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Gerhard Christofori
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Journal Articles

A Pygopus 2-Histone Interaction Is Critical for Cancer Cell Dedifferentiation and Progression in Malignant Breast Cancer

Meera Saxena, Ravi K.R. Kalathur, Natalia Rubinstein, Andrea Vettiger, Nami Sugiyama, Melanie Neutzner, Mairene Coto-Llerena, Venkatesh Kancherla, Caner Ercan, Salvatore Piscuoglio, Jonas Fischer, Ernesta Fagiani, Claudio Cantù, Konrad Basler, Gerhard Christofori
Journal: Cancer Research
Cancer Res (2020) 80 (17): 3631–3648.
https://doi.org/10.1158/0008-5472.CAN-19-2910
Published: 02 September 2020
View articletitled, A Pygopus 2-Histone Interaction Is Critical for Cancer Cell Dedifferentiation and Progression in Malignant Breast Cancer
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Includes: Multimedia, Supplementary data
Journal Articles

Targeting Cancer Cell Metastasis by Converting Cancer Cells into Fat

Dana Ishay-Ronen, Gerhard Christofori
Journal: Cancer Research
Cancer Res (2019) 79 (21): 5471–5475.
https://doi.org/10.1158/0008-5472.CAN-19-1242
Published: 01 November 2019
View articletitled, Targeting Cancer Cell Metastasis by Converting Cancer Cells into Fat
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Journal Articles

VEGF-Mediated Angiogenesis Links EMT-Induced Cancer Stemness to Tumor Initiation

Anna Fantozzi, Dorothea C. Gruber, Laura Pisarsky, Chantal Heck, Akiko Kunita, Mahmut Yilmaz, Nathalie Meyer-Schaller, Karen Cornille, Ulrike Hopfer, Mohamed Bentires-Alj, Gerhard Christofori
Journal: Cancer Research
Cancer Res (2014) 74 (5): 1566–1575.
https://doi.org/10.1158/0008-5472.CAN-13-1641
Published: 02 March 2014
View articletitled, VEGF-Mediated Angiogenesis Links EMT-Induced Cancer Stemness to Tumor Initiation
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Includes: Multimedia, Supplementary data
Journal Articles

Abstract 5714: Combination of glucagon-like-peptide-1 (GLP-1) receptor targeted therapy with anti-angiogenic compounds in a mouse model of neuroendocrine tumors

Andreas Wicki, Damian Wild, Annette Orleth, Christoph Rochlitz, Christoph Mamot, Gerhard Christofori
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5714.
https://doi.org/10.1158/1538-7445.AM2012-5714
Published: 15 April 2012
View articletitled, Abstract 5714: Combination of glucagon-like-peptide-1 (GLP-1) receptor targeted therapy with anti-angiogenic compounds in a mouse model of neuroendocrine tumors
Journal Articles

Angiopoietin-1 and -2 Exert Antagonistic Functions in Tumor Angiogenesis, yet Both Induce Lymphangiogenesis

Ernesta Fagiani, Pascal Lorentz, Lucie Kopfstein, Gerhard Christofori
Journal: Cancer Research
Cancer Res (2011) 71 (17): 5717–5727.
https://doi.org/10.1158/0008-5472.CAN-10-4635
Published: 30 August 2011
View articletitled, Angiopoietin-1 and -2 Exert Antagonistic Functions in Tumor Angiogenesis, yet Both Induce Lymphangiogenesis
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Includes: Supplementary data
Journal Articles

Proangiogenic Factor PlGF Programs CD11b+ Myelomonocytes in Breast Cancer during Differentiation of Their Hematopoietic Progenitors

Julien Laurent, Eveline Faes-van't Hull, Cedric Touvrey, François Kuonen, Qiang Lan, Girieca Lorusso, Marie-Agnès Doucey, Laura Ciarloni, Natsuko Imaizumi, Gian Carlo Alghisi, Ernesta Fagiani, Khalil Zaman, Roger Stupp, Masabumi Shibuya, Jean-François Delaloye, Gerhard Christofori, Curzio Ruegg
Journal: Cancer Research
Cancer Res (2011) 71 (11): 3781–3791.
https://doi.org/10.1158/0008-5472.CAN-10-3684
Published: 31 May 2011
View articletitled, Proangiogenic Factor PlGF Programs CD11b+ Myelomonocytes in Breast Cancer during Differentiation of Their Hematopoietic Progenitors
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Includes: Supplementary data
Journal Articles

Abstract 3634: Selective targeting of tumor-associated angiogenic tip and stalk cells with immunoliposomes (ILs) directed against VEGFR-2 and VEGFR-3 expressing cells

Andreas Wicki, Christoph Rochlitz, Annette Orleth, Reto Ritschard, Kari Alitalo, Richard Herrmann, Gerhard Christofori, Christoph Mamot
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3634.
https://doi.org/10.1158/1538-7445.AM2011-3634
Published: 15 April 2011
View articletitled, Abstract 3634: Selective targeting of tumor-associated angiogenic tip and stalk cells with immunoliposomes (ILs) directed against VEGFR-2 and VEGFR-3 expressing cells
Journal Articles

