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Journal Articles

Arginine Deprivation Induces Quiescence and Confers Vulnerability to Ferroptosis in Colorectal Cancer

Yanyun Lin, Yanhong Zhang, Tianze Huang, Junguo Chen, Guanman Li, Bin Zhang, Liang Xu, Kai Wang, Hui He, Hao Chen, Danling Liu, Shuang Guo, Xiaosheng He, Ping Lan

Cancer Res (2025) 85 (9): 1663–1679.

https://doi.org/10.1158/0008-5472.CAN-24-1940

Published: 02 May 2025

View articletitled, Arginine Deprivation Induces Quiescence and Confers Vulnerability to Ferroptosis in Colorectal Cancer

Includes: Supplementary data

Journal Articles

Abstract 5383: Metabolic profiling of compressed stromal cells in the breast peritumor

Julian Najera, Hao Chen, Scott Howard, Meenal Datta

Cancer Res (2025) 85 (8_Supplement_1): 5383.

https://doi.org/10.1158/1538-7445.AM2025-5383

Published: 21 April 2025

View articletitled, Abstract 5383: Metabolic profiling of compressed stromal cells in the breast peritumor

Journal Articles

Abstract 146: Studying the effect of compressive solid stress on macrophage phenotype and function in the context of glioblastoma

Alice Burchett, Hao Chen, Scott Howard, Meenal Datta

Cancer Res (2025) 85 (8_Supplement_1): 146.

https://doi.org/10.1158/1538-7445.AM2025-146

Published: 21 April 2025

View articletitled, Abstract 146: Studying the effect of compressive solid stress on macrophage phenotype and function in the context of glioblastoma

Journal Articles

DNA of Neutrophil Extracellular Traps Binds TMCO6 to Impair CD8⁺ T-cell Immunity in Hepatocellular Carcinoma

Mengjia Song, Chaoqi Zhang, Shaoyan Cheng, Dijun Ouyang, Yu Ping, Jieying Yang, YaoJun Zhang, Yan Tang, Hao Chen, Qi-jing Wang, Yong-qiang Li, Jia He, Tong Xiang, Yizhuo Zhang, Jian-Chuan Xia

Cancer Res (2024) 84 (10): 1613–1629.

https://doi.org/10.1158/0008-5472.CAN-23-2986

Published: 15 May 2024

View articletitled, DNA of Neutrophil Extracellular Traps Binds TMCO6 to Impair CD8+ T-cell Immunity in Hepatocellular Carcinoma

Includes: Supplementary data

Journal Articles

Abstract PO3-06-13: A novel stable 6-aryl-2-benzoyl-pyridine colchicine-binding site inhibitor targeting microtubules (60c) is effective against taxane-resistant, metastatic breast cancer

Damilola Oluwalana, Kelli Hartman, Raisa Krutilina, Hao Chen, Hilaire Playa, Shanshan Deng, Deanna Parke, Duane Miller, Tiffany Seagroves, Wei Li

Cancer Res (2024) 84 (9_Supplement): PO3-06-13.

https://doi.org/10.1158/1538-7445.SABCS23-PO3-06-13

Published: 02 May 2024

View articletitled, Abstract PO3-06-13: A novel stable 6-aryl-2-benzoyl-pyridine colchicine-binding site inhibitor targeting microtubules (60c) is effective against taxane-resistant, metastatic breast cancer

Journal Articles

Abstract 678: Experimental therapy of triple negative breast cancer with next-generation of MDM2 inhibitors

Wei Wang, Hao Chen, Yang Xie, Sayantap Datta, Wei Li, Ruiwen Zhang

Cancer Res (2024) 84 (6_Supplement): 678.

https://doi.org/10.1158/1538-7445.AM2024-678

Published: 22 March 2024

View articletitled, Abstract 678: Experimental therapy of triple negative breast cancer with next-generation of MDM2 inhibitors

