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Journal Articles

Abstract 3779: LY4050784, a selective inhibitor of SMARCA2, demonstrates synergistic activity in combinations with pembrolizumab or KRAS inhibitors

Free
Nathan A. Brooks, Shuang Chen, Candace Langan, Bryan Perria, Bonita D. Jones, Hai Hu, Mia Lei, Renan Escalante Chong, Wei Zheng, Rowena Almonte-Baldonado, Xiaodong Huang, Robert Stephen Flack, Janice Y. Lee, Kevin Wilson, Anke Klippel, Laurie LeBrun
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3779.
https://doi.org/10.1158/1538-7445.AM2025-3779
Published: 21 April 2025
View articletitled, Abstract 3779: LY4050784, a selective inhibitor of SMARCA2, demonstrates synergistic activity in combinations with pembrolizumab or KRAS inhibitors
Journal Articles

Abstract 191: Functional role of chromosome 1q loci on breast cancer progression

Free
Alakesh Bera, Eric Russ, Hai Hu, Craig D. Shriver, Meera Srivastava
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 191.
https://doi.org/10.1158/1538-7445.AM2025-191
Published: 21 April 2025
View articletitled, Abstract 191: Functional role of chromosome 1q loci on breast cancer progression
Journal Articles

Abstract PO3-13-10: Proteogenomic characterization of primary invasive breast tumors from young women compared to matched tumors from older women

Free
Praveen Kumar Raj Kumar, Jianfang Liu, Anthony Soltis, Nicholas Bateman, Qingrong Chen, Lori Sturtz, Brenda Deyarmin, Mariaelena Pierobon, Tamara Abulez, Anupama Praveen-Kumar, Xijun Zhang, Trinh Nguyen, Chunhua Yan, Ying Hu, Kate Guion, Jeffrey Hooke, Albert Kovatich, Leigh Fantacone-Campbell, Brad Mostoller, Leonid Kvecher, Stella Somiari, Patricia Steeg, Sheila Rajagopal, Kathleen Darcy, Jerry Lee, Clifton Dalgard, Thomas Conrads, Emanuel Petricoin, Daoud Meerzaman, Matthew Wilkerson, APOLLO Research Network, Xiaoying Lin, Craig Shriver, Stanley Lipkowitz, Hai Hu
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO3-13-10.
https://doi.org/10.1158/1538-7445.SABCS23-PO3-13-10
Published: 02 May 2024
View articletitled, Abstract PO3-13-10: Proteogenomic characterization of primary invasive breast tumors from young women compared to matched tumors from older women
Journal Articles

Abstract PO2-16-04: Proteogenomic characterization of non-luminal A versus luminal A breast cancer tumor cells enriched by laser microdissection

Free
Praveen Kumar Raj Kumar, Xiaoying Lin, Tao Liu, Lori Sturtz, Marina Gritsenko, Vladislav Petyuk, Tyler Sagendorf, Brenda Deyarmin, Jianfang Liu, Anupama Praveen-Kumar, Guisong Wang, Jason McDermott, Anil Shukla, Ronald Moore, Matthew Monroe, Bobbie-Jo Webb-Robertson, Jeffrey Hooke, Leigh Fantacone-Campbell, Brad Mostoller, Leonid Kvecher, Jennifer Kane, Jennifer Melley, Stella Somiari, Patrick Soon-Shiong, Richard Smith, Richard Mural, Karin Rodland, Craig Shriver, Albert Kovatich, Hai Hu
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO2-16-04.
https://doi.org/10.1158/1538-7445.SABCS23-PO2-16-04
Published: 02 May 2024
View articletitled, Abstract PO2-16-04: Proteogenomic characterization of non-luminal A versus luminal A breast cancer tumor cells enriched by laser microdissection
Journal Articles

Abstract 6402: Treatment resistance and survival prediction using a machine learning gene expression signature in pancreatic adenocarcinoma

