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Journal Articles

Abstract 4438: Promoter hypermethylation status of Fanconi Anemia (FA) pathway genes FANCF, FANCL and FANCS in non-small cell lung cancer (NSCLC)

Andrew Fink, Arjun Kalvala, Li Gao, Kathleen Dotts, Brittany Aguila, Shirley Tang, Gregory A. Otterson, Miguel A. Villalona-Calero, Wenrui Duan

Cancer Res (2016) 76 (14_Supplement): 4438.

https://doi.org/10.1158/1538-7445.AM2016-4438

Published: 15 July 2016

View article titled, Abstract 4438: Promoter hypermethylation status of Fanconi Anemia (FA) pathway genes FANCF, FANCL and FANCS in non-small cell lung cancer (NSCLC)

Journal Articles

Abstract 559: Inhibition of pro-survival pathways in lung cancer cells with functional defects in the Fanconi Anemia pathway

Li Gao, Wenrui Duan, Kathleen Dotts, Arjun Kalvala, Brittany Aguila, Gregory A. Otterson, Miguel A. Villalona-Calero

Cancer Res (2015) 75 (15_Supplement): 559.

https://doi.org/10.1158/1538-7445.AM2015-559

Published: 01 August 2015

View article titled, Abstract 559: Inhibition of pro-survival pathways in lung cancer cells with functional defects in the Fanconi Anemia pathway

Journal Articles

Abstract 5434: Combined BCL-2/XL and mTor inhibition promotes apoptosis in small cell lung cancer

Li Gao, Brittany Barnwell, Arjun Kalvala, Gregory A. Otterson, Wenrui Duan, Miguel A. Villalona-Calero

Cancer Res (2014) 74 (19_Supplement): 5434.

https://doi.org/10.1158/1538-7445.AM2014-5434

Published: 01 October 2014

View article titled, Abstract 5434: Combined BCL-2/XL and mTor inhibition promotes apoptosis in small cell lung cancer

Journal Articles

Abstract 4365: Sensitivity of small cell lung cancer cells with defective Fanconi Anemia (FA) pathway to BCL2 inhibitors..

Li Gao, Wenrui Duan, Brittany Barnwell, Arjun Kalvala, Gregory A. Otterson, Miguel A. Villalona-Calero

Cancer Res (2013) 73 (8_Supplement): 4365.

https://doi.org/10.1158/1538-7445.AM2013-4365

Published: 15 April 2013

View article titled, Abstract 4365: Sensitivity of small cell lung cancer cells with defective Fanconi Anemia (FA) pathway to BCL2 inhibitors..

Journal Articles

Abstract 4246: Promoter hypermethylation and gene expression of FANCF in non-small cell lung cancer (NSCLC).

Wenrui Duan, Tyler Rees, Kevin Vu, Brittany Barnwell, Li Gao, Arjun Kalvala, xin wu, Gregory A. Otterson, Miguel A. Villalona-Calero

Cancer Res (2013) 73 (8_Supplement): 4246.

https://doi.org/10.1158/1538-7445.AM2013-4246

Published: 15 April 2013

View article titled, Abstract 4246: Promoter hypermethylation and gene expression of FANCF in non-small cell lung cancer (NSCLC).

Journal Articles

Abstract 4082: Global miRNA expression changes induced by HDAC-42 and 5-azaCdr in lung cancer cells

Xin Wu, Fengting Yan, Wenrui Duan, Jianying Zhang, Li Gao, Melissa Crawford, Miguel A. Villalona, S. Patrick Nana-Sinkam, Gregory A. Otterson

Cancer Res (2012) 72 (8_Supplement): 4082.

https://doi.org/10.1158/1538-7445.AM2012-4082

Published: 15 April 2012

View article titled, Abstract 4082: Global miRNA expression changes induced by HDAC-42 and 5-azaCdr in lung cancer cells

Journal Articles

Abstract 4740: Establishment of P53 mutant type specific spontaneous lung tumor in transgenic mice for treatment

Wenrui Duan, Li Gao, Christopher Brooks, Arjun Kalvala, xin wu, Gregory A. Otterson, Miguel A. Villalona-Calero

Cancer Res (2012) 72 (8_Supplement): 4740.

