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Giorgio Stassi
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Journal Articles

IL4 Primes the Dynamics of Breast Cancer Progression via DUSP4 Inhibition

Miriam Gaggianesi, Alice Turdo, Aurora Chinnici, Elisa Lipari, Tiziana Apuzzo, Antonina Benfante, Isabella Sperduti, Simone Di Franco, Serena Meraviglia, Elena Lo Presti, Francesco Dieli, Valentina Caputo, Gabriella Militello, Salvatore Vieni, Giorgio Stassi, Matilde Todaro
Journal: Cancer Research
Cancer Res (2017) 77 (12): 3268–3279.
https://doi.org/10.1158/0008-5472.CAN-16-3126
Published: 14 June 2017
View article titled, IL4 Primes the Dynamics of Breast Cancer Progression via DUSP4 Inhibition
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Includes: Supplementary data
Journal Articles

Abstract 3311: Autocrine and paracrine IL-4 maintains breast cancer stem cells traits via RAS/MAPK/DUSP pathway

Alice Turdo, Miriam Gaggianesi, Tiziana Apuzzo, Antonina Benfante, Aurora Chinnici, Alessandro Giammona, Simone Di Franco, Giorgio Stassi, Matilde Todaro
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3311.
https://doi.org/10.1158/1538-7445.AM2016-3311
Published: 15 July 2016
View article titled, Abstract 3311: Autocrine and paracrine IL-4 maintains breast cancer stem cells traits via RAS/MAPK/DUSP pathway
Journal Articles

Abstract 2484: Non-canonical Hedgehog/Gli1 signaling drives lung adenocarcinoma stem cells survival and its targeting inhibits CSC-derived tumors

Agnese Po, Marianna Silvano, Evelina Miele, Adriana Eramo, Matilde Todaro, Carlo Capalbo, Valentina Salvati, Giovanni Sette, Danilo Cucchi, Zein M. Besharat, Gianluca Canettieri, Lucia Di Marcotullio, Isabella Screpanti, Giorgio Stassi, Ruggero De Maria, Ann Zeuner, Enrico De Smaele, Elisabetta Ferretti
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2484.
https://doi.org/10.1158/1538-7445.AM2016-2484
Published: 15 July 2016
View article titled, Abstract 2484: Non-canonical Hedgehog/Gli1 signaling drives lung adenocarcinoma stem cells survival and its targeting inhibits CSC-derived tumors
Journal Articles

Abstract 3193: Development of a colon cancer model system reveals epithelial contribution to poor-prognosis gene signatures

Pramudita R. Prasetyanti, Sander R. van Hooff, Hans M. Rodermond, Tessa van Herwaarden, Kieshen Kalloe, Nathalie R. de Vries, Ronals van Leersum, Joan H. de jong, Evelyn Fessler, Nicolo Baldi, Giorgio Stassi, Jan Paul Medema
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3193.
https://doi.org/10.1158/1538-7445.AM2016-3193
Published: 15 July 2016
View article titled, Abstract 3193: Development of a colon cancer model system reveals epithelial contribution to poor-prognosis gene signatures
Journal Articles

Activated Thyroid Hormone Promotes Differentiation and Chemotherapeutic Sensitization of Colorectal Cancer Stem Cells by Regulating Wnt and BMP4 Signaling

Veronica Catalano, Monica Dentice, Raffaele Ambrosio, Cristina Luongo, Rosachiara Carollo, Antonina Benfante, Matilde Todaro, Giorgio Stassi, Domenico Salvatore
Journal: Cancer Research
Cancer Res (2016) 76 (5): 1237–1244.
https://doi.org/10.1158/0008-5472.CAN-15-1542
Published: 29 February 2016
View article titled, Activated Thyroid Hormone Promotes Differentiation and Chemotherapeutic Sensitization of Colorectal Cancer Stem Cells by Regulating Wnt and BMP4 Signaling
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Includes: Supplementary data
Journal Articles

Abstract LB-143: DNp63 governs metastatic outgrowth of breast cancer stem cells

Alice Turdo, Simone Di Franco, Antonina Benfante, Maria Luisa Colorito, Marco Bonanno, Miriam Gaggianesi, Daniela Barcaroli, Francesco Dieli, Jan Paul Medema, Vincenzo De Laurenzi, Giorgio Stassi, Matilde Todaro
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): LB-143.
https://doi.org/10.1158/1538-7445.AM2015-LB-143
Published: 01 August 2015
View article titled, Abstract LB-143: DNp63 governs metastatic outgrowth of breast cancer stem cells
Journal Articles

Abstract 3897: Sam68 sustains self-renewal and invasiveness of breast cancer initiating cells

