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Georgina V. Long
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Journal Articles

Abstract 6552: Intratumoral (ITu) delivery of mRNA-2752 encoding human OX40L/IL-23/IL-36γ in combination with durvalumab induces an immunostimulatory effect within the tumor microenvironment (TME) of patients with advanced solid tumors

Michael Abadier, Ryan J. Sullivan, Jacky Chow, Vasudha Sehgal, Randy F. Sweis, Adil Daud, Ronnie Shapira-Frommer, Ruth Perets, Shivaani Kummar, Meredith McKean, Ravit Geva, Manish R. Patel, Adnan Khattak, Pablo Fernandez-Peñas, Sima Zacharek, Natalia Wahl, Russell M. Walker, Linh Van, Praveen Aanur, Jim Ward, Khanh T. Do, Georgina V. Long
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6552.
https://doi.org/10.1158/1538-7445.AM2024-6552
Published: 22 March 2024
View article titled, Abstract 6552: Intratumoral (ITu) delivery of mRNA-2752 encoding human OX40L/IL-23/IL-36γ in combination with durvalumab induces an immunostimulatory effect within the tumor microenvironment (TME) of patients with advanced solid tumors
Journal Articles

Abstract 5563: Novel approaches to measuring tumor-mutational burden provide insights into tumor-immune interaction in primary melanoma

Eva R. Shteinman, Nigel Maher, Jordan W. Conway, Grace H. Attrill, Felicity Newell, Nic Waddell, Nicholas Hayward, John V. Pearson, Georgina V. Long, Richard A. Scolyer, James S. Wilmott, Ismael A. Vergara
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5563.
https://doi.org/10.1158/1538-7445.AM2024-5563
Published: 22 March 2024
View article titled, Abstract 5563: Novel approaches to measuring tumor-mutational burden provide insights into tumor-immune interaction in primary melanoma
Journal Articles

Abstract 6681: Altered microbial community stability and increases in circulating B cells are associated with the development of severe immune related adverse events during ICI-immunotherapy

Rebecca C. Simpson, Erin R. Shanahan, Ines P. Silva, Irene L. Reijers, Judith M. Versluis, Alexander M. Menzies, Gonzalez Maria, Umaimainthan Palendira, James S. Wilmott, Christian Blank, Richard A. Scolyer, Georgina V. Long
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6681.
https://doi.org/10.1158/1538-7445.AM2024-6681
Published: 22 March 2024
View article titled, Abstract 6681: Altered microbial community stability and increases in circulating B cells are associated with the development of severe immune related adverse events during ICI-immunotherapy
Journal Articles

Abstract CT001: A personalized cancer vaccine, mRNA-4157, combined with pembrolizumab versus pembrolizumab in patients with resected high-risk melanoma: Efficacy and safety results from the randomized, open-label Phase 2 mRNA-4157-P201/Keynote-942 trial

Adnan Khattak, Matteo Carlino, Tarek Meniawy, George Ansstas, Theresa Medina, Matthew H. Taylor, Kevin B. Kim, Meredith McKean, Georgina V. Long, Ryan J. Sullivan, Mark Faries, Thuy Tran, Charles Cowey, Andrew Pecora, Jennifer Segar, Victoria Atkinson, Geoffrey T. Gibney, Jason Luke, Sajeve Thomas, Elizabeth Buchbinder, Peijie Hou, Lili Zhu, Tal Zaks, Michelle Brown, Praveen Aanur, Robert S. Meehan, Jeffrey S. Weber
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): CT001.
https://doi.org/10.1158/1538-7445.AM2023-CT001
Published: 29 May 2023
View article titled, Abstract CT001: A personalized cancer vaccine, mRNA-4157, combined with pembrolizumab versus pembrolizumab in patients with resected high-risk melanoma: Efficacy and safety results from the randomized, open-label Phase 2 mRNA-4157-P201/Keynote-942 trial
Journal Articles

Abstract CT002: KEYMAKER-U02 substudy 02C: neoadjuvant pembrolizumab (pembro) + vibostolimab (vibo) or gebasaxturev (geba) or pembro alone followed by adjuvant pembro for stage IIIB-D melanoma

