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Journal Articles

Abstract IA016: RNA-based precision medicine predicts sensitivity to selinexor in select pancreatic ductal adenocarcinoma patients

Alvaro Curiel Garcia, Lorenzo Tomassoni, Tanner C. Dalton, Amanda R. Decker-Farrell, Carmine F. Palermo, Daniel R. Ross, Stephen A. Sastra, Urszula N. Wasko, Isabel M. Goncalves, Prabhot Mundi, Basil S. Bakir, Rachael A. Safyan, Hanina Hibshoosh, Gulam A. Manji, Andrea Califano
Journal: Cancer Research
Cancer Res (2025) 85 (5_Supplement): IA016.
https://doi.org/10.1158/1538-7445.GENFUNC25-IA016
Published: 11 March 2025
View article titled, Abstract IA016: RNA-based precision medicine predicts sensitivity to selinexor in select pancreatic ductal adenocarcinoma patients
Journal Articles

Abstract A074: Integrated clinical and single-cell profiling analysis reveals cellular states associated with metastatic organotropism and survival in patients with pancreatic ductal adenocarcinoma

Morteza Chalabi Hajkarim, Michael May, Amit Dipak Amin, Jacob Jamison, Somnath Tagore, Lindsay Caprio, Zachary Walsh, Parin Shah, Sinan Abuzaid, Alissa Michel, Sun Dajiang, Winston Wong, Neha Shaikh, Priyanka Ramaradj, Basil Bakir, Michael D Kluger, John Chabot, Hanina Hibshoosh, Anil K Rustgi, Alexander Raufi, Gulam A Manji, Benjamin Izar
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement_2): A074.
https://doi.org/10.1158/1538-7445.PANCREATIC24-A074
Published: 15 September 2024
View article titled, Abstract A074: Integrated clinical and single-cell profiling analysis reveals cellular states associated with metastatic organotropism and survival in patients with pancreatic ductal adenocarcinoma
Journal Articles

Abstract 934: RNA-based precision medicine predicts sensitivity to selinexor in select pancreatic ductal adenocarcinoma patients

Alvaro Curiel-Garcia, Lorenzo Tomassoni, Tanner C. Dalton, Amanda R. Decker-Farrell, Carmine F. Palermo, Daniel R. Ross, Stephen A. Sastra, Urszula N. Wasko, Isabel M. Goncalves, Prabhot Mundi, Basil S. Bakir, Rachael A. Safyan, Hanina Hibshoosh, Gulam A. Manji, Andrea Califano, Kenneth P. Olive
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 934.
https://doi.org/10.1158/1538-7445.AM2024-934
Published: 22 March 2024
View article titled, Abstract 934: RNA-based precision medicine predicts sensitivity to selinexor in select pancreatic ductal adenocarcinoma patients
Journal Articles

Abstract 994: Single analyte profiling of the mutational, immune and microbiome landscape in african american colon cancer patients

Carino Gurjao, Edmond Chan, Michael J. Lee, Sho Hangai, Raul Rabadan, Tal Korem, Hanina Hibshoosh, Benjamin Izar
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 994.
https://doi.org/10.1158/1538-7445.AM2024-994
Published: 22 March 2024
View article titled, Abstract 994: Single analyte profiling of the mutational, immune and microbiome landscape in african american colon cancer patients
Journal Articles

Abstract 5360: Relief of chromosomal instability-induced cGAS-STING signaling sensitizes STK11-mutant non-small cell lung cancer to immune checkpoint blockade

Lindsay A. Caprio, Christy Hong, Amit D. Amin, Somnath Tagore, Mercedes Duran, Meri Rogava, Luke Cai, Leon Ebel, Johannes Melms, Hanina Hibshoosh, Samuel Bakhoum, Benjamin Izar
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5360.
https://doi.org/10.1158/1538-7445.AM2024-5360
Published: 22 March 2024
View article titled, Abstract 5360: Relief of chromosomal instability-induced cGAS-STING signaling sensitizes <em>STK11</em>-mutant non-small cell lung cancer to immune checkpoint blockade
Journal Articles

Abstract 5944: Relief of chromosomal instability-induced cGAS-STING signaling sensitizes STK11-mutant non-small cell lung cancer to immune checkpoint blockade

Lindsay A. Caprio, Christy Hong, Amit Dipak Amin, Somnath Tagore, Johannes Melms, Luke Cai, Yiping Wang, Patricia Ho, Michael Mu, Hanina Hibshoosh, Brian Henick, Kwok K. Wong, Samuel F. Bakhoum, Benjamin Izar
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5944.
https://doi.org/10.1158/1538-7445.AM2023-5944
Published: 04 April 2023
View article titled, Abstract 5944: Relief of chromosomal instability-induced cGAS-STING signaling sensitizes <em>STK11</em>-mutant non-small cell lung cancer to immune checkpoint blockade
Journal Articles

Abstract 3517: Multi-modal single-cell and spatial genomics reveals genomic, adaptive and microenvironmental features of human non-small cell lung cancer brain metastasis

