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Journal Articles

m6A Modification Promotes EMT and Metastasis of Castration-Resistant Prostate Cancer by Upregulating NFIB

Feng Shu, Hao Liu, Xiaohui Chen, Ye Liu, Jiangli Zhou, Lei Tang, Wanwei Cao, Shanshan Yang, Yili Long, Rongna Li, Hao Wang, Hongsheng Wang, Guanmin Jiang
Journal: Cancer Research
Cancer Res (2024) 84 (12): 1947–1962.
https://doi.org/10.1158/0008-5472.CAN-23-1954
Published: 14 June 2024
View article titled, m<sup>6</sup>A Modification Promotes EMT and Metastasis of Castration-Resistant Prostate Cancer by Upregulating NFIB
Open the PDF for m<sup>6</sup>A Modification Promotes EMT and Metastasis of Castration-Resistant Prostate Cancer by Upregulating NFIB in another window
Includes: Supplementary data
Journal Articles

Abstract PO1-01-04: The optimal neoadjuvant treatment regimen for HR+/HER2+ breast cancer: a network meta-analysis

Hao Wang, Shiwei Liu, Miao Yu, Kun Mi, Exian Mou, Li Xia, Weimin Xie, Hao Tang, Yajing Feng, Xin Yu
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO1-01-04.
https://doi.org/10.1158/1538-7445.SABCS23-PO1-01-04
Published: 02 May 2024
View article titled, Abstract PO1-01-04: The optimal neoadjuvant treatment regimen for HR+/HER2+ breast cancer: a network meta-analysis
Journal Articles

Abstract PO5-21-09: Clinical outcomes by age subgroups in the phase 3 TROPiCS-02 study of sacituzumab govitecan vs treatment of physician’s choice in HR+/HER2‒ metastatic breast cancer

Aditya Bardia, Peter Schmid, Sara Tolaney, Frederik Marmé, Javier Cortés, Theresa Valdez, Hao Wang, Wendy Verret, Hope Rugo
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO5-21-09.
https://doi.org/10.1158/1538-7445.SABCS23-PO5-21-09
Published: 02 May 2024
View article titled, Abstract PO5-21-09: Clinical outcomes by age subgroups in the phase 3 TROPiCS-02 study of sacituzumab govitecan vs treatment of physician’s choice in HR+/HER2‒ metastatic breast cancer
Journal Articles

Abstract CT134: Safety and immunologic impact of neoadjuvant/adjuvant GM-CSF-secreting allogenic pancreatic tumor cell vaccine (GVAX) combined with cyclophosphamide, pembrolizumab, and macrophage-targeting CSF1R inhibitor IMC-CS4 in pancreatic adenocarcinoma

Arielle Urman, Yingjun Ding, Hao Wang, Richard A. Burkhart, Jin He, Elizabeth M. Jaffee, Amol K. Narang, Dung Le, Daniel A. Laheru, Lei Zheng, Ana De Jesus-Acosta
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): CT134.
https://doi.org/10.1158/1538-7445.AM2024-CT134
Published: 05 April 2024
View article titled, Abstract CT134: Safety and immunologic impact of neoadjuvant/adjuvant GM-CSF-secreting allogenic pancreatic tumor cell vaccine (GVAX) combined with cyclophosphamide, pembrolizumab, and macrophage-targeting CSF1R inhibitor IMC-CS4 in pancreatic adenocarcinoma
Journal Articles

Abstract LB208: An intricate connection between canonical Wnt and MAPK/ERK signaling drives the partial hybrid EMT state involving FOXC2/p63 activation leading to cancer stemness and metastasis

Huizhi Liang, Outhiriaradjou Benard, Zuen Ren, Kimita Suyama, Jingli Wang, Anthony Griffen, Hao Wang, Lindsay LeFave, Larry Norton, Rachel B. Hazan
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): LB208.
https://doi.org/10.1158/1538-7445.AM2024-LB208
Published: 05 April 2024
View article titled, Abstract LB208: An intricate connection between canonical Wnt and MAPK/ERK signaling drives the partial hybrid EMT state involving FOXC2/p63 activation leading to cancer stemness and metastasis
Journal Articles

