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Giorgio Caravatti
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Journal Articles

Abstract 3743: NVP-BYL719, a selective inhibitor of the class Ia PI3K isoform alpha impairs angiogenesis and microvascular permeability.

Christian R. Schnell, Stephanie Barbe, Giorgio Caravatti, Saskia Brachmann, Daniel Guthy, Sauveur Michel Maira, Robert Cozens, Francesco Hofmann, Christine Fritsch
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3743.
https://doi.org/10.1158/1538-7445.AM2012-3743
Published: 15 April 2012
View article titled, Abstract 3743: NVP-BYL719, a selective inhibitor of the class Ia PI3K isoform alpha impairs angiogenesis and microvascular permeability.
Journal Articles

Abstract 3748: NVP-BYL719, a novel PI3Kalpha selective inhibitor with all the characteristics required for clinical development as an anti-cancer agent

Christine M. Fritsch, Christian Schnell, Christian Chatenay-Rivauday, Daniel A. Guthy, Alain De Pover, Markus Wartmann, Saskia Brachmann, Sauveur-Michel Maira, Alan Huang, Cornelia Quadt, Francesco Hofmann, Giorgio Caravatti
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3748.
https://doi.org/10.1158/1538-7445.AM2012-3748
Published: 15 April 2012
View article titled, Abstract 3748: NVP-BYL719, a novel PI3Kalpha selective inhibitor with all the characteristics required for clinical development as an anti-cancer agent
Journal Articles

Abstract 1922: 2-Aminothiazoles as potent and selective PI3Kalpha inhibitors: Discovery of NVP-BYL719 and structural basis for the isoform selectivity

Giorgio Caravatti, Vito Guagnano, Robin Fairhurst, Patricia Imbach, Ian Bruce, Mark Knapp, Pascal Furet, Christine Fritsch, Alain De Pover, Francesca Blasco, Joachim Blanz, Frank H. Seiler, Doriano Fabbro, Marc Lang
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1922.
https://doi.org/10.1158/1538-7445.AM2012-1922
Published: 15 April 2012
View article titled, Abstract 1922: 2-Aminothiazoles as potent and selective PI3Kalpha inhibitors: Discovery of NVP-BYL719 and structural basis for the isoform selectivity
Journal Articles

The RET Kinase Inhibitor NVP-AST487 Blocks Growth and Calcitonin Gene Expression through Distinct Mechanisms in Medullary Thyroid Cancer Cells

Nagako Akeno-Stuart, Michelle Croyle, Jeffrey A. Knauf, Roberta Malaguarnera, Donata Vitagliano, Massimo Santoro, Christine Stephan, Konstantina Grosios, Markus Wartmann, Robert Cozens, Giorgio Caravatti, Doriano Fabbro, Heidi A. Lane, James A. Fagin
Journal: Cancer Research
Cancer Res (2007) 67 (14): 6956–6964.
https://doi.org/10.1158/0008-5472.CAN-06-4605
Published: 17 July 2007
View article titled, The RET Kinase Inhibitor NVP-AST487 Blocks Growth and Calcitonin Gene Expression through Distinct Mechanisms in Medullary Thyroid Cancer Cells
Open the PDF for The RET Kinase Inhibitor NVP-AST487 Blocks Growth and Calcitonin Gene Expression through Distinct Mechanisms in Medullary Thyroid Cancer Cells in another window
Journal Articles

AEE788: A Dual Family Epidermal Growth Factor Receptor/ErbB2 and Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor with Antitumor and Antiangiogenic Activity

Peter Traxler, Peter R. Allegrini, Ralf Brandt, Josef Brueggen, Robert Cozens, Doriano Fabbro, Konstantina Grosios, Heidi A. Lane, Paul McSheehy, Jürgen Mestan, Thomas Meyer, Careen Tang, Markus Wartmann, Jeanette Wood, Giorgio Caravatti
Journal: Cancer Research
Cancer Res (2004) 64 (14): 4931–4941.
https://doi.org/10.1158/0008-5472.CAN-03-3681
Published: 15 July 2004
View article titled, AEE788: <subtitle>A Dual Family Epidermal Growth Factor Receptor/ErbB2 and Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor with Antitumor and Antiangiogenic Activity</subtitle>
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Journal Articles

New S-Adenosylmethionine Decarboxylase Inhibitors with Potent Antitumor Activity

Urs Regenass, Giorgio Caravatti, Helmut Mett, Jaroslav Stanek, Peter Schneider, Marcel Müller, Alex Matter, Paula Vertino, Carl W. Porter
Journal: Cancer Research
Cancer Res (1992) 52 (17): 4712–4718.
Published: 01 September 1992
View article titled, New <em>S</em>-Adenosylmethionine Decarboxylase Inhibitors with Potent Antitumor Activity
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