Journal Articles

Abstract 173: Studying the interaction between macrophages and solid stress in novel models of the tumor immune microenvironment

Alice Burchett, Saeed Siri, Hao Chen, Scott Howard, Meenal Datta

Cancer Res (2024) 84 (6_Supplement): 173.

https://doi.org/10.1158/1538-7445.AM2024-173

Published: 22 March 2024

View articletitled, Abstract 173: Studying the interaction between macrophages and solid stress in novel models of the tumor immune microenvironment

Journal Articles

Abstract 1697: Phase separation of BHLHE40 up-regulates SREBF1 and inhibits ferroptosis in pancreatic cancer cells

Yizhi Cao, Xuelong Wang, Yang Liu, Pengyi Liu, Jiejie Qin, Youwei Zhu, Shuyu Zhai, Minmin Shi, Weishen Wang, Xiaxing Deng, Chenghong Peng, Hao Chen, Ruibao Ren, Lingxi Jiang, Baiyong Shen

Cancer Res (2024) 84 (6_Supplement): 1697.

https://doi.org/10.1158/1538-7445.AM2024-1697

Published: 22 March 2024

View articletitled, Abstract 1697: Phase separation of BHLHE40 up-regulates SREBF1 and inhibits ferroptosis in pancreatic cancer cells

Journal Articles

Abstract 1790: Pyruvate carboxylase regulates tumor progression through central carbon metabolism and immunosuppression

Michael F. Coleman, Eylem Kulkoyluoglu Cotul, Alexander J. Pfeil, Alyssa N. Ho, Emily N. Devericks, Muhammad H. Safdar, Hao Chen, Numair Attaar, Violet A. Kiesel, Dorothy Teegarden, Stephen D. Hursting, Michael K. Wendt

Cancer Res (2024) 84 (6_Supplement): 1790.

https://doi.org/10.1158/1538-7445.AM2024-1790

Published: 22 March 2024

View articletitled, Abstract 1790: Pyruvate carboxylase regulates tumor progression through central carbon metabolism and immunosuppression

Journal Articles

Genomic and Evolutionary Characterization of Concurrent Intraductal Carcinoma and Adenocarcinoma of the Prostate

Cancer Res (2024) 84 (1): 154–167.

https://doi.org/10.1158/0008-5472.CAN-23-1176

Published: 02 January 2024

View articletitled, Genomic and Evolutionary Characterization of Concurrent Intraductal Carcinoma and Adenocarcinoma of the Prostate

Includes: Supplementary data

Journal Articles

Abstract LB158: Rapid cancer cell perineural invasion utilizes amoeboid migration

Qi Wang, Andrea Marcadis, Elizabeth Kao, Chun-Hao Chen, Laxmi Gusain, Ann Powers, Richard Bakst, Sylvie Deborde, Richard J. Wong

Cancer Res (2023) 83 (8_Supplement): LB158.

https://doi.org/10.1158/1538-7445.AM2023-LB158

Published: 14 April 2023

View articletitled, Abstract LB158: Rapid cancer cell perineural invasion utilizes amoeboid migration

Journal Articles

Abstract 656: Suppression of pyruvate carboxylase drives tumor microenvironment immunosuppression

Michael F. Coleman, Eylem Kulkoyluoglu Cotul, Alexander J. Pfeil, Emily N. Devericks, Muhammad H. Safdar, Hao Chen, Violet A. Kiesel, Dorothy Teegarden, Stephen D. Hursting, Michael K. Wendt

Cancer Res (2023) 83 (7_Supplement): 656.

https://doi.org/10.1158/1538-7445.AM2023-656

Published: 04 April 2023

View articletitled, Abstract 656: Suppression of pyruvate carboxylase drives tumor microenvironment immunosuppression

Journal Articles

Abstract 3736: ZBTB46/FOXA2/HIF1A transcription activator complex promotes MCTP1-regulated neuroendocrine differentiation and epithelial-to-mesenchymal transition

