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Hans-Georg Rammensee
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Journal Articles

Abstract 3556: Immunopeptidomics-guided tumor antigen warehouse design and first clinical application of a personalized peptide vaccine for prostate cancer

Yacine Maringer, Lena Freudenmann, Annika Nelde, Jonas S. Heitmann, Helmut R. Salih, Marissa Dubbelaar, Jörg Hennenlotter, Arnulf Stenzl, Jens Bedke, Hans-Georg Rammensee, Juliane S. Walz
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3556.
https://doi.org/10.1158/1538-7445.AM2022-3556
Published: 15 June 2022
View article titled, Abstract 3556: Immunopeptidomics-guided tumor antigen warehouse design and first clinical application of a personalized peptide vaccine for prostate cancer
Journal Articles

Abstract 3555: Immunopeptidomics-guided tumor antigen warehouse design for peptide-based immunotherapy in head and neck squamous cell carcinomas

Sarah Schroeder, Thorben Gross, Annika Nelde, Marcel Wacker, Jens Bauer, Jonas Rieth, Marissa Dubbelaar, Lena Muehlenbruch, Yacine Maringer, Paul-Stefan Mauz, Martin Sailer, Julia Philipp, Sven Becker, Thomas Breuer, Helmut R. Salih, Hans-Georg Rammensee, Hubert Löwenheim, Juliane S. Walz
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3555.
https://doi.org/10.1158/1538-7445.AM2022-3555
Published: 15 June 2022
View article titled, Abstract 3555: Immunopeptidomics-guided tumor antigen warehouse design for peptide-based immunotherapy in head and neck squamous cell carcinomas
Journal Articles

Abstract 3168: Immunopeptidome-defined acute myeloid leukemia progenitor cell-associated antigens are targeted in vivo by AML patients’ T cells

Annika Nelde, Heiko Schuster, Tatjana Bilich, Jens Bauer, Malte Roerden, Sarah Schroeder, Jonas S. Heitmann, Elke Rücker-Braun, Hans-Georg Rammensee, Helmut R. Salih, Juliane S. Walz
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3168.
https://doi.org/10.1158/1538-7445.AM2022-3168
Published: 15 June 2022
View article titled, Abstract 3168: Immunopeptidome-defined acute myeloid leukemia progenitor cell-associated antigens are targeted in vivo by AML patients’ T cells
Journal Articles

Abstract 1375: The intra-tumoral spatial heterogeneity of T-cell antigens in glioblastoma: An integrated multi-omics approach

Marcel Wacker, Gioele Medici, Marissa Dubbelaar, Jens Bauer, Annika Nelde, Luca Regli, Michael Weller, Helmut R. Salih, Hans-Georg Rammensee, Marian C. Neidert, Juliane S. Walz
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1375.
https://doi.org/10.1158/1538-7445.AM2022-1375
Published: 15 June 2022
View article titled, Abstract 1375: The intra-tumoral spatial heterogeneity of T-cell antigens in glioblastoma: An integrated multi-omics approach
Journal Articles

Abstract CT258: Interim safety and immunogenicity results of a phase I trial evaluating the multi-peptide COVID-19 vaccine candidate CoVac-1 for induction of SARS-CoV-2 T cell immunity in cancer patients with disease- or treatment-related immunoglobulin deficiency

Claudia Tandler, Jonas S. Heitmann, Maddalena Marconato, Yacine Maringer, Monika Denk, Marion Richter, Annika Nelde, Imma Fischer, Markus W. Löffler, Hans-Georg Rammensee, Helmut R. Salih, Juliane S. Walz
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT258.
https://doi.org/10.1158/1538-7445.AM2022-CT258
Published: 15 June 2022
View article titled, Abstract CT258: Interim safety and immunogenicity results of a phase I trial evaluating the multi-peptide COVID-19 vaccine candidate CoVac-1 for induction of SARS-CoV-2 T cell immunity in cancer patients with disease- or treatment-related immunoglobulin deficiency
Journal Articles

Abstract 2008: The oncogenic fusion protein DNAJB1-PRKACA can be actively targeted by peptide-based immunotherapy in fibrolamellar hepatocellular carcinoma

Jens Bauer, Natalie Köhler, Yacine Maringer, Philip Bucher, Tatjana Bilich, Melissa Zwick, Severin Dicks, Annika Nelde, Marissa Dubbelaar, Jonas Scheid, Marcel Wacker, Jonas J. Heitmann, Sarah Schroeder, Jonas Rieth, Monika Denk, Marion Richter, Reinhild Klein, Irina Bonzheim, Julia Luibrand, Ursula Holzer, Martin Ebinger, Ines B. Brecht, Michael Bitzer, Melanie Boerries, Helmut R. Salih, Hans-Georg Rammensee, Stephan Hailfinger, Juliane S. Walz
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2008.
https://doi.org/10.1158/1538-7445.AM2022-2008
Published: 15 June 2022
View article titled, Abstract 2008: The oncogenic fusion protein DNAJB1-PRKACA can be actively targeted by peptide-based immunotherapy in fibrolamellar hepatocellular carcinoma
Journal Articles