Abstract CT007: Phase 1/2 trial of copanlisib in combination with nivolumab for microsatellite stable (MSS) colorectal cancer (CRC)

Eric S. Christenson, Jeremiah A. Wala, Rose Parkinson, Natalie B. Collins, Christopher Jakubowski, Jea-Ren Lin, Hao Wang, Won Jin Ho, Sabrina Chan, Rachel Klein, Yvette Cetasaan, Emma Johnson, Maureen Berg, Jeffrey Meyerhardt, Benjamin Schlechter, Harshabad Singh, Peter K. Sorger, Marios Giannakis, Nilofer Azad
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): CT007.
https://doi.org/10.1158/1538-7445.AM2024-CT007
Published: 05 April 2024
View article titled, Abstract CT007: Phase 1/2 trial of copanlisib in combination with nivolumab for microsatellite stable (MSS) colorectal cancer (CRC)
Journal Articles

Abstract CT056: Development of a novel next-generation RET inhibitor

Jun Zhong, Ruxue Xiao, Wenya Xie, Minchun Chen, Xiaohu Chen, Hao Wang, Yongbo Liu, Qin Gao, Xiupeng Wang, Zongbao Wang, Qian Chen, Jing Yang, Yizhe Ji, Yuxun Wang
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): CT056.
https://doi.org/10.1158/1538-7445.AM2024-CT056
Published: 05 April 2024
View article titled, Abstract CT056: Development of a novel next-generation RET inhibitor
Journal Articles

Abstract CT022: Mutant KRAS peptide-based vaccine in patients at high risk of developing pancreatic cancer: Preliminary analysis from a phase I study

Saurav D. Haldar, Amanda Huff, Elizabeth Abou Diwan, Anna Ferguson, Carol Judkins, Jiayun Lu, Hao Wang, Hassan Sinan, Christopher Thoburn, Katherine M. Bever, Mark Yarchoan, Amy M. Thomas, Julie M. Nauroth, Daniel A. Laheru, Michael G. Goggins, Elizabeth M. Jaffee, Nilofer S. Azad, Neeha Zaidi
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): CT022.
https://doi.org/10.1158/1538-7445.AM2024-CT022
Published: 05 April 2024
View article titled, Abstract CT022: Mutant KRAS peptide-based vaccine in patients at high risk of developing pancreatic cancer: Preliminary analysis from a phase I study
Journal Articles

Abstract 2144: Disparities in gynecologic cancer survival outcome by treatment facility and region

Sejong Bae, Vishruti Pandya, Chenguang Wang, Hao Wang, Rebecca C. Arend, Charles A. Leath, Warner K. Huh
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2144.
https://doi.org/10.1158/1538-7445.AM2024-2144
Published: 22 March 2024
View article titled, Abstract 2144: Disparities in gynecologic cancer survival outcome by treatment facility and region
Journal Articles

Abstract 406: Characterization of whole genome duplication in a genomic cohort of over 14000 cell free DNA samples

Andrew Gross, Hao Wang, Denis Tolkunov, Colby Jenkins, Sara Wienke, Catalin Barbacioru, Han-Yu Chuang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 406.
https://doi.org/10.1158/1538-7445.AM2024-406
Published: 22 March 2024
View article titled, Abstract 406: Characterization of whole genome duplication in a genomic cohort of over 14000 cell free DNA samples
Journal Articles

Abstract 2661: Identification of a novel morphology of tertiary lymphoid structure in patients with hepatocellular carcinoma treated with neoadjuvant immune checkpoint blockade

Daniel H. Shu, Won Jin Ho, Luciane T. Kagohara, Alexander Girgis, Sarah M. Shin, Ludmila Danilova, Jae W. Lee, Dimitrios N. N. Sidiropoulos, Sarah Mitchell, Kabeer Munjal, Kathryn Howe, Kayla J. Bendinelli, Hanfei Qi, Guanglan Mo, Janelle Montagne, Tamara Y. Lopez-Vidal, Qingfeng Zhu, Amanda L. Huff, Xuan Yuan, Alexei Hernandez, Erin M. Coyne, Neeha Zaidi, Daniel J. Zabransky, Logan L. Engle, Aleksandra Ogurtsova, Marina Baretti, Daniel Laheru, Jennifer N. Durham, Hao Wang, Robert Anders, Elizabeth M. Jaffee, Elana J. Fertig, Mark Yarchoan
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2661.
https://doi.org/10.1158/1538-7445.AM2024-2661
Published: 22 March 2024
View article titled, Abstract 2661: Identification of a novel morphology of tertiary lymphoid structure in patients with hepatocellular carcinoma treated with neoadjuvant immune checkpoint blockade
Journal Articles

