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Gopesh Srivastava
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Journal Articles

KRAB Zinc Finger Protein ZNF382 Is a Proapoptotic Tumor Suppressor That Represses Multiple Oncogenes and Is Commonly Silenced in Multiple Carcinomas

Yingduan Cheng, Hua Geng, Suk Hang Cheng, Pei Liang, Yan Bai, Jisheng Li, Gopesh Srivastava, Margaret H.L. Ng, Tatsuo Fukagawa, Xiushan Wu, Anthony T.C. Chan, Qian Tao
Journal: Cancer Research
Cancer Res (2010) 70 (16): 6516–6526.
https://doi.org/10.1158/0008-5472.CAN-09-4566
Published: 14 August 2010
View article titled, KRAB Zinc Finger Protein ZNF382 Is a Proapoptotic Tumor Suppressor That Represses Multiple Oncogenes and Is Commonly Silenced in Multiple Carcinomas
Open the PDF for KRAB Zinc Finger Protein ZNF382 Is a Proapoptotic Tumor Suppressor That Represses Multiple Oncogenes and Is Commonly Silenced in Multiple Carcinomas in another window
Includes: Supplementary data
Journal Articles

Extracellular Protease ADAMTS9 Suppresses Esophageal and Nasopharyngeal Carcinoma Tumor Formation by Inhibiting Angiogenesis

Paulisally Hau Yi Lo, Hong Lok Lung, Arthur Kwok Leung Cheung, Suneel S. Apte, Kwok Wah Chan, Fung Mei Kwong, Josephine Mun Yee Ko, Yue Cheng, Simon Law, Gopesh Srivastava, Eugene R. Zabarovsky, Sai Wah Tsao, Johnny Cheuk On Tang, Eric J. Stanbridge, Maria Li Lung
Journal: Cancer Research
Cancer Res (2010) 70 (13): 5567–5576.
https://doi.org/10.1158/0008-5472.CAN-09-4510
Published: 30 June 2010
View article titled, Extracellular Protease <em>ADAMTS9</em> Suppresses Esophageal and Nasopharyngeal Carcinoma Tumor Formation by Inhibiting Angiogenesis
Open the PDF for Extracellular Protease <em>ADAMTS9</em> Suppresses Esophageal and Nasopharyngeal Carcinoma Tumor Formation by Inhibiting Angiogenesis in another window
Includes: Supplementary data
Journal Articles

Abstract 258: Molecular features and functional consequence of CD44 activation by a novel recurrent IGH translocation t(11;14) (p13;q32) in mature B-cell lymphoid neoplasm

Yun-Wen Chen, Xiao-Tong Hu, Anthony C.T. Liang, Michelle L.Y. Wong, Wing-Yan Au, Kai-Yau Wong, William W.L. Choi, Thomas S.K. Wan, Kent-Man Chu, Chor Sang Chim, Li Chong Chan, Yok-Lam Kwong, Raymond H.S. Liang, Gopesh Srivastava
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 258.
https://doi.org/10.1158/1538-7445.AM10-258
Published: 15 April 2010
View article titled, Abstract 258: Molecular features and functional consequence of <em>CD44</em> activation by a novel recurrent <em>IGH</em> translocation t(11;14) (p13;q32) in mature B-cell lymphoid neoplasm
Journal Articles

Abstract 195: Functional epigenetics identifies a protein phosphatase-1 regulatory subunit gene as a candidate tumor suppressor frequently silenced by promoter CpG methylation in multiple tumors

Ching Hei Leung, Ka Man Ng, Ada Ho Yan Wong, Jian ming Ying, Gopesh Srivastava, Sing Fai Leung, Anthony Tak Cheung Chan, Qian Tao
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 195.
https://doi.org/10.1158/1538-7445.AM10-195
Published: 15 April 2010
View article titled, Abstract 195: Functional epigenetics identifies a protein phosphatase-1 regulatory subunit gene as a candidate tumor suppressor frequently silenced by promoter CpG methylation in multiple tumors
Journal Articles

