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Abstract 576: Shark V_NAR single domain-based CAR T cells targeting PD-L1 for cancer therapy

Dan Li, Hejiao English, Jessica Hong, Tianyuzhou Liang, Glenn Merlino, Chi-Ping Day, Mitchell Ho

Cancer Res (2022) 82 (12_Supplement): 576.

DOI: https://doi.org/10.1158/1538-7445.AM2022-576

Published: 15 June 2022

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Journal Articles

Abstract 3825: Germline modifiers of the tumor immune microenvironment reveal drivers of immunotherapy response

Cancer Res (2022) 82 (12_Supplement): 3825.

DOI: https://doi.org/10.1158/1538-7445.AM2022-3825

Published: 15 June 2022

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Journal Articles

Myeloid-Derived Suppressive Cell Expansion Promotes Melanoma Growth and Autoimmunity by Inhibiting CD40/IL27 Regulation in Macrophages

Cancer Res (2021) 81 (23): 5977–5990.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-1148

Published: 01 December 2021

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Includes: Supplementary data

Journal Articles

Abstract LB019: Trisicell: Scalable Tumor Phylogeny Reconstruction and Validation Reveals Developmental Origin and Therapeutic Impact of Intratumoral Heterogeneity

Farid Rashidi Mehrabadi, Salem Malikić, Kerrie L. Marie, Eva Pérez-Guijarro, Erfan Sadeqi Azer, Howard H. Yang, Can Kızılkale, Charli Gruen, Huaitian Liu, Christina Marcelus, Aydın Buluç, Funda Ergün, Maxwell P. Lee, Glenn Merlino, Chi-Ping Day, S. Cenk Sahinalp

Cancer Res (2021) 81 (13_Supplement): LB019.

DOI: https://doi.org/10.1158/1538-7445.AM2021-LB019

Published: 01 July 2021

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Journal Articles

Abstract IA07: UVB-induced tumor heterogeneity directs immune response in melanoma

Osnat Bartok, Sushant Patkar, Sapir Cohen, Kevin Litchfield, Hiren Karathia, Joo Sang Lee, Alejandro Jiménez-Sánchez, Chi-Ping Day, Lea Eisenbach, Martin Miller, Glenn Merlino, Eli Pikarsky, Arie Admon, Charles Swanton, Eytan Ruppin, Yardena Samuels, Yochai Wolf

Cancer Res (2020) 80 (21_Supplement): IA07.

DOI: https://doi.org/10.1158/1538-7445.TUMHET2020-IA07

Published: 03 November 2020

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Journal Articles

Build-a-Mouse: Melanoma Modeling Picks up Speed

Andres Thorkelsson, Glenn Merlino, Helen Michael

Cancer Res (2020) 80 (4): 655–656.

DOI: https://doi.org/10.1158/0008-5472.CAN-19-3869

Published: 14 February 2020

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Journal Articles

Abstract 5678: Developing a preclinical immunotherapy platform using syngeneic mouse models of human melanoma

Corinne Rauck, Eva Perez-Guijarro, Zoe W. Ohler, Rajaa El E. Meskini, Howard Yang, Suman Vodnala, Cari Graff-Cherry, Sung Chin, Anyen Fon, Helen Michael, Maxwell Lee, Terry Van Dyke, Shyam Sharan, Glenn Merlino, Chi-Ping Day

Cancer Res (2018) 78 (13_Supplement): 5678.

DOI: https://doi.org/10.1158/1538-7445.AM2018-5678

Published: 01 July 2018

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Journal Articles

Abstract 5720: Functional characterization of neoantigens determining immune checkpoint blockade response in mouse models of human melanoma

Eva Perez Guijarro, Chi-Ping Day, Zoe W. Ohler, Rajaa El Meskini, Howard Yang, Suman Vodnala, Cari Graff-Cherry, Sung Chin, Anyen Fon, Helen Michael, Maxwell Lee, Terry Van Dyke, Shyam Sharan, Glenn Merlino

Cancer Res (2018) 78 (13_Supplement): 5720.

