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Glen S. Germain
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Journal Articles

The identification and functional analysis of N10-substituted phenoxazines as small molecule inhibitors of Akt signaling

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Kuntebommanahalli N. Thimmaiah, John B. Easton, Glen S. Germain, Christopher L. Morton, Shantaram Kamath, John K. Buolamwini, Peter J. Houghton
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 399.
Published: 01 May 2005
View articletitled, The identification and functional analysis of N10-substituted phenoxazines as small molecule inhibitors of Akt signaling
Journal Articles

Gefitinib Enhances the Antitumor Activity and Oral Bioavailability of Irinotecan in Mice

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Clinton F. Stewart, Markos Leggas, John D. Schuetz, John C. Panetta, Pamela J. Cheshire, Jennifer Peterson, Najat Daw, Jesse J. Jenkins, III, Richard Gilbertson, Glen S. Germain, Franklin C. Harwood, Peter J. Houghton
Journal: Cancer Research
Cancer Res (2004) 64 (20): 7491–7499.
https://doi.org/10.1158/0008-5472.CAN-04-0096
Published: 15 October 2004
View articletitled, Gefitinib Enhances the Antitumor Activity and Oral Bioavailability of Irinotecan in Mice
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Journal Articles

Imatinib Mesylate Is a Potent Inhibitor of the ABCG2 (BCRP) Transporter and Reverses Resistance to Topotecan and SN-38 in Vitro

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Peter J. Houghton, Glen S. Germain, Franklin C. Harwood, John D. Schuetz, Clinton F. Stewart, Elisabeth Buchdunger, Peter Traxler
Journal: Cancer Research
Cancer Res (2004) 64 (7): 2333–2337.
https://doi.org/10.1158/0008-5472.CAN-03-3344
Published: 01 April 2004
View articletitled, Imatinib Mesylate Is a Potent Inhibitor of the ABCG2 (BCRP) Transporter and Reverses Resistance to Topotecan and SN-38 in Vitro
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Journal Articles

Replication incompetent adenoviral vectors activate the Akt/mTOR signaling pathway in rhabdomyosarcoma and IMR-90 cell lines.

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John B. Easton, Kuntebommanahalli N. Thimmaiah, Shile Huang, Franklin C. Harwood, Glen S. Germain, Peter J. Houghton
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 814.
Published: 01 April 2004
View articletitled, Replication incompetent adenoviral vectors activate the Akt/mTOR signaling pathway in rhabdomyosarcoma and IMR-90 cell lines.
Journal Articles

Insulin-like Growth Factor I-mediated Protection from Rapamycin-induced Apoptosis Is Independent of Ras-Erk1-Erk2 and Phosphatidylinositol 3′-Kinase-Akt Signaling Pathways

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Kuntebommanahalli N. Thimmaiah, John Easton, Shile Huang, Karen A. Veverka, Glen S. Germain, Franklin C. Harwood, Peter J. Houghton
Journal: Cancer Research
Cancer Res (2003) 63 (2): 364–374.
Published: 15 January 2003
View articletitled, Insulin-like Growth Factor I-mediated Protection from Rapamycin-induced Apoptosis Is Independent of Ras-Erk1-Erk2 and Phosphatidylinositol 3′-Kinase-Akt Signaling Pathways
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Journal Articles

Rapamycin Causes Poorly Reversible Inhibition of mTOR and Induces p53-independent Apoptosis in Human Rhabdomyosarcoma Cells

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Hajime Hosoi, Michael B. Dilling, Takuma Shikata, Linda N. Liu, Lili Shu, Richard A. Ashmun, Glen S. Germain, Robert T. Abraham, Peter J. Houghton
Journal: Cancer Research
Cancer Res (1999) 59 (4): 886–894.
Published: 15 February 1999
View articletitled, Rapamycin Causes Poorly Reversible Inhibition of mTOR and Induces p53-independent Apoptosis in Human Rhabdomyosarcoma Cells
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Journal Articles

Rapamycin Selectively Inhibits the Growth of Childhood Rhabdomyosarcoma Cells through Inhibition of Signaling via the Type I Insulin-like Growth Factor Receptor

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Michael B. Dilling, Peter Dias, David N. Shapiro, Glen S. Germain, Randall K. Johnson, Peter J. Houghton
Journal: Cancer Research
Cancer Res (1994) 54 (4): 903–907.
Published: 01 February 1994
View articletitled, Rapamycin Selectively Inhibits the Growth of Childhood Rhabdomyosarcoma Cells through Inhibition of Signaling via the Type I Insulin-like Growth Factor Receptor
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Journal Articles

Morphological and Molecular Characterization of Spontaneous Myogenic Differentiation in a Human Rhabdomyosarcoma Cell Line

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David N. Shapiro, Peter J. Houghton, Bonnie J. Hazelton, Glen S. Germain, Kuruganti G. Murti, Atiqur Rahman, Janet A. Houghton
Journal: Cancer Research
Cancer Res (1990) 50 (18): 6002–6009.
Published: 01 September 1990
View articletitled, Morphological and Molecular Characterization of Spontaneous Myogenic Differentiation in a Human Rhabdomyosarcoma Cell Line
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Journal Articles

N-(5-Indanylsulfonyl)-N′-(4-chlorophenyl)urea, a Novel Agent Equally Cytotoxic to Nonproliferating Human Colon Adenocarcinoma Cells

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Peter J. Houghton, Frank C. Bailey, Glen S. Germain, Gerald B. Grindey, Bryant C. Witt, Janet A. Houghton
Journal: Cancer Research
Cancer Res (1990) 50 (2): 318–322.
Published: 01 January 1990
View articletitled, N-(5-Indanylsulfonyl)-N′-(4-chlorophenyl)urea, a Novel Agent Equally Cytotoxic to Nonproliferating Human Colon Adenocarcinoma Cells
Open the PDF for N-(5-Indanylsulfonyl)-N′-(4-chlorophenyl)urea, a Novel Agent Equally Cytotoxic to Nonproliferating Human Colon Adenocarcinoma Cells in another window