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Abstract 4768: Development of fully human TCR-mimic antibodies targeting intracellular tumor antigens using humanized RenTCR-mimic transgenic mice

Han Zhang, Wanbo Tang, Jun Du, Yue Zhang, Limin Zhao, Xin Jiao, Baihong Liu, Yi Yang

Cancer Res (2025) 85 (8_Supplement_1): 4768.

https://doi.org/10.1158/1538-7445.AM2025-4768

Published: 21 April 2025

View articletitled, Abstract 4768: Development of fully human TCR-mimic antibodies targeting intracellular tumor antigens using humanized RenTCR-mimic transgenic mice

Journal Articles

Abstract 3861: Associations of intragenic rearrangement burden with immune cell infiltration and response to immune checkpoint blockade in cancer

Han Zhang, Sanghoon Lee, Renee R. Muthakana, Binfeng Lu, David N Boone, Daniel Lee, Xiaosong Wang

Cancer Res (2024) 84 (6_Supplement): 3861.

https://doi.org/10.1158/1538-7445.AM2024-3861

Published: 22 March 2024

View articletitled, Abstract 3861: Associations of intragenic rearrangement burden with immune cell infiltration and response to immune checkpoint blockade in cancer

Journal Articles

Abstract 2127: TERT C228T and KDM6A alterations are potential predictive biomarkers in non-muscle-invasive bladder cancer treated with intravesical Bacillus Calmette-Guérin instillation

Cancer Res (2023) 83 (7_Supplement): 2127.

https://doi.org/10.1158/1538-7445.AM2023-2127

Published: 04 April 2023

View articletitled, Abstract 2127: TERT C228T and KDM6A alterations are potential predictive biomarkers in non-muscle-invasive bladder cancer treated with intravesical Bacillus Calmette-Guérin instillation

Journal Articles

Abstract 1469: TPX-0131, a potent inhibitor of wild type ALK and a broad spectrum of both single and compound ALK resistance mutations

Brion W. Murray, Dayong Zhai, Wei Deng, Evan Rogers, Xin Zhang, Jane Ung, Vivian Nguyen, Han Zhang, Maria Barrera, Ana Parra, Jessica Cowell, Dong Lee, Herve Aloysius

Cancer Res (2021) 81 (13_Supplement): 1469.

https://doi.org/10.1158/1538-7445.AM2021-1469

Published: 01 July 2021

View articletitled, Abstract 1469: TPX-0131, a potent inhibitor of wild type ALK and a broad spectrum of both single and compound ALK resistance mutations

Journal Articles

Genome-Wide Association Study Data Reveal Genetic Susceptibility to Chronic Inflammatory Intestinal Diseases and Pancreatic Ductal Adenocarcinoma Risk

Fangcheng Yuan, Rayjean J. Hung, Naomi Walsh, Han Zhang, Elizabeth A. Platz, William Wheeler, Lei Song, Alan A. Arslan, Laura E. Beane Freeman, Paige Bracci, Federico Canzian, Mengmeng Du, Steven Gallinger, Graham G. Giles, Phyllis J. Goodman, Charles Kooperberg, Loic Le Marchand, Rachel E. Neale, Jonas Rosendahl, Ghislaine Scelo, Xiao-Ou Shu, Kala Visvanathan, Emily White, Wei Zheng, Demetrius Albanes, Pilar Amiano, Gabriella Andreotti, Ana Babic, William R. Bamlet, Sonja I. Berndt, Paul Brennan, Bas Bueno-de-Mesquita, Julie E. Buring, Peter T. Campbell, Stephen J. Chanock, Charles S. Fuchs, J. Michael Gaziano, Michael G. Goggins, Thilo Hackert, Patricia Hartge, Manal M. Hassan, Elizabeth A. Holly, Robert N. Hoover, Verena Katzke, Holger Kirsten, Robert C. Kurtz, I-Min Lee, Nuria Malats, Roger L. Milne, Neil Murphy, Kimmie Ng, Ann L. Oberg, Miquel Porta, Kari G. Rabe, Francisco X. Real, Nathaniel Rothman, Howard D. Sesso, Debra T. Silverman, Ian M. Thompson, Jean Wactawski-Wende, Xiaoliang Wang, Nicolas Wentzensen, Lynne R. Wilkens, Herbert Yu, Anne Zeleniuch-Jacquotte, Jianxin Shi, Eric J. Duell, Laufey T. Amundadottir, Donghui Li, Gloria M. Petersen, Brian M. Wolpin, Harvey A. Risch, Kai Yu, Alison P. Klein, Rachael Stolzenberg-Solomon

