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Gregory J. Riely
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Journal Articles

Analysis and Visualization of Longitudinal Genomic and Clinical Data from the AACR Project GENIE Biopharma Collaborative in cBioPortal

Ino de Bruijn, Ritika Kundra, Brooke Mastrogiacomo, Thinh Ngoc Tran, Luke Sikina, Tali Mazor, Xiang Li, Angelica Ochoa, Gaofei Zhao, Bryan Lai, Adam Abeshouse, Diana Baiceanu, Ersin Ciftci, Ugur Dogrusoz, Andrew Dufilie, Ziya Erkoc, Elena Garcia Lara, Zhaoyuan Fu, Benjamin Gross, Charles Haynes, Allison Heath, David Higgins, Prasanna Jagannathan, Karthik Kalletla, Priti Kumari, James Lindsay, Aaron Lisman, Bas Leenknegt, Pieter Lukasse, Divya Madela, Ramyasree Madupuri, Pim van Nierop, Oleguer Plantalech, Joyce Quach, Adam C. Resnick, Sander Y.A. Rodenburg, Baby A. Satravada, Fedde Schaeffer, Robert Sheridan, Jessica Singh, Rajat Sirohi, Selcuk Onur Sumer, Sjoerd van Hagen, Avery Wang, Manda Wilson, Hongxin Zhang, Kelsey Zhu, Nicole Rusk, Samantha Brown, Jessica A. Lavery, Katherine S. Panageas, Julia E. Rudolph, Michele L. LeNoue-Newton, Jeremy L. Warner, Xindi Guo, Haley Hunter-Zinck, Thomas V. Yu, Shirin Pilai, Chelsea Nichols, Stuart M. Gardos, John Philip, AACR Project GENIE BPC Core Team, AACR Project GENIE Consortium, Kenneth L. Kehl, Gregory J. Riely, Deborah Schrag, Jocelyn Lee, Michael V. Fiandalo, Shawn M. Sweeney, Trevor J. Pugh, Chris Sander, Ethan Cerami, Jianjiong Gao, Nikolaus Schultz
Journal: Cancer Research
Cancer Res (2023) 83 (23): 3861–3867.
https://doi.org/10.1158/0008-5472.CAN-23-0816
Published: 01 December 2023
View article titled, Analysis and Visualization of Longitudinal Genomic and Clinical Data from the AACR Project GENIE Biopharma Collaborative in cBioPortal
Open the PDF for Analysis and Visualization of Longitudinal Genomic and Clinical Data from the AACR Project GENIE Biopharma Collaborative in cBioPortal in another window
Includes: Supplementary data
Journal Articles

Abstract 5185: Intratumoral Escherichia is associated with response to single-agent immune checkpoint inhibition in patients with advanced non-small cell lung cancer

Arielle Elkrief, Anita S. Bowman, Ayyuce Begum Bektas, Wenfei Kang, Katia Manova-Todorova, Jacklynn V. Egger, Hira Rizvi, Daniel Kelly, Eric Chan, Eric Rosiek, Fan Ning, Gregory J. Riely, Álvaro Quintanal Villalonga, Snjezana Dogan, Umesh Bhanot, Mithat Gonen, Matthew D. Hellmann, Adam J. Schoenfeld, Charles M. Rudin, Marc Ladanyi, Chad M. Vanderbilt
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5185.
https://doi.org/10.1158/1538-7445.AM2023-5185
Published: 04 April 2023
View article titled, Abstract 5185: Intratumoral <em>Escherichia</em> is associated with response to single-agent immune checkpoint inhibition in patients with advanced non-small cell lung cancer
Journal Articles

Abstract 1177: Genomic characteristics and clinical outcomes of early onset colorectal cancer (EOCRC): Findings from AACR Project GENIE Biopharma Collaborative registry

Enrique Sanz Garcia, Eric Chen, Marios Giannakis, Gregory J. Riely, Jeremy L. Warner, Michele L. LeNoue-Newton, Jessica Weiss, Katrina Hueniken, Kenneth L. Kehl, Deborah Schrag, Andrea Cercek, Kimmie Ng, AACR GENIE BPC Core Team
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1177.
https://doi.org/10.1158/1538-7445.AM2023-1177
Published: 04 April 2023
View article titled, Abstract 1177: Genomic characteristics and clinical outcomes of early onset colorectal cancer (EOCRC): Findings from AACR Project GENIE Biopharma Collaborative registry
Journal Articles