Alice Turdo, Miriam Gaggianesi, Antonina Benfante, Mauro Piantelli, Matilde Todaro, Giorgio Stassi
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3897.
https://doi.org/10.1158/1538-7445.AM2014-3897
Published: 01 October 2014
View article titled, Abstract 3897: Sam68 sustains self-renewal and invasiveness of breast cancer initiating cells
Journal Articles

Erythropoietin Activates Cell Survival Pathways in Breast Cancer Stem–like Cells to Protect Them from Chemotherapy

Matilde Todaro, Alice Turdo, Monica Bartucci, Flora Iovino, Rosanna Dattilo, Marco Biffoni, Giorgio Stassi, Giulia Federici, Ruggero De Maria, Ann Zeuner
Journal: Cancer Research
Cancer Res (2013) 73 (21): 6393–6400.
https://doi.org/10.1158/0008-5472.CAN-13-0248
Published: 31 October 2013
View article titled, Erythropoietin Activates Cell Survival Pathways in Breast Cancer Stem–like Cells to Protect Them from Chemotherapy
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Journal Articles

Tumorigenic and Metastatic Activity of Human Thyroid Cancer Stem Cells

Matilde Todaro, Flora Iovino, Vincenzo Eterno, Patrizia Cammareri, Guido Gambara, Virginia Espina, Gaspare Gulotta, Francesco Dieli, Silvia Giordano, Ruggero De Maria, Giorgio Stassi
Journal: Cancer Research
Cancer Res (2010) 70 (21): 8874–8885.
https://doi.org/10.1158/0008-5472.CAN-10-1994
Published: 31 October 2010
View article titled, Tumorigenic and Metastatic Activity of Human Thyroid Cancer Stem Cells
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Includes: Supplementary data
Journal Articles

Aurora-A Is Essential for the Tumorigenic Capacity and Chemoresistance of Colorectal Cancer Stem Cells

Patrizia Cammareri, Alessandro Scopelliti, Matilde Todaro, Vincenzo Eterno, Federica Francescangeli, Mary Pat Moyer, Antonino Agrusa, Francesco Dieli, Ann Zeuner, Giorgio Stassi
Journal: Cancer Research
Cancer Res (2010) 70 (11): 4655–4665.
https://doi.org/10.1158/0008-5472.CAN-09-3953
Published: 01 June 2010
View article titled, Aurora-A Is Essential for the Tumorigenic Capacity and Chemoresistance of Colorectal Cancer Stem Cells
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Includes: Supplementary data
Journal Articles

The AC133 Epitope, but not the CD133 Protein, Is Lost upon Cancer Stem Cell Differentiation

Kristel Kemper, Martin R. Sprick, Martijn de Bree, Alessandro Scopelliti, Louis Vermeulen, Maarten Hoek, Jurrit Zeilstra, Steven T. Pals, Huseyin Mehmet, Giorgio Stassi, Jan Paul Medema
Journal: Cancer Research
Cancer Res (2010) 70 (2): 719–729.
https://doi.org/10.1158/0008-5472.CAN-09-1820
Published: 13 January 2010
View article titled, The AC133 Epitope, but not the CD133 Protein, Is Lost upon Cancer Stem Cell Differentiation
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Includes: Supplementary data
Journal Articles

Suppressor of Cytokine Signaling 3 Sensitizes Anaplastic Thyroid Cancer to Standard Chemotherapy

Maria Giovanna Francipane, Vincenzo Eterno, Valentina Spina, Miriam Bini, Gregorio Scerrino, Giuseppe Buscemi, Gaspare Gulotta, Matilde Todaro, Francesco Dieli, Ruggero De Maria, Giorgio Stassi
Journal: Cancer Research
Cancer Res (2009) 69 (15): 6141–6148.
https://doi.org/10.1158/0008-5472.CAN-09-0994
Published: 29 July 2009
View article titled, Suppressor of Cytokine Signaling 3 Sensitizes Anaplastic Thyroid Cancer to Standard Chemotherapy
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Journal Articles

Breast Cancer Cell Lines Contain Functional Cancer Stem Cells with Metastatic Capacity and a Distinct Molecular Signature

Emmanuelle Charafe-Jauffret, Christophe Ginestier, Flora Iovino, Julien Wicinski, Nathalie Cervera, Pascal Finetti, Min-Hee Hur, Mark E. Diebel, Florence Monville, Julie Dutcher, Marty Brown, Patrice Viens, Luc Xerri, François Bertucci, Giorgio Stassi, Gabriela Dontu, Daniel Birnbaum, Max S. Wicha
Journal: Cancer Research
Cancer Res (2009) 69 (4): 1302–1313.
https://doi.org/10.1158/0008-5472.CAN-08-2741
Published: 12 February 2009
View article titled, Breast Cancer Cell Lines Contain Functional Cancer Stem Cells with Metastatic Capacity and a Distinct Molecular Signature
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Includes: Supplementary data
Journal Articles