Cancer Res (2020) 80 (18): 4004–4013.

https://doi.org/10.1158/0008-5472.CAN-20-0447

Published: 15 September 2020

View articletitled, Genome-Wide Association Study Data Reveal Genetic Susceptibility to Chronic Inflammatory Intestinal Diseases and Pancreatic Ductal Adenocarcinoma Risk

Includes: Supplementary data

Journal Articles

Abstract CT127: A phase I study of cMET inhibitor bozitinib in patients with advanced NSCLC harboring cMET alterations

Jinji Yang, Qing Zhou, Huajun Chen, Lin Wu, Jun Zhao, Renhua Guo, Yun Fan, Hepeng Shi, Weizhe Xue, Peilong Zhang, Han-Zhang Han, Xuan Lin, Shuyin Chen, Lu Zhang, Hao Liu, Xinru Mao, Bin Gan, Yilong Wu

Cancer Res (2020) 80 (16_Supplement): CT127.

https://doi.org/10.1158/1538-7445.AM2020-CT127

Published: 15 August 2020

View articletitled, Abstract CT127: A phase I study of cMET inhibitor bozitinib in patients with advanced NSCLC harboring cMET alterations

Journal Articles

Abstract 5226: TPX-0131: A next generation macrocyclic ALK inhibitor that overcomes ALK resistant mutations refractory to current approved ALK inhibitors

J. Jean Cui, Evan Rogers, Dayong Zhai, Wei Deng, Jane Ung, Vivian Nguyen, Han Zhang, Xin Zhang, Ana Parra, Maria Barrera, Dong Lee, Brion Murray

Cancer Res (2020) 80 (16_Supplement): 5226.

https://doi.org/10.1158/1538-7445.AM2020-5226

Published: 15 August 2020

View articletitled, Abstract 5226: TPX-0131: A next generation macrocyclic ALK inhibitor that overcomes ALK resistant mutations refractory to current approved ALK inhibitors

Journal Articles

Abstract 4899: Investigating mutation co-operativity in early tumorigenesis of low-grade serous ovarian carcinoma with organoid model system and single-cell RNA sequencing

Joyce Yu Han Zhang, Dawn Cochrane, Kieran Campbell, Minh Bui, Germain Ho, Cindy Shen, Winnie Yang, Clara Salamanca, Genny Trigo, David G. Huntsman

Cancer Res (2020) 80 (16_Supplement): 4899.

https://doi.org/10.1158/1538-7445.AM2020-4899

Published: 15 August 2020

View articletitled, Abstract 4899: Investigating mutation co-operativity in early tumorigenesis of low-grade serous ovarian carcinoma with organoid model system and single-cell RNA sequencing

Journal Articles

Abstract 2302: Methylation profiling of circulating tumor DNA for the detection of ovarian cancer

Ning Li, Yu Zhang, Xin Zhu, Zhenjing Zhang, Jiayue Xu, Bingsi Li, Han Han-Zhang, Fujun Qiu, Shuai Fang, Hao Liu, Zhihong Zhang

Cancer Res (2020) 80 (16_Supplement): 2302.

https://doi.org/10.1158/1538-7445.AM2020-2302

Published: 15 August 2020

View articletitled, Abstract 2302: Methylation profiling of circulating tumor DNA for the detection of ovarian cancer

Journal Articles

Abstract 2311: Cell-free DNA from bronchoalveolar lavage fluid (BALF) for the identification of lung cancer: A new medium of liquid biopsy

Junhong Jiang, Chuanyong Mu, Jun Zhao, Daxiong Zeng, Changguo Wang, Junyi Ye, Jiayue Xu, Jing Su, Han Han-Zhang, Bingsi Li, Haiyan Li, Zhihong Zhang

Cancer Res (2020) 80 (16_Supplement): 2311.

https://doi.org/10.1158/1538-7445.AM2020-2311

Published: 15 August 2020

View articletitled, Abstract 2311: Cell-free DNA from bronchoalveolar lavage fluid (BALF) for the identification of lung cancer: A new medium of liquid biopsy

Journal Articles

A Bis-Indole–Derived NR4A1 Antagonist Induces PD-L1 Degradation and Enhances Antitumor Immunity

