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Journal Articles

Abstract 6657: Oncolytic Vaccinia Virus Carrying OPCML Tumor Suppressor is active in Epithelial Ovarian Cancer

Yong Tang, Yingzhao Liu, Mingjing Deng, Fei Huang, Jiahu Wang, Paul Blake, Hani Gabra, Qi Wang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6657.
https://doi.org/10.1158/1538-7445.AM2024-6657
Published: 22 March 2024
View article titled, Abstract 6657: Oncolytic Vaccinia Virus Carrying OPCML Tumor Suppressor is active in Epithelial Ovarian Cancer
Journal Articles

Abstract 2087: AXL inhibition enhances Type 1 interferon (IFN) response and potentiates chemo-immunotherapy

Sushil Dhakal, Sébastien Bougnaud, James B. Lorens, Gro Gausdal, Emmanuel E. Moutoussamy, Hani Gabra
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2087.
https://doi.org/10.1158/1538-7445.AM2022-2087
Published: 15 June 2022
View article titled, Abstract 2087: AXL inhibition enhances Type 1 interferon (IFN) response and potentiates chemo-immunotherapy
Journal Articles

Abstract 4909: Adaptive oncology phase 1 study of first-in-class inhibitor of ataxia telangiectasia mutated protein kinase (ATM), in combination with olaparib

Yingxue Chen, Martin Pass, Nuria Bui Bruna, Christine Stephens, Andrew Pierce, Wouter Hanekom, Hani Gabra, Helen Tomkinson, Nidal Al-Huniti
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4909.
https://doi.org/10.1158/1538-7445.AM2018-4909
Published: 01 July 2018
View article titled, Abstract 4909: Adaptive oncology phase 1 study of first-in-class inhibitor of ataxia telangiectasia mutated protein kinase (ATM), in combination with olaparib
Journal Articles

Abstract A2-13: Targeting genomic instability to identify molecular drivers of poor prognosis in cancer.

Karen A. Menezes, Paula Cunnea, Phillip Lawton, Ed Curry, Hani Gabra, Harpreet Wasan, Surinder K. Sharma, Euan A. Stronach
Journal: Cancer Research
Cancer Res (2015) 75 (22_Supplement_1): A2-13.
https://doi.org/10.1158/1538-7445.TRANSCAGEN-A2-13
Published: 15 November 2015
View article titled, Abstract A2-13: Targeting genomic instability to identify molecular drivers of poor prognosis in cancer.
Journal Articles

Abstract CT204: Preliminary results from PiSARRO, a phase Ib/II study of APR-246, a mutant p53 reactivating small molecule, in combination with standard chemotherapy in platinum-sensitive ovarian cancer

Mikael von Euler, Klas G. Wiman, Hani Gabra, James D. Brenton, Bristi Basu, Ignace Vergote, Charlie Gourley, Austin Smith, Jessica Alfredsson, Nina Mohell, John A. Green
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): CT204.
https://doi.org/10.1158/1538-7445.AM2015-CT204
Published: 01 August 2015
View article titled, Abstract CT204: Preliminary results from PiSARRO, a phase Ib/II study of APR-246, a mutant p53 reactivating small molecule, in combination with standard chemotherapy in platinum-sensitive ovarian cancer
Journal Articles

Abstract LB-149: The OPCML tumor suppressor binds and negatively regulates the Axl receptor tyrosine kinase, sensitizing cells to foretinib in epithelial ovarian cancer (EOC)

Sushmita Roy Nawathe, Elisa Zanini, Giles Hayward, Arthur B. McKie, Hani Gabra
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-149.
https://doi.org/10.1158/1538-7445.AM2012-LB-149
Published: 15 April 2012
View article titled, Abstract LB-149: The OPCML tumor suppressor binds and negatively regulates the Axl receptor tyrosine kinase, sensitizing cells to foretinib in epithelial ovarian cancer (EOC)
Journal Articles

Abstract 5107: Unravelling the complexity of individual cancer genomes

Francesca Menghi, XingYi Woo, Min Gong, Sigrid L. Rouam, Denis Bertrand, Wah H. Lee, Wendy Wang, Nona Rama, Euan A. Stronach, Krishna Karuturi, Hani Gabra, Roshan Agarwal, Edison T. Liu
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5107.
https://doi.org/10.1158/1538-7445.AM2012-5107
Published: 15 April 2012
View article titled, Abstract 5107: Unravelling the complexity of individual cancer genomes
Journal Articles