https://doi.org/10.1158/1538-7445.AM2012-4740

Published: 15 April 2012

View article titled, Abstract 4740: Establishment of P53 mutant type specific spontaneous lung tumor in transgenic mice for treatment

Journal Articles

Abstract 4682: Compensatory activation of alternative DNA repair pathways following exposure to the PARP Inhibitor ABT-888 in vitro and in patients with solid malignancies

Li Gao, Wenrui Duan, Xin Wu, Alice Chen, Gregory A. Otterson, Miguel A. Villalona

Cancer Res (2012) 72 (8_Supplement): 4682.

https://doi.org/10.1158/1538-7445.AM2012-4682

Published: 15 April 2012

View article titled, Abstract 4682: Compensatory activation of alternative DNA repair pathways following exposure to the PARP Inhibitor ABT-888 in vitro and in patients with solid malignancies

Journal Articles

Abstract LB-225: Phase 2 Trial of nab-paclitaxel plus carboplatin for advanced NSCLC in patients at risk of bleeding from VEGF directed therapies

Erin M. Bertino, Miguel A. Villalona-Calero, Patrick Nana-Sinkam, Sarah Cantrel, Meliha Rahmani, Carrie Symmes, Gary S. Phillips, Gregory A. Otterson

Cancer Res (2012) 72 (8_Supplement): LB-225.

https://doi.org/10.1158/1538-7445.AM2012-LB-225

Published: 15 April 2012

View article titled, Abstract LB-225: Phase 2 Trial of nab-paclitaxel plus carboplatin for advanced NSCLC in patients at risk of bleeding from VEGF directed therapies

Journal Articles

Abstract 5500: Inhibition of poly(ADP-ribose) polymerase in lung cancer cells with defective Fanconi anemia (FA) pathway

Li Gao, Wenrui Duan, Xin Wu, Gregory A. Otterson, Miguel A. Villalona-Calero

Cancer Res (2011) 71 (8_Supplement): 5500.

https://doi.org/10.1158/1538-7445.AM2011-5500

Published: 15 April 2011

View article titled, Abstract 5500: Inhibition of poly(ADP-ribose) polymerase in lung cancer cells with defective Fanconi anemia (FA) pathway

Journal Articles

Abstract 610: Regression of spontaneous non-small cell lung cancers in P53 mutant transgenic mice following exposure to PRIMA-1

Wenrui Duan, Li Gao, Gregory Vereb, Xin Wu, Gregory A. Otterson, Miguel A. Villalona-Calero

Cancer Res (2011) 71 (8_Supplement): 610.

https://doi.org/10.1158/1538-7445.AM2011-610

Published: 15 April 2011

View article titled, Abstract 610: Regression of spontaneous non-small cell lung cancers in P53 mutant transgenic mice following exposure to PRIMA-1

Journal Articles

Abstract 3750: Functional analysis of the Fanconi Anemia pathway in primary lung tumors

Wenrui Duan, Li Gao, Xin Wu, Weiqiang Zhao, Marino Leon, Gregory A. Otterson, Miguel A. Villalona-Calero

Cancer Res (2010) 70 (8_Supplement): 3750.

https://doi.org/10.1158/1538-7445.AM10-3750

Published: 15 April 2010

View article titled, Abstract 3750: Functional analysis of the Fanconi Anemia pathway in primary lung tumors

Journal Articles

Establishment and characterization of a line of transgenic mice harboring a lung specific human type II p53(175H) mutation

Li Gao, Wenrui Duan, Yang Zhang, Xin Wu, Gregory A. Otterson, Miguel A. Villalona-Calero

Cancer Res (2005) 65 (9_Supplement): 245–246.

Published: 01 May 2005

View article titled, Establishment and characterization of a line of transgenic mice harboring a lung specific human type II p53(175H) mutation

Journal Articles

Differences between the Pirh2 and Mdm2 in response to DNA damage

Wenrui Duan, Li Gao, Xin Wu, Yang Zhang, Gregory A. Otterson, Miguel A. Villalona-Calero

Cancer Res (2005) 65 (9_Supplement): 858.