Keshav Karki, Gus A. Wright, Kumaravel Mohankumar, Un-Ho Jin, Xing-Han Zhang, Stephen Safe

Cancer Res (2020) 80 (5): 1011–1023.

https://doi.org/10.1158/0008-5472.CAN-19-2314

Published: 02 March 2020

View articletitled, A Bis-Indole–Derived NR4A1 Antagonist Induces PD-L1 Degradation and Enhances Antitumor Immunity

Includes: Supplementary data

Journal Articles

Abstract 816: DNA methylation profiling from circulating tumor DNA for early diagnosis of non-small cell lung cancer

Naixin Liang, Bingsi Li, Chenyang Wang, Tao Zheng, Jiayue Xu, Shuai Fang, Fujun Qiu, Jing Su, Lichen Zhang, Xin Lu, Miaomiao Song, Lingjian Yang, Han Han-Zhang, Xinru Mao, Hao Liu, Shanqing Li, Ke Ma, Zhihong Zhang

Cancer Res (2019) 79 (13_Supplement): 816.

https://doi.org/10.1158/1538-7445.AM2019-816

Published: 01 July 2019

View articletitled, Abstract 816: DNA methylation profiling from circulating tumor DNA for early diagnosis of non-small cell lung cancer

Journal Articles

Abstract 1325: TPX-0022, a polypharmacology inhibitor of MET/CSF1R/SRC inhibits tumor growth by promoting anti-tumor immune responses

Wei Deng, Dayong Zhai, Evan Rogers, Xin Zhang, Dong Lee, Jane Ung, Han Zhang, Jing Liu, Yuelie Lu, John Huang, Armin Graber, Zach Zimmerman, John Lim, Jeffrey Whitten, J. Jean Cui

Cancer Res (2019) 79 (13_Supplement): 1325.

https://doi.org/10.1158/1538-7445.AM2019-1325

Published: 01 July 2019

View articletitled, Abstract 1325: TPX-0022, a polypharmacology inhibitor of MET/CSF1R/SRC inhibits tumor growth by promoting anti-tumor immune responses

Journal Articles

Abstract 1321: TPX-0022, a polypharmacology inhibitor of MET/CSF1R/SRC for treatment of cancers with abnormal HGF/MET signaling

Dayong Zhai, Evan Rogers, Wei Deng, Xin Zhang, Dong Lee, Jane Ung, Han Zhang, Jing Liu, Yuelie Lu, John Huang, Armin Graber, Zach Zimmerman, John Lim, Jeffrey Whitten, J. Jean Cui

Cancer Res (2019) 79 (13_Supplement): 1321.

https://doi.org/10.1158/1538-7445.AM2019-1321

Published: 01 July 2019

View articletitled, Abstract 1321: TPX-0022, a polypharmacology inhibitor of MET/CSF1R/SRC for treatment of cancers with abnormal HGF/MET signaling

Journal Articles

Abstract 242: Large pathway and gene set analysis of GWAS data identifies novel associations for pancreatic cancer

Cancer Res (2018) 78 (13_Supplement): 242.

https://doi.org/10.1158/1538-7445.AM2018-242

Published: 01 July 2018

View articletitled, Abstract 242: Large pathway and gene set analysis of GWAS data identifies novel associations for pancreatic cancer

Journal Articles

Landscape of Combination Immunotherapy and Targeted Therapy to Improve Cancer Management

Leandro M. Colli, Mitchell J. Machiela, Han Zhang, Timothy A. Myers, Lea Jessop, Olivier Delattre, Kai Yu, Stephen J. Chanock

Cancer Res (2017) 77 (13): 3666–3671.

https://doi.org/10.1158/0008-5472.CAN-16-3338

Published: 02 July 2017

View articletitled, Landscape of Combination Immunotherapy and Targeted Therapy to Improve Cancer Management

Includes: Supplementary data

Journal Articles

TG2 and NF-κB Signaling Coordinates the Survival of Mantle Cell Lymphoma Cells via IL6-Mediated Autophagy

Han Zhang, Zheng Chen, Roberto N. Miranda, L. Jeffrey Medeiros, Nami McCarty

Cancer Res (2016) 76 (21): 6410–6423.

https://doi.org/10.1158/0008-5472.CAN-16-0595

Published: 31 October 2016

View articletitled, TG2 and NF-κB Signaling Coordinates the Survival of Mantle Cell Lymphoma Cells via IL6-Mediated Autophagy

