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Journal Articles

Abstract 332: Spliceosome inhibition as novel strategy against diffuse malignant peritoneal mesothelioma

Rocco Sciarrillo, Valentina E. Gomez, Marzia Pennati, Anna Wojtuszkiewicz, Gert-Jan L. Kaspers, Carla Molthoff, Nadia Zaffaroni, Godefridus J. Peters, Gerrit Jansen, Elisa Giovannetti

Cancer Res (2016) 76 (14_Supplement): 332.

https://doi.org/10.1158/1538-7445.AM2016-332

Published: 15 July 2016

View article titled, Abstract 332: Spliceosome inhibition as novel strategy against diffuse malignant peritoneal mesothelioma

Journal Articles

Abstract 4336: Spliceosome inhibition as a novel therapeutic option in acute leukemia

Anna Wojtuszkiewicz, Rocco Sciarrillo, Gerrit Jansen, Yehuda G. Assaraf, Kazunori Koide, Robert K. Bressin, Upamanyu Basu, Edwin Sonneveld, Godefridus J. Peters, Gertjan J L Kaspers, Jacqueline Cloos

Cancer Res (2016) 76 (14_Supplement): 4336.

https://doi.org/10.1158/1538-7445.AM2016-4336

Published: 15 July 2016

View article titled, Abstract 4336: Spliceosome inhibition as a novel therapeutic option in acute leukemia

Journal Articles

Abstract 4437: The relevance of aberrant FPGS splicing for ex vivo MTX resistance and clinical outcome in childhood acute lymphoblastic leukemia

Anna Wojtuszkiewicz, Yehuda G. Assaraf, Mirthe Hoekstra, Gerrit Jansen, Godefridus J. Peters, Edwin Sonneveld, Gertjan L. Kaspers, Jacqueline Cloos

Cancer Res (2015) 75 (15_Supplement): 4437.

https://doi.org/10.1158/1538-7445.AM2015-4437

Published: 01 August 2015

View article titled, Abstract 4437: The relevance of aberrant FPGS splicing for ex vivo MTX resistance and clinical outcome in childhood acute lymphoblastic leukemia

Journal Articles

Abstract 1624: Methotrexate resistance in relation to treatment outcome in childhood acute lymphoblastic leukemia

Anna Wojtuszkiewicz, Godefridus J. Peters, Nicole L. van Woerden, Boas Dubbelman, Gabrielle Escherich, Kjeld Schmiegelow, Edwin Sonneveld, Rob Pieters, Peter M. van de Ven, Gerrit Jansen, Yehuda G. Assaraf, Gertjan J L Kaspers, Jacqueline Cloos

Cancer Res (2015) 75 (15_Supplement): 1624.

https://doi.org/10.1158/1538-7445.AM2015-1624

Published: 01 August 2015

View article titled, Abstract 1624: Methotrexate resistance in relation to treatment outcome in childhood acute lymphoblastic leukemia

Journal Articles

Abstract 4764: Transfer of regulatory protein networks via extracellular vesicles as a candidate mechanism of apoptosis-resistance in acute myeloid leukemia

Anna Wojtuszkiewicz, Jacqueline Cloos, Floortje L. Kessler, Sander Piersma, Jako Knol, Gerrit Jansen, Yehuda G. Assaraf, Gertjan L. Kaspers, Sonja Zweegman, Gerrit J. Schuurhuis, Connie R. Jimenez

Cancer Res (2014) 74 (19_Supplement): 4764.

https://doi.org/10.1158/1538-7445.AM2014-4764

Published: 01 October 2014

View article titled, Abstract 4764: Transfer of regulatory protein networks via extracellular vesicles as a candidate mechanism of apoptosis-resistance in acute myeloid leukemia

Journal Articles

Abstract LB-169: Ratios of immunoproteasome over constitutive proteasome expression are an indicator for sensitivity to bortezomib-containing reinduction chemotherapy in pediatric relapsed ALL and AML