Reinhard Dummer, Caroline Robert, Richard A. Scolyer, Janis M. Taube, Michael T. Tetzlaff, Andrew Hill, Jean-Jacques Grob, David C. Portnoy, Celeste Lebbe, Muhammad A. Khattak, Jonathan Cohen, Gil Bar-Sela, Inderjit Mehmi, Ronnie Shapira Frommer, Nicolas Meyer, Yixin Ren, Mizuho Fukunaga-Kalabis, Clemens Krepler, Georgina V. Long
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): CT002.
https://doi.org/10.1158/1538-7445.AM2023-CT002
Published: 14 April 2023
View article titled, Abstract CT002: KEYMAKER-U02 substudy 02C: neoadjuvant pembrolizumab (pembro) + vibostolimab (vibo) or gebasaxturev (geba) or pembro alone followed by adjuvant pembro for stage IIIB-D melanoma
Journal Articles

Abstract 5701: Predictive biomarker models of immunotherapy response in patients with metastatic melanoma: genomic, transcriptomic, and immune profiles from the Personalised Immunotherapy Program (PIP)

Tuba N. Gide, Nurudeen A. Adegoke, Yizhe Mao, Monica Lennox, Saurab Raj, Camelia Quek, Ismael A. Vergara, Nigel Maher, Alison Potter, Robyn P. Saw, John F. Thompson, Andrew J. Spillane, Kerwin F. Shannon, Matteo S. Carlino, Maria Gonzalez, Serigne N. Lo, Alexander M. Menzies, Inês Pires da Silva, Richard A. Scolyer, Georgina V. Long, James S. Wilmott
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5701.
https://doi.org/10.1158/1538-7445.AM2023-5701
Published: 04 April 2023
View article titled, Abstract 5701: Predictive biomarker models of immunotherapy response in patients with metastatic melanoma: genomic, transcriptomic, and immune profiles from the Personalised Immunotherapy Program (PIP)
Journal Articles

Abstract 2369: Spatial organization of the tumour immune microenvironment (TIME) in primary and metastatic melanoma is associated with patient outcome

Grace Heloise Attrill, Eva R. Shteinman, Xinyu Bai, Felix Marsh-Wakefield, Camelia Quek, Umaimainthan Palendira, Ismael A. Vergara, Georgina V. Long, Richard A. Scolyer, James S. Wilmott
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2369.
https://doi.org/10.1158/1538-7445.AM2023-2369
Published: 04 April 2023
View article titled, Abstract 2369: Spatial organization of the tumour immune microenvironment (TIME) in primary and metastatic melanoma is associated with patient outcome
Journal Articles

Abstract 3463: Longitudinal microbiome-immune dynamics in melanoma patients treated with immune checkpoint inhibitor immunotherapy

Rebecca C. Simpson, Erin R. Shanahan, Marcel Batten, Ines P. Silva, Irene L. Reijers, Judith M. Versluis, Alexander M. Menzies, Maria Gonzalez, Umaimainthan Palendira, Andrew Holmes, James S. Wilmott, Christian U. Blank, Richard A. Scolyer, Georgina V. Long
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3463.
https://doi.org/10.1158/1538-7445.AM2023-3463
Published: 04 April 2023
View article titled, Abstract 3463: Longitudinal microbiome-immune dynamics in melanoma patients treated with immune checkpoint inhibitor immunotherapy
Journal Articles

Abstract 4621: Distinct spatial and molecular maps in the tumour microenvironment of resistant melanoma patients treated with checkpoint inhibitor immunotherapy

Camelia Quek, Aditya Pratapa, Ines Pires da Silva, Ghamdan Al-Eryani, Aaron Mayer, Nenad Bartonicek, Kate Harvey, Oliver Braubach, Robyn P.M. Saw, Jonathan Stretch, Kerwin F. Shannon, Alexander M. Menzies, Richard A. Scolyer, Georgina V. Long, Alexander Swarbrick, James S. Wilmott
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4621.
https://doi.org/10.1158/1538-7445.AM2023-4621
Published: 04 April 2023
View article titled, Abstract 4621: Distinct spatial and molecular maps in the tumour microenvironment of resistant melanoma patients treated with checkpoint inhibitor immunotherapy
Journal Articles

Abstract 81: The association between melanoma liver metastases (mets) and the systemic anti-tumor immune profile

