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Giovanni Scambia
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Journal Articles

Abstract PO2-01-14: Development of Artificial Intelligence-based Machine Learning Models for Predicting Survival In Hormone-Receptor-Positive/HER2-Negative Early Breast Cancer undergoing Neoadjuvant Chemotherapy

Free
Luca Mastrantoni, Giovanna Garufi, Noemi Maliziola, Elena Di Monte, Giorgia Arcuri, Valentina Frescura, Angelachiara Rotondi, Giulia Giordano, Luisa Carbognin, Alessandra Fabi, Ida Paris, Gianluca Franceschini, Armando Orlandi, Antonella Palazzo, Giovanni Scambia, Giampaolo Tortora, Emilio Bria
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO2-01-14.
https://doi.org/10.1158/1538-7445.SABCS23-PO2-01-14
Published: 02 May 2024
View article titled, Abstract PO2-01-14: Development of Artificial Intelligence-based Machine Learning Models for Predicting Survival In Hormone-Receptor-Positive/HER2-Negative Early Breast Cancer undergoing Neoadjuvant Chemotherapy
Journal Articles

Abstract PO5-08-02: Endocrine Disruptors and Life STILe in Patients Carrying BRCA Pathogenic VAriants With Breast and/or Ovarian CAncer and Women Without Neoplasm: the STILVARCA study

Free
Antonio Franco, Alessandro Rossi, Daniela Andreina Terribile, Emanuela Lucci Cordisco, Ida Paris, Margherita Muratore, Elena Florio, Vanda Salutari, Francesco Pavese, Federica Francesca L'Erario, Antonella Palazzo, Enrico Di Guglielmo, Giulia Borghesiani, Ludovica Cardinali, Elisabetta Ferretti, Giovanni Terrana, Diana Giannarelli, Giovanni Scambia, Silvia Migliaccio, Alessandra Fabi
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO5-08-02.
https://doi.org/10.1158/1538-7445.SABCS23-PO5-08-02
Published: 02 May 2024
View article titled, Abstract PO5-08-02: Endocrine Disruptors and Life STILe in Patients Carrying BRCA Pathogenic VAriants With Breast and/or Ovarian CAncer and Women Without Neoplasm: the STILVARCA study
Journal Articles

Abstract PO4-01-02: High throughput analysis in HER2 positive locally advanced breast cancer: pCR and mutational status

Free
Ida Paris, Angelo Minucci, Daniele Generali, simona Nanni, Tatiana D'angelo, Francesco Pavese, Alessandra Fabi, Maria De Bonis, Katia Cannita, Alessia Piermattei, Giordana Tiberi, Paola Fuso, Luisa Carbognin, Silvia Rotondaro, Camilla Nero, Flavia Giacomini, Tina Pasciuto, Maria Marrazzo, Luciano Giaco', Antonino Mulè, Riccardo Masetti, Gianluca Franceschini, Giorgia Garganese, Diana Giannarelli, Giovanni Scambia
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO4-01-02.
https://doi.org/10.1158/1538-7445.SABCS23-PO4-01-02
Published: 02 May 2024
View article titled, Abstract PO4-01-02: High throughput analysis in HER2 positive locally advanced breast cancer: pCR and mutational status
Journal Articles

Abstract 3793: Mutational and gene expression profiles of the primary tumor and matched brain metastasis of epithelial ovarian cancer reveal differences in LAMC3 and MYC target genes

Free
Rita Trozzi, Camilla Nero, Marianna Buttarelli, Marcello Salvi, Luciano Giacò, Angelo Minucci, Claudia Marchetti, Carolina Sassu, Federica Persiani, Lorenzo De Marco, Simona Duranti, Camarda Floriana, Valentina Iacobelli, Ilenia Marino, Luca Mastrantoni, Flavia Giacomini, Alessia Piermattei, Mariagrazia Valentini, Tina Pasciuto, De Bonis Maria, Giuseppina Raspaglio, Diana Giannarelli, Anna Fagotti, Davide Cacchiarelli, Giovanni Scambia
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3793.
https://doi.org/10.1158/1538-7445.AM2024-3793
Published: 22 March 2024
View article titled, Abstract 3793: Mutational and gene expression profiles of the primary tumor and matched brain metastasis of epithelial ovarian cancer reveal differences in LAMC3 and MYC target genes
Journal Articles