Denise Niewerth, Gertjan J.L. Kaspers, Gerrit Jansen, Johan van Meerloo, Sonja Zweegman, Gaye Jenkins, James A. Whitlock, Stephen P. Hunger, Xiaomin Lu, Jacqueline Cloos, Terzah M. Horton

Cancer Res (2014) 74 (19_Supplement): LB-169.

https://doi.org/10.1158/1538-7445.AM2014-LB-169

Published: 01 October 2014

View article titled, Abstract LB-169: Ratios of immunoproteasome over constitutive proteasome expression are an indicator for sensitivity to bortezomib-containing reinduction chemotherapy in pediatric relapsed ALL and AML

Journal Articles

Abstract 4628: Alterations in FPGS splicing as a plausible underlying mechanism of MTX resistance in ALL.

Anna Wojtuszkiewicz, Yehuda Assaraf, Shachar Raz, Michal Stark, Edwin Sonneveld, Godefridus Peters, Gerrit Jansen, Gertjan Kaspers, Jacqueline Cloos

Cancer Res (2013) 73 (8_Supplement): 4628.

https://doi.org/10.1158/1538-7445.AM2013-4628

Published: 15 April 2013

View article titled, Abstract 4628: Alterations in FPGS splicing as a plausible underlying mechanism of MTX resistance in ALL.

Journal Articles

Abstract 746: Acquired bortezomib resistance in non-small cell lung cancer is associated with overexpression of the mutated β5 proteasome subunit

Leonie H.A.M. de Wilt, Gerrit Jansen, Yehuda G. Assaraf, Johan van Meerloo, Jacqueline Cloos, Aaron D. Schimmer, Godefridus J. Peters, Frank A.E. Kruyt

Cancer Res (2011) 71 (8_Supplement): 746.

https://doi.org/10.1158/1538-7445.AM2011-746

Published: 15 April 2011

View article titled, Abstract 746: Acquired bortezomib resistance in non-small cell lung cancer is associated with overexpression of the mutated β5 proteasome subunit

Journal Articles

Abstract 2627: Mechanisms of bortezomib resistance in human NSCLC cell lines; potential role of proteasome beta5-subunits and autophagy

Leonie H.A.M. de Wilt, Gerrit Jansen, Aaron D. Schimmer, Godefridus J. Peters, Frank A.E. Kruyt

Cancer Res (2010) 70 (8_Supplement): 2627.

https://doi.org/10.1158/1538-7445.AM10-2627

Published: 15 April 2010

View article titled, Abstract 2627: Mechanisms of bortezomib resistance in human NSCLC cell lines; potential role of proteasome beta5-subunits and autophagy

Journal Articles

BCRP-mediated resistance to the EGFR tyrosine kinase inhibitors (TKIs) gefitinib and erlotinib

Clara Lemos, Ietje Kathmann, Elisa Giovannetti, Gerrit Jansen, Godefridus Peters

Cancer Res (2008) 68 (9_Supplement): 3246.

Published: 01 May 2008

View article titled, BCRP-mediated resistance to the EGFR tyrosine kinase inhibitors (TKIs) gefitinib and erlotinib

Journal Articles

Impact of cellular folate status on multidrug resistance transporters BCRP and MRP expression in a panel of high (HF) and low folate (LF) cells

Clara Lemos, Ietje Kathmann, Gerrit Jansen, Godefridus Peters

Cancer Res (2007) 67 (9_Supplement): 2297.

Published: 01 May 2007

View article titled, Impact of cellular folate status on multidrug resistance transporters BCRP and MRP expression in a panel of high (HF) and low folate (LF) cells

Journal Articles

Folate deprivation/supplementation modulates BCRP and MRP1 expression in cancer cells from a different origin

Clara Lemos, Ietje Kathmann, Jan H. Hooijberg, Gerrit Jansen, Godefridus J. Peters

Cancer Res (2006) 66 (8_Supplement): 146.

