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Giulio C. Spagnoli
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Journal Articles

Abstract 1001: Gut microbiota modulate T cell trafficking into human colorectal cancer

Free
Eleonora Cremonesi, Valeria Governa, Jesus Garzon, Valentina Mele, Francesca Amicarella, Manuele G. Muraro, Raoul Droeser, Martin Bolli, Julia Slotta-Huspenina, Luigi Terracciano, Paul Zajac, Giulio C. Spagnoli, Serenella Eppenberger-Castori, Klaus-Peter Janssen, Lubor Borsig, Giandomenica Iezzi
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1001.
https://doi.org/10.1158/1538-7445.AM2018-1001
Published: 01 July 2018
View articletitled, Abstract 1001: Gut microbiota modulate T cell trafficking into human colorectal cancer
Journal Articles

Abstract 2109: Prognostic and functional significance of interleukin 22 in colorectal cancer

Free
Eleonora Cremonesi, Nadia Tosti, Francesca Amicarella, Benjamin Weixler, Silvio Däster, Valeria Governa, Giulio C. Spagnoli, Luigi Terracciano, Luigi Tornillo, Serenella Eppenberger-Castori, Giandomenica Iezzi, Raoul Droeser
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2109.
https://doi.org/10.1158/1538-7445.AM2018-2109
Published: 01 July 2018
View articletitled, Abstract 2109: Prognostic and functional significance of interleukin 22 in colorectal cancer
Journal Articles

Abstract 4097: Maintenance of primary human colorectal cancer microenvironment using a perfusion bioreactor-based 3D culture system

Free
Celeste Manfredonia, Manuele Giuseppe Muraro, Christian Hirt, Valentina Mele, Valeria Governa, Adam Papadimitropoulos, Silvio Daester, Savas D. Soysal, Raoul A. Droeser, Robert Mechera, Daniel Oertli, Raffaele Rosso, Martin Bolli, Luigi M. Terracciano, Giulio C. Spagnoli, Ivan Martin, Giandomenica Iezzi
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4097.
https://doi.org/10.1158/1538-7445.AM2018-4097
Published: 01 July 2018
View articletitled, Abstract 4097: Maintenance of primary human colorectal cancer microenvironment using a perfusion bioreactor-based 3D culture system
Journal Articles

Abstract 4833: Perfusion-based bioreactor culture of primary cancer tissue maintains tumor microenvironment complexity and allow in-vitro testing of immune blockade therapy

Free
Manuele Giuseppe Muraro, Simone Muenst, Celeste Manfredonia, Valentina Mele, Silvio Daester, Alexandar Tzankov, Luigi Terracciano, Walter Weber, Giulio C. Spagnoli, Giandomenica Iezzi, Ivan Martin, Savas D. Soysal
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4833.
https://doi.org/10.1158/1538-7445.AM2017-4833
Published: 01 July 2017
View articletitled, Abstract 4833: Perfusion-based bioreactor culture of primary cancer tissue maintains tumor microenvironment complexity and allow in-vitro testing of immune blockade therapy
Journal Articles

Abstract 615: Scaffold-based perfusion bioreactor system for in vitro maintenance of primary breast cancer tissue microenvironment suitable for personalized medicine

Free
Manuele Giuseppe Muraro, Simone Muenst, Valentina Mele, Luca Quagliata, Alexandar Tzankov, Walter P. Weber, Giulio C. Spagnoli, Savas D. Soysal
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 615.
https://doi.org/10.1158/1538-7445.AM2016-615
Published: 15 July 2016
View articletitled, Abstract 615: Scaffold-based perfusion bioreactor system for in vitro maintenance of primary breast cancer tissue microenvironment suitable for personalized medicine
Journal Articles

Abstract 4031: Different expression of programmed death 1 (PD1) and its ligand (PD-L1) in esophageal and gastric cancer

Free
Silvio Däster, Serenella Eppenberger-Castori, Raoul A. Droeser, Hannah M. Schaefer, Giulio C. Spagnoli, Luigi Terracciano, Luigi Tornillo, Urs von Holzen
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4031.
https://doi.org/10.1158/1538-7445.AM2016-4031
Published: 15 July 2016
View articletitled, Abstract 4031: Different expression of programmed death 1 (PD1) and its ligand (PD-L1) in esophageal and gastric cancer
Journal Articles

Abstract 1582: Tumor-associated stromal cells increase malignancy of human colorectal cancers triggering EMT induction

