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H-J. Su Huang
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Journal Articles

Krüppel-like factor 6 regulates melanoma progression in a type I collagen-rich environment.

Sung Jin Huh, Yen Chen, Scott Friedman, H-J. Su Huang, Webster Cavenee, Gavin Robertson
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 2454.
Published: 01 May 2007
View article titled, Krüppel-like factor 6 regulates melanoma progression in a type I collagen-rich environment.
Journal Articles

Mutant Epidermal Growth Factor Receptor Signaling Down-Regulates p27 through Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway in Glioblastomas

Yoshitaka Narita, Motoo Nagane, Kazuhiko Mishima, H-J. Su Huang, Frank B. Furnari, Webster K. Cavenee
Journal: Cancer Research
Cancer Res (2002) 62 (22): 6764–6769.
Published: 15 November 2002
View article titled, Mutant Epidermal Growth Factor Receptor Signaling Down-Regulates p27 through Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway in Glioblastomas
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Journal Articles

Vascular Endothelial Growth Factor Isoforms Display Distinct Activities in Promoting Tumor Angiogenesis at Different Anatomic Sites

Ping Guo, Li Xu, Shi Pan, Rolf A. Brekken, Shu-Ting Yang, G. Brian Whitaker, Motoo Nagane, Philip E. Thorpe, Jan S. Rosenbaum, H.-J. Su Huang, Webster K. Cavenee, Shi-Yuan Cheng
Journal: Cancer Research
Cancer Res (2001) 61 (23): 8569–8577.
Published: 01 December 2001
View article titled, Vascular Endothelial Growth Factor Isoforms Display Distinct Activities in Promoting Tumor Angiogenesis at Different Anatomic Sites
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Journal Articles

Monoclonal Antibody 806 Inhibits the Growth of Tumor Xenografts Expressing Either the de2–7 or Amplified Epidermal Growth Factor Receptor (EGFR) but not Wild-Type EGFR

Rodney B. Luwor, Terrance G. Johns, Carmel Murone, H-J. Su Huang, Webster K. Cavenee, Gerd Ritter, Lloyd J. Old, Antony W. Burgess, Andrew M. Scott
Journal: Cancer Research
Cancer Res (2001) 61 (14): 5355–5361.
Published: 01 July 2001
View article titled, Monoclonal Antibody 806 Inhibits the Growth of Tumor Xenografts Expressing Either the de2–7 or Amplified Epidermal Growth Factor Receptor (EGFR) but not Wild-Type EGFR
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Journal Articles

Growth Suppression of Intracranial Xenografted Glioblastomas Overexpressing Mutant Epidermal Growth Factor Receptors by Systemic Administration of Monoclonal Antibody (mAb) 806, a Novel Monoclonal Antibody Directed to the Receptor

Kazuhiko Mishima, Terrance G. Johns, Rodney B. Luwor, Andrew M. Scott, Elisabeth Stockert, Achim A. Jungbluth, Xiang-Dong Ji, Padma Suvarna, Joseph R. Voland, Lloyd J. Old, H-J. Su Huang, Webster K. Cavenee
Journal: Cancer Research
Cancer Res (2001) 61 (14): 5349–5354.
Published: 01 July 2001
View article titled, Growth Suppression of Intracranial Xenografted Glioblastomas Overexpressing Mutant Epidermal Growth Factor Receptors by Systemic Administration of Monoclonal Antibody (mAb) 806, a Novel Monoclonal Antibody Directed to the Receptor
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Journal Articles

Increased Death Receptor 5 Expression by Chemotherapeutic Agents in Human Gliomas Causes Synergistic Cytotoxicity with Tumor Necrosis Factor-related Apoptosis-inducing Ligand in Vitro and in Vivo