Published: 15 April 2006

View article titled, Folate deprivation/supplementation modulates BCRP and MRP1 expression in cancer cells from a different origin

Journal Articles

Multidrug resistance-related ATP-binding cassette (ABC) transporters in dendritic cell functions

Rieneke Van de Ven, Mariska C. De Jong, Anneke W. Reurs, Antoinet J. Schoonderwoerd, Gerrit Jansen, Jan H. Hooijberg, George L. Scheffer, Tanja D. De Gruijl, Rik J. Scheper

Cancer Res (2006) 66 (8_Supplement): 1145.

Published: 15 April 2006

View article titled, Multidrug resistance-related ATP-binding cassette (ABC) transporters in dendritic cell functions

Journal Articles

ABCG2 Harboring the Gly482 Mutation Confers High-Level Resistance to Various Hydrophilic Antifolates

Assaf Shafran, Ilan Ifergan, Eran Bram, Gerrit Jansen, Ietje Kathmann, Godefridus J. Peters, Robert W. Robey, Susan E. Bates, Yehuda G. Assaraf

Cancer Res (2005) 65 (18): 8414–8422.

https://doi.org/10.1158/0008-5472.CAN-04-4547

Published: 15 September 2005

View article titled, ABCG2 Harboring the Gly482 Mutation Confers High-Level Resistance to Various Hydrophilic Antifolates

Journal Articles

The Human Multidrug Resistance Protein MRP5 Transports Folates and Can Mediate Cellular Resistance against Antifolates

Peter Wielinga, Jan Hendrik Hooijberg, Sjofn Gunnarsdottir, Ietje Kathmann, Glen Reid, Noam Zelcer, Kasper van der Born, Marcel de Haas, Ingrid van der Heijden, Gertjan Kaspers, Jan Wijnholds, Gerrit Jansen, Godefridus Peters, Piet Borst

Cancer Res (2005) 65 (10): 4425–4430.

https://doi.org/10.1158/0008-5472.CAN-04-2810

Published: 16 May 2005

View article titled, The Human Multidrug Resistance Protein MRP5 Transports Folates and Can Mediate Cellular Resistance against Antifolates

Journal Articles

Kinetics of antifolate transport via the reduced folate carrier and the membrane folate receptor in murine cells in vitro and in vivo

Robert Mauritz, Gerrit Jansen, Godefridus J. Peters

Cancer Res (2005) 65 (9_Supplement): 776–777.

Published: 01 May 2005

View article titled, Kinetics of antifolate transport via the reduced folate carrier and the membrane folate receptor in murine cells in vitro and in vivo

Journal Articles

Increased glucocorticoid sensitivity of leukemic cells by inhibiting NFκB activation

Josefien Vink, Ruud Oerlemans, Jacqueline Cloos, Joost Van der Heijden, Ben Dijkmans, Gerrit Jansen, Gertjan Kaspers

Cancer Res (2005) 65 (9_Supplement): 1399.

Published: 01 May 2005

View article titled, Increased glucocorticoid sensitivity of leukemic cells by inhibiting NFκB activation

Journal Articles

Sulphasalazine down-regulates the expression of angiogenic factors, platelet derived endothelial cell growth factor / Thymidine phosphorylase (PD-ECGF /TP) and Interleukin 8 (IL-8) in human monocytic THP-1 and U937 cells

Michiel De Bruin, Ruud Oerlemans, Allan J. Masterson, Yehuda G. Assaraf, Ben A. C. Dijkmans, Auke D. Adema, Klaas Hoekman, Herbert M. Pinedo, Gerrit Jansen, Godefridus J. Peters

Cancer Res (2004) 64 (7_Supplement): 945–946.

Published: 01 April 2004

View article titled, Sulphasalazine down-regulates the expression of angiogenic factors, platelet derived endothelial cell growth factor / Thymidine phosphorylase (PD-ECGF /TP) and Interleukin 8 (IL-8) in human monocytic THP-1 and U937 cells

Journal Articles

Selective Delivery of CB300638, a Cyclopenta[ g ]quinazoline-based Thymidylate Synthase Inhibitor into Human Tumor Cell Lines Overexpressing the α-Isoform of the Folate Receptor

Davinder S. Theti, Vassilios Bavetsias, Lorraine A. Skelton, Jenny Titley, David Gibbs, Gerrit Jansen, Ann L. Jackman

Cancer Res (2003) 63 (13): 3612–3618.

