Search Results | Cancer Research | American Association for Cancer Research

1-20 of 29

Sort by

Sort Order Select

Journal Articles

Abstract LB-222: Polyfunctionality determined by single-cell proteomics of bone marrow-derived CD4 T cells from patients with acute myeloid leukemia identifies patients responding to anti-PD-1-based therapy and discovers profound T cell defect in mutant TP53 disease

Naval Daver, Hagop Kantarjian, Sean Mackay, Brianna Flynn, Sreyashi Basu, Guillermo Garcia-Manero, Mansour Alfayez, Marina Konopleva, Jairo Matthews, Steven Kornblau, Ellias Jabbour, Jing Zhou, Michael Andreeff

Cancer Res (2019) 79 (13_Supplement): LB-222.

DOI: https://doi.org/10.1158/1538-7445.AM2019-LB-222

Published: 01 July 2019

View article

Journal Articles

Abstract 2725: The single-cell atlas of driver mutations in acute myeloid leukemia

Cancer Res (2019) 79 (13_Supplement): 2725.

DOI: https://doi.org/10.1158/1538-7445.AM2019-2725

Published: 01 July 2019

View article

Journal Articles

Abstract CT068: Phase Ib/II combination study of APR-246 and azacitidine (AZA) in patients with TP53 mutant myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML)

Cancer Res (2018) 78 (13_Supplement): CT068.

DOI: https://doi.org/10.1158/1538-7445.AM2018-CT068

Published: 01 July 2018

View article

Journal Articles

Abstract 2776: Genetic correlations with clinical response to ASTX727 in patients with myelodysplastic syndromes (MDS)

Haley E. Ramsey, Shilin Zhao, Yaomin Xu, Olatoyosi Otoyosi, Philip Amrein, Amy Dezern, Laura Michaelis, David P. Steensma, Stefan Faderl, Guillermo Garcia-Manero, James Lowder, Pietro Taverna, Michael R. Savona

Cancer Res (2017) 77 (13_Supplement): 2776.

DOI: https://doi.org/10.1158/1538-7445.AM2017-2776

Published: 01 July 2017

View article

Journal Articles

Abstract 3205: Defining the immune checkpoint landscape of acute myeloid leukemia (AML)

Cancer Res (2016) 76 (14_Supplement): 3205.

DOI: https://doi.org/10.1158/1538-7445.AM2016-3205

Published: 15 July 2016

View article

Journal Articles

Abstract 5033: Clonal origin of therapy-related myeloid neoplasms

Koichi Takahashi, Feng Wang, Hagop Kantarjian, Doss Denaha, Erika Thompson, Curtis Gumbs, Keyur Patel, Sattva Neelapu, Yan Wang, Zachary Bohannan, Courtney DiNardo, Farhad Ravandi, Zeev Estrov, Simona Colla, Jianhua Zhang, Xifeng Wu, Guillermo Garcia-Manero, Andrew Futreal

Cancer Res (2016) 76 (14_Supplement): 5033.

DOI: https://doi.org/10.1158/1538-7445.AM2016-5033

Published: 15 July 2016

View article

Journal Articles

Abstract CT307: Phase I/II study of vosaroxin and decitabine in older patients (pts) with acute myeloid leukemia (AML) and high risk myelodysplastic syndrome (MDS)

Naval Daver, Hagop M. Kantarjian, Guillermo Garcia - Manero, Naveen Pemmaraju, Tapan Kadia, Courtney DiNardo, Nitin Jain, Gautum Borthakur, Jorge Cortes, Craig Adam, Farhad Ravandi

Cancer Res (2014) 74 (19_Supplement): CT307.

DOI: https://doi.org/10.1158/1538-7445.AM2014-CT307

Published: 01 October 2014

View article

Journal Articles

Abstract 592: Preclinical evaluation of the PARP inhibitor veliparib (ABT-888) in combination with cytotoxic chemotherapy in acute myeloid leukemia.

Tapan Kadia, Sara McCay, Hui Yang, Irene Ganan-Gomez, Yue Wei, Guillermo Garcia-Manero

Cancer Res (2013) 73 (8_Supplement): 592.

DOI: https://doi.org/10.1158/1538-7445.AM2013-592

Published: 15 April 2013

View article

Journal Articles

Abstract 4800: Genome-wide CHIP-Seq analysis of histone methylation reveals modulators of NF-κB signaling and the histone demethylase JMJD3 as implicated in disease progression in myelodysplastic syndrome (MDS)

Yue Wei, Rui Chen, Carlos Bueso-Ramos, Hui Yang, Guillermo Garcia-Manero

Cancer Res (2010) 70 (8_Supplement): 4800.

