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Journal Articles

Abstract 3898: Integrating structural variants and single nucleotide variants to uncover evolutionary trajectories in melanoma

Xiwen Cui, Ayse G. Keskus, Salem Malikic, Yuelin Liu, Anton Goretsky, Chi-Ping Day, Farid R. Mehrabadi, Mikhail Kolmogorov, Glenn Merlino, S. Cenk Sahinalp

Cancer Res (2025) 85 (8_Supplement_1): 3898.

https://doi.org/10.1158/1538-7445.AM2025-3898

Published: 21 April 2025

View articletitled, Abstract 3898: Integrating structural variants and single nucleotide variants to uncover evolutionary trajectories in melanoma

Journal Articles

Abstract 7497: Nanopore sequencing of single-cell derived sublines provides insights into melanoma heterogeneity and evolution

Anton Goretsky, Yuelin Liu, Ayse Keskus, Tanveer Ahmad, Salem Malikic, Glenn Merlino, Chi-Ping Day, Erin Molloy, S. Cenk Sahinalp, Mikhail Kolmogorov

Cancer Res (2025) 85 (8_Supplement_1): 7497.

https://doi.org/10.1158/1538-7445.AM2025-7497

Published: 21 April 2025

View articletitled, Abstract 7497: Nanopore sequencing of single-cell derived sublines provides insights into melanoma heterogeneity and evolution

Journal Articles

Abstract A002: Dissecting the brain metastatic microenvironment to uncover immune and molecular correlates of response to immunotherapy

Cancer Res (2024) 84 (22_Supplement): A002.

https://doi.org/10.1158/1538-7445.TUMBODY-A002

Published: 17 November 2024

View articletitled, Abstract A002: Dissecting the brain metastatic microenvironment to uncover immune and molecular correlates of response to immunotherapy

Journal Articles

Abstract LB233: Single-cell transcriptional analysis of embryonic melanoblasts pinpoints embryonic cell states that underlie targeted therapy and immune checkpoint blockade resistance

Vishaka Gopalan, Chun Wai Wong, Chi-Ping Day, Eva Perez-Guijarro, Maxwell P. Lee, Yuhong Jiang, Howard H. Yang, Maira Alves-Constantino, Antonella Sassano, Cari Smith, Mark Simpson, Sung Chin, Jessica Ebersole, Charli Gruen, Emily Wu, Sridhar Hannenhalli, Adam Hurlstone, Glenn Merlino, Kerrie Marie

Cancer Res (2024) 84 (7_Supplement): LB233.

https://doi.org/10.1158/1538-7445.AM2024-LB233

Published: 05 April 2024

View articletitled, Abstract LB233: Single-cell transcriptional analysis of embryonic melanoblasts pinpoints embryonic cell states that underlie targeted therapy and immune checkpoint blockade resistance

Journal Articles

Abstract 7407: Melanoma clonal subline analysis reveals genetic factors driving intra-tumor heterogeneity

Ayse Keskus, Anton Goretsky, Yuelin Liu, Xiwen Cui, Tanveer Ahmad, Eva Perez Guijarro, Asher Bryant, Erin Malloy, Salem Malikic, Glenn Merlino, Chi-Ping Day, Cenk Sahinalp, Mikhail Kolmogorov

Cancer Res (2024) 84 (6_Supplement): 7407.

https://doi.org/10.1158/1538-7445.AM2024-7407

Published: 22 March 2024

View articletitled, Abstract 7407: Melanoma clonal subline analysis reveals genetic factors driving intra-tumor heterogeneity

Journal Articles

Abstract 6924: Structural variant dynamics in melanoma: Unraveling tumor heterogeneity and evolution

Xiwen Cui, Ayse G. Keskus, Farid R. Mehrabadi, Salem Malikic, Mikhail Kolmogorov, Chi-Ping Day, Glenn Merlino, S. Cenk Sahinalp

Cancer Res (2024) 84 (6_Supplement): 6924.

https://doi.org/10.1158/1538-7445.AM2024-6924

Published: 22 March 2024

View articletitled, Abstract 6924: Structural variant dynamics in melanoma: Unraveling tumor heterogeneity and evolution

Journal Articles

Abstract 1337: Characterization of anti-AXL CAR-NK cell therapy for the treatment of melanoma

Winston Hibler, Glenn Merlino, Yan Lin Yu

Cancer Res (2024) 84 (6_Supplement): 1337.

https://doi.org/10.1158/1538-7445.AM2024-1337

Published: 22 March 2024

View articletitled, Abstract 1337: Characterization of anti-AXL CAR-NK cell therapy for the treatment of melanoma

Journal Articles

Abstract 5869: Investigation of molecular alterations associated with double resistance to BRAF and MEK inhibition in melanoma

Armond J. Isaak, GeGe R. Clements, Lei Huang, Yifei Qin, Qiang Zho, Glenn Merlino, Yanlin Yu

Cancer Res (2024) 84 (6_Supplement): 5869.