Abstract 1991: Characterization of the exome, transcriptome, and immunopeptidome to map alterations in primary and recurrent glioblastoma

Marissa L. Dubbelaar, Lena K. Freudenmann, Jonas Scheid, Julia Velz, Gioele Medici, Konstantina Kapolou, Malte Mohme, Leon Bichmann, Marie Gauder, Stefan Czemmel, Christopher Mohr, Daniel J. Kowalewski, Manfred Westphal, Katrin Lamszus, Luca Regli, Michael Weller, Hans-Georg Rammensee, Helmut Salih, Marian C. Neidert, Juliane S. Walz
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1991.
https://doi.org/10.1158/1538-7445.AM2022-1991
Published: 15 June 2022
View article titled, Abstract 1991: Characterization of the exome, transcriptome, and immunopeptidome to map alterations in primary and recurrent glioblastoma
Journal Articles

Abstract LB-094: Hepavac-101 first-in-man clinical trial of a multi-peptide-based vaccine for hepatocellular carcinoma

Luigi Buonaguro, Andrea Mayer, Markus Loeffler, Sarah Missel, Roberto Accolla, Yuk Ting Ma, Tanguy Chaumette, Regina Heidenreich, Alfred Königsrainer, Joerg Ludwig, Diego Alcoba, Heiko Schuster, Cecile Gouttenfangeas, Greta Forlani, Maria Tagliamonte, Paolo A. Ascierto, Antonio Avallone, Marco Borrelli, Hans-Georg Rammensee, Bruno Sangro, Mercedes Iñarrairaegui, Sven Francque, Luisa Vonghia, Stefania Gori, Tony Weinschenk, Carsten Reinhardt, Ulrike Gnad-Vogt, Harpreet Singh
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): LB-094.
https://doi.org/10.1158/1538-7445.AM2020-LB-094
Published: 15 August 2020
View article titled, Abstract LB-094: Hepavac-101 first-in-man clinical trial of a multi-peptide-based vaccine for hepatocellular carcinoma
Journal Articles

Mapping the HLA Ligandome of Colorectal Cancer Reveals an Imprint of Malignant Cell Transformation

Markus W. Löffler, Daniel J. Kowalewski, Linus Backert, Jörg Bernhardt, Patrick Adam, Heiko Schuster, Florian Dengler, Daniel Backes, Hans-Georg Kopp, Stefan Beckert, Silvia Wagner, Ingmar Königsrainer, Oliver Kohlbacher, Lothar Kanz, Alfred Königsrainer, Hans-Georg Rammensee, Stefan Stevanović, Sebastian P. Haen
Journal: Cancer Research
Cancer Res (2018) 78 (16): 4627–4641.
https://doi.org/10.1158/0008-5472.CAN-17-1745
Published: 14 August 2018
View article titled, Mapping the HLA Ligandome of Colorectal Cancer Reveals an Imprint of Malignant Cell Transformation
Open the PDF for Mapping the HLA Ligandome of Colorectal Cancer Reveals an Imprint of Malignant Cell Transformation in another window
Includes: Supplementary data
Journal Articles

Abstract CT057: Phase I trial to evaluate the feasibility and safety of an individualized peptide vaccine of unmodified cancer antigens: PepIVAC-01

Sebastian Haen, Markus W. Löffler, Oliver Kohlbacher, Sven Nahnsen, Christopher Mohr, Monika Stieglbaueren, Patricia Hrstic, Luigi Buonaguro, Peter Martus, Maik Häntschel, Cécile Gouttefangeas, Stefan Beckert, Alfred Königsrainer, Stefan Stevanovic, Lothar Kanz, Hans-Georg Rammensee
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): CT057.
https://doi.org/10.1158/1538-7445.AM2018-CT057
Published: 01 July 2018
View article titled, Abstract CT057: Phase I trial to evaluate the feasibility and safety of an individualized peptide vaccine of unmodified cancer antigens: PepIVAC-01
Journal Articles

Abstract 2291: On- and off target toxicity profiling for adoptive cell therapy by mass spectrometry-based immunopeptidome analysis of primary human normal tissues