Abstract A044: Tumor-infiltrating lymphocyte density correlates with survival in pancreatic adenosquamous carcinoma

Saurav D. Haldar, Christopher D. Jakubowski, Su Jin Lim, Hao Wang, Richard A. Burkhart, Kelly Lafaro, William R. Burns, III, Jin He, Daniel A. Laheru, Elizabeth D. Thompson, Nilofer S. Azad
Journal: Cancer Research
Cancer Res (2024) 84 (2_Supplement): A044.
https://doi.org/10.1158/1538-7445.PANCA2023-A044
Published: 16 January 2024
View article titled, Abstract A044: Tumor-infiltrating lymphocyte density correlates with survival in pancreatic adenosquamous carcinoma
Journal Articles

Abstract CT036: Safety and immunogenicity of a first-in-human mutant KRAS long peptide vaccine combined with ipilimumab/nivolumab in resected pancreatic cancer: Preliminary analysis from a phase I study

Saurav D. Haldar, Amanda Huff, Thatcher R. Heumann, Maureen Berg, Anna Ferguson, Su Jin Lim, Hao Wang, Amy M. Thomas, Julie M. Nauroth, Marina Baretti, Katherine M. Bever, Mark Yarchoan, Daniel A. Laheru, Elizabeth M. Jaffee, Nilofer S. Azad, Neeha Zaidi
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): CT036.
https://doi.org/10.1158/1538-7445.AM2023-CT036
Published: 14 April 2023
View article titled, Abstract CT036: Safety and immunogenicity of a first-in-human mutant KRAS long peptide vaccine combined with ipilimumab/nivolumab in resected pancreatic cancer: Preliminary analysis from a phase I study
Journal Articles

Abstract CT189: A phase I study of BAT1006, a novel anti-HER2 antibody, in patients with locally advanced/metastatic solid tumors

Xingxing Mei, Weijia Tang, Shuqiang Song, Hao Wang, Chuanqi Cao, Cuiying Feng, Bert E. Thomas, Shengfeng Li, Jin-Chen Yu
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): CT189.
https://doi.org/10.1158/1538-7445.AM2023-CT189
Published: 14 April 2023
View article titled, Abstract CT189: A phase I study of BAT1006, a novel anti-HER2 antibody, in patients with locally advanced/metastatic solid tumors
Journal Articles

Abstract 1600: Phase I trial of intravenous mistletoe extract in advanced cancer

Channing J. Paller, Lin Wang, Wei Fu, Rajedra Kumar, Jennifer Durham, Nilofer Azad, Daniel Laheru, Ilene Browner, Sushant Kachhap, Kavya Boyapati, Thomas Odeny, Deborah Armstrong, Christian Meyer, Stephanie Gaillard, Julie Brahmer, Ivelisse Page, Hao Wang, Luis A. Diaz
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1600.
https://doi.org/10.1158/1538-7445.AM2023-1600
Published: 04 April 2023
View article titled, Abstract 1600: Phase I trial of intravenous mistletoe extract in advanced cancer
Journal Articles

Abstract 3241: Single-cell RNA and TCR sequencing of tumor infiltrating lymphocytes identifies changes in pancreatic ductal adenocarcinomas following neoadjuvant treatment with combined anti-PD-1 blocking and anti-CD137 agonist therapy