Motoo Nagane, Guohua Pan, Jessie J. Weddle, Vishva M. Dixit, Webster K. Cavenee, H.-J. Su Huang
Journal: Cancer Research
Cancer Res (2000) 60 (4): 847–853.
Published: 01 February 2000
View article titled, Increased Death Receptor 5 Expression by Chemotherapeutic Agents in Human Gliomas Causes Synergistic Cytotoxicity with Tumor Necrosis Factor-related Apoptosis-inducing Ligand <em>in Vitro</em> and <em>in Vivo</em>
Open the PDF for Increased Death Receptor 5 Expression by Chemotherapeutic Agents in Human Gliomas Causes Synergistic Cytotoxicity with Tumor Necrosis Factor-related Apoptosis-inducing Ligand <em>in Vitro</em> and <em>in Vivo</em> in another window
Journal Articles

Expression of the Ets-1 Transcription Factor in Human Astrocytomas Is Associated with Fms-like Tyrosine Kinase-1 (Flt-1)/Vascular Endothelial Growth Factor Receptor-1 Synthesis and Neoangiogenesis

Markus M. Valter, Anja Hügel, H-J. Su Huang, Webster K. Cavenee, Otmar D. Wiestler, Torsten Pietsch, Nicolas Wernert
Journal: Cancer Research
Cancer Res (1999) 59 (21): 5608–5614.
Published: 01 November 1999
View article titled, Expression of the Ets-1 Transcription Factor in Human Astrocytomas Is Associated with Fms-like Tyrosine Kinase-1 (Flt-1)/Vascular Endothelial Growth Factor Receptor-1 Synthesis and Neoangiogenesis
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Journal Articles

The Chromosome 10 Monosomy Common in Human Melanomas Results from the Loss of Two Separate Tumor Suppressor Loci

Gavin P. Robertson, Rudolf A. Herbst, Motoo Nagane, H-J. Su Huang, Webster K. Cavenee
Journal: Cancer Research
Cancer Res (1999) 59 (15): 3596–3601.
Published: 01 August 1999
View article titled, The Chromosome 10 Monosomy Common in Human Melanomas Results from the Loss of Two Separate Tumor Suppressor Loci
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Journal Articles

Induction of Vascular Endothelial Growth Factor Expression in Endothelial Cells by Platelet-derived Growth Factor through the Activation of Phosphatidylinositol 3-Kinase

Degui Wang, H-J. Su Huang, Andrius Kazlauskas, Webster K. Cavenee
Journal: Cancer Research
Cancer Res (1999) 59 (7): 1464–1472.
Published: 01 April 1999
View article titled, Induction of Vascular Endothelial Growth Factor Expression in Endothelial Cells by Platelet-derived Growth Factor through the Activation of Phosphatidylinositol 3-Kinase
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Journal Articles

The Phosphoinositol Phosphatase Activity of PTEN Mediates a Serum-sensitive G1 Growth Arrest in Glioma Cells

Frank B. Furnari, H-J. Su Huang, Webster K. Cavenee
Journal: Cancer Research
Cancer Res (1998) 58 (22): 5002–5008.
Published: 01 November 1998
View article titled, The Phosphoinositol Phosphatase Activity of <em>PTEN</em> Mediates a Serum-sensitive G<sub>1</sub> Growth Arrest in Glioma Cells
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Journal Articles

Absence of PTEN/MMAC1 Germ-Line Mutations in Sporadic Bannayan-Riley-Ruvalcaba Syndrome

John M. Carethers, Frank B. Furnari, Andrew F. Zigman, Joel E. Lavine, Marilyn C. Jones, Gail E. Graham, Ahmad S. Teebi, H-J. Su Huang, Hannah T. Ha, Dharam P. Chauhan, Christina L. Chang, Webster K. Cavenee, C. Richard Boland
Journal: Cancer Research
Cancer Res (1998) 58 (13): 2724–2726.
Published: 01 July 1998
View article titled, Absence of <em>PTEN/MMAC1</em> Germ-Line Mutations in Sporadic Bannayan-Riley-Ruvalcaba Syndrome
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Journal Articles

Cyclin-dependent Kinase 6 (CDK6) Amplification in Human Gliomas Identified Using Two-dimensional Separation of Genomic DNA