Vu Thuy Dung Phan, Yu-Ching Wen, Wei-Yu Chen, Wei-Hao Chen, Kuo-Ching Jiang, Han-Ru Li, Van Thi Ngoc Tram, Zi-Qing Chen, Wan-Hsin Wang, Yen-Nien Liu

Cancer Res (2023) 83 (7_Supplement): 3736.

https://doi.org/10.1158/1538-7445.AM2023-3736

Published: 04 April 2023

View articletitled, Abstract 3736: ZBTB46/FOXA2/HIF1A transcription activator complex promotes MCTP1-regulated neuroendocrine differentiation and epithelial-to-mesenchymal transition

Journal Articles

Abstract 1670: Sabizabulin shows anti-cancer efficacy in HER2+ breast cancer and novel sabizabulin derivatives overcome paclitaxel-resistance in triple negative breast cancer

Kelli L. Hartman, Raisa I. Krutilina, Damilola Oluwalana, Deanna N. Parke, Hao Chen, Duane D. Miller, Wei Li, Tiffany N. Seagroves

Cancer Res (2023) 83 (7_Supplement): 1670.

https://doi.org/10.1158/1538-7445.AM2023-1670

Published: 04 April 2023

View articletitled, Abstract 1670: Sabizabulin shows anti-cancer efficacy in HER2+ breast cancer and novel sabizabulin derivatives overcome paclitaxel-resistance in triple negative breast cancer

Journal Articles

Abstract 2598: The DACH1 gene is frequently deleted in prostate cancer, restrains prostatic intraepithelial neoplasia, augments DNA damage repair and predicts therapy responses

Cancer Res (2023) 83 (7_Supplement): 2598.

https://doi.org/10.1158/1538-7445.AM2023-2598

Published: 04 April 2023

View articletitled, Abstract 2598: The DACH1 gene is frequently deleted in prostate cancer, restrains prostatic intraepithelial neoplasia, augments DNA damage repair and predicts therapy responses

Journal Articles

Abstract 2594: Alcohol drinking inhibits NOTCH-PAX9 signaling in esophageal squamous epithelial cells

Zhaohui Xiong, Menghan Shi, Shuang Ren, Hao Chen, Jing Li, Caizhi Huang, Yahui Li, Yuning Han, Yong Li, Zheng Sun, Xiaoxin Chen

Cancer Res (2023) 83 (7_Supplement): 2594.

https://doi.org/10.1158/1538-7445.AM2023-2594

Published: 04 April 2023

View articletitled, Abstract 2594: Alcohol drinking inhibits NOTCH-PAX9 signaling in esophageal squamous epithelial cells

Journal Articles

Abstract 3644: Schwann cells reshape tumor cells and cancer associated fibroblasts in pancreatic ductal adenocarcinoma microenvironment

Meilin Xue, Yongsheng Jiang, Lijie Han, Rui Su, Cheng Xiong, Youwei Zhu, Yizhi Cao, Minmin Shi, Jianjun Chen, Baiyong Shen, Lingxi Jiang, Hao Chen

Cancer Res (2022) 82 (12_Supplement): 3644.

https://doi.org/10.1158/1538-7445.AM2022-3644

Published: 15 June 2022

View articletitled, Abstract 3644: Schwann cells reshape tumor cells and cancer associated fibroblasts in pancreatic ductal adenocarcinoma microenvironment

Journal Articles

Abstract 5096: Characteristics of tumor immune microenvironment in patients carrying comutations of DNA damage response pathways in esophageal cancer

Hao Chen, Xihua Xia, Junling Zhang, Yanan Chen, Mengli Huang

Cancer Res (2022) 82 (12_Supplement): 5096.

https://doi.org/10.1158/1538-7445.AM2022-5096

Published: 15 June 2022

View articletitled, Abstract 5096: Characteristics of tumor immune microenvironment in patients carrying comutations of DNA damage response pathways in esophageal cancer