Published: 01 May 2005

View article titled, Differences between the Pirh2 and Mdm2 in response to DNA damage

Journal Articles

Gene dosage and aging in lung tumorigenesis in p53 (273H) transgenic mice

Li Gao, Wenrui Duan, Wei-Guo Zhu, Gregory A. Otterson, Miguel A. Villalona-Calero

Cancer Res (2004) 64 (7_Supplement): 590.

Published: 01 April 2004

View article titled, Gene dosage and aging in lung tumorigenesis in p53 (273H) transgenic mice

Journal Articles

Valproic acts as an HDAC inhibitor in cells and works synergistically with the DNMT inhibitor, 5-aza-2′-deoxycytidine

Gregory A. Otterson, Theresa Hileman, Wenrui Duan, Wei-Guo Zhu, Miguel A. Villalona-Calero

Cancer Res (2004) 64 (7_Supplement): 368.

Published: 01 April 2004

View article titled, Valproic acts as an HDAC inhibitor in cells and works synergistically with the DNMT inhibitor, 5-aza-2′-deoxycytidine

Journal Articles

Over expression of Pirh2 and concomitant reduction of p53 are associated with lung adenocarcinoma

Wenrui Duan, Li Gao, Lawrence J. Druhan, Wei-Guo Zhu, Gregory A. Otterson, Miguel A. Villalona-Calero

Cancer Res (2004) 64 (7_Supplement): 429–430.

Published: 01 April 2004

View article titled, Over expression of Pirh2 and concomitant reduction of p53 are associated with lung adenocarcinoma

Journal Articles

DNA Methyltransferase Inhibition Enhances Apoptosis Induced by Histone Deacetylase Inhibitors

Wei-Guo Zhu, Romola R. Lakshmanan, Matthew D. Beal, Gregory A. Otterson

Cancer Res (2001) 61 (4): 1327–1333.

Published: 02 February 2001

View article titled, DNA Methyltransferase Inhibition Enhances Apoptosis Induced by Histone Deacetylase Inhibitors

NARROW

Abstract 4438: Promoter hypermethylation status of Fanconi Anemia (FA) pathway genes FANCF, FANCL and FANCS in non-small cell lung cancer (NSCLC)

Abstract 559: Inhibition of pro-survival pathways in lung cancer cells with functional defects in the Fanconi Anemia pathway

Abstract 5434: Combined BCL-2/XL and mTor inhibition promotes apoptosis in small cell lung cancer

Abstract 4365: Sensitivity of small cell lung cancer cells with defective Fanconi Anemia (FA) pathway to BCL2 inhibitors..

Abstract 4246: Promoter hypermethylation and gene expression of FANCF in non-small cell lung cancer (NSCLC).

Abstract 4082: Global miRNA expression changes induced by HDAC-42 and 5-azaCdr in lung cancer cells

Abstract 4740: Establishment of P53 mutant type specific spontaneous lung tumor in transgenic mice for treatment

Abstract 4682: Compensatory activation of alternative DNA repair pathways following exposure to the PARP Inhibitor ABT-888 in vitro and in patients with solid malignancies

Abstract LB-225: Phase 2 Trial of nab-paclitaxel plus carboplatin for advanced NSCLC in patients at risk of bleeding from VEGF directed therapies

Abstract 5500: Inhibition of poly(ADP-ribose) polymerase in lung cancer cells with defective Fanconi anemia (FA) pathway

Abstract 610: Regression of spontaneous non-small cell lung cancers in P53 mutant transgenic mice following exposure to PRIMA-1

Abstract 3750: Functional analysis of the Fanconi Anemia pathway in primary lung tumors

Establishment and characterization of a line of transgenic mice harboring a lung specific human type II p53(175H) mutation

Differences between the Pirh2 and Mdm2 in response to DNA damage

Gene dosage and aging in lung tumorigenesis in p53 (273H) transgenic mice

Valproic acts as an HDAC inhibitor in cells and works synergistically with the DNMT inhibitor, 5-aza-2′-deoxycytidine

Over expression of Pirh2 and concomitant reduction of p53 are associated with lung adenocarcinoma

DNA Methyltransferase Inhibition Enhances Apoptosis Induced by Histone Deacetylase Inhibitors

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