Somnath Tagore, Lindsay Caprio, Amit Dipak Amin, Irving Barrera, Johannes Melms, Karan Luthria, Yiping Wang, Yohanna Georgis, Abhi Jaiswal, Galina G. Lagos, Zachary Walsh, Parin Shah, Jana Biermann, Neha Sheikh, Priyanka Ramaradj, Niroshana Anandasabapathy, Hanina Hibshoosh, Gary Schwartz, Brian Henick, Alison Taylor, Fei Chen, Benjamin Izar
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3517.
https://doi.org/10.1158/1538-7445.AM2023-3517
Published: 04 April 2023
View article titled, Abstract 3517: Multi-modal single-cell and spatial genomics reveals genomic, adaptive and microenvironmental features of human non-small cell lung cancer brain metastasis
Journal Articles

Abstract P3-07-22: Presurgical Trial of Metformin plus Atorvastatin in Women with Operable Breast Cancer

Julia E. McGuinness, Katherine D. Crew, Meghna S. Trivedi, Melissa K. Accordino, Shing M. Lee, Hua Guo, Hanina Hibshoosh, Dawn Hershman, Kevin Kalinsky
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P3-07-22.
https://doi.org/10.1158/1538-7445.SABCS22-P3-07-22
Published: 01 March 2023
View article titled, Abstract P3-07-22: Presurgical Trial of Metformin plus Atorvastatin in Women with Operable Breast Cancer
Journal Articles

Abstract 984: Dissecting the ecosystem of treatment-naïve melanoma brain metastasis using multi-modal single-cell analysis

Johannes C. Melms, Jana Biermann, Amit Dipak Amin, Yiping Wang, Somnath Tagore, Massimo Andreatta, Ajay Nair, Meri Rogava, Patricia Ho, Lindsay A. Caprio, Zachary H. Walsh, Shivem Shah, Daniel H. Vacarro, Blake Caldwell, Adrienne M. Luoma, Joseph Driver, Matthew Ingham, Suthee Rapisuwon, Jennifer Wargo, Craig L. Slinguff, Evan Z. Macosco, Fei Chen, Richard Carvajal, Michael B. Atkins, Michael A. Davies, Elham Azizi, Santiago J. Carmona, Hanina Hibshoosh, Peter D. Canoll, Jeffrey N. Bruce, Wenya L. Bi, Gary K. Schwartz, Benjamin Izar
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 984.
https://doi.org/10.1158/1538-7445.AM2022-984
Published: 15 June 2022
View article titled, Abstract 984: Dissecting the ecosystem of treatment-naïve melanoma brain metastasis using multi-modal single-cell analysis
Journal Articles

Abstract P3-05-04: The histone demethylase hairless functions as a tumor suppressor gene in breast cancer development

Liang Liu, Yao Shen, Jasvinder Singh, Bindy Sah, Zhongming Chen, Christine Henzler, Wootae Ha, Tao Su, Hanina Hibshoosh
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-05-04.
https://doi.org/10.1158/1538-7445.SABCS21-P3-05-04
Published: 15 February 2022
View article titled, Abstract P3-05-04: The histone demethylase hairless functions as a tumor suppressor gene in breast cancer development
Journal Articles

Abstract P2-07-09: Characterization of the tumor microenvironment in patients with hormone receptor positive, HER2 negative early breast cancer

Matthew Ryan Kearney, Rami Vanguri, Qi Wang, Kathleen Fenn, Hua Guo, Douglas Marks, Hanina Hibshoosh, Kevin M Kalinsky, Eileen Connolly
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P2-07-09.
https://doi.org/10.1158/1538-7445.SABCS21-P2-07-09
Published: 15 February 2022
View article titled, Abstract P2-07-09: Characterization of the tumor microenvironment in patients with hormone receptor positive, HER2 negative early breast cancer
Journal Articles

Abstract P3-02-04: Prediction of breast cancer response to neoadjuvant chemotherapy in different biological breast cancer subtypes using diffuse optical tomography

Mirella L Altoe, Kevin M Kalinsky, Hua Guo, Hanina Hibshoosh, Mariella Tejada, Katherine D Crew, Melissa K Accordino, Meghna S Trivedi, Alessandro Marone, Hyun K Kim, Andreas H Hielscher, Dawn L Hershman
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-02-04.
https://doi.org/10.1158/1538-7445.SABCS21-P3-02-04
Published: 15 February 2022
View article titled, Abstract P3-02-04: Prediction of breast cancer response to neoadjuvant chemotherapy in different biological breast cancer subtypes using diffuse optical tomography
Journal Articles

Abstract PS3-10: Monitoring neoadjuvant chemotherapy using diffuse optical tomography breast imaging system

Mirella L Altoe, Kevin Kalinsky, Hua Guo, Hanina Hibshoosh, Mariella Tejada, Katherine D Crew, Melissa K Accordino, Meghna Trivedi, Alessandro Marone, Hyun K Kim, Andreas H Hielscher, Dawn L Hershman
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS3-10.
https://doi.org/10.1158/1538-7445.SABCS20-PS3-10
Published: 15 February 2021
View article titled, Abstract PS3-10: Monitoring neoadjuvant chemotherapy using diffuse optical tomography breast imaging system
Journal Articles

