1-20 of 28
Grazia Ambrosini
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Abstract 1852: G protein-coupled estrogen receptor-1 agonist LNS8801 induces mitotic arrest and cell death in uveal melanoma cells

Grazia Ambrosini, Christopher A. Natale, Gary K. Schwartz
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1852.
https://doi.org/10.1158/1538-7445.AM2022-1852
Published: 15 June 2022
View article titled, Abstract 1852: G protein-coupled estrogen receptor-1 agonist LNS8801 induces mitotic arrest and cell death in uveal melanoma cells
Journal Articles

Abstract 1115: BET bromodomain inhibition synergizes with MEK inhibitors in uveal melanoma

Grazia Ambrosini, Elgilda Musi, Gary K. Schwartz
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1115.
https://doi.org/10.1158/1538-7445.AM2021-1115
Published: 01 July 2021
View article titled, Abstract 1115: BET bromodomain inhibition synergizes with MEK inhibitors in uveal melanoma
Journal Articles

Abstract 6082: Uveal melanoma exosomes express MET and re-program the recipient cells

Grazia Ambrosini, Alex J. Rai, Blake Ebert, Gary K. Schwartz
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 6082.
https://doi.org/10.1158/1538-7445.AM2020-6082
Published: 15 August 2020
View article titled, Abstract 6082: Uveal melanoma exosomes express MET and re-program the recipient cells
Journal Articles

Inhibition of NF-κB–Dependent Signaling Enhances Sensitivity and Overcomes Resistance to BET Inhibition in Uveal Melanoma

Grazia Ambrosini, Catherine Do, Benjamin Tycko, Ronald B. Realubit, Charles Karan, Elgilda Musi, Richard D. Carvajal, Vivian Chua, Andrew E. Aplin, Gary K. Schwartz
Journal: Cancer Research
Cancer Res (2019) 79 (9): 2415–2425.
https://doi.org/10.1158/0008-5472.CAN-18-3177
Published: 01 May 2019
View article titled, Inhibition of NF-κB–Dependent Signaling Enhances Sensitivity and Overcomes Resistance to BET Inhibition in Uveal Melanoma
Open the PDF for Inhibition of NF-κB–Dependent Signaling Enhances Sensitivity and Overcomes Resistance to BET Inhibition in Uveal Melanoma in another window
Includes: Supplementary data
Journal Articles

Abstract 5784: A novel ERK inhibitor in the treatment of uveal melanoma

Elgilda Musi, Grazia Ambrosini, Joanne Munck, Gary K. Schwartz
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5784.
https://doi.org/10.1158/1538-7445.AM2018-5784
Published: 01 July 2018
View article titled, Abstract 5784: A novel ERK inhibitor in the treatment of uveal melanoma
Journal Articles

Abstract 4154: Resistance to BET inhibitors involves the β-catenin pathway in uveal melanoma

Grazia Ambrosini, Benjamin Tycko, Chaterine Do, Gary K. Schwartz
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4154.
https://doi.org/10.1158/1538-7445.AM2017-4154
Published: 01 July 2017
View article titled, Abstract 4154: Resistance to BET inhibitors involves the β-catenin pathway in uveal melanoma
Journal Articles

Abstract 291: Sequential treatment with the Wee1 inhibitor, AZD1775, enhances the effect of trabectedin in the L-sarcomas

Elgilda Musi, Grazia Ambrosini, Gary K. Schwartz
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 291.
https://doi.org/10.1158/1538-7445.AM2017-291
Published: 01 July 2017
View article titled, Abstract 291: Sequential treatment with the Wee1 inhibitor, AZD1775, enhances the effect of trabectedin in the L-sarcomas
Journal Articles

Abstract 4462: Cytotoxic effects of a novel BRD4 inhibitor in uveal melanoma cells with Gnaq/11 mutations

Grazia Ambrosini, Gary K. Schwartz
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4462.
https://doi.org/10.1158/1538-7445.AM2016-4462
Published: 15 July 2016
View article titled, Abstract 4462: Cytotoxic effects of a novel BRD4 inhibitor in uveal melanoma cells with Gnaq/11 mutations
Journal Articles

Abstract 4120: c-Met inhibition blocks MEK-induced tumor cell invasion in uveal melanoma

Oliver Surriga, Bryan D. Smith, Grazia Ambrosini, Daniel L. Flynn, Richard D. Carvajal, Gary K. Schwartz
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4120.
https://doi.org/10.1158/1538-7445.AM2016-4120
Published: 15 July 2016
View article titled, Abstract 4120: c-Met inhibition blocks MEK-induced tumor cell invasion in uveal melanoma
Journal Articles

Abstract B29: Differential effects of BRD4 inhibition on uveal melanoma cells with Gnaq/11 mutations

Grazia Ambrosini
Journal: Cancer Research
Cancer Res (2015) 75 (14_Supplement): B29.
https://doi.org/10.1158/1538-7445.MEL2014-B29
Published: 16 July 2015
View article titled, Abstract B29: Differential effects of BRD4 inhibition on uveal melanoma cells with Gnaq/11 mutations
Journal Articles

Abstract B33: PKC resistance in uveal melanoma is mediated by activation of AKT and reversed by BYL719, the PI3Kα inhibitor

Elgilda Musi, Grazia Ambrosini, Gary K. Schwartz
Journal: Cancer Research
Cancer Res (2015) 75 (14_Supplement): B33.
https://doi.org/10.1158/1538-7445.MEL2014-B33
Published: 16 July 2015
View article titled, Abstract B33: PKC resistance in uveal melanoma is mediated by activation of AKT and reversed by BYL719, the PI3Kα inhibitor
Journal Articles