Abstract 980: Plasma tumor fraction is an independent prognostic marker of response to front line chemotherapy in high-grade serous epithelial ovarian cancer: The MITO-16a/MANGO-OV2a/clinical trial experience

Free
Sergio Marchini, Lara Paracchini, Laura Arenare, Giovanni Scambia, Carmela Pisano, Riccardo Zadro, Laura Mannarino, Annamaria Ferrero, Paolo Chiodini, Daniela Califano, Sandro Pignata, Maurizio D'Incalci
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 980.
https://doi.org/10.1158/1538-7445.AM2024-980
Published: 22 March 2024
View article titled, Abstract 980: Plasma tumor fraction is an independent prognostic marker of response to front line chemotherapy in high-grade serous epithelial ovarian cancer: The MITO-16a/MANGO-OV2a/clinical trial experience
Journal Articles

Abstract 3647: Digital spatial transcriptomic reveals different epithelial and immune cells signatures across endometriosis-related diseases: From simple ovarian endometriosis to ovarian cancer

Free
Valentina Iacobelli, Camilla Nero, Stefano Alivernini, Giulia Scaglione, Floriana Camarda, Francesca Sillano, Rita Trozzi, Alessia Piermattei, Barbara Tolusso, Giulia Mantini, Luciano Giacò, Gloria Anderson, Gian Franco Zannoni, Elisa Gremese, Anna Fagotti, Giovanni Scambia
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3647.
https://doi.org/10.1158/1538-7445.AM2024-3647
Published: 22 March 2024
View article titled, Abstract 3647: Digital spatial transcriptomic reveals different epithelial and immune cells signatures across endometriosis-related diseases: From simple ovarian endometriosis to ovarian cancer
Journal Articles

Abstract A062: Untargeted analysis of plasma tumor fraction is an independent prognostic marker of response to front line chemotherapy in high-grade serous epithelial ovarian cancer: the MITO-16A/MANGO-OV2A clinical trial experience

Free
Sergio Marchini, Lara Paracchini, Laura Arenare, Giovanni Scambia, Carmela Pisano, Riccardo Zadro, Laura Mannarino, Annamaria Ferrero, Paolo Chiodini, Daniela Califano, Piergiacomo Di Gennaro, Sandro Pignata, Maurizio D'Incalci
Journal: Cancer Research
Cancer Res (2024) 84 (5_Supplement_2): A062.
https://doi.org/10.1158/1538-7445.OVARIAN23-A062
Published: 04 March 2024
View article titled, Abstract A062: Untargeted analysis of plasma tumor fraction is an independent prognostic marker of response to front line chemotherapy in high-grade serous epithelial ovarian cancer: the MITO-16A/MANGO-OV2A clinical trial experience
Journal Articles

Abstract A078: In vivo tumor micro-environment characterization: preliminary results of an ovarian cancer patients-derived co-colture organoids platform

Free
Floriana Camarda, Clara Di Mario, Camilla Nero, Barbara Tolusso, Stefano Alivernini, Francesca Sillano, Sonia Mastrogiovanni, Tina Pasciuto, Elisa Gremese, Eleonora Cesari, Alessandra Ciucci, Claudio Sette, Giovanni Scambia
Journal: Cancer Research
Cancer Res (2024) 84 (5_Supplement_2): A078.
https://doi.org/10.1158/1538-7445.OVARIAN23-A078
Published: 04 March 2024
View article titled, Abstract A078: In vivo tumor micro-environment characterization: preliminary results of an ovarian cancer patients-derived co-colture organoids platform
Journal Articles