Free
Valentina Mele, Valeria Governa, Manuele G. Muraro, Jesus F. Glaus Garzon, Lubor Borsig, Silvio Daester, Raoul Droeser, Daniel Oertli, Markus Zuber, Raffaele Rosso, Giulio C. Spagnoli, Giandomenica Iezzi
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1582.
https://doi.org/10.1158/1538-7445.AM2016-1582
Published: 15 July 2016
View articletitled, Abstract 1582: Tumor-associated stromal cells increase malignancy of human colorectal cancers triggering EMT induction
Journal Articles

Abstract 1275: Chemotactic factors underlying tumor infiltration by immunocompetent cells in colorectal cancer

Free
Eleonora Cremonesi, Francesca Amicarella, Elisabetta Padovan, Manuele G. Muraro, Valentina Mele, Paul Zajac, Christian Hirt, Raoul Droeser, Daniel Oertli, Markus Zuber, Michel Adamina, Raffaele Rosso, Jesus G. Garzon, Lubor Borsig, Giulio C. Spagnoli, Giandomenica Iezzi
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1275.
https://doi.org/10.1158/1538-7445.AM2015-1275
Published: 01 August 2015
View articletitled, Abstract 1275: Chemotactic factors underlying tumor infiltration by immunocompetent cells in colorectal cancer
Journal Articles

Abstract 2370: Tumor-associated stromal cells increase malignancy of human colorectal cancers triggering the induction of Epithelial-to-mesenchymal transition

Free
Valentina Mele, Manuele Giuseppe Muraro, Raoul Droeser, Daniel Oertli, Markus Zuber, Raffaele Rosso, Ivan Martin, Michael Heberer, Giulio C. Spagnoli, Giandomenica Iezzi
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2370.
https://doi.org/10.1158/1538-7445.AM2015-2370
Published: 01 August 2015
View articletitled, Abstract 2370: Tumor-associated stromal cells increase malignancy of human colorectal cancers triggering the induction of Epithelial-to-mesenchymal transition
Journal Articles

Abstract 305: An innovative 3D porous scaffold-based perfusion bioreactor system for the in vitro maintenance and expansion of primary breast cancer tissue

Free
Manuele G. Muraro, Simone Muenst, Giulio C. Spagnoli, Daniel Oertli, Walter P. Weber, Savas D. Soysal
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 305.
https://doi.org/10.1158/1538-7445.AM2015-305
Published: 01 August 2015
View articletitled, Abstract 305: An innovative 3D porous scaffold-based perfusion bioreactor system for the in vitro maintenance and expansion of primary breast cancer tissue
Journal Articles

Abstract 328: Original microenvironment of different cancer types is maintained upon culture of primary tissues in perfused bioreactors

Free
Christian Hirt, Manuele G. Muraro, Valentina Mele, Francesca Amicarella, Celeste Manfredonia, Savas D. Soysal, Simone Muenst, Luigi Mariani, Christoph Kettelhack, Michael Heberer, Giulio C. Spagnoli, Ivan Martin, Giandomenica Iezzi, Adam Papadimitropoulos
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 328.
https://doi.org/10.1158/1538-7445.AM2015-328
Published: 01 August 2015
View articletitled, Abstract 328: Original microenvironment of different cancer types is maintained upon culture of primary tissues in perfused bioreactors
Journal Articles

Abstract 4050: Association of long term NK cell culture and TIMP3 over-expression with NK cell reduced susceptibility to leukemia and epithelial cancer cell induced damage

Free
Giuseppe Sconocchia, Roberto Arriga, Sara Caratelli, Giulia Lanzilli, Andrea Coppola, Giulio C. Spagnoli, Adriano Venditti, Sergio Amadori, Davide Lauro, Maria I. Del Principe, Luca Maurillo, Francesco Buccisano, Barbara Capuani, Xinhui Wang, Soldano Ferrone
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4050.
https://doi.org/10.1158/1538-7445.AM2015-4050
Published: 01 August 2015
View articletitled, Abstract 4050: Association of long term NK cell culture and TIMP3 over-expression with NK cell reduced susceptibility to leukemia and epithelial cancer cell induced damage
Journal Articles

Abstract 1102: Neutrophils impact on growth and mobility of human colorectal cancer cells

Free
Valeria Governa, Luca Quagliata, Valentina Mele, Christian Hirt, Luigi Terracciano, Giulio C. Spagnoli, Elisabetta Padovan
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1102.
https://doi.org/10.1158/1538-7445.AM2014-1102
Published: 01 October 2014
View articletitled, Abstract 1102: Neutrophils impact on growth and mobility of human colorectal cancer cells
Journal Articles