Free
Jianfang Liu, Xiaoying Lin, Craig D. Shriver, Hai Hu
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6402.
https://doi.org/10.1158/1538-7445.AM2024-6402
Published: 22 March 2024
View articletitled, Abstract 6402: Treatment resistance and survival prediction using a machine learning gene expression signature in pancreatic adenocarcinoma
Journal Articles

Abstract 779: Functional role of TGF-beta receptor type-2 in breast cancer progression and survival

Free
Meera Srivastava, Alakesh Bera, Harvey B. Pollard, Hai Hu, Craig D. Shriver
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 779.
https://doi.org/10.1158/1538-7445.AM2024-779
Published: 22 March 2024
View articletitled, Abstract 779: Functional role of TGF-beta receptor type-2 in breast cancer progression and survival
Journal Articles

Genome-Wide CRISPR Screens Identify Multiple Synthetic Lethal Targets That Enhance KRASG12C Inhibitor Efficacy

Available to Purchase
Suman Mukhopadhyay, Hsin-Yi Huang, Ziyan Lin, Michela Ranieri, Shuai Li, Soumyadip Sahu, Yingzhuo Liu, Yi Ban, Kayla Guidry, Hai Hu, Alfonso Lopez, Fiona Sherman, Yi Jer Tan, Yeuan Ting Lee, Amanda P. Armstrong, Igor Dolgalev, Priyanka Sahu, Tinghu Zhang, Wenchao Lu, Nathanael S. Gray, James G. Christensen, Tracy T. Tang, Vamsidhar Velcheti, Alireza Khodadadi-Jamayran, Kwok-Kin Wong, Benjamin G. Neel
Journal: Cancer Research
Cancer Res (2023) 83 (24): 4095–4111.
https://doi.org/10.1158/0008-5472.CAN-23-2729
Published: 15 December 2023
View articletitled, Genome-Wide CRISPR Screens Identify Multiple Synthetic Lethal Targets That Enhance KRASG12C Inhibitor Efficacy
Open the PDF for Genome-Wide CRISPR Screens Identify Multiple Synthetic Lethal Targets That Enhance KRASG12C Inhibitor Efficacy in another window
Includes: Supplementary data
Journal Articles

Abstract 3352: Development and validation of a serum microRNA-based diagnostic model for early detection of multiple cancers

Free
Grace Zhou, Hai Hu
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3352.
https://doi.org/10.1158/1538-7445.AM2023-3352
Published: 04 April 2023
View articletitled, Abstract 3352: Development and validation of a serum microRNA-based diagnostic model for early detection of multiple cancers
Journal Articles

Abstract 807: Inflammatory biomarkers: Breast cancer survival and possible role in COVID-19 associated comorbidity

Free
Alakesh Bera, Eric Russ, Surya Radhakrishnan, Hai Hu, COL Craig D. Shriver, Meera Srivastava
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 807.
https://doi.org/10.1158/1538-7445.AM2023-807
Published: 04 April 2023
View articletitled, Abstract 807: Inflammatory biomarkers: Breast cancer survival and possible role in COVID-19 associated comorbidity
Journal Articles

Abstract P2-11-13: High PD-L2 Protein Expression in Cancer Cells is an Independent Marker of Unfavorable Prognosis in Luminal Breast Tumors

Free
Lubna N. Chaudhary, Inna Chervoneva, Amy R. Peck, Yunguang Sun, Misung Yi, John F. Langenheim, Julie M. Jorns, Sailaja Kamaraju, Yee Chung Cheng, John Burfeind, Christopher R. Chitambar, Jeffrey A. Hooke, Albert J. Kovatich, Craig Shriver, Hai Hu, Juan P. Palazzo, Marluce Bibbo, Terry Hyslop, Richard Pestell, Edith P. Mitchell, Hallgeir Rui
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P2-11-13.
https://doi.org/10.1158/1538-7445.SABCS22-P2-11-13
Published: 01 March 2023
View articletitled, Abstract P2-11-13: High PD-L2 Protein Expression in Cancer Cells is an Independent Marker of Unfavorable Prognosis in Luminal Breast Tumors
Journal Articles