Abstract 5721: Automated annotation for large-scale clinicogenomic models of lung cancer treatment response and overall survival

Justin Jee, Chris Fong, Karl Pichotta, Thinh Tran, Anisha Luthra, Mirella Altoe, Steven Maron, Ronglai Shen, Si-Yang Liu, Michele Waters, Joseph Kholodenko, Brooke Mastrogiacomo, Susie Kim, A Rose Brannon, Michael F. Berger, Axel Martin, Jason Chang, Anton Safonov, Jorge S. Reis-Filho, Deborah Schrag, Sohrab P. Shah, Pedram Razavi, Bob T. Li, Gregory J. Riely, Nikolaus Schultz
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5721.
https://doi.org/10.1158/1538-7445.AM2023-5721
Published: 04 April 2023
View article titled, Abstract 5721: Automated annotation for large-scale clinicogenomic models of lung cancer treatment response and overall survival
Journal Articles

Abstract 6127: MDM2 inhibition in combination with MEK inhibition in pre-clinical models of lung adenocarcinomas with MDM2 amplification

Arielle Elkrief, Vladimir Markov, Álvaro Quintanal-Villalonga, Rebecca Caeser, Pawel Sobczuk, Emily Cheng, Alexander Drilon, Gregory J. Riely, William W. Lockwood, Elisa de Stanchina, Charles M. Rudin, Igor Odintsov, Romel Somwar
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6127.
https://doi.org/10.1158/1538-7445.AM2023-6127
Published: 04 April 2023
View article titled, Abstract 6127: MDM2 inhibition in combination with MEK inhibition in pre-clinical models of lung adenocarcinomas with <em>MDM2</em> amplification
Journal Articles

Abstract 4259: Identification of anti-neoplastic therapy given before initial visit at a referral center using natural language processing applied to medical oncology initial consultation notes

Thinh N. Tran, Karl B. Pichotta, Si-Yang Liu, Christopher Fong, Anisha Luthra, Brooke Mastrogiacomo, Steven Maron, Deborah Schrag, Sohrab P. Shah, Pedram Razavi, Bob T. Li, Gregory J. Riely, Nikolaus Schultz, Justin Jee
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4259.
https://doi.org/10.1158/1538-7445.AM2023-4259
Published: 04 April 2023
View article titled, Abstract 4259: Identification of anti-neoplastic therapy given before initial visit at a referral center using natural language processing applied to medical oncology initial consultation notes
Journal Articles

Abstract 4260: Understanding genomic and social determinants of cancer immunotherapy outcome across ancestry

Christopher J. Fong, Michele Waters, Karl Pichotta, Justin Jee, Devika R. Jutagir, David Ma, Tomin Perea-Chamblee, Susie Kim, Kanika Arora, Brooke Mastrogiacomo, Thinh Tran, Steven Maron, Mirella Altoe, Anisha Luthra, Joseph Kholodenko, Arfath Patha, Doori Rose, Michael F. Berger, Gregory J. Riely, Nikolaus Schultz, Sanna Goyert, Adam Schoenfeld, Francesca Gany, Jian Carrot-Zhang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4260.
https://doi.org/10.1158/1538-7445.AM2023-4260
Published: 04 April 2023
View article titled, Abstract 4260: Understanding genomic and social determinants of cancer immunotherapy outcome across ancestry
Journal Articles

Genomic Landscapes and Hallmarks of Mutant RAS in Human Cancers

Robert B. Scharpf, Archana Balan, Biagio Ricciuti, Jacob Fiksel, Christopher Cherry, Chenguang Wang, Michele L. Lenoue-Newton, Hira A. Rizvi, James R. White, Alexander S. Baras, Jordan Anaya, Blair V. Landon, Marta Majcherska-Agrawal, Paola Ghanem, Jocelyn Lee, Leon Raskin, Andrew S. Park, Huakang Tu, Hil Hsu, Kathryn C. Arbour, Mark M. Awad, Gregory J. Riely, Christine M. Lovly, Valsamo Anagnostou
Journal: Cancer Research
Cancer Res (2022) 82 (21): 4058–4078.
https://doi.org/10.1158/0008-5472.CAN-22-1731
Published: 02 November 2022
View article titled, Genomic Landscapes and Hallmarks of Mutant RAS in Human Cancers
Open the PDF for Genomic Landscapes and Hallmarks of Mutant RAS in Human Cancers in another window
Includes: Supplementary data
Journal Articles