Crucial Role of Interleukin-4 in the Survival of Colon Cancer Stem Cells

Maria Giovanna Francipane, Mileidys Perez Alea, Ylenia Lombardo, Matilde Todaro, J.P. Medema, Giorgio Stassi
Journal: Cancer Research
Cancer Res (2008) 68 (11): 4022–4025.
https://doi.org/10.1158/0008-5472.CAN-07-6874
Published: 02 June 2008
View article titled, Crucial Role of Interleukin-4 in the Survival of Colon Cancer Stem Cells
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Journal Articles

MUC1 Oncoprotein Promotes Refractoriness to Chemotherapy in Thyroid Cancer Cells

Mauro Siragusa, Monica Zerilli, Flora Iovino, Maria Giovanna Francipane, Ylenia Lombardo, Lucia Ricci-Vitiani, Giuseppe Di Gesù, Matilde Todaro, Ruggero De Maria, Giorgio Stassi
Journal: Cancer Research
Cancer Res (2007) 67 (11): 5522–5530.
https://doi.org/10.1158/0008-5472.CAN-06-4197
Published: 01 June 2007
View article titled, MUC1 Oncoprotein Promotes Refractoriness to Chemotherapy in Thyroid Cancer Cells
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Journal Articles

Altered Expression of c-IAP1, Survivin, and Smac Contributes to Chemotherapy Resistance in Thyroid Cancer Cells

Elena Tirrò, Maria Letizia Consoli, Michele Massimino, Livia Manzella, Francesco Frasca, Laura Sciacca, Luisa Vicari, Giorgio Stassi, Luigi Messina, Angelo Messina, Paolo Vigneri
Journal: Cancer Research
Cancer Res (2006) 66 (8): 4263–4272.
https://doi.org/10.1158/0008-5472.CAN-05-3248
Published: 17 April 2006
View article titled, Altered Expression of c-IAP1, Survivin, and Smac Contributes to Chemotherapy Resistance in Thyroid Cancer Cells
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Journal Articles

Autocrine Production of Interleukin-4 and Interleukin-10 Is Required for Survival and Growth of Thyroid Cancer Cells

Matilde Todaro, Monica Zerilli, Lucia Ricci-Vitiani, Miriam Bini, Mileidys Perez Alea, Ada Maria Florena, Laura Miceli, Gerolama Condorelli, Sebastiano Bonventre, Giuseppe Di Gesù, Ruggero De Maria, Giorgio Stassi
Journal: Cancer Research
Cancer Res (2006) 66 (3): 1491–1499.
https://doi.org/10.1158/0008-5472.CAN-05-2514
Published: 01 February 2006
View article titled, Autocrine Production of Interleukin-4 and Interleukin-10 Is Required for Survival and Growth of Thyroid Cancer Cells
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Journal Articles

Inhibition of DNA Methylation Sensitizes Glioblastoma for Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand–Mediated Destruction

Adriana Eramo, Roberto Pallini, Fiorenza Lotti, Giovanni Sette, Mariella Patti, Monica Bartucci, Lucia Ricci-Vitiani, Michele Signore, Giorgio Stassi, Luigi M. Larocca, Lucio Crinò, Cesare Peschle, Ruggero De Maria
Journal: Cancer Research
Cancer Res (2005) 65 (24): 11469–11477.
https://doi.org/10.1158/0008-5472.CAN-05-1724
Published: 15 December 2005
View article titled, Inhibition of DNA Methylation Sensitizes Glioblastoma for Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand–Mediated Destruction
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Journal Articles

PED Mediates AKT-Dependent Chemoresistance in Human Breast Cancer Cells

Giorgio Stassi, Michela Garofalo, Monica Zerilli, Lucia Ricci-Vitiani, Ciro Zanca, Matilde Todaro, Federico Aragona, Gennaro Limite, Giuseppe Petrella, Gerolama Condorelli
Journal: Cancer Research
Cancer Res (2005) 65 (15): 6668–6675.
https://doi.org/10.1158/0008-5472.CAN-04-4009
Published: 01 August 2005
View article titled, PED Mediates AKT-Dependent Chemoresistance in Human Breast Cancer Cells
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Journal Articles

PED/PEA-15 mediates AKT dependent chemoresistance in human breast cancer cells

Giorgio Stassi, Michela Garofalo, Monica Zerilli, Lucia Ricci-Vitiani, Ciro Zanca, Matilde Todaro, Emma Sanzari, Gerolama Condorelli
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 781–782.
Published: 01 May 2005
View article titled, PED/PEA-15 mediates AKT dependent chemoresistance in human breast cancer cells