Abstract 5828: Functional role of long non-coding RNA YTHDF3-AS1 in breast cancer

Free
Alakesh Bera, Surya Radhakrishnan, Eric Russ, Diya Biswas, Madhan Subramanian, Harvey B. Pollard, Hai Hu, Craig D. Shriver, Roopa Biswas, Meera Srivastava
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5828.
https://doi.org/10.1158/1538-7445.AM2022-5828
Published: 15 June 2022
View articletitled, Abstract 5828: Functional role of long non-coding RNA YTHDF3-AS1 in breast cancer
Journal Articles

Abstract 5411: Association of treatment response, recurrence and underlying molecular mechanism for over 22 TCGA cancer types

Free
Jianfang Liu, Peter T. Hu, Praveen-Kumar Raj-Kumar, Anupama Praveen-Kumar, Xiaoying Lin, Craig D. Shriver, Hai Hu
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5411.
https://doi.org/10.1158/1538-7445.AM2022-5411
Published: 15 June 2022
View articletitled, Abstract 5411: Association of treatment response, recurrence and underlying molecular mechanism for over 22 TCGA cancer types
Journal Articles

Abstract 5931: Development and validation of a novel circulating cell-free microRNA diagnostic model with high accuracy for multi-cancer early detection

Free
Andrew Zhang, Hai Hu
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5931.
https://doi.org/10.1158/1538-7445.AM2022-5931
Published: 15 June 2022
View articletitled, Abstract 5931: Development and validation of a novel circulating cell-free microRNA diagnostic model with high accuracy for multi-cancer early detection
Journal Articles

Abstract 1356: In vivo epigenetic CRISPR screen identifies PRMT5 as an immune suppressor in pancreatic cancer

Free
Hai Hu, Jiehui Deng, Fei Li, wei wang, Alireza Khodadadi-Jamayran
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1356.
https://doi.org/10.1158/1538-7445.AM2022-1356
Published: 15 June 2022
View articletitled, Abstract 1356: In vivo epigenetic CRISPR screen identifies PRMT5 as an immune suppressor in pancreatic cancer
Journal Articles

Abstract 3363: Clinicopathologic factors associated with surgical margins in primary invasive breast cancer

Free
Anupama Praveen Kumar, Diego Vicente, Praveen Kumar Raj Kumar, Jianfang Liu, Brenda Deyarmin, Brad Mostoller, Albert J. Kovatich, Jeffrey A. Hooke, Leigh Fantacone-Campbell, Xiaoying Lin, Craig D. Shriver, Hai Hu
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3363.
https://doi.org/10.1158/1538-7445.AM2022-3363
Published: 15 June 2022
View articletitled, Abstract 3363: Clinicopathologic factors associated with surgical margins in primary invasive breast cancer
Journal Articles

Abstract P1-05-04: Novel breast cancer proteomic subtyping with connection to cell of origin

Free
Guisong Wang, Punit Shah, Rick Searfoss, J. Leigh Fantacone-Campbell, Jeffrey A. Hooke, Brenda Deyarmin, Rebecca N. Zingmark, Stella Somiari, Jianfang Liu, Leonid Kvecher, Lori A. Sturtz, Praveen-Kumar Raj-Kumar, Elder Granger, Linda Vahdat, Niven R. Narain, Mary L. Cutler, Rangaprasad Sarangarajan, Hai Hu, Michael A. Kiebish, Albert J. Kovatich, Craig D. Shriver
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P1-05-04.
https://doi.org/10.1158/1538-7445.SABCS21-P1-05-04
Published: 15 February 2022
View articletitled, Abstract P1-05-04: Novel breast cancer proteomic subtyping with connection to cell of origin
Journal Articles

LncRNA Uc003xsl.1-Mediated Activation of the NFκB/IL8 Axis Promotes Progression of Triple-Negative Breast Cancer