CMTM3, Located at the Critical Tumor Suppressor Locus 16q22.1, Is Silenced by CpG Methylation in Carcinomas and Inhibits Tumor Cell Growth through Inducing Apoptosis

Yu Wang, Jisheng Li, Yan Cui, Ting Li, Ka Man Ng, Hua Geng, Henan Li, Xing-sheng Shu, Hongyu Li, Wei Liu, Bing Luo, Qian Zhang, Tony Shu Kam Mok, Wei Zheng, Xiaoyan Qiu, Gopesh Srivastava, Jun Yu, Joseph J.Y. Sung, Anthony T.C. Chan, Dalong Ma, Qian Tao, Wenling Han
Journal: Cancer Research
Cancer Res (2009) 69 (12): 5194–5201.
https://doi.org/10.1158/0008-5472.CAN-08-3694
Published: 15 June 2009
View article titled, <em>CMTM3</em>, Located at the Critical Tumor Suppressor Locus 16q22.1, Is Silenced by CpG Methylation in Carcinomas and Inhibits Tumor Cell Growth through Inducing Apoptosis
Open the PDF for <em>CMTM3</em>, Located at the Critical Tumor Suppressor Locus 16q22.1, Is Silenced by CpG Methylation in Carcinomas and Inhibits Tumor Cell Growth through Inducing Apoptosis in another window
Includes: Supplementary data
Journal Articles

Abstract #LB-170: Genetic and epigenetic alterations in NK-cell malignancies

Yun Wen Chen, Tian Huan Guo, Lok Yee Wong, Gopesh Srivastava
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): LB-170.
Published: 01 May 2009
View article titled, Abstract #LB-170: Genetic and epigenetic alterations in NK-cell malignancies
Journal Articles

Epigenetic identification of the Interferon Regulatory Factor 8 (IRF8) as a functional tumor suppressor silenced in nasopharyngeal, esophageal, and multiple other carcinomas

Hua Geng, Kwan Yeung Lee, Ka Man Ng, Jun Yu, Ada Ho Yan Wong, Jianming Ying, Gopesh Srivastava, Anthony TC Chan, Joseph JY Sung, Qian Tao
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4270.
Published: 01 May 2008
View article titled, Epigenetic identification of the Interferon Regulatory Factor 8 (IRF8) as a functional tumor suppressor silenced in nasopharyngeal, esophageal, and multiple other carcinomas
Journal Articles

Characterization of a Novel Tumor-Suppressor Gene PLCδ1 at 3p22 in Esophageal Squamous Cell Carcinoma

Li Fu, Yan-Ru Qin, Dan Xie, Liang Hu, Dora L. Kwong, Gopesh Srivastava, Sai Wah Tsao, Xin-Yuan Guan
Journal: Cancer Research
Cancer Res (2007) 67 (22): 10720–10726.
https://doi.org/10.1158/0008-5472.CAN-07-2411
Published: 15 November 2007
View article titled, Characterization of a Novel Tumor-Suppressor Gene <em>PLCδ1</em> at 3p22 in Esophageal Squamous Cell Carcinoma
Open the PDF for Characterization of a Novel Tumor-Suppressor Gene <em>PLCδ1</em> at 3p22 in Esophageal Squamous Cell Carcinoma in another window
Journal Articles

Epigenetic subtraction of HCT116 cells deficient in DNA methyltransferases identify DLC1L1 - a RhoA-GAP, as a novel tumor suppressor silenced by methylation in colorectal and other types of carcinomas

Jianming Ying, Hongyu Li, Hongchuan Jin, Gopesh Srivastava, Sun Young Rha, Anthony Chan, Qian Tao
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 2865.
Published: 01 May 2007
View article titled, Epigenetic subtraction of HCT116 cells deficient in DNA methyltransferases identify <em>DLC1L1</em> - a RhoA-GAP, as a novel tumor suppressor silenced by methylation in colorectal and other types of carcinomas
Journal Articles