Abstract LB-003: OncoMatch: Unbiased, quantitative assessment of cancer model fidelity for drug sensitivity and mechanism of action elucidation

Mariano J. Alvarez, Yan Pengrong, Mary L. Alpaugh, Michaela Bowden, Ewa T. Sicinska, Chensheng W. Zhou, Charles Karan, Ronald B. Realubit, Prabhjot S. Mundi, Adina Grunn, Jager Dirk, John A. Chabot, Antonio T. Fojo, Paul E. Oberstein, Hanina Hibshoosh, Jeffrey W. Milsom, Matthew H. Kulke, Massimo Loda, Gabriela Chiosis, Diane L. Reidy-Lagunes, Andrea Califano
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): LB-003.
https://doi.org/10.1158/1538-7445.AM2020-LB-003
Published: 15 August 2020
View article titled, Abstract LB-003: OncoMatch: Unbiased, quantitative assessment of cancer model fidelity for drug sensitivity and mechanism of action elucidation
Journal Articles

Abstract P6-10-25: Characterization of the tumor immune microenvironment (TME) in early stage HR-positive HER2-positive breast cancer

Kathleen M. Fenn, Douglas K Marks, Rami Vanguri, Shuobo Boboila, Hua Guo, Hanina Hibshoosh, Kevin Kalinsky, Eileen Connolly
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P6-10-25.
https://doi.org/10.1158/1538-7445.SABCS19-P6-10-25
Published: 15 February 2020
View article titled, Abstract P6-10-25: Characterization of the tumor immune microenvironment (TME) in early stage HR-positive HER2-positive breast cancer
Journal Articles

Abstract P1-01-02: Early changes in diffuse optical tomography predicts pathologic complete response to neoadjuvant chemotherapy in triple-negative breast cancer

Mirella L Altoe, Kevin Kalinsky, Hua Guo, Hanina Hibshoosh, Mariella Tejada, Katherine D Crew, Melissa K Accordino, Meghna S Trivedi, Alessandro Marone, Hyun K Kim, Andreas H Hielscher, Dawn L Hershman
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P1-01-02.
https://doi.org/10.1158/1538-7445.SABCS19-P1-01-02
Published: 15 February 2020
View article titled, Abstract P1-01-02: Early changes in diffuse optical tomography predicts pathologic complete response to neoadjuvant chemotherapy in triple-negative breast cancer
Journal Articles

Abstract P3-09-17: Preoperative pembrolizumab increases sTILs in treatment naïve stage I/IIA TNBC patients in a window of opportunity trial

Rami Vanguri, Hua Guo, Shuobo Boboila, Tahsin Kurc, Han Le, Shahira Abousamra, Le Hou, Dimitris Samaras, Rajarsi Gupta, Joel Saltz, Kevin Gardner, Hanina Hibshoosh, Kevin Kalinsky, Eileen Connolly
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P3-09-17.
https://doi.org/10.1158/1538-7445.SABCS19-P3-09-17
Published: 15 February 2020
View article titled, Abstract P3-09-17: Preoperative pembrolizumab increases sTILs in treatment naïve stage I/IIA TNBC patients in a window of opportunity trial
Journal Articles

Abstract LB-224: Tyrosine phosphorylation of p27Kip1 associates with Palbociclib responsiveness in breast cancer

Stacy W. Blain, Susan R.S. Gottesman, Jonathan Somma, Vladislav Tsiperson, Julia McGuinness, Matthew Ingham, Kevin Kalinsky, Gary Schwartz, Elina Tress, Hanina Hibshoosh, Mohamed Mh Kahila, Bachar Samra Samra, Evelyn Taiwo, Steve Xie
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-224.
https://doi.org/10.1158/1538-7445.AM2019-LB-224
Published: 01 July 2019
View article titled, Abstract LB-224: Tyrosine phosphorylation of p27Kip1 associates with Palbociclib responsiveness in breast cancer
Journal Articles

Abstract 2555: Promoter DNA methylation patterns in breast tumor and matched adjacent non-tumor tissues in the breast cancer family registry

Hui-Chen Wu, Hanina Hibshoosh, Regina Santella, Mary Beth Terry
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2555.
https://doi.org/10.1158/1538-7445.AM2016-2555
Published: 15 July 2016
View article titled, Abstract 2555: Promoter DNA methylation patterns in breast tumor and matched adjacent non-tumor tissues in the breast cancer family registry
Journal Articles

Abstract OT1-1-08: Master regulator (MR)-directed therapy in residual breast cancer patient derived xenografts (PDXs)

Kevin Kalinsky, Prabhjot Mundi, Dawn L Hershman, Eileen Connolly, Katherine D Crew, Hanina Hibshoosh, Andrea Calfiano, Matthew Maurer
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): OT1-1-08.
https://doi.org/10.1158/1538-7445.SABCS14-OT1-1-08
Published: 01 May 2015
View article titled, Abstract OT1-1-08: Master regulator (MR)-directed therapy in residual breast cancer patient derived xenografts (PDXs)