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Journal Articles

Abstract 7161: HMGA2 predicts treatment outcome in pancreatic cancer

Naomi Yamamoto, Stephanie Dobersch, Ian Loveless, Annie Samraj, Gun Ho Jang, Miki Haraguchi, Ryan Fields, David DeNardo, Faiyaz Notta, Howard Crawford, Nina Steele, Sita Kugel

Cancer Res (2025) 85 (8_Supplement_1): 7161.

https://doi.org/10.1158/1538-7445.AM2025-7161

Published: 21 April 2025

View articletitled, Abstract 7161: HMGA2 predicts treatment outcome in pancreatic cancer

Journal Articles

Abstract 3261: Plasma whole-genome sequencing to monitor pancreatic cancer

Cancer Res (2025) 85 (8_Supplement_1): 3261.

https://doi.org/10.1158/1538-7445.AM2025-3261

Published: 21 April 2025

View articletitled, Abstract 3261: Plasma whole-genome sequencing to monitor pancreatic cancer

Journal Articles

Abstract 3161: High throughput drug screening to uncover molecular vulnerabilities in pancreatic ductal adenocarcinoma

Nikta Feizi, Eugenia Flores-Figueroa, Karen Ng, Zhen-Mei Liu, Farnoosh Abbas Aghababazadeh, Gun Ho Jang, Daniela Bevacqua, Stephanie Ramotar, Shawn Hutchinson, Anna Dodd, Julie Wilson, Robert Grant, Ronan Mclaughlin, Erica Tsang, Jennifer Knox, Steven Gallinger, Benjamin Haibe-Kains, Faiyaz Notta

Cancer Res (2025) 85 (8_Supplement_1): 3161.

https://doi.org/10.1158/1538-7445.AM2025-3161

Published: 21 April 2025

View articletitled, Abstract 3161: High throughput drug screening to uncover molecular vulnerabilities in pancreatic ductal adenocarcinoma

Journal Articles

Abstract 1438: HMGA2 and protein leucine methylation drive pancreatic cancer lineage plasticity

Sita Kugel, Stephanie Dobersch, Naomi Yamamoto, Aidan Schutter, Sarah M. Cavender, Tess M. Robertson, Gun Ho Jang, Annie N. Samraj, Ben Doron, Lisa A. Poole, Martine Roudier, Cindy L. Wladyka, Isabel English, Guillermo Barreto, Rosalie Sears, Srivatsan Raghavan, Faiyaz Notta, Robert N. Eisenman, Andrew C. Hsieh

Cancer Res (2025) 85 (8_Supplement_1): 1438.

https://doi.org/10.1158/1538-7445.AM2025-1438

Published: 21 April 2025

View articletitled, Abstract 1438: HMGA2 and protein leucine methylation drive pancreatic cancer lineage plasticity

Journal Articles

MICAL2 Promotes Pancreatic Cancer Growth and Metastasis

Cancer Res (2025) 85 (6): 1049–1063.

https://doi.org/10.1158/0008-5472.CAN-24-0744

Published: 14 March 2025

View articletitled, MICAL2 Promotes Pancreatic Cancer Growth and Metastasis

Includes: Supplementary data

Journal Articles

Abstract A066: nSMase2-mediated exosome secretion shapes the tumor microenvironment to immunologically support pancreatic cancer

Cancer Res (2024) 84 (17_Supplement_2): A066.

https://doi.org/10.1158/1538-7445.PANCREATIC24-A066

Published: 15 September 2024

View articletitled, Abstract A066: nSMase2-mediated exosome secretion shapes the tumor microenvironment to immunologically support pancreatic cancer

Journal Articles

Abstract 6235: Clinical and phenotypic consequences of HLA mediated antigen presentation deficiency in pancreatic adenocarcinoma at bulk and single-cell resolution

Michael J. Geuenich, Barbara Gruenwald, Grainne O'Kane, Chengxin Yu, Tan Tiak Ju, Amy Zhang, Oumaima Hamza, Gun Ho Jang, Faiyaz Notta, Steven Gallinger, Kieran R. Campbell

Cancer Res (2024) 84 (6_Supplement): 6235.

https://doi.org/10.1158/1538-7445.AM2024-6235

Published: 22 March 2024

View articletitled, Abstract 6235: Clinical and phenotypic consequences of HLA mediated antigen presentation deficiency in pancreatic adenocarcinoma at bulk and single-cell resolution

Journal Articles

Abstract A041: Characterizing antigen presentation associated immune escape mechanisms in pancreatic adenocarcinoma using an integrative computational approach

Michael J. Geuenich, Barbara Gruenwald, Amy Zhang, Oumaima Hamza, Gun Ho Jang, Grainne O’Kane, Faiyaz Notta, Steven Gallinger, Kieran R. Campbell

Cancer Res (2024) 84 (2_Supplement): A041.