Integrative epigenetics identifies a novel 16q23 tumor suppressor gene ADAMTS18 silenced by methylation in multiple tumors

hongchuan jin, Xian Wang, Jianming Ying, Ada HY Wong, Kwan Yeung Lee, Gopesh Srivastava, Zhongying Shen, Liyan Xu, Anthony TC Chan, Qian Tao
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 240.
Published: 01 May 2007
View article titled, Integrative epigenetics identifies a novel 16q23 tumor suppressor gene <em>ADAMTS18</em> silenced by methylation in multiple tumors
Journal Articles

Epigenetic silencing of a Ras-antagonist RASAL1 acts as a new mechanism of Ras activation in human cancers

hongchuan jin, Xian Wang, Jianming Ying, Ada HY Wong, Gopesh Srivastava, Sabine Kupzig, Anthony TC Chan, Peter J Cullen, Qian Tao
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 1111.
Published: 01 May 2007
View article titled, Epigenetic silencing of a Ras-antagonist <em>RASAL1</em> acts as a new mechanism of Ras activation in human cancers
Journal Articles

In vitro and in vivo activity of arsenic trioxide in non-Hodgkin lymphoma.

Wing Y. Au, Rico K H Lo, Chit Chow, Cyrus R. Kumana, Gopesh Srivastava, Raymond H. Liang, Yok-Lam Kwong
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1238.
Published: 15 April 2006
View article titled, <em>In vitro</em> and <em>in vivo</em> activity of arsenic trioxide in non-Hodgkin lymphoma.
Journal Articles

Frequent epigenetic inactivation of Wnt inhibitory factor-1 (WIF-1) in nasopharyngeal, esophageal and breast carcinomas

Lam Chan, Yan Cui, Hongyu Li, Andrew Van Hasselt, Gopesh Srivastava, Keith D Robertson, Sun Yong Rha, Wen-Son Hsieh, Winnie Yeo, Anthony T.c. Chan, Qian Tao
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 376.
Published: 15 April 2006
View article titled, Frequent epigenetic inactivation of Wnt inhibitory factor-1 (<em>WIF-1</em>) in nasopharyngeal, esophageal and breast carcinomas
Journal Articles

Genome-wide identification of novel regions of DNA copy number alterations in natural killer cell lymphoma by array comparative genomic hybridization

Ivy F. Tsui, Javeed Iqbal, Ronald J. Deleeuw, Gopesh Srivastava, Norio Shimizu, Wing C. Chan, Wan L. Lam
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 613–614.
Published: 15 April 2006
View article titled, Genome-wide identification of novel regions of DNA copy number alterations in natural killer cell lymphoma by array comparative genomic hybridization
Journal Articles

Study of transforming capacity of two novel genes JS-1 and JS-2 in chromosome 5p and their overexpression in human esophageal squamous cell carcinoma

Sarwat Fatima, Kin S. Hui, Mei M. Wong, Wing K. Tang, Chung H. Chui, John Wong, Simon Law, George S. W. Tsao, King Y. Lam, Gopesh Srivastava, Kwok P. Ho, Johnny C. O. Tang
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 447.
Published: 01 May 2005
View article titled, Study of transforming capacity of two novel genes JS-1 and JS-2 in chromosome 5p and their overexpression in human esophageal squamous cell carcinoma
Journal Articles

Functional localization of tumor suppressive regions on chromosome 3 in esophageal carcinoma

Maria L. Lung, Paulisally H. Lo, Johnny Cheuk On Tang, Gopesh Srivastava, Eric J. Stanbridge
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 376.
Published: 01 April 2004
View article titled, Functional localization of tumor suppressive regions on chromosome 3 in esophageal carcinoma
Journal Articles

A novel tumor transforming gene at 7q22, GAESCC1, is frequently amplified and overexpressed in primary esophageal squamous cell carcinomas.

Fian B. F. Law, Gopesh Srivastava, Y. W. Chen, Anthony C. T. Liang, K. Y. Wong, K. Y. Lam, Simon Law, John Wong, Johnny C. O. Tang
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 796.
Published: 01 April 2004
View article titled, A novel tumor transforming gene at 7q22, <em>GAESCC1</em>, is frequently amplified and overexpressed in primary esophageal squamous cell carcinomas.