https://doi.org/10.1158/1538-7445.AM2024-5869

Published: 22 March 2024

View articletitled, Abstract 5869: Investigation of molecular alterations associated with double resistance to BRAF and MEK inhibition in melanoma

Journal Articles

Abstract 4648: Metabolic vulnerabilities of drug-resistant melanoma with therapeutic potential

Yanlin Yu, Lei Huang, Weiping Chen, Glenn Merlino

Cancer Res (2024) 84 (6_Supplement): 4648.

https://doi.org/10.1158/1538-7445.AM2024-4648

Published: 22 March 2024

View articletitled, Abstract 4648: Metabolic vulnerabilities of drug-resistant melanoma with therapeutic potential

Journal Articles

Abstract 4148: Extracellular matrix biophysical properties change during nevus to melanoma progression

Aditya Kavuturu, Maira A. Constantino, Antonella Sassano, Glenn Merlino

Cancer Res (2024) 84 (6_Supplement): 4148.

https://doi.org/10.1158/1538-7445.AM2024-4148

Published: 22 March 2024

View articletitled, Abstract 4148: Extracellular matrix biophysical properties change during nevus to melanoma progression

Journal Articles

Abstract 5524: Identification of PAEP as an immune activity modulator to mediate the immune resistance in tumor metastasis

Rand Gabriel M. Buenaventura, Weiping Chen, Shuling Zhang, Beverly Mock, Glenn Merlino, Yanlin Yu

Cancer Res (2024) 84 (6_Supplement): 5524.

https://doi.org/10.1158/1538-7445.AM2024-5524

Published: 22 March 2024

View articletitled, Abstract 5524: Identification of PAEP as an immune activity modulator to mediate the immune resistance in tumor metastasis

Journal Articles

Abstract 141: Interrogating subclonal mechanisms of immune evasion and immunotherapy resistance in melanoma

Isabella Church, Charli Gruen, Antonella Sassano, Julio Valencia, Emily Wu, Howard Yang, Gabe Needle, Cari Smith, Sung Chin, Jessica Ebersole, Christina Marcelus, Anyen Fon, Huaitian Liu, Chi-Ping Day, Howard Young, Maxwell Lee, Glenn Merlino, Eva Pérez-Guijarro

Cancer Res (2023) 83 (7_Supplement): 141.

https://doi.org/10.1158/1538-7445.AM2023-141

Published: 04 April 2023

View articletitled, Abstract 141: Interrogating subclonal mechanisms of immune evasion and immunotherapy resistance in melanoma

Journal Articles

Abstract 5188: Interrogating the role of the immune microenvironment in the response of brain metastases to immunotherapy using new preclinical melanoma models

Amélie Lopès, Jessica Rappaport, Eva Pérez Guijarro, Quanyi Chen, Emily Wu, Isabella Church, April Huang, Jessica Bridge, Sung Chin, Cari Smith, Charli Gruen, Khiem C. Lam, Romina E. Araya, Antonella Sassano, Chi-Ping Day, Glenn Merlino, Romina S. Goldszmid

Cancer Res (2023) 83 (7_Supplement): 5188.

https://doi.org/10.1158/1538-7445.AM2023-5188

Published: 04 April 2023

View articletitled, Abstract 5188: Interrogating the role of the immune microenvironment in the response of brain metastases to immunotherapy using new preclinical melanoma models

Journal Articles

Abstract 3825: Germline modifiers of the tumor immune microenvironment reveal drivers of immunotherapy response

Cancer Res (2022) 82 (12_Supplement): 3825.

https://doi.org/10.1158/1538-7445.AM2022-3825

Published: 15 June 2022

View articletitled, Abstract 3825: Germline modifiers of the tumor immune microenvironment reveal drivers of immunotherapy response

Journal Articles

Abstract 576: Shark V_NAR single domain-based CAR T cells targeting PD-L1 for cancer therapy

Dan Li, Hejiao English, Jessica Hong, Tianyuzhou Liang, Glenn Merlino, Chi-Ping Day, Mitchell Ho

Cancer Res (2022) 82 (12_Supplement): 576.

https://doi.org/10.1158/1538-7445.AM2022-576

Published: 15 June 2022

View articletitled, Abstract 576: Shark VNAR single domain-based CAR T cells targeting PD-L1 for cancer therapy

Journal Articles

Myeloid-Derived Suppressive Cell Expansion Promotes Melanoma Growth and Autoimmunity by Inhibiting CD40/IL27 Regulation in Macrophages

Cancer Res (2021) 81 (23): 5977–5990.

https://doi.org/10.1158/0008-5472.CAN-21-1148

Published: 01 December 2021

View articletitled, Myeloid-Derived Suppressive Cell Expansion Promotes Melanoma Growth and Autoimmunity by Inhibiting CD40/IL27 Regulation in Macrophages

Includes: Supplementary data

Journal Articles

Abstract LB019: Trisicell: Scalable Tumor Phylogeny Reconstruction and Validation Reveals Developmental Origin and Therapeutic Impact of Intratumoral Heterogeneity