DOI: https://doi.org/10.1158/1538-7445.AM10-4800

Published: 15 April 2010

View article

Journal Articles

Induction of an anti-angiogenesis factor, Thrombospondin 1 (TSP-1), by a novel histone deacetylase inhibitor, MGCD0103, in human cancer cells in vitro and in vivo

Jianhong Liu, Claire Bonfils, Marja Dubay, Hannah Nguyen, Guillermo Garcia-Manero, Allen Yang, Selina Luger, Robert Martell, Jeffrey Besterman, Zuomei Li

Cancer Res (2008) 68 (9_Supplement): 739.

Published: 01 May 2008

View article

Journal Articles

Identification of novel differentially methylated markers in adult acute lymphocytic leukemias

Shao-Qing Kuang, Hui Yang, Jaroslav Jelinek, Weigang Tong, Jean-Pierre Issa, Guillermo Garcia-Manero

Cancer Res (2007) 67 (9_Supplement): 1131.

Published: 01 May 2007

View article

Journal Articles

Global gene methylation profiling of CLL patients and its implication in therapy

Wei-gang Tong, Shang-Qing Kuang, William Wierda, Guillermo Garcia-Manero

Cancer Res (2007) 67 (9_Supplement): 1112.

Published: 01 May 2007

View article

Journal Articles

The dual ABL/SRC inhibitors dasatinib, SKI-606, and INNO-406 are potent inhibitors of T cell acute lymphoblastic leukemia cell lines expressing the NUP214-ABL1 fusion kinase

Alfonso Quintas-Cardama, Taghi Manshouri, Weigang Tong, Hagop Kantarjian, Jorge Cortes, Guillermo Garcia-Manero

Cancer Res (2007) 67 (9_Supplement): 1825.

Published: 01 May 2007

View article

Journal Articles

RIL, a LIM Gene on 5q31, Is Silenced by Methylation in Cancer and Sensitizes Cancer Cells to Apoptosis

Yanis A. Boumber, Yutaka Kondo, Xuqi Chen, Lanlan Shen, Vazganush Gharibyan, Kazuo Konishi, Elihu Estey, Hagop Kantarjian, Guillermo Garcia-Manero, Jean-Pierre J. Issa

Cancer Res (2007) 67 (5): 1997–2005.

DOI: https://doi.org/10.1158/0008-5472.CAN-06-3093

Published: 01 March 2007

View article

Includes: Supplementary data

Journal Articles

DNA Methylation Changes after 5-Aza-2′-Deoxycytidine Therapy in Patients with Leukemia

Allen S. Yang, Ketan D. Doshi, Sang-Woon Choi, Joel B. Mason, Rajan K. Mannari, Vazganush Gharybian, Rene Luna, Asif Rashid, Lanlan Shen, Marcos R.H. Estecio, Hagop M. Kantarjian, Guillermo Garcia-Manero, Jean-Pierre J. Issa

Cancer Res (2006) 66 (10): 5495–5503.

DOI: https://doi.org/10.1158/0008-5472.CAN-05-2385

Published: 16 May 2006

View article

Includes: Supplementary data

Journal Articles

Expression analysis of the p15^INK4B and p21^Cip/WAF genes in patients with MDS treated with decitabine

Yasuhiro Oki, Hagop M. Kantarjian, Jan Davis, Farhad Ravandi, Srdan Verstovsek, Jorge E. Cortes, Guillermo Garcia-Manero, Jean-Pierre Issa

Cancer Res (2006) 66 (8_Supplement): 540.

Published: 15 April 2006

View article

Journal Articles

Switch from a one-allele to two-allele mutation of the deoxycytidine kinase gene causes resistance to 5-aza-2’-deoxycytidine in the HL 60 cell line

Taichun Qin, Sr, Jaroslav Jelinek, Sr, Emile Youssef, Sr, Guillermo Garcia-Manero, Sr, Jean-Pierre Issa, Sr

Cancer Res (2006) 66 (8_Supplement): 382.