Published: 01 July 2003

View article titled, Selective Delivery of CB300638, a Cyclopenta[ <em>g</em> ]quinazoline-based Thymidylate Synthase Inhibitor into Human Tumor Cell Lines Overexpressing the α-Isoform of the Folate Receptor

Journal Articles

Modulation of Both Endogenous Folates and Thymidine Enhance the Therapeutic Efficacy of Thymidylate Synthase Inhibitors

Clasina L. van der Wilt, Harold H. J. Backus, Kees Smid, Lizzy Comijn, Gijsbert Veerman, Dorine Wouters, Daphne A. Voorn, David G. Priest, Marlene A. Bunni, Fraser Mitchell, Ann L. Jackman, Gerrit Jansen, Godefridus J. Peters

Cancer Res (2001) 61 (9): 3675–3681.

Published: 01 May 2001

View article titled, Modulation of Both Endogenous Folates and Thymidine Enhance the Therapeutic Efficacy of Thymidylate Synthase Inhibitors

NARROW

Abstract 332: Spliceosome inhibition as novel strategy against diffuse malignant peritoneal mesothelioma

Abstract 4336: Spliceosome inhibition as a novel therapeutic option in acute leukemia

Abstract 4437: The relevance of aberrant FPGS splicing for ex vivo MTX resistance and clinical outcome in childhood acute lymphoblastic leukemia

Abstract 1624: Methotrexate resistance in relation to treatment outcome in childhood acute lymphoblastic leukemia

Abstract 4764: Transfer of regulatory protein networks via extracellular vesicles as a candidate mechanism of apoptosis-resistance in acute myeloid leukemia

Abstract LB-169: Ratios of immunoproteasome over constitutive proteasome expression are an indicator for sensitivity to bortezomib-containing reinduction chemotherapy in pediatric relapsed ALL and AML

Abstract 4628: Alterations in FPGS splicing as a plausible underlying mechanism of MTX resistance in ALL.

Abstract 746: Acquired bortezomib resistance in non-small cell lung cancer is associated with overexpression of the mutated β5 proteasome subunit

Abstract 2627: Mechanisms of bortezomib resistance in human NSCLC cell lines; potential role of proteasome beta5-subunits and autophagy

BCRP-mediated resistance to the EGFR tyrosine kinase inhibitors (TKIs) gefitinib and erlotinib

Impact of cellular folate status on multidrug resistance transporters BCRP and MRP expression in a panel of high (HF) and low folate (LF) cells

Folate deprivation/supplementation modulates BCRP and MRP1 expression in cancer cells from a different origin

Multidrug resistance-related ATP-binding cassette (ABC) transporters in dendritic cell functions

ABCG2 Harboring the Gly482 Mutation Confers High-Level Resistance to Various Hydrophilic Antifolates

The Human Multidrug Resistance Protein MRP5 Transports Folates and Can Mediate Cellular Resistance against Antifolates

Kinetics of antifolate transport via the reduced folate carrier and the membrane folate receptor in murine cells in vitro and in vivo

Increased glucocorticoid sensitivity of leukemic cells by inhibiting NFκB activation

Sulphasalazine down-regulates the expression of angiogenic factors, platelet derived endothelial cell growth factor / Thymidine phosphorylase (PD-ECGF /TP) and Interleukin 8 (IL-8) in human monocytic THP-1 and U937 cells

Selective Delivery of CB300638, a Cyclopenta[ g ]quinazoline-based Thymidylate Synthase Inhibitor into Human Tumor Cell Lines Overexpressing the α-Isoform of the Folate Receptor

Modulation of Both Endogenous Folates and Thymidine Enhance the Therapeutic Efficacy of Thymidylate Synthase Inhibitors

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