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Journal Articles

Mcl-1 Interacts with Akt to Promote Lung Cancer Progression

Guo Chen, Dongkyoo Park, Andrew T. Magis, Madhusmita Behera, Suresh S. Ramalingam, Taofeek K. Owonikoko, Gabriel L. Sica, Keqiang Ye, Chao Zhang, Zhengjia Chen, Walter J. Curran, Xingming Deng
Journal: Cancer Research
Cancer Res (2019) 79 (24): 6126–6138.
https://doi.org/10.1158/0008-5472.CAN-19-0950
Published: 13 December 2019
View article titled, Mcl-1 Interacts with Akt to Promote Lung Cancer Progression
Open the PDF for Mcl-1 Interacts with Akt to Promote Lung Cancer Progression in another window
Includes: Supplementary data
Journal Articles

Aberrant FGFR Tyrosine Kinase Signaling Enhances the Warburg Effect by Reprogramming LDH Isoform Expression and Activity in Prostate Cancer

Junchen Liu, Guo Chen, Zezhen Liu, Shaoyou Liu, Zhiduan Cai, Pan You, Yuepeng Ke, Li Lai, Yun Huang, Hongchang Gao, Liangcai Zhao, Helene Pelicano, Peng Huang, Wallace L. McKeehan, Chin-Lee Wu, Cong Wang, Weide Zhong, Fen Wang
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (16): 4459–4470.
https://doi.org/10.1158/0008-5472.CAN-17-3226
Published: 14 August 2018
View article titled, Aberrant FGFR Tyrosine Kinase Signaling Enhances the Warburg Effect by Reprogramming LDH Isoform Expression and Activity in Prostate Cancer
Open the PDF for Aberrant FGFR Tyrosine Kinase Signaling Enhances the Warburg Effect by Reprogramming LDH Isoform Expression and Activity in Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 328: Targeting Mcl-1 enhances DNA replication stress sensitivity for cancer therapy

Guo Chen, Andrew Magis, Ke Xu, Dongkyoo Park, David Yu, Taofeek Owonikoko, Gabriel Sica, Sarah Satola, Suresh Ramalingam, Walter Curran, Paul Doetsch, Xingming Deng
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 328.
https://doi.org/10.1158/1538-7445.AM2018-328
Published: 01 July 2018
View article titled, Abstract 328: Targeting Mcl-1 enhances DNA replication stress sensitivity for cancer therapy
Journal Articles

Abstract 725: Targeting the skin microenvironment for effective cancer vaccines

Jack R. You, Rong Hao, Louis D. Falo, Guo Chen, Xingxing Hao, Cara Carey, Zhaoyang You, Louis D. Falo
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 725.
https://doi.org/10.1158/1538-7445.AM2018-725
Published: 01 July 2018
View article titled, Abstract 725: Targeting the skin microenvironment for effective cancer vaccines
Journal Articles

Abstract 2333: Modulation of Bax and mTOR for cancer therapeutics

Rui Li, Chunyong Ding, Jun Zhang, Maohua Xie, Dongkyoo Park, Ye Ding, Guo Chen, Guojing Zhang, Melissa Gilbert-Ross, Wei Zhou, Adam Marcus, Shi-Yong Sun, Zhuo Chen, Gabriel Sica, Suresh Ramalingam, Andrew Magis, Haian Fu, Fadlo Khuri, Walter Curran, Taofeek Owonikoko, Dong Shin, Jia Zhou, Xingming Deng
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2333.
https://doi.org/10.1158/1538-7445.AM2017-2333
Published: 01 July 2017
View article titled, Abstract 2333: Modulation of Bax and mTOR for cancer therapeutics
Journal Articles

Modulation of Bax and mTOR for Cancer Therapeutics

Rui Li, Chunyong Ding, Jun Zhang, Maohua Xie, Dongkyoo Park, Ye Ding, Guo Chen, Guojing Zhang, Melissa Gilbert-Ross, Wei Zhou, Adam I. Marcus, Shi-Yong Sun, Zhuo G. Chen, Gabriel L. Sica, Suresh S. Ramalingam, Andrew T. Magis, Haian Fu, Fadlo R. Khuri, Walter J. Curran, Taofeek K. Owonikoko, Dong M. Shin, Jia Zhou, Xingming Deng
Journal: Cancer Research
Cancer Res (2017) 77 (11): 3001–3012.
https://doi.org/10.1158/0008-5472.CAN-16-2356
Published: 31 May 2017
View article titled, Modulation of Bax and mTOR for Cancer Therapeutics
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Includes: Supplementary data
Journal Articles

Abstract 4363: Loss of PTEN promotes resistance to T cell-mediated immunotherapy

Weiyi Peng, Jie Qing Chen, Chengwen Liu, Shruti Malu, Caitlin Creasy, Michael Tetzlaff, Chunyu Xu, Jodi McKenzie, Chunlei Zhang, Xiaoxuan Liang, Leila Williams, Wanleng Deng, Guo Chen, Rina Mbofung, Alexander Lazar, Carlos Torres-Cabala, Zachary Cooper, Pei-Ling Chen, Trang Tieu, Stefani Spranger, Xiaoxing Yu, Chantale Bernatchez, Marie-Andree Forget, Cara Haymaker, Rodabe Amaria, Jennifer McQuade, Isabella Glitza, Tina Cascone, Haiyan Li, Lawrence Kwong, Timothy Heffernan, Jianhua Hu, Roland Bassett, Marcus Bosenberg, Scott Woodman, Willem Overwijk, Gregory Lizée, Jason Roszik, Thomas Gajewski, Jennifer Wargo, Jeffrey Gershenwald, Laszlo Radvanyi, Michael Davies, Patrick Hwu
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4363.
https://doi.org/10.1158/1538-7445.AM2016-4363
Published: 15 July 2016
View article titled, Abstract 4363: Loss of PTEN promotes resistance to T cell-mediated immunotherapy
Journal Articles