Jordan W. Conway, Felix Marsh-Wakefield, Kazi J. Nahar, Serigne N. Lo, Ismael A. Vergara, Tuba N. Gide, Grace H. Attrill, Jorja Braden, Matteo S. Carlino, Robyn P. Saw, John F. Thompson, Andrew J. Spillane, Kerwin F. Shannon, Brindha Shivalingam, Alexander M. Menzies, Umaimainthan Palendira, James S. Wilmott, Georgina V. Long, Richard A. Scolyer, Ines Pires Da Silva
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 81.
https://doi.org/10.1158/1538-7445.AM2023-81
Published: 04 April 2023
View article titled, Abstract 81: The association between melanoma liver metastases (mets) and the systemic anti-tumor immune profile
Journal Articles

Abstract 5479: A six-protein signature predicts response and survival in patients with advanced cutaneous melanoma treated with immunotherapy

Srikanth Manda, Adel T. Aref, Erin K. Sykes, Steven G. Williams, Jennifer M. Koh, Erin M. Humphries, Daniel Bucio-Noble, Daniela Lee-Smith, Natasha Lucas, Dylan Xavier, Alexander Menzies, Ines Da Silva, Felicity Newell, Rosemary Balleine, Peter G. Hains, Graham Mann, Phil J. Robinson, Georgina V. Long, James Wilmott, Qing Zhong, Richard A. Scolyer, Roger R. Reddel
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5479.
https://doi.org/10.1158/1538-7445.AM2023-5479
Published: 04 April 2023
View article titled, Abstract 5479: A six-protein signature predicts response and survival in patients with advanced cutaneous melanoma treated with immunotherapy
Journal Articles

Abstract 6747: Sites of metastases prior to systemic treatment influence progression patterns and survival in stage IV melanoma patients

Ismael A. Vergara, Serigne N. Lo, Isabel Li, Alexander M. Menzies, Matteo S. Carlino, Richard A. Scolyer, Georgina V. Long, Ines Pires da Silva
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6747.
https://doi.org/10.1158/1538-7445.AM2023-6747
Published: 04 April 2023
View article titled, Abstract 6747: Sites of metastases prior to systemic treatment influence progression patterns and survival in stage IV melanoma patients
Journal Articles

Abstract 2221: Molecular analysis finds excision margin width predictive of recurrence in acral melanoma

Grace Heloise Attrill, Teresa A. Bailey, Trina Lum, Jordan W. Conway, Georgina V. Long, James S. Wilmott, Richard A. Scolyer
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2221.
https://doi.org/10.1158/1538-7445.AM2022-2221
Published: 15 June 2022
View article titled, Abstract 2221: Molecular analysis finds excision margin width predictive of recurrence in acral melanoma
Journal Articles

Abstract CT250: A first-in-human phase 1 study of NL-201 in patients with relapsed or refractory cancer

Aung Naing, Margaret Callahan, Brian A. Costello, Brendan Curti, Evan Hall, Aaron Hansen, Georgina V. Long, Anthony M. Joshua, Cynthia Wetmore, Andrew Weickhardt
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT250.
https://doi.org/10.1158/1538-7445.AM2022-CT250
Published: 15 June 2022
View article titled, Abstract CT250: A first-in-human phase 1 study of NL-201 in patients with relapsed or refractory cancer
Journal Articles

Abstract 2762: Spatial distribution and immune cell infiltration at different sites of melanoma metastases (mets)

Jordan W. Conway, Robert V. Rawson, James S. Wilmott, Georgina V. Long, Richard A. Scolyer, Inês Pires Da Silva
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2762.
https://doi.org/10.1158/1538-7445.AM2021-2762
Published: 01 July 2021
View article titled, Abstract 2762: Spatial distribution and immune cell infiltration at different sites of melanoma metastases (mets)
Journal Articles

Abstract CT004: Adjuvant therapy with nivolumab (NIVO) combined with ipilimumab (IPI) vs NIVO alone in patients (pts) with resected stage IIIB-D/IV melanoma (CheckMate 915)

