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Giorgio Milazzo
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Journal Articles

Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface

Jessica Koach, Jessica K. Holien, Hassina Massudi, Daniel R. Carter, Olivia C. Ciampa, Mika Herath, Taylor Lim, Janith A. Seneviratne, Giorgio Milazzo, Jayne E. Murray, Joshua A. McCarroll, Bing Liu, Chelsea Mayoh, Bryce Keenan, Brendan W. Stevenson, Michael A. Gorman, Jessica L. Bell, Larissa Doughty, Stefan Hüttelmaier, Andre Oberthuer, Matthias Fischer, Andrew J. Gifford, Tao Liu, Xiaoling Zhang, Shizhen Zhu, W. Clay Gustafson, Michelle Haber, Murray D. Norris, Jamie I. Fletcher, Giovanni Perini, Michael W. Parker, Belamy B. Cheung, Glenn M. Marshall
Journal: Cancer Research
Series: Author Choice
Cancer Res (2019) 79 (21): 5652–5667.
https://doi.org/10.1158/0008-5472.CAN-19-1112
Published: 01 November 2019
View articletitled, Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface
Open the PDF for Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface in another window
Includes: Supplementary data
Journal Articles

Abstract 2453: Eradication of neuroblastoma by suppressing the expression of a single noncoding RNA

Andrew E. Tee, Pei Y. Liu, Giorgio Milazzo, Kate M. Hannan, Jesper Maag, Nenad Bartonicek, Renhua Song, Chen C. Jiang, Xu D. Zhang, Murray D. Norris, Michelle Haber, Glenn M. Marshall, Jinyan Li, Jo Vandesompele, John S. Mattick, Pieter Mestdagh, Giovanni Perini, Ross D. Hannan, Marcel E. Dinger, Tao Liu
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2453.
https://doi.org/10.1158/1538-7445.AM2018-2453
Published: 01 July 2018
View articletitled, Abstract 2453: Eradication of neuroblastoma by suppressing the expression of a single noncoding RNA
Journal Articles

Abstract LB-080: The histone methyltransferase DOT1L promotes neuroblastoma by regulating gene transcription

Matthew Wong, Andrew Tee, Giorgio Milazzo, Jessica Bell, Stefan Hüttelmaier, Patsie Polly, Giovanni Perini, Christopher J. Scarlett, Tao Liu
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): LB-080.
https://doi.org/10.1158/1538-7445.AM2017-LB-080
Published: 01 July 2017
View articletitled, Abstract LB-080: The histone methyltransferase DOT1L promotes neuroblastoma by regulating gene transcription
Journal Articles

The Histone Methyltransferase DOT1L Promotes Neuroblastoma by Regulating Gene Transcription

Matthew Wong, Andrew E.L. Tee, Giorgio Milazzo, Jessica L. Bell, Rebecca C. Poulos, Bernard Atmadibrata, Yuting Sun, Duohui Jing, Nicholas Ho, Dora Ling, Pei Yan Liu, Xu Dong Zhang, Stefan Hüttelmaier, Jason W.H. Wong, Jenny Wang, Patsie Polly, Giovanni Perini, Christopher J. Scarlett, Tao Liu
Journal: Cancer Research
Cancer Res (2017) 77 (9): 2522–2533.
https://doi.org/10.1158/0008-5472.CAN-16-1663
Published: 30 April 2017
View articletitled, The Histone Methyltransferase DOT1L Promotes Neuroblastoma by Regulating Gene Transcription
Open the PDF for The Histone Methyltransferase DOT1L Promotes Neuroblastoma by Regulating Gene Transcription in another window
Includes: Supplementary data
Journal Articles

Abstract 2664: Eradication of neuroblastoma by suppressing the expression of a single long noncoding RNA

Andrew E. Tee, Pei Y. Liu, Giorgio Milazzo, Jo Vandesompele, Glenn M. Marshall, Giovanni Perini, Pieter Mestdagh, Marcel Dinger, Tao Liu
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2664.
https://doi.org/10.1158/1538-7445.AM2016-2664
Published: 15 July 2016
View articletitled, Abstract 2664: Eradication of neuroblastoma by suppressing the expression of a single long noncoding RNA
Journal Articles

Abstract 2450: MYCN and TFAP4 promote neuroblastoma malignancy by cooperating in the regulation a subset of target genes involved in cancer cell growth and metastasis

Chengyuan Xue, Denise M. Yu, Samuele Gherardi, Jessica Koach, Giorgio Milazzo, Laura Gamble, Bing Liu, Amanda Russell, Tao Liu, Belamy B. Cheung, Glenn M. Marshall, Giovanni Perini, Michelle Haber, Murray D. Norris
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2450.
https://doi.org/10.1158/1538-7445.AM2016-2450
Published: 15 July 2016
View articletitled, Abstract 2450: MYCN and TFAP4 promote neuroblastoma malignancy by cooperating in the regulation a subset of target genes involved in cancer cell growth and metastasis
Journal Articles

WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma

Yuting Sun, Jessica L. Bell, Daniel Carter, Samuele Gherardi, Rebecca C. Poulos, Giorgio Milazzo, Jason W.H. Wong, Rima Al-Awar, Andrew E. Tee, Pei Y. Liu, Bing Liu, Bernard Atmadibrata, Matthew Wong, Toby Trahair, Quan Zhao, Jason M. Shohet, Ygal Haupt, Johannes H. Schulte, Peter J. Brown, Cheryl H. Arrowsmith, Masoud Vedadi, Karen L. MacKenzie, Stefan Hüttelmaier, Giovanni Perini, Glenn M. Marshall, Antony Braithwaite, Tao Liu
Journal: Cancer Research
Cancer Res (2015) 75 (23): 5143–5154.
https://doi.org/10.1158/0008-5472.CAN-15-0423
Published: 30 November 2015
View articletitled, WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma
Open the PDF for WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma in another window
Includes: Supplementary data
Journal Articles

Abstract 3808: MYCN coordinately regulates the entire polyamine gene pathway to drive polyamine biosynthesis in neuroblastoma, with expression of every synthetic and catabolic polyamine pathway gene being highly prognostic of clinical outcome.

Murray D. Norris, Laura D. Gamble, Jayne Murray, Stefania Purgato, Giorgio Milazzo, Lesley J. Ashton, Andrei Oberthuer, Wendy B. London, Mike D. Hogarty, Mattias Fischer, David Ziegler, Glenn M. Marshall, Giovanni Perini, Michelle Haber
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3808.
https://doi.org/10.1158/1538-7445.AM2013-3808
Published: 15 April 2013
View articletitled, Abstract 3808: MYCN coordinately regulates the entire polyamine gene pathway to drive polyamine biosynthesis in neuroblastoma, with expression of every synthetic and catabolic polyamine pathway gene being highly prognostic of clinical outcome.