Abstract 1111: MYC promotes tyrosine kinase inhibitor resistance in ROS1 fusion positive lung cancers

Sudarshan R. Iyer, Igor Odintsov, Adam J. Schoenfeld, Hiroki Sato, Evan Siau, Alexander Drilon, Gregory J. Riely, Romel Somwar, Marc Ladanyi, Monika A. Davare
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1111.
https://doi.org/10.1158/1538-7445.AM2021-1111
Published: 01 July 2021
View article titled, Abstract 1111: MYC promotes tyrosine kinase inhibitor resistance in <em>ROS1</em> fusion positive lung cancers
Journal Articles

Abstract 2619: Defining real-world recurrence in the AACR Project GENIE Biopharma Collaborative Data

Jessica A. Lavery, Samantha Brown, Eva Lepisto, Michele L. Lenoue-Newton, Caroline McCarthy, Hira Rizvi, Celeste Yu, Kenneth L. Kehl, Shawn M. Sweeney, Julia E. Rudolph, Nikolaus Schultz, Brooke Mastrogiacomo, Ritika Kundra, Jeremy Warner, Philippe Bedard, Gregory J. Riely, Katherine S. Panageas, Deborah Schrag, AACR Project GENIE Consortium
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2619.
https://doi.org/10.1158/1538-7445.AM2021-2619
Published: 01 July 2021
View article titled, Abstract 2619: Defining real-world recurrence in the AACR Project GENIE Biopharma Collaborative Data
Journal Articles

Abstract 2620: Ignoring left truncation in overall survival within real-world genomic-phenomic data leads to inflated survival estimates

Samantha Brown, Jessica A. Lavery, Eva M. Lepisto, Caroline McCarthy, Hira Rizvi, Celeste Yu, Kenneth L. Kehl, Shawn M. Sweeney, Julia E. Rudolph, Nikolaus Schultz, Ritika Kundra, Brooke Mastrogiacomo, Phillipe Bedard, Jeremy L. Warner, Gregory J. Riely, Deborah Schrag, Katherine S. Panageas, The AACR Project GENIE Consortium
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2620.
https://doi.org/10.1158/1538-7445.AM2021-2620
Published: 01 July 2021
View article titled, Abstract 2620: Ignoring left truncation in overall survival within real-world genomic-phenomic data leads to inflated survival estimates
Journal Articles

Abstract 2506: Smarca4 inactivation promotes lineage-specific transformation and early metastatic features in the lung

Carla P. Concepcion, Sai Ma, Lindsay M. LaFave, Arjun Bhutkar, Manyuan Liu, Lydia P. DeAngelo, Jonathan Y. Kim, Isabella Del Priore, Adam J. Schoenfeld, Vinay K. Kartha, Peter M. Westcott, Francisco J. Sánchez-Rivera, Kevin Meli, Manav Gupta, Gregory J. Riely, Natasha Rekhtman, Charles M. Rudin, Carla F. Kim, Aviv Regev, Jason D. Buenrostro, Tyler Jacks
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2506.
https://doi.org/10.1158/1538-7445.AM2021-2506
Published: 01 July 2021
View article titled, Abstract 2506: <em>Smarca4</em> inactivation promotes lineage-specific transformation and early metastatic features in the lung
Journal Articles

Abstract 709: The utility of plasma ctDNA for detection of KRAS G12C and other mutations in lung cancers

Yonina R. Murciano-Goroff, Kathryn C. Arbour, Michael D. Offin, Hai-Yan Y. Tu, Emily S. Lebow, Tristan S. Shaffer, Caterina Bertucci, Syed A. Hosseini, Kavita Garg, Lee P. Lim, Mark Li, Jason C. Chang, Jorge S. Reis-Filho, Pedram Razavi, James M. Isbell, Gregory J. Riely, David M. Hyman, Piro Lito, Bob T. Li
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 709.
https://doi.org/10.1158/1538-7445.AM2020-709
Published: 15 August 2020
View article titled, Abstract 709: The utility of plasma ctDNA for detection of <em>KRAS</em> G12C and other mutations in lung cancers
Journal Articles