HDAC4-Regulated STAT1 Activation Mediates Platinum Resistance in Ovarian Cancer

Euan A. Stronach, Albandri Alfraidi, Nona Rama, Christoph Datler, James B. Studd, Roshan Agarwal, Tankut G. Guney, Charlie Gourley, Bryan T. Hennessy, Gordon B. Mills, Antonello Mai, Robert Brown, Roberto Dina, Hani Gabra
Journal: Cancer Research
Cancer Res (2011) 71 (13): 4412–4422.
https://doi.org/10.1158/0008-5472.CAN-10-4111
Published: 30 June 2011
View article titled, HDAC4-Regulated STAT1 Activation Mediates Platinum Resistance in Ovarian Cancer
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Includes: Supplementary data
Journal Articles

Abstract 1616: The OPCML tumor suppressor negatively regulates a specific repertoire of 5 receptor tyrosine kinases via a novel proteasomal mechanism, and its recombinant derivative is a potent in-vivo anticancer protein therapy

Arthur B. McKie, Sebastian Vaughan, Imoh Okon, Joshua L.C. Wong, Elisa Zanini, Eric W-F Lam, Naomi E. Chayen, Hani Gabra
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1616.
https://doi.org/10.1158/1538-7445.AM2011-1616
Published: 15 April 2011
View article titled, Abstract 1616: The OPCML tumor suppressor negatively regulates a specific repertoire of 5 receptor tyrosine kinases via a novel proteasomal mechanism, and its recombinant derivative is a potent in-vivo anticancer protein therapy
Journal Articles

WWOX Gene Expression Abolishes Ovarian Cancer Tumorigenicity In vivo and Decreases Attachment to Fibronectin via Integrin α3

Charlie Gourley, Adam J.W. Paige, Karen J. Taylor, Carol Ward, Barbara Kuske, Jieqing Zhang, Mingjun Sun, Szymon Janczar, David J. Harrison, Morwenna Muir, John F. Smyth, Hani Gabra
Journal: Cancer Research
Cancer Res (2009) 69 (11): 4835–4842.
https://doi.org/10.1158/0008-5472.CAN-08-2974
Published: 01 June 2009
View article titled, <em>WWOX</em> Gene Expression Abolishes Ovarian Cancer Tumorigenicity <em>In vivo</em> and Decreases Attachment to Fibronectin via Integrin α<sub>3</sub>
Open the PDF for <em>WWOX</em> Gene Expression Abolishes Ovarian Cancer Tumorigenicity <em>In vivo</em> and Decreases Attachment to Fibronectin via Integrin α<sub>3</sub> in another window
Includes: Supplementary data
Journal Articles

Abstract #LB-108: The OPCML tumor suppressor negatively regulates expression and activity of HER2 and EGFR, and may predict ovarian and breast cancer response to Lapatinib

Arthur McKie, Imoh Okon, Sebastian Vaughan, Dmitry Shaposhnikov, Joshua Wong, Justin Stebbing, Roshan Agarwal, Roberto Dina, Mona El-Bahrawy, Eric Lam, Hani Gabra
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): LB-108.
Published: 01 May 2009
View article titled, Abstract #LB-108: The OPCML tumor suppressor negatively regulates expression and activity of HER2 and EGFR, and may predict ovarian and breast cancer response to Lapatinib
Journal Articles

Identification of functional modulators of platinum resistance using isogenically matched ovarian cancer cell line models.

Euan Stronach, Nona Rama, Hani Gabra
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 699.
Published: 01 May 2008
View article titled, Identification of functional modulators of platinum resistance using isogenically matched ovarian cancer cell line models.
Journal Articles

10th Biennial Helene Harris Memorial Trust Meeting

Frances R. Balkwill, Alan Ashworth, Robert C. Bast, Jonathon S. Berek, Jeff Boyd, Mary L. Disis, Hani Gabra, Martin E. Gore, Thomas C. Hamilton, Ian J. Jacobs, Stan B. Kaye, Elise C. Kohn, Gordon B. Mills, Nicole D. Urban
Journal: Cancer Research
Cancer Res (2006) 66 (6): 2904–2906.
https://doi.org/10.1158/0008-5472.CAN-05-2093
Published: 15 March 2006
View article titled, 10th Biennial Helene Harris Memorial Trust Meeting
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Journal Articles

