene Mimic Human Breast Cancer Development

Susan W.P. Wijnhoven, Edwin Zwart, Ewoud N. Speksnijder, Rudolf B. Beems, Kenneth P. Olive, David A. Tuveson, Jos Jonkers, Mirjam M. Schaap, Jolanda van den Berg, Tyler Jacks, Harry van Steeg, Annemieke de Vries
Journal: Cancer Research
Cancer Res (2005) 65 (18): 8166–8173.
https://doi.org/10.1158/0008-5472.CAN-05-1650
Published: 15 September 2005
View articletitled, Mice Expressing a Mammary Gland–Specific R270H Mutation in the p53 Tumor Suppressor Gene Mimic Human Breast Cancer Development
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Journal Articles

Lack of p53 Ser389 Phosphorylation Predisposes Mice to Develop 2-Acetylaminofluorene–Induced Bladder Tumors but not Ionizing Radiation–Induced Lymphomas

Esther M. Hoogervorst, Wendy Bruins, Edwin Zwart, Conny Th.M. van Oostrom, Gerard J. van den Aardweg, Rudolf B. Beems, Jolanda van den Berg, Tyler Jacks, Harry van Steeg, Annemieke de Vries
Journal: Cancer Research
Cancer Res (2005) 65 (9): 3610–3616.
https://doi.org/10.1158/0008-5472.CAN-04-4328
Published: 02 May 2005
View articletitled, Lack of p53 Ser389 Phosphorylation Predisposes Mice to Develop 2-Acetylaminofluorene–Induced Bladder Tumors but not Ionizing Radiation–Induced Lymphomas
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Includes: Supplementary data
Journal Articles

p53 Heterozygosity Results in an Increased 2-Acetylaminofluorene-Induced Urinary Bladder but not Liver Tumor Response in DNA Repair-Deficient Xpa Mice

Esther M. Hoogervorst, Conny Th. M. van Oostrom, Rudolf B. Beems, Jan van Benthem, Siska Gielis, Jolanda P. Vermeulen, Piet W. Wester, Joseph G. Vos, Annemieke de Vries, Harry van Steeg
Journal: Cancer Research
Cancer Res (2004) 64 (15): 5118–5126.
https://doi.org/10.1158/0008-5472.CAN-04-0350
Published: 02 August 2004
View articletitled, p53 Heterozygosity Results in an Increased 2-Acetylaminofluorene-Induced Urinary Bladder but not Liver Tumor Response in DNA Repair-Deficient Xpa Mice
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Journal Articles

Suppression of UV Carcinogenesis by Difluoromethylornithine in Nucleotide Excision Repair-deficient Xpa Knockout Mice

Heggert Rebel, Harry van Steeg, Rudolf B. Beems, Ron Schouten, Frank R. de Gruijl, Carrol Terleth
Journal: Cancer Research
Cancer Res (2002) 62 (5): 1338–1342.
Published: 01 March 2002
View articletitled, Suppression of UV Carcinogenesis by Difluoromethylornithine in Nucleotide Excision Repair-deficient Xpa Knockout Mice
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Journal Articles

Early p53-positive Foci as Indicators of Tumor Risk in Ultraviolet-exposed Hairless Mice: Kinetics of Induction, Effects of DNA Repair Deficiency, and p53 Heterozygosity

Heggert Rebel, Laurent O. Mosnier, Rob J. W. Berg, Anja Westerman-de Vries, Harry van Steeg, Henk J. van Kranen, Frank R. de Gruijl
Journal: Cancer Research
Cancer Res (2001) 61 (3): 977–983.
Published: 02 February 2001
View articletitled, Early p53-positive Foci as Indicators of Tumor Risk in Ultraviolet-exposed Hairless Mice: Kinetics of Induction, Effects of DNA Repair Deficiency, and p53 Heterozygosity
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Journal Articles

The Relationship between Benzo[a]pyrene-induced Mutagenesis and Carcinogenesis in Repair-deficient Cockayne Syndrome Group B Mice

Susan W. P. Wijnhoven, Hanneke J. M. Kool, Conny T. M. van Oostrom, Rudolf B. Beems, Leon H. F. Mullenders, Albert A. van Zeeland, Gijsbertus T. J. van der Horst, Harry Vrieling, Harry van Steeg
Journal: Cancer Research
Cancer Res (2000) 60 (20): 5681–5687.
Published: 15 October 2000
View articletitled, The Relationship between Benzo[a]pyrene-induced Mutagenesis and Carcinogenesis in Repair-deficient Cockayne Syndrome Group B Mice
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Journal Articles

Mouse Model for the DNA Repair/Basal Transcription Disorder Trichothiodystrophy Reveals Cancer Predisposition

Jan de Boer, Harry van Steeg, Rob J. W. Berg, Johan Garssen, Jan de Wit, Conny T. M. van Oostrum, Rudolph B. Beems, GijsbertusT. J. van der Horst, Coen F. van Kreijl, Frank R. de Gruijl, Dirk Bootsma, Jan H. J. Hoeijmakers, Geert Weeda
Journal: Cancer Research
Cancer Res (1999) 59 (14): 3489–3494.
Published: 15 July 1999
View articletitled, Mouse Model for the DNA Repair/Basal Transcription Disorder Trichothiodystrophy Reveals Cancer Predisposition
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Journal Articles

Elevated Frequencies of Benzo(a)pyrene-induced Hprt Mutations in Internal Tissue of XPA-deficient Mice

Sandra A. M. Bol, Harry van Steeg, Jacob G. Jansen, Conny Van Oostrom, Annemieke de Vries, Anton J. L. de Groot, Ad D. Tates, Harry Vrieling, Albert A. van Zeeland, Leon H. F. Mullenders
Journal: Cancer Research
Cancer Res (1998) 58 (13): 2850–2856.
Published: 01 July 1998
View articletitled, Elevated Frequencies of Benzo(a)pyrene-induced Hprt Mutations in Internal Tissue of XPA-deficient Mice
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Journal Articles

A Lack of Radiation-induced Ornithine Decarboxylase Activity Prevents Enhanced Reactivation of Herpes Simplex Virus and Is Linked to Non-Cancer Proneness in Xeroderma Pigmentosum Patients

Carrol Terleth, Theo van Laar, Ron Schouten, Harry van Steeg, Hennie Hodemaekers, Thera Wormhoudt, Paulien D. M. Cornelissen-Steijger, Peter J. Abrahams, Alex J. van der Eb
Journal: Cancer Research
Cancer Res (1997) 57 (19): 4384–4392.
Published: 01 October 1997
View articletitled, A Lack of Radiation-induced Ornithine Decarboxylase Activity Prevents Enhanced Reactivation of Herpes Simplex Virus and Is Linked to Non-Cancer Proneness in Xeroderma Pigmentosum Patients
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Journal Articles

Relative Susceptibilities of XPA Knockout Mice and Their Heterozygous and Wild-Type Littermates to UVB-induced Skin Cancer

Rob J. W. Berg, Annemieke de Vries, Harry van Steeg, Frank R. de Gruijl
Journal: Cancer Research
Cancer Res (1997) 57 (4): 581–584.
Published: 01 February 1997
View articletitled, Relative Susceptibilities of XPA Knockout Mice and Their Heterozygous and Wild-Type Littermates to UVB-induced Skin Cancer
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