Abstract 515: Survivin contributes to radiation resistance in head and neck cancer through regulation of DNA damage repair

Xu Wang, Jonathan J. Beitler, Wen Huang, Guo Chen, Sreenivas Nannapaneni, Nabil F. Saba, Xingming Deng, Zhuo G. Chen, Dong M. Shin
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 515.
https://doi.org/10.1158/1538-7445.AM2016-515
Published: 15 July 2016
View article titled, Abstract 515: Survivin contributes to radiation resistance in head and neck cancer through regulation of DNA damage repair
Journal Articles

Abstract 2757: Mcl-1 dictates DNA double-strand break repair pathway choice

Guo Chen, Ke Xu, Maohua Xie, Taofeek K. Owonikoko, Suresh S. Ramalingam, Paul W. Doetsch, Xingming Deng
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2757.
https://doi.org/10.1158/1538-7445.AM2016-2757
Published: 15 July 2016
View article titled, Abstract 2757: Mcl-1 dictates DNA double-strand break repair pathway choice
Journal Articles

Abstract B26: Receptor tyrosine kinase signaling mediates resistance in NRAS mutant melanoma

James Robinson, Vito Rebecca, Guo Chen, Michael Davies, Matthew VanBrocklin, Sheri Holmen
Journal: Cancer Research
Cancer Res (2015) 75 (14_Supplement): B26.
https://doi.org/10.1158/1538-7445.MEL2014-B26
Published: 16 July 2015
View article titled, Abstract B26: Receptor tyrosine kinase signaling mediates resistance in NRAS mutant melanoma
Journal Articles

Inhibition of mTORC1/2 Overcomes Resistance to MAPK Pathway Inhibitors Mediated by PGC1α and Oxidative Phosphorylation in Melanoma

Y.N. Vashisht Gopal, Helen Rizos, Guo Chen, Wanleng Deng, Dennie T. Frederick, Zachary A. Cooper, Richard A. Scolyer, Gulietta Pupo, Kakajan Komurov, Vasudha Sehgal, Jiexin Zhang, Lalit Patel, Cristiano G. Pereira, Bradley M. Broom, Gordon B. Mills, Prahlad Ram, Paul D. Smith, Jennifer A. Wargo, Georgina V. Long, Michael A. Davies
Journal: Cancer Research
Cancer Res (2014) 74 (23): 7037–7047.
https://doi.org/10.1158/0008-5472.CAN-14-1392
Published: 30 November 2014
View article titled, Inhibition of mTORC1/2 Overcomes Resistance to MAPK Pathway Inhibitors Mediated by PGC1α and Oxidative Phosphorylation in Melanoma
Open the PDF for Inhibition of mTORC1/2 Overcomes Resistance to MAPK Pathway Inhibitors Mediated by PGC1α and Oxidative Phosphorylation in Melanoma in another window
Includes: Supplementary data
Journal Articles

Abstract 1381: Reduction in aflatoxin exposure drives decrease in primary liver cancer in Qidong, China.

Patricia A. Egner, Jian-Guo Chen, Derek Ng, Lisa P. Jacobson, Alvaro Munoz, Jian-Hua Lu, Yuan-Rong Zhu, Geng-Sun Qian, Tao-Yang Chen, Felicia Wu, Jian-Min Wang, John D. Groopman, Thomas W. Kensler
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1381.
https://doi.org/10.1158/1538-7445.AM2013-1381
Published: 15 April 2013
View article titled, Abstract 1381: Reduction in aflatoxin exposure drives decrease in primary liver cancer in Qidong, China.
Journal Articles

Abstract 968: Molecular and clinical correlates of PTEN expression in melanoma

Michael A. Davies, Guo Chen, Diane D. Liu, Jared Malke, Jeffrey E. Gershenwald, Alexander J. Lazar
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 968.
https://doi.org/10.1158/1538-7445.AM2012-968
Published: 15 April 2012
View article titled, Abstract 968: Molecular and clinical correlates of PTEN expression in melanoma
Journal Articles

Abstract LB-405: Modulation of the metabolism of air-borne pollutants by broccoli sprout beverages: Results of a short term, cross-over clinical trial in Qidong, People's Republic of China

Patricia A. Egner, Jian Guo Chen, Jin Bing Wang, Marlin D. Friesen, Lisa P. Jacobson, Alvaro Munoz, Derek Ng, Tao Yang Chen, Jed W. Fahey, Paul Talalay, Steven G. Carmella, Stephen S. Hecht, John D. Groopman, Thomas W. Kensler
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): LB-405.
https://doi.org/10.1158/1538-7445.AM2011-LB-405
Published: 15 April 2011
View article titled, Abstract LB-405: Modulation of the metabolism of air-borne pollutants by broccoli sprout beverages: Results of a short term, cross-over clinical trial in Qidong, People's Republic of China
Journal Articles

Predictive power of hepatitis B viral mutations in plasma of chronic carriers for liver cancer development.

Jian Guo Chen, Shuang Yuan Kuang, Patricia Egner, Jian Hua Lu, Yuan Rong Zhu, Jin Bing Wang, Yong Hui Zhang, Tao Yang Chen, Alvaro Munoz, Thomas Kensler, John D. Groopman
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1332–1333.
Published: 15 April 2006
View article titled, Predictive power of hepatitis B viral mutations in plasma of chronic carriers for liver cancer development.