Abstract A092: Ovarian tumor organotypic slices cultures for functional drug screening (TOSCA)

Free
Rita Trozzi, Camilla Nero, Marianna Buttarelli, Francesca Sillano, Cristian Ripoli, Raimondo Sollazzo, Giada Bianchetti, Donatella Lucchetti, Alessandro Sgambato, Claudio Grassi, Marco De Spirito, Giovanni Scambia
Journal: Cancer Research
Cancer Res (2024) 84 (5_Supplement_2): A092.
https://doi.org/10.1158/1538-7445.OVARIAN23-A092
Published: 04 March 2024
View article titled, Abstract A092: Ovarian tumor organotypic slices cultures for functional drug screening (TOSCA)
Journal Articles

Abstract P3-05-06: Impact on outcome and response to neoadiuvant chemotherapy in triple negative breast cancer patients and BRCA mutations

Free
Ida Paris, Roberta Rizza, Carmela Paolillo, Luisa Carbognin, Alessandra Calegari, Giovanni Scambia, Emilio Bria, Ettore Capoluongo, Riccardo Masetti, Andrea Urbani, Mariangela Pasqualoni, Concetta Santonocito
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P3-05-06.
https://doi.org/10.1158/1538-7445.SABCS19-P3-05-06
Published: 15 February 2020
View article titled, Abstract P3-05-06: Impact on outcome and response to neoadiuvant chemotherapy in triple negative breast cancer patients and BRCA mutations
Journal Articles

Abstract 3994: Herpes virus microRNA expression and significance in serous ovarian cancer

Free
Deep Pandya, Marisa Mariani, Mark McHugh, Mirko Andreoli, Steven Sieber, Shiquan He, Candice Dowell-Martino, Paul Fiedler, Giovanni Scambia, Cristiano Ferlini
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3994.
https://doi.org/10.1158/1538-7445.AM2015-3994
Published: 01 August 2015
View article titled, Abstract 3994: Herpes virus microRNA expression and significance in serous ovarian cancer
Journal Articles

Abstract 4327: Nek6 and Hif-1α cooperate with the cytoskeletal gateway of drug resistance to drive outcome in serous ovarian cancer

Free
Marta De Donato, Mara Fanelli, Marisa Mariani, Giuseppina Raspaglio, Deep Pandya, Shiquan He, Paul Fiedler, Marco Petrillo, Giovanni Scambia, Cristiano Ferlini
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4327.
https://doi.org/10.1158/1538-7445.AM2015-4327
Published: 01 August 2015
View article titled, Abstract 4327: Nek6 and Hif-1α cooperate with the cytoskeletal gateway of drug resistance to drive outcome in serous ovarian cancer
Journal Articles

Abstract 3725: HGF/c-Met axis drives cancer aggressiveness in the neo-adjuvant setting of ovarian cancer

Free
Marisa Mariani, Mark McHugh, Marco Petrillo, Steven Sieber, Shiquan He, Mirko Andreoli, Paul Fiedler, Giovanni Scambia, Shohreh Shahabi, Cristiano Ferlini
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3725.
https://doi.org/10.1158/1538-7445.AM2014-3725
Published: 01 October 2014
View article titled, Abstract 3725: HGF/c-Met axis drives cancer aggressiveness in the neo-adjuvant setting of ovarian cancer
Journal Articles

Abstract 1957: MiR-200c can mediate either poor or good outcome in ovarian cancer depending on HuR localization in the cell.

