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Journal Articles

Abstract PO-125: Targeting histone methylation to overrule transcriptionally driven drug resistance in myeloid leukemia

Noortje van Gils, Han J.M.P. Verhagen, Tània Martiáñez, Fedor Denkers, Eline Vermue, Arjo Rutten, Tamás Csikós, Meyrem Çil, Marjon Al, Frank van Gemert, Jeroen J.W.M. Janssen, Gert J. Ossenkoppele, Renee X. Menezes, Linda Smit

Cancer Res (2020) 80 (21_Supplement): PO-125.

https://doi.org/10.1158/1538-7445.TUMHET2020-PO-125

Published: 03 November 2020

View article titled, Abstract PO-125: Targeting histone methylation to overrule transcriptionally driven drug resistance in myeloid leukemia

Journal Articles

Abstract 1114: IGFBP7 reduces acute myeloid leukemia stem cell survival without affecting normal hematopoiesis

Han J. Verhagen, Noortje van Gils, Anna van Rhenen, Arjo Rutten, Marjon Smit, Mei-Ling Tsui, Louise L. de Vos Klootwijk, Renee X. Menezes, Meyram Cil, Margaretha G. Roemer, Fabio Brocco, Fedor Denkers, Eline Vermue, Stan Heukelom, Sonja Zweegman, Jeroen J. Janssen, Gert J. Ossenkoppele, Gerrit Jan Schuurhuis, Linda Smit

Cancer Res (2018) 78 (13_Supplement): 1114.

https://doi.org/10.1158/1538-7445.AM2018-1114

Published: 01 July 2018

View article titled, Abstract 1114: IGFBP7 reduces acute myeloid leukemia stem cell survival without affecting normal hematopoiesis

Journal Articles

Abstract 1820: Phosphoproteomics of a panel of AML cell lines reveals oncogenic signaling and candidate drivers

Carolien van Alphen, Jacqueline Cloos, Sander R. Piersma, Jaco C. Knol, Thang V. Pham, Gert J. Ossenkoppele, Henk Verheul, Jeroen JWM Janssen, Connie R. Jimenez

Cancer Res (2015) 75 (15_Supplement): 1820.

https://doi.org/10.1158/1538-7445.AM2015-1820

Published: 01 August 2015

View article titled, Abstract 1820: Phosphoproteomics of a panel of AML cell lines reveals oncogenic signaling and candidate drivers

Journal Articles

Abstract 3890: MicroRNA-551b is highly expressed in hematopoietic stem cells and expression in acute myeloid leukemia is associated with relapse and poor survival

David C. de leeuw, Fedor Denkers, Peter Valk, Iris de Rink, Ron Kerkhoven, Gerrit Jan Schuurhuis, Gert J. Ossenkoppele, Linda Smit

Cancer Res (2014) 74 (19_Supplement): 3890.

https://doi.org/10.1158/1538-7445.AM2014-3890

Published: 01 October 2014

View article titled, Abstract 3890: MicroRNA-551b is highly expressed in hematopoietic stem cells and expression in acute myeloid leukemia is associated with relapse and poor survival

Journal Articles

Attenuation of microRNA-126 Expression That Drives CD34⁺38⁻ Stem/Progenitor Cells in Acute Myeloid Leukemia Leads to Tumor Eradication

David C. de Leeuw, Fedor Denkers, Marjolein C. Olthof, Arjo P. Rutten, Walter Pouwels, Gerrit Jan Schuurhuis, Gert J. Ossenkoppele, Linda Smit

Cancer Res (2014) 74 (7): 2094–2105.

https://doi.org/10.1158/0008-5472.CAN-13-1733

Published: 31 March 2014

View article titled, Attenuation of microRNA-126 Expression That Drives CD34+38− Stem/Progenitor Cells in Acute Myeloid Leukemia Leads to Tumor Eradication

Includes: Supplementary data

Journal Articles

Abstract LB-246: MicroRNA profiling can classify acute leukemias of ambiguous lineage as either acute myeloid leukemia or acute lymphoid leukemia.

Dave C. de Leeuw, Willemijn van den Ancker, Fedor Denkers, Rene X. Menezes, Theresia M. Westers, Gert J. Ossenkoppele, Arjan A. van de Loosdrecht, Linda Smit

Cancer Res (2013) 73 (8_Supplement): LB-246.

https://doi.org/10.1158/1538-7445.AM2013-LB-246

Published: 15 April 2013

View article titled, Abstract LB-246: MicroRNA profiling can classify acute leukemias of ambiguous lineage as either acute myeloid leukemia or acute lymphoid leukemia.

Journal Articles

Abstract LB-45: High aldehyde dehydrogenase activity is a marker for normal hematopoietic stem cells but not leukemic stem cells in acute myeloid leukemia: novel therapeutic implications.

Gerrit Jan Schuurhuis, Lisa A. Min, Michael H. Meel, Rolf Wouters, Monique Terwijn, Angele Kelder, Alexander N. Snel, Gert J. Ossenkoppele, Linda Smit

Cancer Res (2011) 71 (8_Supplement): LB-45.

https://doi.org/10.1158/1538-7445.AM2011-LB-45

Published: 15 April 2011

View article titled, Abstract LB-45: High aldehyde dehydrogenase activity is a marker for normal hematopoietic stem cells but not leukemic stem cells in acute myeloid leukemia: novel therapeutic implications.