Georgina V. Long, Dirk Schadendorf, Michele Del Vecchio, James Larkin, Victoria Atkinson, Michael Schenker, Jacopo Pigozzo, Helen J. Gogas, Stéphane Dalle, Nicolas Meyer, Paolo A. Ascierto, Shahneen Sandhu, Thomas Eigentler, Ralf Gutzmer, Jessica C. Hassel, Caroline Robert, Matteo Carlino, Anna Maria Di Giacomo, Marcus O. Butler, Eva Muñoz-Couselo, Michael P. Brown, Piotr Rutkowski, Andrew Haydon, Jean-Jacques Grob, Jacob Schachter, Paola Queirolo, Alexander Menzies, Sandra Re, Tuba O. Bas, Veerle de Pril, Daniel Tenney, Hao Tang, Jeffrey S. Weber
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): CT004.
https://doi.org/10.1158/1538-7445.AM2021-CT004
Published: 01 July 2021
View article titled, Abstract CT004: Adjuvant therapy with nivolumab (NIVO) combined with ipilimumab (IPI) vs NIVO alone in patients (pts) with resected stage IIIB-D/IV melanoma (CheckMate 915)
Journal Articles

Abstract 2761: CODEX highly multiplex image mapping to CITEseq datasets reveal the spatial dynamics of the TME during the development of acquired resistant in immunotherapy treated melanoma

Camelia Quek, Ines P. Silva, Ghamdan Al-Eryani, Aaron Mayer, Nenad Bartonicek, Kate Harvey, Chi Buckley, Oliver Braubach, John F. Thompson, Jonathan R. Stretch, Robyn P M Saw, Kerwin F. Shannon, Alexander M. Menzies, Richard A. Scolyer, Georgina V. Long, Alexander Swarbrick, James S. Wilmott
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2761.
https://doi.org/10.1158/1538-7445.AM2021-2761
Published: 01 July 2021
View article titled, Abstract 2761: CODEX highly multiplex image mapping to CITEseq datasets reveal the spatial dynamics of the TME during the development of acquired resistant in immunotherapy treated melanoma
Journal Articles

Abstract 2009: Evaluation of RNA-sequencing signatures with response to pembrolizumab (pembro) monotherapy in ipilimumab-naive patients (pts) with melanoma

Adil Daud, Matteo S. Carlino, Antoni Ribas, Ana Arance, Jean-Jacques Grob, James Larkin, Georgina V. Long, Jacob Schachter, Andrea L. Webber, Clemens Krepler, Chunsheng Zhang, Jared Lunceford, Razvan Cristescu, Qing Zhao, Junshui Ma, Caroline Robert
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2009.
https://doi.org/10.1158/1538-7445.AM2020-2009
Published: 15 August 2020
View article titled, Abstract 2009: Evaluation of RNA-sequencing signatures with response to pembrolizumab (pembro) monotherapy in ipilimumab-naive patients (pts) with melanoma
Journal Articles

Abstract 3271: Different pathologic response rates between Australia and Europe in macroscopic stage III melanoma patients upon neoadjuvant ipilimumab plus nivolumab in the phase II OpACIN-neo trial

Irene L. Reijers, Elisa A. Rozeman, Alexander M. Menzies, Judith M. Versluis, Bart A. van de Wiel, Karolina Sikorska, Hanna Eriksson, Kerwin Shannon, Carolien Bierman, Harm van Tinteren, Maria Gonzalez, Andrew J. Spillane, Robyn P. Saw, Alexander C. van Akkooi, Richard A. Scolyer, Johan Hansson, Georgina V. Long, Christian U. Blank
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3271.
https://doi.org/10.1158/1538-7445.AM2020-3271
Published: 15 August 2020
View article titled, Abstract 3271: Different pathologic response rates between Australia and Europe in macroscopic stage III melanoma patients upon neoadjuvant ipilimumab plus nivolumab in the phase II OpACIN-neo trial
Journal Articles

Abstract 3412: 36-months and 18-months relapse-free survival after (neo)adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma patients - update of the OpACIN and OpACIN-neo trials

Christian U. Blank, Judith M. Versluis, Elisa A. Rozeman, Alexander M. Menzies, Irene L. Reijers, Oscar Krijgsman, Esmée P. Hoefsmit, Bart A. van de Wiel, Karolina Sikorska, Carolien Bierman, Petros Dimitriadis, Maria Gonzalez, Annegien Broeks, Ron M. Kerkhoven, Andrew J. Spillane, John B. Haanen, Winan J. van Houdt, Robyn P. Saw, Hanna Eriksson, Alexander C. van Akkooi, Richard A. Scolyer, Ton N. Schumacher, Georgina V. Long
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3412.
https://doi.org/10.1158/1538-7445.AM2020-3412
Published: 15 August 2020
View article titled, Abstract 3412: 36-months and 18-months relapse-free survival after (neo)adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma patients - update of the OpACIN and OpACIN-neo trials