Abstract 2926: PNA as novel targeted cancer therapy for BRAFV600E mutant melanoma

Jeffrey H. Rothman, Oliver Surriga, Shyamprasad D. Vasudeva, Grazia Ambrosini, Ouathek Ouerfelli, Gary K. Schwartz
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2926.
https://doi.org/10.1158/1538-7445.AM2014-2926
Published: 01 October 2014
View article titled, Abstract 2926: PNA as novel targeted cancer therapy for BRAF<sup>V600E</sup> mutant melanoma
Journal Articles

Abstract 1410: Gnaq/11 mutant uveal melanoma is susceptible to Brd4 inhibition by JQ1

Grazia Ambrosini, Gary K. Schwartz
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1410.
https://doi.org/10.1158/1538-7445.AM2014-1410
Published: 01 October 2014
View article titled, Abstract 1410: Gnaq/11 mutant uveal melanoma is susceptible to Brd4 inhibition by JQ1
Journal Articles

Abstract 2073: The parp inhibitor olaparib (AZD2281) greatly enances the effect of temozolomide in soft tissue sarcoma cell lines.

Elgilda Musi, Grazia Ambrosini, Gary K. Schwartz
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2073.
https://doi.org/10.1158/1538-7445.AM2013-2073
Published: 15 April 2013
View article titled, Abstract 2073: The parp inhibitor olaparib (AZD2281) greatly enances the effect of temozolomide in soft tissue sarcoma cell lines.
Journal Articles

Abstract 2706: Crizotinib, a selective c-Met inhibitor, prevents metastasis to the liver and lungs in a primary uveal melanoma mouse model.

Oliver Surriga, Rajasekhar Vinagolu, Grazia Ambrosini, Gary Schwartz
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2706.
https://doi.org/10.1158/1538-7445.AM2013-2706
Published: 15 April 2013
View article titled, Abstract 2706: Crizotinib, a selective c-Met inhibitor, prevents metastasis to the liver and lungs in a primary uveal melanoma mouse model.
Journal Articles

Abstract 5035: The MEK inhibitor AZD6244 is active in GNAQ mutant ocular melanoma cells

Grazia Ambrosini, Gary K. Schwartz
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5035.
https://doi.org/10.1158/1538-7445.AM10-5035
Published: 15 April 2010
View article titled, Abstract 5035: The MEK inhibitor AZD6244 is active in GNAQ mutant ocular melanoma cells
Journal Articles

Differentiation-Related Gene-1 Decreases Bim Stability by Proteasome-Mediated Degradation

Grazia Ambrosini, Sharon L. Seelman, Gary K. Schwartz
Journal: Cancer Research
Cancer Res (2009) 69 (15): 6115–6121.
https://doi.org/10.1158/0008-5472.CAN-08-3024
Published: 29 July 2009
View article titled, Differentiation-Related Gene-1 Decreases Bim Stability by Proteasome-Mediated Degradation
Open the PDF for Differentiation-Related Gene-1 Decreases Bim Stability by Proteasome-Mediated Degradation in another window
Includes: Supplementary data
Journal Articles

The Cyclin-Dependent Kinase Inhibitor Flavopiridol Potentiates the Effects of Topoisomerase I Poisons by Suppressing Rad51 Expression in a p53-Dependent Manner

Grazia Ambrosini, Sharon L. Seelman, Li-Xuan Qin, Gary K. Schwartz
Journal: Cancer Research
Cancer Res (2008) 68 (7): 2312–2320.
https://doi.org/10.1158/0008-5472.CAN-07-2395
Published: 01 April 2008
View article titled, The Cyclin-Dependent Kinase Inhibitor Flavopiridol Potentiates the Effects of Topoisomerase I Poisons by Suppressing Rad51 Expression in a p53-Dependent Manner
Open the PDF for The Cyclin-Dependent Kinase Inhibitor Flavopiridol Potentiates the Effects of Topoisomerase I Poisons by Suppressing Rad51 Expression in a p53-Dependent Manner in another window
Includes: Supplementary data
Journal Articles

Gene Expression Profiling of Liposarcoma Identifies Distinct Biological Types/Subtypes and Potential Therapeutic Targets in Well-Differentiated and Dedifferentiated Liposarcoma

Samuel Singer, Nicholas D. Socci, Grazia Ambrosini, Elliot Sambol, Penelope Decarolis, Yuhsin Wu, Rachael O'Connor, Robert Maki, Agnes Viale, Chris Sander, Gary K. Schwartz, Cristina R. Antonescu
Journal: Cancer Research
Cancer Res (2007) 67 (14): 6626–6636.
https://doi.org/10.1158/0008-5472.CAN-07-0584
Published: 17 July 2007
View article titled, Gene Expression Profiling of Liposarcoma Identifies Distinct Biological Types/Subtypes and Potential Therapeutic Targets in Well-Differentiated and Dedifferentiated Liposarcoma
Open the PDF for Gene Expression Profiling of Liposarcoma Identifies Distinct Biological Types/Subtypes and Potential Therapeutic Targets in Well-Differentiated and Dedifferentiated Liposarcoma in another window
Includes: Supplementary data
Journal Articles

The cyclin dependent kinase inhibitor flavopiridol potentiates the effects of Topo I poisons by suppressing Rad51 expression in a p53-dependent manner.

Grazia Ambrosini, Sharon Seelman, Haider Cheema, Gary Schwartz
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 5397.
Published: 01 May 2007
View article titled, The cyclin dependent kinase inhibitor flavopiridol potentiates the effects of Topo I poisons by suppressing Rad51 expression in a p53-dependent manner.