Abstract LB-362: PlGF inhibition phenocopies PlGF deficiency in cancer

Thomas Schmidt, Sara Van de Veire, Femke Heindryckx, Hajimu Oura, Annemilaï Tijeras-Raballand, Sonja Loges, Imke Albrecht, Bart Jonckx, Stefan Vinckier, Christophe Van Steenkiste, Sònia Tugues, Charlotte Rolny, Maria De Mol, Daniela Dettori, Patricia Hainaud, Lieve Coenegrachts, Jean-Olivier Contreres, Henar Cuervo, Carole Le Henaff, Ian Buysschaert, Behzad Kharabi Masouleh, Anja Geerts, Tibor Schomber, Philippe Bonnin, Juergen Haustraete, Serena Zacchigna, Wladimiro Jiménez, Mauro Giacca, Isabelle Colle, Gerard Tobelem, Manuel Morales-Ruiz, José Vilar, Geert Carmeliet, Mieke Dewerchin, Lena Claesson-Welsh, Evelyne Dupuy, Hans Van Vlierberghe, Gerhard Christofori, Massimiliano Mazzone, Michael Detmar, Désiré Collen, Peter Carmeliet
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): LB-362.
https://doi.org/10.1158/1538-7445.AM10-LB-362
Published: 15 April 2010
View articletitled, Abstract LB-362: PlGF inhibition phenocopies PlGF deficiency in cancer
Journal Articles

Abstract #3657: Targeting of VEGFR-2 expressing endothelial cells with cytotoxic compounds as a novel anti-angiogenic approach

Andreas Wicki, Christoph Rochlitz, Reto Ritschard, Gerhard Christofori, Christoph Mamot
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3657.
Published: 01 May 2009
View articletitled, Abstract #3657: Targeting of VEGFR-2 expressing endothelial cells with cytotoxic compounds as a novel anti-angiogenic approach
Journal Articles

Placental Growth Factor-1 Attenuates Vascular Endothelial Growth Factor-A–Dependent Tumor Angiogenesis during β Cell Carcinogenesis

Tibor Schomber, Lucie Kopfstein, Valentin Djonov, Imke Albrecht, Vanessa Baeriswyl, Karin Strittmatter, Gerhard Christofori
Journal: Cancer Research
Cancer Res (2007) 67 (22): 10840–10848.
https://doi.org/10.1158/0008-5472.CAN-07-1034
Published: 15 November 2007
View articletitled, Placental Growth Factor-1 Attenuates Vascular Endothelial Growth Factor-A–Dependent Tumor Angiogenesis during β Cell Carcinogenesis
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Includes: Supplementary data
Journal Articles

Loss of Neural Cell Adhesion Molecule Induces Tumor Metastasis by Up-regulating Lymphangiogenesis

Ivana Crnic, Karin Strittmatter, Ugo Cavallaro, Lucie Kopfstein, Lotta Jussila, Kari Alitalo, Gerhard Christofori
Journal: Cancer Research
Cancer Res (2004) 64 (23): 8630–8638.
https://doi.org/10.1158/0008-5472.CAN-04-2523
Published: 01 December 2004
View articletitled, Loss of Neural Cell Adhesion Molecule Induces Tumor Metastasis by Up-regulating Lymphangiogenesis
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Includes: Supplementary data
Journal Articles

Overexpression of Vascular Endothelial Growth Factor-A165 Enhances Tumor Angiogenesis but not Metastasis during β-Cell Carcinogenesis

Grainne Gannon, Stefano J. Mandriota, Lin Cui, Danielle Baetens, Michael S. Pepper, Gerhard Christofori
Journal: Cancer Research
Cancer Res (2002) 62 (2): 603–608.
Published: 01 January 2002
View articletitled, Overexpression of Vascular Endothelial Growth Factor-A165 Enhances Tumor Angiogenesis but not Metastasis during β-Cell Carcinogenesis
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Journal Articles

Fibroblast Growth Factors Are Required for Efficient Tumor Angiogenesis

Amelia Compagni, Petra Wilgenbus, Maria-Antonietta Impagnatiello, Matt Cotten, Gerhard Christofori
Journal: Cancer Research
Cancer Res (2000) 60 (24): 7163–7169.
Published: 01 December 2000
View articletitled, Fibroblast Growth Factors Are Required for Efficient Tumor Angiogenesis
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Journal Articles

An Insulin-like Growth Factor-mediated, Phosphatidylinositol 3′ Kinase-independent Survival Signaling Pathway in β Tumor Cells

Ingo Burtscher, Amelia Compagni, Gábor M. Lamm, Gerhard Christofori
Journal: Cancer Research
Cancer Res (1999) 59 (16): 3923–3926.
Published: 15 August 1999
View articletitled, An Insulin-like Growth Factor-mediated, Phosphatidylinositol 3′ Kinase-independent Survival Signaling Pathway in β Tumor Cells
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Journal Articles

Impairment of Survival Factor Function Potentiates Chemotherapy-induced Apoptosis in Tumor Cells

Gábor M. Lamm, Gerhard Christofori
Journal: Cancer Research
Cancer Res (1998) 58 (4): 801–807.
Published: 01 February 1998
View articletitled, Impairment of Survival Factor Function Potentiates Chemotherapy-induced Apoptosis in Tumor Cells
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Journal Articles

Tumor Suppressor Loci on Mouse Chromosomes 9 and 16 Are Lost at Distinct Stages of Tumorigenesis in a Transgenic Model of Islet Cell Carcinoma

Sareh Parangi, William Dietrich, Gerhard Christofori, Eric S. Lander, Douglas Hanahan
Journal: Cancer Research
Cancer Res (1995) 55 (24): 6071–6076.
Published: 01 December 1995
View articletitled, Tumor Suppressor Loci on Mouse Chromosomes 9 and 16 Are Lost at Distinct Stages of Tumorigenesis in a Transgenic Model of Islet Cell Carcinoma
Open the PDF for Tumor Suppressor Loci on Mouse Chromosomes 9 and 16 Are Lost at Distinct Stages of Tumorigenesis in a Transgenic Model of Islet Cell Carcinoma in another window