CpG Island Methylation of DNA Damage Response Genes in Advanced Ovarian Cancer

Jens M. Teodoridis, Jacqueline Hall, Sharon Marsh, Hilary D. Kannall, Catriona Smyth, Jorge Curto, Nadeem Siddiqui, Hani Gabra, Howard L. McLeod, Gordon Strathdee, Robert Brown
Journal: Cancer Research
Cancer Res (2005) 65 (19): 8961–8967.
https://doi.org/10.1158/0008-5472.CAN-05-1187
Published: 03 October 2005
View article titled, CpG Island Methylation of DNA Damage Response Genes in Advanced Ovarian Cancer
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Journal Articles

Microarray analysis of OPCML tumor suppressor function in SKOV-3 ovarian cancer cells

Genevieve J. Rabiasz, Diane Scott, Eric P. Miller, Euan A. Stronach, Karen J. Taylor, Evangelos Ntougkos, Hani Gabra, John F. Smyth, Grant C. Sellar
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 639–640.
Published: 01 May 2005
View article titled, Microarray analysis of OPCML tumor suppressor function in SKOV-3 ovarian cancer cells
Journal Articles

The IgLON family in epithelial ovarian cancer: an expression study

Evangelos Ntougkos, Robert Rush, Diane Scott, Hani Gabra, John F. Smyth, Grant C. Sellar
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 639.
Published: 01 May 2005
View article titled, The IgLON family in epithelial ovarian cancer: an expression study
Journal Articles

Reconstituted WWOX expression in PEO1 ovarian cancer cells results in abolition of tumorigenicity in nude mice and decreased migration towards matrix components

Charlie Gourley, Adam J. Paige, Karen J. Taylor, Diane Scott, Hani Gabra, John F. Smyth
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 412–413.
Published: 01 April 2004
View article titled, Reconstituted <em>WWOX</em> expression in PEO1 ovarian cancer cells results in abolition of tumorigenicity in nude mice and decreased migration towards matrix components
Journal Articles

Identification of Clinically Relevant Genes on Chromosome 11 in a Functional Model of Ovarian Cancer Tumor Suppression

Euan A. Stronach, Grant C. Sellar, Cherie Blenkiron, Genevieve J. Rabiasz, Karen J. Taylor, Eric P. Miller, Charles E. Massie, Awatif Al-Nafussi, John F. Smyth, David J. Porteous, Hani Gabra
Journal: Cancer Research
Cancer Res (2003) 63 (24): 8648–8655.
Published: 24 December 2003
View article titled, Identification of Clinically Relevant Genes on Chromosome 11 in a Functional Model of Ovarian Cancer Tumor Suppression
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Journal Articles

BARX2 Induces Cadherin 6 Expression and Is a Functional Suppressor of Ovarian Cancer Progression

Grant C. Sellar, Li Li, Karen P. Watt, Barry D. Nelkin, Genevieve J. Rabiasz, Euan A. Stronach, Eric P. Miller, David J. Porteous, John F. Smyth, Hani Gabra
Journal: Cancer Research
Cancer Res (2001) 61 (19): 6977–6981.
Published: 01 October 2001
View article titled, BARX2 Induces Cadherin 6 Expression and Is a Functional Suppressor of Ovarian Cancer Progression
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Journal Articles

A 700-kb Physical Map of a Region of 16q23.2 Homozygously Deleted in Multiple Cancers and Spanning the Common Fragile Site FRA16D

Adam J. W. Paige, Karen J. Taylor, Aengus Stewart, John G. Sgouros, Hani Gabra, Grant C. Sellar, John F. Smyth, David J. Porteous, J. E. Vivienne Watson
Journal: Cancer Research
Cancer Res (2000) 60 (6): 1690–1697.
Published: 01 March 2000
View article titled, A 700-kb Physical Map of a Region of 16q23.2 Homozygously Deleted in Multiple Cancers and Spanning the Common Fragile Site FRA16D
Open the PDF for A 700-kb Physical Map of a Region of 16q23.2 Homozygously Deleted in Multiple Cancers and Spanning the Common Fragile Site FRA16D in another window