https://doi.org/10.1158/1538-7445.PANCA2023-A041

Published: 16 January 2024

View articletitled, Abstract A041: Characterizing antigen presentation associated immune escape mechanisms in pancreatic adenocarcinoma using an integrative computational approach

Journal Articles

Abstract C059: Hub gene analysis identifies CAD as a potential mediator for drug resistance in pancreatic cancer

Foram Vyas, Barbara Grünwald, Kazeera Aliar, Gun Ho Jang, Grainne O'Kane, Thomas Kislinger, Steven Gallinger, Benjamin Haibe-Kains, Rama Khokha

Cancer Res (2024) 84 (2_Supplement): C059.

https://doi.org/10.1158/1538-7445.PANCA2023-C059

Published: 16 January 2024

View articletitled, Abstract C059: Hub gene analysis identifies CAD as a potential mediator for drug resistance in pancreatic cancer

Journal Articles

Abstract 173: Genomic characterization of patient-derived pancreatic cancer organoids

Irene Y. Xie, Yuanchang Fang, Amy X. Zhang, Karen Ng, Zhen-Mei Liu, Eugenia Flores-Figueroa, Gun Ho Jang, Stephanie Ramotar, Anna Dodd, Julie Wilson, Jennifer J. Knox, Steven Gallinger, Faiyaz Notta

Cancer Res (2023) 83 (7_Supplement): 173.

https://doi.org/10.1158/1538-7445.AM2023-173

Published: 04 April 2023

View articletitled, Abstract 173: Genomic characterization of patient-derived pancreatic cancer organoids

Journal Articles

Abstract A003: Developmental parallels in pancreatic cancer subtypes revealed by single cell transcriptomics

Sabrina Ge, Gun Ho Jang, Michelle Chan-Seng-Yue, Eugenia Flores Figueroa, Karen Ng, Stephanie Ramotar, Anna Dodd, Grainne M. O'Kane, Julie M. Wilson, Jennifer J. Knox, Sandra E. Fischer, Steven Gallinger, Faiyaz Notta

Cancer Res (2022) 82 (22_Supplement): A003.

https://doi.org/10.1158/1538-7445.PANCA22-A003

Published: 15 November 2022

View articletitled, Abstract A003: Developmental parallels in pancreatic cancer subtypes revealed by single cell transcriptomics

Journal Articles

Abstract A036: Plasma extracellular RNA for the detection of pancreatic cancer

Linsey Gong, Yuanchang Fang, Karen Ng, Gun Ho Jang, Amy X. Zhang, Julie M. Wilson, Stephanie Ramotar, Jennifer J. Knox, Grainne M. O'Kane, Steven Gallinger, Hansen H. He, Faiyaz Notta

Cancer Res (2022) 82 (22_Supplement): A036.

https://doi.org/10.1158/1538-7445.PANCA22-A036

Published: 15 November 2022

View articletitled, Abstract A036: Plasma extracellular RNA for the detection of pancreatic cancer

Journal Articles

Abstract A031: Proteogenomic analysis of the PDAC epithelium reveals tissue markers of subtype identity and biology

Cancer Res (2022) 82 (22_Supplement): A031.

https://doi.org/10.1158/1538-7445.PANCA22-A031

Published: 15 November 2022

View articletitled, Abstract A031: Proteogenomic analysis of the PDAC epithelium reveals tissue markers of subtype identity and biology

Journal Articles

Abstract A064: High-throughput organoid drug screening to identify molecular vulnerabilities in pancreatic cancer

Irene Y Xie, Zhen-Mei Liu, Karen Ng, Eugenia Flores-Figueroa, Gun Ho Jang, Amy X. Zhang, Stephanie Ramotar, Anna Dodd, Julie Wilson, Grainne M. O'Kane, Jennifer J. Knox, Steven Gallinger, Faiyaz Notta

Cancer Res (2022) 82 (22_Supplement): A064.

https://doi.org/10.1158/1538-7445.PANCA22-A064

Published: 15 November 2022

View articletitled, Abstract A064: High-throughput organoid drug screening to identify molecular vulnerabilities in pancreatic cancer

Journal Articles

Abstract LB177: Widespread hypertranscription in aggressive human cancer

Matthew Zatzman, Fabio Fuligni, Ryan Ripsman, Tannu Suwal, Lisa-Monique Edward, Rob Denroche, Gun Ho Jang, Faiyaz Notta, Steven Gallinger, Saravana P. Selvanathan, Jeffrey Toretsky, Matthew D. Hellmann, Uri Tabori, Annie Huang, Adam Shlien

Cancer Res (2022) 82 (12_Supplement): LB177.

https://doi.org/10.1158/1538-7445.AM2022-LB177

Published: 15 June 2022

View articletitled, Abstract LB177: Widespread hypertranscription in aggressive human cancer

Journal Articles

Abstract PO-077: Establishment of a novel living biobank of patient-derived pancreatic cancer organoids with genomic and drug response characterization