Journal Articles

Abstract 5763: Comprehensive characteristics between genomic alterations and tumor differentiation in Chinese patients with colorectal cancer

Xiaolong Cui, Aigang Ren, Hao Chen, Yaoliang Huo, Yanwu Zeng, Hao Zhang, Meizhen Hu, He Huang, Yuntong Guo

Cancer Res (2022) 82 (12_Supplement): 5763.

https://doi.org/10.1158/1538-7445.AM2022-5763

Published: 15 June 2022

View articletitled, Abstract 5763: Comprehensive characteristics between genomic alterations and tumor differentiation in Chinese patients with colorectal cancer

Journal Articles

Abstract 725: LIFR promotes SUCLG2-dependent castration resistance and neuroendocrine differentiation of prostate cancer

Hsiu-Lien Yeh, Shian-Ren Lin, Kuo-Ching Jiang, Wei-Hao Chen, Yen-Nien Liu

Cancer Res (2021) 81 (13_Supplement): 725.

https://doi.org/10.1158/1538-7445.AM2021-725

Published: 01 July 2021

View articletitled, Abstract 725: LIFR promotes SUCLG2-dependent castration resistance and neuroendocrine differentiation of prostate cancer

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Arginine Deprivation Induces Quiescence and Confers Vulnerability to Ferroptosis in Colorectal Cancer

Abstract 5383: Metabolic profiling of compressed stromal cells in the breast peritumor

Abstract 146: Studying the effect of compressive solid stress on macrophage phenotype and function in the context of glioblastoma

DNA of Neutrophil Extracellular Traps Binds TMCO6 to Impair CD8⁺ T-cell Immunity in Hepatocellular Carcinoma

Abstract PO3-06-13: A novel stable 6-aryl-2-benzoyl-pyridine colchicine-binding site inhibitor targeting microtubules (60c) is effective against taxane-resistant, metastatic breast cancer

Abstract 678: Experimental therapy of triple negative breast cancer with next-generation of MDM2 inhibitors

Abstract 173: Studying the interaction between macrophages and solid stress in novel models of the tumor immune microenvironment

Abstract 1697: Phase separation of BHLHE40 up-regulates SREBF1 and inhibits ferroptosis in pancreatic cancer cells

Abstract 1790: Pyruvate carboxylase regulates tumor progression through central carbon metabolism and immunosuppression

Genomic and Evolutionary Characterization of Concurrent Intraductal Carcinoma and Adenocarcinoma of the Prostate

Abstract LB158: Rapid cancer cell perineural invasion utilizes amoeboid migration

Abstract 656: Suppression of pyruvate carboxylase drives tumor microenvironment immunosuppression

Abstract 3736: ZBTB46/FOXA2/HIF1A transcription activator complex promotes MCTP1-regulated neuroendocrine differentiation and epithelial-to-mesenchymal transition

Abstract 1670: Sabizabulin shows anti-cancer efficacy in HER2+ breast cancer and novel sabizabulin derivatives overcome paclitaxel-resistance in triple negative breast cancer

Abstract 2598: The DACH1 gene is frequently deleted in prostate cancer, restrains prostatic intraepithelial neoplasia, augments DNA damage repair and predicts therapy responses

Abstract 2594: Alcohol drinking inhibits NOTCH-PAX9 signaling in esophageal squamous epithelial cells

Abstract 3644: Schwann cells reshape tumor cells and cancer associated fibroblasts in pancreatic ductal adenocarcinoma microenvironment

Abstract 5096: Characteristics of tumor immune microenvironment in patients carrying comutations of DNA damage response pathways in esophageal cancer

Abstract 5763: Comprehensive characteristics between genomic alterations and tumor differentiation in Chinese patients with colorectal cancer

Abstract 725: LIFR promotes SUCLG2-dependent castration resistance and neuroendocrine differentiation of prostate cancer

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