Open Access
Ying Xu, Wei Ren, Qingjian Li, Chaohui Duan, Xiaorong Lin, Zhuofei Bi, Kaiyun You, Qian Hu, Ning Xie, Yunfang Yu, Xiaoding Xu, Hai Hu, Herui Yao
Journal: Cancer Research
Cancer Res (2022) 82 (4): 556–570.
https://doi.org/10.1158/0008-5472.CAN-21-1446
Published: 15 February 2022
View articletitled, LncRNA Uc003xsl.1-Mediated Activation of the NFκB/IL8 Axis Promotes Progression of Triple-Negative Breast Cancer
Open the PDF for LncRNA Uc003xsl.1-Mediated Activation of the NFκB/IL8 Axis Promotes Progression of Triple-Negative Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Targeting HER2 Exon 20 Insertion–Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor Mobocertinib

Open Access
Han Han, Shuai Li, Ting Chen, Michael Fitzgerald, Shengwu Liu, Chengwei Peng, Kwan Ho Tang, Shougen Cao, Johara Chouitar, Jiansheng Wu, David Peng, Jiehui Deng, Zhendong Gao, Theresa E. Baker, Fei Li, Hua Zhang, Yuanwang Pan, Hailin Ding, Hai Hu, Val Pyon, Cassandra Thakurdin, Eleni Papadopoulos, Sittinon Tang, Francois Gonzalvez, Haiquan Chen, Victor M. Rivera, Rachael Brake, Sylvie Vincent, Kwok-Kin Wong
Journal: Cancer Research
Cancer Res (2021) 81 (20): 5311–5324.
https://doi.org/10.1158/0008-5472.CAN-21-1526
Published: 15 October 2021
View articletitled, Targeting HER2 Exon 20 Insertion–Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor Mobocertinib
Open the PDF for Targeting HER2 Exon 20 Insertion–Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor Mobocertinib in another window
Includes: Supplementary data
Journal Articles

Abstract 1188: Reclassification of ER+ (luminal A/luminal B1 minus ER low)-like and ER- like breast tumors based on proteomic/gene and clinical outcome signatures

Free
Guisong Wang, Punit Shah, Rick Searfoss, Leigh Fantacone-Campbell, Jeffrey A. Hooke, Brenda Deyarmin, Rebecca N. Zingmark, Stella Somiari, Jianfang Liu, Leonid Kvecher, Bradley Mostoller, Lori A. Sturtz, Praven-Kumar Raj-Kumar, Elder Granger, Linda Vahdat, Mary L. Cutler, Chas Bountra, Rangaprasad Sarangarajan, Hai Hu, Michael A. Kiebish, Albert J. Kovatich, Niven R. Narain, Craig D. Shriver
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1188.
https://doi.org/10.1158/1538-7445.AM2021-1188
Published: 01 July 2021
View articletitled, Abstract 1188: Reclassification of ER+ (luminal A/luminal B1 minus ER low)-like and ER- like breast tumors based on proteomic/gene and clinical outcome signatures
Journal Articles

Abstract 2342: Multidimensional metabolomic stratification of ER+/HER2- compared to ER-/HER2- breast tumors

Free
Valerie Bussberg, Vladimir Tolstikov, Guisong Wang, Punit Shah, Rick Searfoss, Leigh Fantacone-Campbell, Jeffrey A. Hooke, Brenda Deyarmin, Rebecca N. Zingmark, Stella Somiari, Jianfang Liu, Leonid Kvecher, Bradley Mostoller, Lori Sturtz, Praveen-Kumar Raj-Kumar, Elder Granger, Linda Vahdat, Mary L. Cutler, Chas Bountra, Rangaprasad Sarangarajan, Hai Hu, Albert J. Kovatich, Michael A. Kiebish, Niven R. Narain, Craig D. Shriver
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2342.
https://doi.org/10.1158/1538-7445.AM2021-2342
Published: 01 July 2021
View articletitled, Abstract 2342: Multidimensional metabolomic stratification of ER+/HER2- compared to ER-/HER2- breast tumors