DOI: https://doi.org/10.1158/1538-7445.AM2018-5720

Published: 01 July 2018

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Journal Articles

Abstract 2623: Identification of neo-antigens driving melanoma response to immune checkpoint blockers via in vivo screening

Chi-Ping Day, Eva Perez-Guijarro, Rajaa El Meskini, Zoe Weaver Ohler, Maxwell Lee, Howard Yang, Suman Vodnala, Shyam Sharan, Glenn Merlino

Cancer Res (2017) 77 (13_Supplement): 2623.

DOI: https://doi.org/10.1158/1538-7445.AM2017-2623

Published: 01 July 2017

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Journal Articles

Abstract 1037: Progression from melanocytic nevi to melanoma is associated with increased genomic mutations in a UV-induced mouse model of human melanoma

Helen Michael, Chi-Ping Day, Howard Yang, Aleksandra Michalowski, Maxwell Lee, Glenn Merlino

Cancer Res (2017) 77 (13_Supplement): 1037.

DOI: https://doi.org/10.1158/1538-7445.AM2017-1037

Published: 01 July 2017

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Journal Articles

Concepts in Cancer Modeling: A Brief History

Renee M. Thomas, Terry Van Dyke, Glenn Merlino, Chi-Ping Day

Cancer Res (2016) 76 (20): 5921–5925.

DOI: https://doi.org/10.1158/0008-5472.CAN-16-1293

Published: 13 October 2016

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Journal Articles

Abstract 1479: Preclinical model of human melanoma for evaluation of targeted drug treatment and for immunotherapy validation

Rajaa El Meskini, Michelle Gumprecht, Alan Kulaga, Anthony Iacovelli, Terry Van Dyke, Chi-Ping Day, Glenn Merlino, Zoe Weaver Ohler

Cancer Res (2016) 76 (14_Supplement): 1479.

DOI: https://doi.org/10.1158/1538-7445.AM2016-1479

Published: 15 July 2016

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Journal Articles

Abstract 4388: The role of neoantigens in immunotherapy of cutaneous melanoma

Renee M. Thomas, Chi-Ping Day, Zoe Weaver Ohler, Rajaa El Meskini, Carri Graff-Cherry, Sung Chin, Aleksandra Michalowski, Ji Luo, Terry Van Dyke, Glenn Merlino

Cancer Res (2016) 76 (14_Supplement): 4388.

DOI: https://doi.org/10.1158/1538-7445.AM2016-4388

Published: 15 July 2016

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Journal Articles

Abstract 5165: ADAM17: a common effector for RAS and MET-driven transformation of primary keratinocytes

Christophe Cataisson, Mary Klosterman, Kelly Shibuya, Glenn Merlino, Stuart H. Yuspa

Cancer Res (2016) 76 (14_Supplement): 5165.

DOI: https://doi.org/10.1158/1538-7445.AM2016-5165

Published: 15 July 2016

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Journal Articles

Abstract 4114: Blocking Ezrin can inhibit HGF/Met signaling-induced metastasis

Yanlin Yu, Liping Huang, Glenn Merlino

Cancer Res (2016) 76 (14_Supplement): 4114.

DOI: https://doi.org/10.1158/1538-7445.AM2016-4114

Published: 15 July 2016

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Journal Articles

Abstract 994: Integrated embryonic transcriptome analyses identify key melanoma metastasis regulator

Pravin J. Mishra, Theresa Guo, Raza Zaidi, Sean Davis, Aleksandra Michalowski, Helen Michael, William Reinhold, Heinz Arnheiter, Paul Meltzer, Glenn Merlino

Cancer Res (2014) 74 (19_Supplement): 994.

DOI: https://doi.org/10.1158/1538-7445.AM2014-994

Published: 01 October 2014

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Journal Articles

Abstract 1064: The combined activation of MET signaling and PKCα is sufficient to induce tumors in mouse skin.