Abstract 2029: Insight of 3D multicellular tumor spheroids for innovative culture models of potential relevance for the screening of anti-CRC compounds

Free
Silvio Däster, Nunzia Amatruda, Diego Calabrese, Paul Zajac, Giulio C. Spagnoli, Giandomenica Iezzi, Valentina Mele, Manuele Giuseppe Muraro
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2029.
https://doi.org/10.1158/1538-7445.AM2014-2029
Published: 01 October 2014
View articletitled, Abstract 2029: Insight of 3D multicellular tumor spheroids for innovative culture models of potential relevance for the screening of anti-CRC compounds
Journal Articles

Abstract 4715: OX40 expression improves the prognostic value of CD8 positive lymphocyte density in colorectal carcinoma

Free
Benjamin Weixler, Raoul A. Droeser, Roberto Sorge, Tarik Delko, Christian A. Nebiker, Giandomenica Iezzi, Giulio C. Spagnoli, Christoph Kettelhack, Urs W. von Holzen, Daniel Oertli, Luigi Terracciano, Luigi Tornillo, Giuseppe Sconocchia
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4715.
https://doi.org/10.1158/1538-7445.AM2014-4715
Published: 01 October 2014
View articletitled, Abstract 4715: OX40 expression improves the prognostic value of CD8 positive lymphocyte density in colorectal carcinoma
Journal Articles

Melanoma Cells Inhibit NK Cell Functions—Letter

Available to Purchase
Giuseppe Sconocchia, Roberto Arriga, Luigi Tornillo, Luigi Terracciano, Soldano Ferrone, Giulio C. Spagnoli
Journal: Cancer Research
Cancer Res (2012) 72 (20): 5428–5429.
https://doi.org/10.1158/0008-5472.CAN-12-1181
Published: 14 October 2012
View articletitled, Melanoma Cells Inhibit NK Cell Functions—Letter
Open the PDF for Melanoma Cells Inhibit NK Cell Functions—Letter in another window
Journal Articles

Abstract 556: L-Tag-driven systemic immune regulatory profile as a potential signature for polyomavirus BK involvement in prostate cancer

Free
Giovanni Sais, Stephen Wyler, Tvrtko Hudolin, Irina Banzola, Chantal Mengus, Lukas Bubendorf, Hans H. Hirsch, Giulio C. Spagnoli, Tullio Sulser, Maurizio Provenzano
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 556.
https://doi.org/10.1158/1538-7445.AM2012-556
Published: 15 April 2012
View articletitled, Abstract 556: L-Tag-driven systemic immune regulatory profile as a potential signature for polyomavirus BK involvement in prostate cancer
Journal Articles

Abstract 3384: High ALDH activity is associated with high tumorigenicity in prostate cancer

Free
Clémentine Le Magnen, Cyrill Rentsch, Alexander Bachmann, Stephen Wyler, Michael Heberer, Giulio C. Spagnoli, Chantal Mengus
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3384.
https://doi.org/10.1158/1538-7445.AM2012-3384
Published: 15 April 2012
View articletitled, Abstract 3384: High ALDH activity is associated with high tumorigenicity in prostate cancer
Journal Articles

Abstract 3658: The expression of genes encoding common gamma-chain cytokines is associated with tissue infiltration by CD8+ T cells displaying an “exhausted” phenotype in benign prostatic hyperplasia and prostate cancer

Free
Chantal Mengus, Clémentine Le Magnen, Lukas Bubendorf, Alexander Bachmann, Michael Heberer, Giulio C. Spagnoli, Stephen Wyler
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3658.
https://doi.org/10.1158/1538-7445.AM2011-3658
Published: 15 April 2011
View articletitled, Abstract 3658: The expression of genes encoding common gamma-chain cytokines is associated with tissue infiltration by CD8+ T cells displaying an “exhausted” phenotype in benign prostatic hyperplasia and prostate cancer
Journal Articles

Abstract 1500: Modulation of recombinant vaccinia virus vector immunogenicity

Free
Nermin Raafat, Chantal Mengus, Michael Heberer, Giulio C. Spagnoli, Paul Zajac
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1500.
https://doi.org/10.1158/1538-7445.AM10-1500
Published: 15 April 2010
View articletitled, Abstract 1500: Modulation of recombinant vaccinia virus vector immunogenicity