Farid Rashidi Mehrabadi, Salem Malikić, Kerrie L. Marie, Eva Pérez-Guijarro, Erfan Sadeqi Azer, Howard H. Yang, Can Kızılkale, Charli Gruen, Huaitian Liu, Christina Marcelus, Aydın Buluç, Funda Ergün, Maxwell P. Lee, Glenn Merlino, Chi-Ping Day, S. Cenk Sahinalp

Cancer Res (2021) 81 (13_Supplement): LB019.

https://doi.org/10.1158/1538-7445.AM2021-LB019

Published: 01 July 2021

View articletitled, Abstract LB019: Trisicell: Scalable Tumor Phylogeny Reconstruction and Validation Reveals Developmental Origin and Therapeutic Impact of Intratumoral Heterogeneity

Journal Articles

Abstract IA07: UVB-induced tumor heterogeneity directs immune response in melanoma

Osnat Bartok, Sushant Patkar, Sapir Cohen, Kevin Litchfield, Hiren Karathia, Joo Sang Lee, Alejandro Jiménez-Sánchez, Chi-Ping Day, Lea Eisenbach, Martin Miller, Glenn Merlino, Eli Pikarsky, Arie Admon, Charles Swanton, Eytan Ruppin, Yardena Samuels, Yochai Wolf

Cancer Res (2020) 80 (21_Supplement): IA07.

https://doi.org/10.1158/1538-7445.TUMHET2020-IA07

Published: 03 November 2020

View articletitled, Abstract IA07: UVB-induced tumor heterogeneity directs immune response in melanoma

Journal Articles

Build-a-Mouse: Melanoma Modeling Picks up Speed

Andres Thorkelsson, Glenn Merlino, Helen Michael

Cancer Res (2020) 80 (4): 655–656.

https://doi.org/10.1158/0008-5472.CAN-19-3869

Published: 14 February 2020

View articletitled, Build-a-Mouse: Melanoma Modeling Picks up Speed

Journal Articles

Abstract 5678: Developing a preclinical immunotherapy platform using syngeneic mouse models of human melanoma

Corinne Rauck, Eva Perez-Guijarro, Zoe W. Ohler, Rajaa El E. Meskini, Howard Yang, Suman Vodnala, Cari Graff-Cherry, Sung Chin, Anyen Fon, Helen Michael, Maxwell Lee, Terry Van Dyke, Shyam Sharan, Glenn Merlino, Chi-Ping Day

Cancer Res (2018) 78 (13_Supplement): 5678.

https://doi.org/10.1158/1538-7445.AM2018-5678

Published: 01 July 2018

View articletitled, Abstract 5678: Developing a preclinical immunotherapy platform using syngeneic mouse models of human melanoma

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Abstract 3898: Integrating structural variants and single nucleotide variants to uncover evolutionary trajectories in melanoma

Abstract 7497: Nanopore sequencing of single-cell derived sublines provides insights into melanoma heterogeneity and evolution

Abstract A002: Dissecting the brain metastatic microenvironment to uncover immune and molecular correlates of response to immunotherapy

Abstract LB233: Single-cell transcriptional analysis of embryonic melanoblasts pinpoints embryonic cell states that underlie targeted therapy and immune checkpoint blockade resistance

Abstract 7407: Melanoma clonal subline analysis reveals genetic factors driving intra-tumor heterogeneity

Abstract 6924: Structural variant dynamics in melanoma: Unraveling tumor heterogeneity and evolution

Abstract 1337: Characterization of anti-AXL CAR-NK cell therapy for the treatment of melanoma

Abstract 5869: Investigation of molecular alterations associated with double resistance to BRAF and MEK inhibition in melanoma

Abstract 4648: Metabolic vulnerabilities of drug-resistant melanoma with therapeutic potential

Abstract 4148: Extracellular matrix biophysical properties change during nevus to melanoma progression

Abstract 5524: Identification of PAEP as an immune activity modulator to mediate the immune resistance in tumor metastasis

Abstract 141: Interrogating subclonal mechanisms of immune evasion and immunotherapy resistance in melanoma

Abstract 5188: Interrogating the role of the immune microenvironment in the response of brain metastases to immunotherapy using new preclinical melanoma models

Abstract 3825: Germline modifiers of the tumor immune microenvironment reveal drivers of immunotherapy response

Abstract 576: Shark V_NAR single domain-based CAR T cells targeting PD-L1 for cancer therapy

Myeloid-Derived Suppressive Cell Expansion Promotes Melanoma Growth and Autoimmunity by Inhibiting CD40/IL27 Regulation in Macrophages

Abstract LB019: Trisicell: Scalable Tumor Phylogeny Reconstruction and Validation Reveals Developmental Origin and Therapeutic Impact of Intratumoral Heterogeneity

Abstract IA07: UVB-induced tumor heterogeneity directs immune response in melanoma

Build-a-Mouse: Melanoma Modeling Picks up Speed

Abstract 5678: Developing a preclinical immunotherapy platform using syngeneic mouse models of human melanoma

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