Includes: Supplementary data

Journal Articles

Abstract 1193: Treatment of breast cancer xenografts with paclitaxel enriches for cancer stem cells that can be targeted by a ROR1-specific antibody

Suping Zhang, Grace Liu, Sam H. Lai, Han Zhang, Emanuela M. Ghia, Bing Cui, Rongrong Wu, George Widhopf, Jian Yu, Richard Schwab, Karen Messer, Barbara Parker, Thomas J. Kipps

Cancer Res (2016) 76 (14_Supplement): 1193.

https://doi.org/10.1158/1538-7445.AM2016-1193

Published: 15 July 2016

View articletitled, Abstract 1193: Treatment of breast cancer xenografts with paclitaxel enriches for cancer stem cells that can be targeted by a ROR1-specific antibody

Journal Articles

Abstract 4622: Common genetic variants in epigenetic machinery genes and risk of upper gastrointestinal cancers

Cancer Res (2015) 75 (15_Supplement): 4622.

https://doi.org/10.1158/1538-7445.AM2015-4622

Published: 01 August 2015

View articletitled, Abstract 4622: Common genetic variants in epigenetic machinery genes and risk of upper gastrointestinal cancers

Journal Articles

Abstract 2203: Pathway analysis of genome-wide association study data highlights taste transduction and metabolic pathways and esophageal squamous cell carcinoma susceptibility

Cancer Res (2014) 74 (19_Supplement): 2203.

https://doi.org/10.1158/1538-7445.AM2014-2203

Published: 01 October 2014

View articletitled, Abstract 2203: Pathway analysis of genome-wide association study data highlights taste transduction and metabolic pathways and esophageal squamous cell carcinoma susceptibility

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Abstract 4768: Development of fully human TCR-mimic antibodies targeting intracellular tumor antigens using humanized RenTCR-mimic transgenic mice

Abstract 3861: Associations of intragenic rearrangement burden with immune cell infiltration and response to immune checkpoint blockade in cancer

Abstract 2127: TERT C228T and KDM6A alterations are potential predictive biomarkers in non-muscle-invasive bladder cancer treated with intravesical Bacillus Calmette-Guérin instillation

Abstract 1469: TPX-0131, a potent inhibitor of wild type ALK and a broad spectrum of both single and compound ALK resistance mutations

Genome-Wide Association Study Data Reveal Genetic Susceptibility to Chronic Inflammatory Intestinal Diseases and Pancreatic Ductal Adenocarcinoma Risk

Abstract CT127: A phase I study of cMET inhibitor bozitinib in patients with advanced NSCLC harboring cMET alterations

Abstract 5226: TPX-0131: A next generation macrocyclic ALK inhibitor that overcomes ALK resistant mutations refractory to current approved ALK inhibitors

Abstract 4899: Investigating mutation co-operativity in early tumorigenesis of low-grade serous ovarian carcinoma with organoid model system and single-cell RNA sequencing

Abstract 2302: Methylation profiling of circulating tumor DNA for the detection of ovarian cancer

Abstract 2311: Cell-free DNA from bronchoalveolar lavage fluid (BALF) for the identification of lung cancer: A new medium of liquid biopsy

A Bis-Indole–Derived NR4A1 Antagonist Induces PD-L1 Degradation and Enhances Antitumor Immunity

Abstract 816: DNA methylation profiling from circulating tumor DNA for early diagnosis of non-small cell lung cancer

Abstract 1325: TPX-0022, a polypharmacology inhibitor of MET/CSF1R/SRC inhibits tumor growth by promoting anti-tumor immune responses

Abstract 1321: TPX-0022, a polypharmacology inhibitor of MET/CSF1R/SRC for treatment of cancers with abnormal HGF/MET signaling

Abstract 242: Large pathway and gene set analysis of GWAS data identifies novel associations for pancreatic cancer

Landscape of Combination Immunotherapy and Targeted Therapy to Improve Cancer Management

TG2 and NF-κB Signaling Coordinates the Survival of Mantle Cell Lymphoma Cells via IL6-Mediated Autophagy

Abstract 1193: Treatment of breast cancer xenografts with paclitaxel enriches for cancer stem cells that can be targeted by a ROR1-specific antibody

Abstract 4622: Common genetic variants in epigenetic machinery genes and risk of upper gastrointestinal cancers

Abstract 2203: Pathway analysis of genome-wide association study data highlights taste transduction and metabolic pathways and esophageal squamous cell carcinoma susceptibility

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