Oliver Schoor, Jens Fritsche, Sarah Kutscher, Andrea Mahr, Lea Stevermann, Annika Sonntag, Franziska Hoffgaard, Dominik Vahrenhorst, Julia Leibold, Valentina Goldfinger, Leonie Alten, Sebastian Bunk, Dominik Maurer, Steffen Walter, Hans-Georg Rammensee, Harpreet Singh-Jasuja, Toni Weinschenk
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2291.
https://doi.org/10.1158/1538-7445.AM2016-2291
Published: 15 July 2016
View article titled, Abstract 2291: On- and off target toxicity profiling for adoptive cell therapy by mass spectrometry-based immunopeptidome analysis of primary human normal tissues
Journal Articles

Abstract 2354: Cancer vaccine development for hepatocellular carcinoma - HEPAVAC

Sarah Kutscher, Roberto Accolla, Yuk T. Ma, Regina Heidenreich, Francesco Izzo, Alfred Koenigsrainer, Markus Loeffler, Phillip Mueller, Andrea Mayer, Hans-Georg Rammensee, Bruno Sangro, Sven Francque, Danila Valmori, Toni Weinschenk, Harpreet Singh-Jasuja, Luigi Buonaguro
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2354.
https://doi.org/10.1158/1538-7445.AM2016-2354
Published: 15 July 2016
View article titled, Abstract 2354: Cancer vaccine development for hepatocellular carcinoma - HEPAVAC
Journal Articles

Abstract 2654: GAPVAC-101 phase I trial: First data of an innovative actively personalized peptide vaccination trial in patients with newly diagnosed glioblastoma

Norbert Hilf, Katrin Frenzel, Sabrina Kuttruff-Coqui, Sandra Heesch, Sebastian Kreiter, Arie Admon, Valesca Bukur, Sjoerd van der Burg, Cecile Gouttefangeas, Judith R. Kroep, Marij Schoenmaekers-Welters, Jordi Piro, Berta Ponsati, Hans Skovgaard Poulsen, Ulrik Lassen, Francisco Martinez-Ricarte, Jordi Rodon, Juan Sahuquillo, Monika Stieglbauer, Stefan Stevanovic, Per thor Straten, Marco Skardelly, Ghazaleh Tabatabai, Michael Platten, David Capper, Andreas von Deimling, Valérie Dutoit, Hideho Okada, Christian Ottensmeier, Randi Kristina Feist, Jens Fritsche, Karoline Laske, Peter Lewandrowski, Martin Löwer, Regina Mendryzk, Miriam Meyer, Carsten Reinhardt, Bernhard Rössler, Anna Paruzynski, Nina Pawlowski, Colette Song, Stevermann Lea, Toni Weinschenk, Christoph Huber, Hans-Georg Rammensee, Pierre-Yves Dietrich, Wick Wolfgang, Ugur Sahin, Harpreet Singh-Jasuja
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2654.
https://doi.org/10.1158/1538-7445.AM2016-2654
Published: 15 July 2016
View article titled, Abstract 2654: GAPVAC-101 phase I trial: First data of an innovative actively personalized peptide vaccination trial in patients with newly diagnosed glioblastoma
Journal Articles

Abstract SY27-03: Biomarker-guided development of novel multi-peptide cancer vaccines - from discovery to phase lll trials.

Harpreet Singh-Jasuja, Steffen Walter, Toni Weinschenk, Alexandra Kirner, Andrea Mayer-Mokler, Norbert Hilf, Oliver Schoor, Pierre-Yves Dietrich, James Richtie, Roy Rampling, Frank Mayer, Arnulf Stenzl, Brian Rini, Carsten Reinhardt, Hans-Georg Rammensee
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): SY27-03.
https://doi.org/10.1158/1538-7445.AM2013-SY27-03
Published: 15 April 2013
View article titled, Abstract SY27-03: Biomarker-guided development of novel multi-peptide cancer vaccines - from discovery to phase lll trials.
Journal Articles

Abstract 5365: Prolonged survival of patients with advanced renal cancer responding to multi-peptide vaccine IMA901 after single-dose cyclophosphamide

Steffen Walter, Toni Weinschenk, Arnulf Stenzl, Romuald Zdrojowy, Anna Pluzanska, Cezary Szczylik, Michael Staehler, Wolfram Brugger, Pierre-Yves Dietrich, Norbert Hilf, Oliver Schoor, Jens Fritsche, Andrea Mahr, Regina Mendrzyk, Dominik Maurer, Verona Vass, Claudia Trautwein, Peter Lewandrowski, Christian Flohr, Heike Pohla, Janusz J. Stanczak, Vincenzo Bronte, Susanna Mandruzzato, Tilo Biedermann, Graham Pawelec, Evelyna Derhovanessian, Hisakazu Yamagishi, Tsuneharu Miki, Fumiya Hongo, Natsuki Takaha, Kosei Hirakawa, Hiroaki Tanaka, Stefan Stevanovic, Hans-Georg Rammensee, Jürgen Frisch, Andrea Mayer-Mokler, Alexandra Kirner, James Finke, Brian Rini, Carsten Reinhardt, Harpreet Singh
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5365.
https://doi.org/10.1158/1538-7445.AM2012-5365
Published: 15 April 2012
View article titled, Abstract 5365: Prolonged survival of patients with advanced renal cancer responding to multi-peptide vaccine IMA901 after single-dose cyclophosphamide
Journal Articles