Journal Articles

Absence of Class II–Associated Invariant Chain Peptide on Leukemic Blasts of Patients Promotes Activation of Autologous Leukemia-Reactive CD4⁺ T Cells

Marvin M. van Luijn, Willemijn van den Ancker, Martine E.D. Chamuleau, Adri Zevenbergen, Theresia M. Westers, Gert J. Ossenkoppele, S. Marieke van Ham, Arjan A. van de Loosdrecht

Cancer Res (2011) 71 (7): 2507–2517.

https://doi.org/10.1158/0008-5472.CAN-10-3689

Published: 31 March 2011

View article titled, Absence of Class II–Associated Invariant Chain Peptide on Leukemic Blasts of Patients Promotes Activation of Autologous Leukemia-Reactive CD4+ T Cells

Includes: Supplementary data

Journal Articles

C-Type Lectin-Like Molecule-1: A Novel Myeloid Cell Surface Marker Associated with Acute Myeloid Leukemia

Alexander B. H. Bakker, Sonja van den Oudenrijn, Arjen Q. Bakker, Nicole Feller, Marja van Meijer, Judith A. Bia, Mandy A. C. Jongeneelen, Therese J. Visser, Nora Bijl, Cecilia A. W. Geuijen, Wilfred E. Marissen, Katarina Radosevic, Mark Throsby, Gerrit Jan Schuurhuis, Gert J. Ossenkoppele, John de Kruif, Jaap Goudsmit, Ada M. Kruisbeek

Cancer Res (2004) 64 (22): 8443–8450.

https://doi.org/10.1158/0008-5472.CAN-04-1659

Published: 17 November 2004

View article titled, C-Type Lectin-Like Molecule-1: <subtitle>A Novel Myeloid Cell Surface Marker Associated with Acute Myeloid Leukemia</subtitle>

Journal Articles

Class II-Associated Invariant Chain Peptide Expression on Myeloid Leukemic Blasts Predicts Poor Clinical Outcome

Martine E. D. Chamuleau, Yuri Souwer, S. Marieke van Ham, Adri Zevenbergen, Theresia M. Westers, Johannes Berkhof, Chris J. L. M. Meijer, Arjan A. van de Loosdrecht, Gert J. Ossenkoppele

Cancer Res (2004) 64 (16): 5546–5550.

https://doi.org/10.1158/0008-5472.CAN-04-1350

Published: 16 August 2004

View article titled, Class II-Associated Invariant Chain Peptide Expression on Myeloid Leukemic Blasts Predicts Poor Clinical Outcome

Journal Articles

Disruption of etoposide induced caspase activation is common in B-cell lymphomas and B-cell lymphoma derived cell lines but may be overcome by TNF-related apoptosis-inducing ligand (TRAIL).

Saskia A. Cillessen, Chris J. Meijer, Petra Niesten, Gert J. Ossenkoppele, Jettie J. Muris, Kitty Castricum, Wim Vos, Marcel Flens, Frans Graadt van Roggen, Joost J. Oudejans

Cancer Res (2004) 64 (7_Supplement): 783–784.

Published: 01 April 2004

View article titled, Disruption of etoposide induced caspase activation is common in B-cell lymphomas and B-cell lymphoma derived cell lines but may be overcome by TNF-related apoptosis-inducing ligand (TRAIL).

Journal Articles

Cell Cycle Specific Effects of Tumor Necrosis Factor α in Monocyte Mediated Leukemic Cell Death and the Role of β₂-Integrins

Arjan A. van de Loosdrecht, Gert J. Ossenkoppele, Robert H. J. Beelen, Marjolein G. Broekhoven, Mart M. A. C. Langenhuijsen

Cancer Res (1993) 53 (18): 4399–4407.

Published: 01 September 1993

View article titled, Cell Cycle Specific Effects of Tumor Necrosis Factor α in Monocyte Mediated Leukemic Cell Death and the Role of β2-Integrins

NARROW

Abstract PO-125: Targeting histone methylation to overrule transcriptionally driven drug resistance in myeloid leukemia

Abstract 1114: IGFBP7 reduces acute myeloid leukemia stem cell survival without affecting normal hematopoiesis

Abstract 1820: Phosphoproteomics of a panel of AML cell lines reveals oncogenic signaling and candidate drivers

Abstract 3890: MicroRNA-551b is highly expressed in hematopoietic stem cells and expression in acute myeloid leukemia is associated with relapse and poor survival

Attenuation of microRNA-126 Expression That Drives CD34⁺38⁻ Stem/Progenitor Cells in Acute Myeloid Leukemia Leads to Tumor Eradication

Abstract LB-246: MicroRNA profiling can classify acute leukemias of ambiguous lineage as either acute myeloid leukemia or acute lymphoid leukemia.

Abstract LB-45: High aldehyde dehydrogenase activity is a marker for normal hematopoietic stem cells but not leukemic stem cells in acute myeloid leukemia: novel therapeutic implications.

Absence of Class II–Associated Invariant Chain Peptide on Leukemic Blasts of Patients Promotes Activation of Autologous Leukemia-Reactive CD4⁺ T Cells

C-Type Lectin-Like Molecule-1: A Novel Myeloid Cell Surface Marker Associated with Acute Myeloid Leukemia

Class II-Associated Invariant Chain Peptide Expression on Myeloid Leukemic Blasts Predicts Poor Clinical Outcome

Disruption of etoposide induced caspase activation is common in B-cell lymphomas and B-cell lymphoma derived cell lines but may be overcome by TNF-related apoptosis-inducing ligand (TRAIL).

Cell Cycle Specific Effects of Tumor Necrosis Factor α in Monocyte Mediated Leukemic Cell Death and the Role of β₂-Integrins

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