Published: 15 April 2006

View article

Journal Articles

Global genomic DNA methylation pattern and combination effects of 1-beta-D-arabinofuranosylcytosine and 5-aza-2’-deoxycytidine in human leukemic cells

Taichun Qin, Emile M. Youssef, Allen Yang, Guillermo Garcia-Manero, Jean-Pierre J. Issa

Cancer Res (2005) 65 (9_Supplement): 425–426.

Published: 01 May 2005

View article

Journal Articles

Cloretazine™, a novel sulfonylhydrazine alkylating agent, combined with cytarabine is an active regimen in patients with refractory hematologic malignancies

Francis J. Giles, Susan O’Brien, Srdan Verstovsek, Jorge Cortes, Debra Thomas, Stephan Faderl, Alessandra Ferrajoli, Farhad Ravandi-Kashani, Steven Kornblau, Guillermo Garcia-Manero, Ann Cahill, Mario Sznol, Hagop Kantarjian

Cancer Res (2005) 65 (9_Supplement): 935.

Published: 01 May 2005

View article

Journal Articles

In vivo molecular implications of the combination of the hypo-methylating agent 5-aza-2’-deoxycytidine and the histone deacetylase inhibitor valproic acid in patients with leukemia: Results of a phase I/II study

Blanca Sanchez-Gonzalez, Hui Yang, Marta Cuadros, Claritza Santos-Malave, Koyu Hoshino, Hagop Kantarjian, Jean-Pierre Issa, Guillermo Garcia-Manero

Cancer Res (2005) 65 (9_Supplement): 937.

Published: 01 May 2005

View article

NARROW

Abstract LB-222: Polyfunctionality determined by single-cell proteomics of bone marrow-derived CD4 T cells from patients with acute myeloid leukemia identifies patients responding to anti-PD-1-based therapy and discovers profound T cell defect in mutant TP53 disease

Abstract 2725: The single-cell atlas of driver mutations in acute myeloid leukemia

Abstract CT068: Phase Ib/II combination study of APR-246 and azacitidine (AZA) in patients with TP53 mutant myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML)

Abstract 2776: Genetic correlations with clinical response to ASTX727 in patients with myelodysplastic syndromes (MDS)

Abstract 3205: Defining the immune checkpoint landscape of acute myeloid leukemia (AML)

Abstract 5033: Clonal origin of therapy-related myeloid neoplasms

Abstract CT307: Phase I/II study of vosaroxin and decitabine in older patients (pts) with acute myeloid leukemia (AML) and high risk myelodysplastic syndrome (MDS)

Abstract 592: Preclinical evaluation of the PARP inhibitor veliparib (ABT-888) in combination with cytotoxic chemotherapy in acute myeloid leukemia.

Abstract 4800: Genome-wide CHIP-Seq analysis of histone methylation reveals modulators of NF-κB signaling and the histone demethylase JMJD3 as implicated in disease progression in myelodysplastic syndrome (MDS)

Induction of an anti-angiogenesis factor, Thrombospondin 1 (TSP-1), by a novel histone deacetylase inhibitor, MGCD0103, in human cancer cells in vitro and in vivo

Identification of novel differentially methylated markers in adult acute lymphocytic leukemias

Global gene methylation profiling of CLL patients and its implication in therapy

The dual ABL/SRC inhibitors dasatinib, SKI-606, and INNO-406 are potent inhibitors of T cell acute lymphoblastic leukemia cell lines expressing the NUP214-ABL1 fusion kinase

RIL, a LIM Gene on 5q31, Is Silenced by Methylation in Cancer and Sensitizes Cancer Cells to Apoptosis

DNA Methylation Changes after 5-Aza-2′-Deoxycytidine Therapy in Patients with Leukemia

Expression analysis of the p15^INK4B and p21^Cip/WAF genes in patients with MDS treated with decitabine

Switch from a one-allele to two-allele mutation of the deoxycytidine kinase gene causes resistance to 5-aza-2’-deoxycytidine in the HL 60 cell line

Global genomic DNA methylation pattern and combination effects of 1-beta-D-arabinofuranosylcytosine and 5-aza-2’-deoxycytidine in human leukemic cells

Cloretazine™, a novel sulfonylhydrazine alkylating agent, combined with cytarabine is an active regimen in patients with refractory hematologic malignancies

In vivo molecular implications of the combination of the hypo-methylating agent 5-aza-2’-deoxycytidine and the histone deacetylase inhibitor valproic acid in patients with leukemia: Results of a phase I/II study

Email alerts

AACR Journals

Email alerts

AACR Journals

This Feature Is Available To Subscribers Only