Christophe Cataisson, Fan Liu, Lisa N. Wright, Anne Zhuang, Glenn Merlino, Stuart H. Yuspa

Cancer Res (2013) 73 (8_Supplement): 1064.

DOI: https://doi.org/10.1158/1538-7445.AM2013-1064

Published: 15 April 2013

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Journal Articles

Abstract 3868: Identification of PHLPP1 as a novel metastasis suppressor in melanoma .

Yanlin Yu, Andrew Lu, Meng Dai, Glenn Merlino

Cancer Res (2013) 73 (8_Supplement): 3868.

DOI: https://doi.org/10.1158/1538-7445.AM2013-3868

Published: 15 April 2013

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Journal Articles

Abstract 1556: Immunological naturalization of immunocompetent host mice to luciferase-GFP for consistent tracking of transplanted tumors.

Chi-Ping Day, Zoe Weaver, John Carter, Carrie Bonomi, Terry Van Dyke, Melinda Hollingshead, Glenn Merlino

Cancer Res (2013) 73 (8_Supplement): 1556.

DOI: https://doi.org/10.1158/1538-7445.AM2013-1556

Published: 15 April 2013

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Journal Articles

Abstract 2994: Using embryonic melanoblast transcriptome analysis to identify novel mechanisms promoting metastatic melanoma.

Pravin J. Mishra, Theresa Guo, Raza Zaidi, Sean Davis, Heinz Arnheiter, William C. Reinhold, Paul Meltzer, Glenn Merlino

Cancer Res (2013) 73 (8_Supplement): 2994.

DOI: https://doi.org/10.1158/1538-7445.AM2013-2994

Published: 15 April 2013

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NARROW

Abstract 576: Shark V_NAR single domain-based CAR T cells targeting PD-L1 for cancer therapy

Abstract 3825: Germline modifiers of the tumor immune microenvironment reveal drivers of immunotherapy response

Myeloid-Derived Suppressive Cell Expansion Promotes Melanoma Growth and Autoimmunity by Inhibiting CD40/IL27 Regulation in Macrophages

Abstract LB019: Trisicell: Scalable Tumor Phylogeny Reconstruction and Validation Reveals Developmental Origin and Therapeutic Impact of Intratumoral Heterogeneity

Abstract IA07: UVB-induced tumor heterogeneity directs immune response in melanoma

Build-a-Mouse: Melanoma Modeling Picks up Speed

Abstract 5678: Developing a preclinical immunotherapy platform using syngeneic mouse models of human melanoma

Abstract 5720: Functional characterization of neoantigens determining immune checkpoint blockade response in mouse models of human melanoma

Abstract 2623: Identification of neo-antigens driving melanoma response to immune checkpoint blockers via in vivo screening

Abstract 1037: Progression from melanocytic nevi to melanoma is associated with increased genomic mutations in a UV-induced mouse model of human melanoma

Concepts in Cancer Modeling: A Brief History

Abstract 1479: Preclinical model of human melanoma for evaluation of targeted drug treatment and for immunotherapy validation

Abstract 4388: The role of neoantigens in immunotherapy of cutaneous melanoma

Abstract 5165: ADAM17: a common effector for RAS and MET-driven transformation of primary keratinocytes

Abstract 4114: Blocking Ezrin can inhibit HGF/Met signaling-induced metastasis

Abstract 994: Integrated embryonic transcriptome analyses identify key melanoma metastasis regulator

Abstract 1064: The combined activation of MET signaling and PKCα is sufficient to induce tumors in mouse skin.

Abstract 3868: Identification of PHLPP1 as a novel metastasis suppressor in melanoma .

Abstract 1556: Immunological naturalization of immunocompetent host mice to luciferase-GFP for consistent tracking of transplanted tumors.

Abstract 2994: Using embryonic melanoblast transcriptome analysis to identify novel mechanisms promoting metastatic melanoma.

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