Joseph F. Costello, Christoph Plass, Wadih Arap, Verne M. Chapman, William A. Held, Mitchel S. Berger, H-J. Su Huang, Webster K. Cavenee
Journal: Cancer Research
Cancer Res (1997) 57 (7): 1250–1254.
Published: 01 April 1997
View article titled, Cyclin-dependent Kinase 6 (CDK6) Amplification in Human Gliomas Identified Using Two-dimensional Separation of Genomic DNA
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Journal Articles

A Common Mutant Epidermal Growth Factor Receptor Confers Enhanced Tumorigenicity on Human Glioblastoma Cells by Increasing Proliferation and Reducing Apoptosis

Motoo Nagane, Frank Coufal, Hong Lin, Oliver Bögler, Webster K. Cavenee, H-J. Su Huang
Journal: Cancer Research
Cancer Res (1996) 56 (21): 5079–5086.
Published: 01 November 1996
View article titled, A Common Mutant Epidermal Growth Factor Receptor Confers Enhanced Tumorigenicity on Human Glioblastoma Cells by Increasing Proliferation and Reducing Apoptosis
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Journal Articles

Tyrphostin AG 1478 Preferentially Inhibits Human Glioma Cells Expressing Truncated Rather than Wild-Type Epidermal Growth Factor Receptors

Yuchun Han, Cornelio Gacusana Caday, Anil Nanda, Webster K. Cavenee, H-J. Su Huang
Journal: Cancer Research
Cancer Res (1996) 56 (17): 3859–3861.
Published: 01 September 1996
View article titled, Tyrphostin AG 1478 Preferentially Inhibits Human Glioma Cells Expressing Truncated Rather than Wild-Type Epidermal Growth Factor Receptors
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Journal Articles

Silencing of p16/CDKN2 Expression in Human Gliomas by Methylation and Chromatin Condensation

Joseph F. Costello, Mitchel S. Berger, H-J. Su Huang, Webster K. Cavenee
Journal: Cancer Research
Cancer Res (1996) 56 (10): 2405–2410.
Published: 01 May 1996
View article titled, Silencing of <em>p16/CDKN2</em> Expression in Human Gliomas by Methylation and Chromatin Condensation
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Journal Articles

Loss of Wild-Type p53 Bestows a Growth Advantage on Primary Cortical Astrocytes and Facilitates Their in Vitro Transformation

Oliver Bögler, H-J. Su Huang, Webster K. Cavenee
Journal: Cancer Research
Cancer Res (1995) 55 (13): 2746–2751.
Published: 01 July 1995
View article titled, Loss of Wild-Type <em>p53</em> Bestows a Growth Advantage on Primary Cortical Astrocytes and Facilitates Their <em>in Vitro</em> Transformation
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Journal Articles

Loss of P16INK4 Expression Is Frequent in High Grade Gliomas

Ryo Nishikawa, Frank B. Furnari, Hong Lin, Wadih Arap, Mitchel S. Berger, Webster K. Cavenee, H-J. Su Huang
Journal: Cancer Research
Cancer Res (1995) 55 (9): 1941–1945.
Published: 01 May 1995
View article titled, Loss of P16<sup>INK4</sup> Expression Is Frequent in High Grade Gliomas
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Journal Articles

Replacement of the p16/CDKN2 Gene Suppresses Human Glioma Cell Growth

Wadih Arap, Ryo Nishikawa, Frank B. Furnari, Webster K. Cavenee, H-J. Su Huang
Journal: Cancer Research
Cancer Res (1995) 55 (6): 1351–1354.
Published: 01 March 1995
View article titled, Replacement of the <em>p16/CDKN2</em> Gene Suppresses Human Glioma Cell Growth
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Journal Articles

Analysis of the p53 Gene and Its Expression in Human Glioblastoma Cells

Erwin G. Van Meir, Tetsuro Kikuchi, Mitsuhiro Tada, Hong Li, Annie-Claire Diserens, Brian E. Wojcik, H-J. Su Huang, Theodore Friedmann, Nicolas de Tribolet, Webster K. Cavenee
Journal: Cancer Research
Cancer Res (1994) 54 (3): 649–652.
Published: 01 February 1994
View article titled, Analysis of the <em>p53</em> Gene and Its Expression in Human Glioblastoma Cells
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