Joseph A. Tandurella, Jacob T. Mitchell, Janelle M. Montagne, Eric Christenson, Qingfeng Zhu, Ludmilla V. Danilova, Alexander V. Favorov, Won J. Ho, Luciane T. Kagohara, Melanie Loth, Su Jin Lim, Rui Zheng, Jessica Gai, Sarah Mitchell, Dimitrios N. Sidiropoulos, Wenpin Hou, Yao Xu, Hao Wang, Jacquelyn W. Zimmerman, Srinivasan Yegnasubramanian, Robert Anders, Elizabeth M. Jaffee, Lei Zheng, Elana J. Fertig
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3241.
https://doi.org/10.1158/1538-7445.AM2023-3241
Published: 04 April 2023
View article titled, Abstract 3241: Single-cell RNA and TCR sequencing of tumor infiltrating lymphocytes identifies changes in pancreatic ductal adenocarcinomas following neoadjuvant treatment with combined anti-PD-1 blocking and anti-CD137 agonist therapy
Journal Articles

Abstract 6601: Analytical validation of a robust integrated genomic and epigenomic liquid biopsy for biomarker discovery, therapy selection, and response monitoring

Tingting Jiang, Indira Wu, Yvonne Kim, Nageswara Alla, Giao Tran, Dustin Ma, Forum Shah, Jun Zhao, Sai Chen, Sante Gnerre, Melis Hazar, Hao Wang, Catalin Barbacioru, Karen Ryall, Ankit Jambusaria, Anupam Chakravarthy, Anthony Zunino, Theresa Pham, Farsheed Ghadiri, Evan Diehl, Benjamin Morck, Arancha Sanchez, Rochelle Dayan, XianXian Liu, Jeffrey Werbin, Jill Lai, Brett Kennedy, Ross Eppler, Justin Odegaard, Han-Yu Chuang, Helmy Eltoukhy
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6601.
https://doi.org/10.1158/1538-7445.AM2023-6601
Published: 04 April 2023
View article titled, Abstract 6601: Analytical validation of a robust integrated genomic and epigenomic liquid biopsy for biomarker discovery, therapy selection, and response monitoring
Journal Articles

Abstract 1228: TCF1 orchestrates the epithelial/mesenchymal hybrid phenotype in basal breast cancer via upregulation of FOXC2 leading to stemness and metastasis

Huizhi Liang, Outhiriaradjou Benard, Kimita Suyama, Zuen Ren, Hao Wang, Larry Norton, Rachel Hazan
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1228.
https://doi.org/10.1158/1538-7445.AM2023-1228
Published: 04 April 2023
View article titled, Abstract 1228: TCF1 orchestrates the epithelial/mesenchymal hybrid phenotype in basal breast cancer via upregulation of FOXC2 leading to stemness and metastasis
Journal Articles

Abstract P3-07-08: Exposure-adjusted incidence rates (EAIRs) of adverse events (AEs) from the phase 3 TROPiCS-02 study of sacituzumab govitecan (SG) vs treatment of physician’s choice (TPC) in HR+/HER2- metastatic breast cancer (MBC)

Sara Tolaney, Peter Schmid, Aditya Bardia, Frederik Marmé, Delphine Loirat, Priyanka Sharma, Hao Wang, Olivia Fu, Wendy Verret, Hope Rugo
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P3-07-08.
https://doi.org/10.1158/1538-7445.SABCS22-P3-07-08
Published: 01 March 2023
View article titled, Abstract P3-07-08: Exposure-adjusted incidence rates (EAIRs) of adverse events (AEs) from the phase 3 TROPiCS-02 study of sacituzumab govitecan (SG) vs treatment of physician’s choice (TPC) in HR+/HER2- metastatic breast cancer (MBC)
Journal Articles

Abstract OT2-10-01: A phase 2, randomized study of magrolimab combination therapy in adult patients with unresectable locally advanced or metastatic triple-negative breast cancer

Natalie Rainey, Rohit Joshi, Joanne Win Yang Chiu, Ann Chen, Hao Wang, Jared Odegard, Michael Howland, Sylvia Adams
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): OT2-10-01.
https://doi.org/10.1158/1538-7445.SABCS22-OT2-10-01
Published: 01 March 2023
View article titled, Abstract OT2-10-01: A phase 2, randomized study of magrolimab combination therapy in adult patients with unresectable locally advanced or metastatic triple-negative breast cancer