Platelet-Derived MHC Class I Confers a Pseudonormal Phenotype to Cancer Cells That Subverts the Antitumor Reactivity of Natural Killer Immune Cells

Theresa Placke, Melanie Örgel, Martin Schaller, Gundram Jung, Hans-Georg Rammensee, Hans-Georg Kopp, Helmut Rainer Salih
Journal: Cancer Research
Cancer Res (2012) 72 (2): 440–448.
https://doi.org/10.1158/0008-5472.CAN-11-1872
Published: 16 January 2012
View article titled, Platelet-Derived MHC Class I Confers a Pseudonormal Phenotype to Cancer Cells That Subverts the Antitumor Reactivity of Natural Killer Immune Cells
Open the PDF for Platelet-Derived MHC Class I Confers a Pseudonormal Phenotype to Cancer Cells That Subverts the Antitumor Reactivity of Natural Killer Immune Cells in another window
Includes: Multimedia, Supplementary data
Journal Articles

Abstract 2396: IMA950: A novel multi-peptide cancer vaccine for treatment of glioblastoma

Oliver Schoor, Norbert Hilf, Valérie Dutoit, Toni Weinschenk, Steffen Walter, Peter Lewandrowski, Sylvia Flohr, Claudia Trautwein, Cécile Gouttefangeas, Stefan Stevanović, Hans-Georg Rammensee, Philipp Beckhove, Christel Herold-Mende, Pierre-Yves Dietrich, Harpreet Singh
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2396.
https://doi.org/10.1158/1538-7445.AM10-2396
Published: 15 April 2010
View article titled, Abstract 2396: IMA950: A novel multi-peptide cancer vaccine for treatment of glioblastoma
Journal Articles

Simultaneous Infiltration of Polyfunctional Effector and Suppressor T Cells into Renal Cell Carcinomas

Sebastian Attig, Jörg Hennenlotter, Graham Pawelec, Gerd Klein, Sven D. Koch, Hanspeter Pircher, Susan Feyerabend, Dorothee Wernet, Arnulf Stenzl, Hans-Georg Rammensee, Cécile Gouttefangeas
Journal: Cancer Research
Cancer Res (2009) 69 (21): 8412–8419.
https://doi.org/10.1158/0008-5472.CAN-09-0852
Published: 28 October 2009
View article titled, Simultaneous Infiltration of Polyfunctional Effector and Suppressor T Cells into Renal Cell Carcinomas
Open the PDF for Simultaneous Infiltration of Polyfunctional Effector and Suppressor T Cells into Renal Cell Carcinomas in another window
Includes: Supplementary data
Journal Articles

Tumor-Associated MICA Is Shed by ADAM Proteases

Inja Waldhauer, Dennis Goehlsdorf, Friederike Gieseke, Toni Weinschenk, Mareike Wittenbrink, Andreas Ludwig, Stefan Stevanovic, Hans-Georg Rammensee, Alexander Steinle
Journal: Cancer Research
Cancer Res (2008) 68 (15): 6368–6376.
https://doi.org/10.1158/0008-5472.CAN-07-6768
Published: 01 August 2008
View article titled, Tumor-Associated MICA Is Shed by ADAM Proteases
Open the PDF for Tumor-Associated MICA Is Shed by ADAM Proteases in another window
Includes: Supplementary data
Journal Articles

A Cryptic Vascular Endothelial Growth Factor T-Cell Epitope: Identification and Characterization by Mass Spectrometry and T-Cell Assays

Andreas O. Weinzierl, Dominik Maurer, Florian Altenberend, Nicole Schneiderhan-Marra, Karin Klingel, Oliver Schoor, Dorothee Wernet, Thomas Joos, Hans-Georg Rammensee, Stefan Stevanović
Journal: Cancer Research
Cancer Res (2008) 68 (7): 2447–2454.
https://doi.org/10.1158/0008-5472.CAN-07-2540
Published: 01 April 2008
View article titled, A Cryptic Vascular Endothelial Growth Factor T-Cell Epitope: Identification and Characterization by Mass Spectrometry and T-Cell Assays
Open the PDF for A Cryptic Vascular Endothelial Growth Factor T-Cell Epitope: Identification and Characterization by Mass Spectrometry and T-Cell Assays in another window
Includes: Supplementary data