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Glenn J. Bubley
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Journal Articles

Abstract 973: The selective polo-like kinase (Plk1) inhibitor onvansertib and the antiandrogen abiraterone synergistically kill cancer cells through disruption of mitosis independently of androgen receptor signaling

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Jesse C. Patterson, Peter J. Croucher, Maya Ridinger, David J. Einstein, Andreas Varkaris, Steven P. Balk, Glenn J. Bubley, Mark G. Erlander, Michael B. Yaffe
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 973.
https://doi.org/10.1158/1538-7445.AM2021-973
Published: 01 July 2021
View article titled, Abstract 973: The selective polo-like kinase (Plk1) inhibitor onvansertib and the antiandrogen abiraterone synergistically kill cancer cells through disruption of mitosis independently of androgen receptor signaling
Journal Articles

Abstract 395: Aberrant HER2 signaling is a therapeutic target in a subset of castration-resistant prostate cancer

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Joshua W. Russo, Xin Gao, David J. Einstein, Glenn J. Bubley, Steven P. Balk
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 395.
https://doi.org/10.1158/1538-7445.AM2019-395
Published: 01 July 2019
View article titled, Abstract 395: Aberrant HER2 signaling is a therapeutic target in a subset of castration-resistant prostate cancer
Journal Articles

Neoadjuvant-Intensive Androgen Deprivation Therapy Selects for Prostate Tumor Foci with Diverse Subclonal Oncogenic Alterations

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Adam G. Sowalsky, Huihui Ye, Manoj Bhasin, Eliezer M. Van Allen, Massimo Loda, Rosina T. Lis, Laleh Montaser-Kouhsari, Carla Calagua, Fen Ma, Joshua W. Russo, Rachel J. Schaefer, Olga S. Voznesensky, Zhenwei Zhang, Glenn J. Bubley, Bruce Montgomery, Elahe A. Mostaghel, Peter S. Nelson, Mary-Ellen Taplin, Steven P. Balk
Journal: Cancer Research
Cancer Res (2018) 78 (16): 4716–4730.
https://doi.org/10.1158/0008-5472.CAN-18-0610
Published: 14 August 2018
View article titled, Neoadjuvant-Intensive Androgen Deprivation Therapy Selects for Prostate Tumor Foci with Diverse Subclonal Oncogenic Alterations
Open the PDF for Neoadjuvant-Intensive Androgen Deprivation Therapy Selects for Prostate Tumor Foci with Diverse Subclonal Oncogenic Alterations in another window
Includes: Supplementary data
Journal Articles

Abstract A024: Prostate cancer neoadjuvant intensive androgen deprivation therapy selects for tumor foci with diverse oncogenic alterations

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Adam G. Sowalsky, Huihui Ye, Manoj Bhasin, Eliezer M. Van Allen, Massimo Loda, Rosina T. Lis, Laleh Montaser, Carla Calagua, Fen Ma, Joshua W. Russo, Rachel J. Schaefer, Olga S. Voznesensky, Zhenwei Zhang, Glenn J. Bubley, Robert B. Montgomery, Elahe A. Mostaghel, Peter S. Nelson, Mary-Ellen Taplin, Steven P. Balk
Journal: Cancer Research
Cancer Res (2018) 78 (16_Supplement): A024.
https://doi.org/10.1158/1538-7445.PRCA2017-A024
Published: 14 August 2018
View article titled, Abstract A024: Prostate cancer neoadjuvant intensive androgen deprivation therapy selects for tumor foci with diverse oncogenic alterations
Journal Articles

Clonal Progression of Prostate Cancers from Gleason Grade 3 to Grade 4

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Adam G. Sowalsky, Huihui Ye, Glenn J. Bubley, Steven P. Balk
Journal: Cancer Research
Cancer Res (2013) 73 (3): 1050–1055.
https://doi.org/10.1158/0008-5472.CAN-12-2799
Published: 31 January 2013
View article titled, Clonal Progression of Prostate Cancers from Gleason Grade 3 to Grade 4
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Includes: Supplementary data
Journal Articles

Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors

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Changmeng Cai, Sen Chen, Patrick Ng, Glenn J. Bubley, Peter S. Nelson, Elahe A. Mostaghel, Brett Marck, Alvin M. Matsumoto, Nicholas I. Simon, Hongyun Wang, Shaoyong Chen, Steven P. Balk
Journal: Cancer Research
Cancer Res (2011) 71 (20): 6503–6513.
https://doi.org/10.1158/0008-5472.CAN-11-0532
Published: 12 October 2011
View article titled, Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors
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Includes: Supplementary data
Journal Articles

HIF-1α gene polymorphisms, prediagnostic hormone levels and prostate cancer risk

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Haojie Li, Glenn J. Bubley, Stephen P. Balk, J. Michael Gaziano, Meir J. Stampfer, Jing Ma
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 864.
Published: 15 April 2006
View article titled, HIF-1α gene polymorphisms, prediagnostic hormone levels and prostate cancer risk
Journal Articles

Increased expression of genes converting adrenal androgens to testosterone in androgen independent prostate cancer

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Steven P. Balk, Michael Stanbrough, Glenn J. Bubley, Todd R. Golub, Mark A. Rubin, Kenneth Ross, Trevor M. Penning, Phillip G. Febbo
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 547.
Published: 15 April 2006
View article titled, Increased expression of genes converting adrenal androgens to testosterone in androgen independent prostate cancer
Journal Articles

Increased Expression of Genes Converting Adrenal Androgens to Testosterone in Androgen-Independent Prostate Cancer

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Michael Stanbrough, Glenn J. Bubley, Kenneth Ross, Todd R. Golub, Mark A. Rubin, Trevor M. Penning, Phillip G. Febbo, Steven P. Balk
Journal: Cancer Research
Cancer Res (2006) 66 (5): 2815–2825.
https://doi.org/10.1158/0008-5472.CAN-05-4000
Published: 01 March 2006
View article titled, Increased Expression of Genes Converting Adrenal Androgens to Testosterone in Androgen-Independent Prostate Cancer
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Journal Articles

Selection for Androgen Receptor Mutations in Prostate Cancers Treated with Androgen Antagonist

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Mary-Ellen Taplin, Glenn J. Bubley, Yoo-Joung Ko, Eric J. Small, Melissa Upton, Barur Rajeshkumar, Steven P. Balk
Journal: Cancer Research
Cancer Res (1999) 59 (11): 2511–2515.
Published: 01 June 1999
View article titled, Selection for Androgen Receptor Mutations in Prostate Cancers Treated with Androgen Antagonist
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Journal Articles

Regional Loss of Chromosome 6 in Two Urological Malignancies

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Daniel B. Rukstalis, Glenn J. Bubley, John P. Donahue, Jerome P. Richie, J. G. Seidman, William C. DeWolf
Journal: Cancer Research
Cancer Res (1989) 49 (18): 5087–5090.
Published: 01 September 1989
View article titled, Regional Loss of Chromosome 6 in Two Urological Malignancies
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Journal Articles

Repair of DNA following Incorporation of 1-β-d-Arabinofuranosylcytosine into Herpes Simplex Virus Type I1

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Glenn J. Bubley, Clyde S. Crumpacker, Lowell E. Schnipper
Journal: Cancer Research
Cancer Res (1984) 44 (5): 1813–1818.
Published: 01 May 1984
View article titled, Repair of DNA following Incorporation of 1-β-d-Arabinofuranosylcytosine into Herpes Simplex Virus Type I1
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