Free
Silvia Prislei, Enrica Martinelli, Marisa Mariani, Giuseppina Raspaglio, Steven Sieber, Gabriella Ferrandina, Shohreh Shahabi, Giovanni Scambia, Cristiano Ferlini
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1957.
https://doi.org/10.1158/1538-7445.AM2013-1957
Published: 15 April 2013
View article titled, Abstract 1957: MiR-200c can mediate either poor or good outcome in ovarian cancer depending on HuR localization in the cell.
Journal Articles

Abstract 4522: Androgen receptor is a main driver of aggressiveness in colorectal cancer through the class III β-tubulin pathway

Free
Marisa Mariani, Gian Franco Zannoni, Stefano Sioletic, Steven Sieber, Candice Martino, Enrica Martinelli, Claudio Coco, Giovanni Scambia, Shohreh Shahabi, Cristiano Ferlini
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4522.
https://doi.org/10.1158/1538-7445.AM2012-4522
Published: 15 April 2012
View article titled, Abstract 4522: Androgen receptor is a main driver of aggressiveness in colorectal cancer through the class III β-tubulin pathway
Journal Articles

Abstract 4055: Class III β-tubulin and the cytoskeletal gateway of drug resistance in ovarian cancer

Free
Marisa Mariani, Marta De Donato, Lella Petrella, Enrica Martinelli, Gabriella Ferrandina, Gian Franco Zannoni, Giovanni Scambia, Shohreh Shahabi, Cristiano Ferlini
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4055.
https://doi.org/10.1158/1538-7445.AM2011-4055
Published: 15 April 2011
View article titled, Abstract 4055: Class III β-tubulin and the cytoskeletal gateway of drug resistance in ovarian cancer
Journal Articles

HuR Regulates β-Tubulin Isotype Expression in Ovarian Cancer

Free
Giuseppina Raspaglio, Ilaria De Maria, Flavia Filippetti, Enrica Martinelli, Gian Franco Zannoni, Silvia Prislei, Gabriella Ferrandina, Shohreh Shahabi, Giovanni Scambia, Cristiano Ferlini
Journal: Cancer Research
Cancer Res (2010) 70 (14): 5891–5900.
https://doi.org/10.1158/0008-5472.CAN-09-4656
Published: 14 July 2010
View article titled, HuR Regulates β-Tubulin Isotype Expression in Ovarian Cancer
Open the PDF for HuR Regulates β-Tubulin Isotype Expression in Ovarian Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 645: Class V β-tubulin expression as biomarker in solid tumors

Free
Cristiano Ferlini, Marisa Mariani, Enrica Martinelli, Ilaria De Maria, Gian Franco Zannoni, Gabriella Ferrandina, Giovanni Scambia
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 645.
https://doi.org/10.1158/1538-7445.AM10-645
Published: 15 April 2010
View article titled, Abstract 645: Class V β-tubulin expression as biomarker in solid tumors
Journal Articles

Paclitaxel Directly Binds to Bcl-2 and Functionally Mimics Activity of Nur77

Free
Cristiano Ferlini, Lucia Cicchillitti, Giuseppina Raspaglio, Silvia Bartollino, Samanta Cimitan, Carlo Bertucci, Simona Mozzetti, Daniela Gallo, Marco Persico, Caterina Fattorusso, Giuseppe Campiani, Giovanni Scambia
Journal: Cancer Research
Cancer Res (2009) 69 (17): 6906–6914.
https://doi.org/10.1158/0008-5472.CAN-09-0540
Published: 31 August 2009
View article titled, Paclitaxel Directly Binds to Bcl-2 and Functionally Mimics Activity of Nur77
Open the PDF for Paclitaxel Directly Binds to Bcl-2 and Functionally Mimics Activity of Nur77 in another window
Includes: Supplementary data
Journal Articles

Abstract #3877: Class III \#946; -tubulin expression is stimulated by hypoglycemia through a pathway mediated by ELAVL1

Free
Giuseppina Raspaglio, Ilaria De Maria, Flavia Filippetti, Giovanni Scambia, Cristiano Ferlini
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3877.
Published: 01 May 2009
View article titled, Abstract #3877: Class III \#946; -tubulin expression is stimulated by hypoglycemia through a pathway mediated by ELAVL1