Abstract CT025: Impact of the EML4-ALK fusion variant on the efficacy of lorlatinib in patients (pts) with ALK-positive advanced non-small cell lung cancer (NSCLC)

Todd M. Bauer, Jean-François Martini, Benjamin Besse, Chia-Chi Lin, Ross A. Soo, Gregory J. Riely, Sai-Hong Ignatius Ou, Francesca Toffalorio, Antonello Abbattista, Holger Thurm, D. Ross Camidge, Steven Kao, Rita Chiari, Shirish Gadgeel, Enriqueta Felip, Alice T. Shaw, Benjamin J. Solomon
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): CT025.
https://doi.org/10.1158/1538-7445.AM2020-CT025
Published: 15 August 2020
View article titled, Abstract CT025: Impact of the EML4-ALK fusion variant on the efficacy of lorlatinib in patients (pts) with ALK-positive advanced non-small cell lung cancer (NSCLC)
Journal Articles

Abstract CT044: Efficacy of lorlatinib in patients (pts) with advanced ALK-positive non-small cell lung cancer (NSCLC) and ALK kinase domain mutations

Alice T. Shaw, Jean-François Martini, Benjamin Besse, Todd M. Bauer, Chia-Chi Lin, Ross A. Soo, Gregory J. Riely, Sai-Hong Ignatius Ou, Jill S. Clancy, Sherry Li, Holger Thurm, Miyako Satouchi, D. Ross Camidge, Steven Kao, Rita Chiari, Shirish Gadgeel, Enriqueta Felip, Benjamin J. Solomon
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): CT044.
https://doi.org/10.1158/1538-7445.AM2018-CT044
Published: 01 July 2018
View article titled, Abstract CT044: Efficacy of lorlatinib in patients (pts) with advanced ALK-positive non-small cell lung cancer (NSCLC) and <em>ALK</em> kinase domain mutations
Journal Articles

Abstract 4342: Ultra-deep next generation sequencing (NGS) of plasma cell-free DNA (cfDNA) from patients with advanced lung cancers: results from the Actionable Genome Consortium

Bob T. Li, Filip Janku, Pasi A. Janne, Gordon B. Mills, Kiran Madwani, Ryan S. Alden, Cloud P. Paweletz, Marc Ladanyi, Alex Aravanis, Byoungsok Jung, Sante Gnerre, Amy J. Sehnert, David B. Solit, Gregory J. Riely, Geoffrey R. Oxnard
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4342.
https://doi.org/10.1158/1538-7445.AM2016-4342
Published: 15 July 2016
View article titled, Abstract 4342: Ultra-deep next generation sequencing (NGS) of plasma cell-free DNA (cfDNA) from patients with advanced lung cancers: results from the Actionable Genome Consortium
Journal Articles

Abstract 610: Prospective genomic characterization of small cell lung cancer by targeted next generation sequencing

Helen H. Won, M. Catherine Pietanza, Lee M. Krug, Anna M. Varghese, Natasha Rekhtman, Lu Wang, William Travis, Paul K. Paik, Gregory J. Riely, Maureen F. Zakowski, Marc Ladanyi, Mark G. Kris, Charles M. Rudin, Michael F. Berger
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 610.
https://doi.org/10.1158/1538-7445.AM2015-610
Published: 01 August 2015
View article titled, Abstract 610: Prospective genomic characterization of small cell lung cancer by targeted next generation sequencing
Journal Articles

Abstract 1784: Erlotinib at a dose of 25 mg daily for non-small cell lung cancers with EGFR mutations

Wee-Lee Yeo, Gregory J. Riely, Mark G. Kris, Daniel G. Tenen, William Pao, Susumu Kobayashi, Daniel B. Costa
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1784.
https://doi.org/10.1158/1538-7445.AM10-1784
Published: 15 April 2010
View article titled, Abstract 1784: Erlotinib at a dose of 25 mg daily for non-small cell lung cancers with <em>EGFR</em> mutations
Journal Articles

Acquired resistance to EGFR tyrosine kinase inhibitors in lung cancer.

Marissa N. Balak, Gregory J. Riely, Allan R. Li, Maureen F. Zakowski, Marc Ladanyi, Vincent A. Miller, William Pao
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1360.
Published: 15 April 2006
View article titled, Acquired resistance to EGFR tyrosine kinase inhibitors in lung cancer.