Irene Y. Xie, Laura Tamblyn, Karen Ng, Eugenia Flores-Figueroa, Julie M. Wilson, Gun Ho Jang, Amy X. Zhang, Stephanie Ramotar, Anna Dodd, Nikolina Radulovich, Jennifer J. Knox, Grainne M. O'Kane, Steven Gallinger, Faiyaz Notta

Cancer Res (2021) 81 (22_Supplement): PO-077.

https://doi.org/10.1158/1538-7445.PANCA21-PO-077

Published: 15 November 2021

View articletitled, Abstract PO-077: Establishment of a novel living biobank of patient-derived pancreatic cancer organoids with genomic and drug response characterization

Journal Articles

Abstract 1485: Tumors with homologous recombination repair deficiency signatures associate with an RNAseq profile profile suggestive of T cell-inflammation

Joan Miguel Romero, Alain Pacis, Rob E. Denroche, Gun Ho Jang, Barbara Grünwald, Yifan Wang, Steven Gallinger, George Zogopoulos

Cancer Res (2021) 81 (13_Supplement): 1485.

https://doi.org/10.1158/1538-7445.AM2021-1485

Published: 01 July 2021

View articletitled, Abstract 1485: Tumors with homologous recombination repair deficiency signatures associate with an RNAseq profile profile suggestive of T cell-inflammation

Journal Articles

Abstract PR-002: Stromal phenotypic heterogeneity fosters pancreatic cancer progression

Cancer Res (2020) 80 (22_Supplement): PR-002.

https://doi.org/10.1158/1538-7445.PANCA20-PR-002

Published: 13 November 2020

View articletitled, Abstract PR-002: Stromal phenotypic heterogeneity fosters pancreatic cancer progression

Journal Articles

Abstract 5465: HRDetect as a predictive score of platinum response in advanced PDAC

Cancer Res (2020) 80 (16_Supplement): 5465.

https://doi.org/10.1158/1538-7445.AM2020-5465

Published: 15 August 2020

View articletitled, Abstract 5465: HRDetect as a predictive score of platinum response in advanced PDAC

Journal Articles

Abstract A61: Tandem duplicator phenotype: A potentially targetable genomic subgroup in pancreas cancer

Amy X. Zhang, Grainne M. O'Kane, Robert E. Denroche, Gun Ho Jang, Sandra E. Fischer, Sarah Picardo, Ilinca Lungu, Anna Dodd, Julie Wilson, Yifan Wang, George Zogopoulos, Elina Elimova, Elaine Bouttell, Rebecca Prince, Raymond Jang, James J. Biagi, Faiyaz Notta, Steve Gallinger, Jennifer J. Knox

Cancer Res (2019) 79 (24_Supplement): A61.

https://doi.org/10.1158/1538-7445.PANCA19-A61

Published: 13 December 2019

View articletitled, Abstract A61: Tandem duplicator phenotype: A potentially targetable genomic subgroup in pancreas cancer

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Abstract 7161: HMGA2 predicts treatment outcome in pancreatic cancer

Abstract 3261: Plasma whole-genome sequencing to monitor pancreatic cancer

Abstract 3161: High throughput drug screening to uncover molecular vulnerabilities in pancreatic ductal adenocarcinoma

Abstract 1438: HMGA2 and protein leucine methylation drive pancreatic cancer lineage plasticity

MICAL2 Promotes Pancreatic Cancer Growth and Metastasis

Abstract A066: nSMase2-mediated exosome secretion shapes the tumor microenvironment to immunologically support pancreatic cancer

Abstract 6235: Clinical and phenotypic consequences of HLA mediated antigen presentation deficiency in pancreatic adenocarcinoma at bulk and single-cell resolution

Abstract A041: Characterizing antigen presentation associated immune escape mechanisms in pancreatic adenocarcinoma using an integrative computational approach

Abstract C059: Hub gene analysis identifies CAD as a potential mediator for drug resistance in pancreatic cancer

Abstract 173: Genomic characterization of patient-derived pancreatic cancer organoids

Abstract A003: Developmental parallels in pancreatic cancer subtypes revealed by single cell transcriptomics

Abstract A036: Plasma extracellular RNA for the detection of pancreatic cancer

Abstract A031: Proteogenomic analysis of the PDAC epithelium reveals tissue markers of subtype identity and biology

Abstract A064: High-throughput organoid drug screening to identify molecular vulnerabilities in pancreatic cancer

Abstract LB177: Widespread hypertranscription in aggressive human cancer

Abstract PO-077: Establishment of a novel living biobank of patient-derived pancreatic cancer organoids with genomic and drug response characterization

Abstract 1485: Tumors with homologous recombination repair deficiency signatures associate with an RNAseq profile profile suggestive of T cell-inflammation

Abstract PR-002: Stromal phenotypic heterogeneity fosters pancreatic cancer progression

Abstract 5465: HRDetect as a predictive score of platinum response in advanced PDAC

Abstract A61: Tandem duplicator phenotype: A potentially targetable genomic subgroup in pancreas cancer

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