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Gisele Nishiguchi
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Journal Articles

Abstract 481: Investigating molecular glues as a new therapeutic approach to high-risk neuroblastoma

Ian Delahunty, Gisele Nishiguchi, Yang Zhang, Abigail Fish, Anand Mayasundari, Jun Qi, Brian Abraham, Anang Shelat, Zoran Rankovic, Adam Durbin
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 481.
https://doi.org/10.1158/1538-7445.AM2023-481
Published: 04 April 2023
View article titled, Abstract 481: Investigating molecular glues as a new therapeutic approach to high-risk neuroblastoma
Journal Articles

Abstract 2808: Simultaneous inhibition of SHP2 phosphatase at two allosteric sites

Michelle Fodor, Edmund Price, Ping Wang, Hengyu Lu, Andreea Argintaru, Zhouliang Chen, Meir Glick, Huai-Xiang Hao, Mitsunori Kato, Robert Koenig, Jonathan R. LaRochelle, Gang Liu, Eric McNeill, Dyuti Majumdar, Gisele Nishiguchi, Lawrence Perez, Greg Paris, Christopher Quinn, Timothy Ramsey, Martin Sendzik, Michael Shultz, Sarah Williams, Travis Stams, Stephen C. Blacklow, Matthew J. LaMarche, Michael G. Acker
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2808.
https://doi.org/10.1158/1538-7445.AM2018-2808
Published: 01 July 2018
View article titled, Abstract 2808: Simultaneous inhibition of SHP2 phosphatase at two allosteric sites
Journal Articles

Antitumor Properties of RAF709, a Highly Selective and Potent Inhibitor of RAF Kinase Dimers, in Tumors Driven by Mutant RAS or BRAF

Wenlin Shao, Yuji M. Mishina, Yun Feng, Giordano Caponigro, Vesselina G. Cooke, Stacy Rivera, Yingyun Wang, Fang Shen, Joshua M. Korn, Lesley A. Mathews Griner, Gisele Nishiguchi, Alice Rico, John Tellew, Jacob R. Haling, Robert Aversa, Valery Polyakov, Richard Zang, Mohammad Hekmat-Nejad, Payman Amiri, Mallika Singh, Nicholas Keen, Michael P. Dillon, Emma Lees, Savithri Ramurthy, William R. Sellers, Darrin D. Stuart
Journal: Cancer Research
Cancer Res (2018) 78 (6): 1537–1548.
https://doi.org/10.1158/0008-5472.CAN-17-2033
Published: 14 March 2018
View article titled, Antitumor Properties of RAF709, a Highly Selective and Potent Inhibitor of RAF Kinase Dimers, in Tumors Driven by Mutant RAS or BRAF
Open the PDF for Antitumor Properties of RAF709, a Highly Selective and Potent Inhibitor of RAF Kinase Dimers, in Tumors Driven by Mutant RAS or BRAF in another window
Includes: Supplementary data
Journal Articles

Abstract 330: Development of a highly selective B/CRAF kinase inhibitor that exhibits antitumor activities in RAS and BRAF mutant tumors with minimal paradoxical activation

Wenlin Shao, Yuji Mishina, Yun Feng, Giordano Caponigro, Savithri Ramurthy, Vesselina Cooke, Lesley Griner, Gisele Nishiguchi, Alice Rico, Ben Taft, Matthew Burger, Huw Tanner, Valery Polyakov, Brent Appleton, John Tellew, Richard Zang, Mohammad Hekmat-Nejad, Payman Amiri, Mallika Singh, Darrin Stuart
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 330.
https://doi.org/10.1158/1538-7445.AM2016-330
Published: 15 July 2016
View article titled, Abstract 330: Development of a highly selective B/CRAF kinase inhibitor that exhibits antitumor activities in RAS and BRAF mutant tumors with minimal paradoxical activation