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Journal Articles

Abstract 6461: The spatial cellular landscape of Gleason pattern 3 and 4 prostate tumors

Free
Çiğdem Ak, Zeynep Sayar, Guillaume Thibault, M.J. Kuykendall, George Thomas, Vasilis Stavrinides, Young Hwan Chang, Ece S. Eksi
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 6461.
https://doi.org/10.1158/1538-7445.AM2025-6461
Published: 21 April 2025
View articletitled, Abstract 6461: The spatial cellular landscape of Gleason pattern 3 and 4 prostate tumors
Journal Articles

Abstract 3035: Phase I trial of alpha-lactalbumin vaccine in high-risk operable triple-negative breast cancer

Free
George Thomas Budd, Justin M. Johnson, Emily Rhoades, Halle Moore, Holly Levengood, Megan Kruse, Erin Roesch, Jame Abraham, Brenna Elliott, Elena Haury, Rachel Swartz, Holly Pederson, Zahraa Al Hilli, Vincent Tuohy
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3035.
https://doi.org/10.1158/1538-7445.AM2023-3035
Published: 04 April 2023
View articletitled, Abstract 3035: Phase I trial of alpha-lactalbumin vaccine in high-risk operable triple-negative breast cancer
Journal Articles

Abstract 1301: T cell intrinsic androgen receptor activity regulates response to immunotherapy

Free
Amy E. Moran, Fanny Polesso, Zheng Xia, George Thomas, Julie Graff
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1301.
https://doi.org/10.1158/1538-7445.AM2022-1301
Published: 15 June 2022
View articletitled, Abstract 1301: T cell intrinsic androgen receptor activity regulates response to immunotherapy
Journal Articles

Oncogenic MYC Induces the Impaired Ribosome Biogenesis Checkpoint and Stabilizes p53 Independent of Increased Ribosome Content

Free
Carmen Morcelle, Sandra Menoyo, Francisco D. Morón-Duran, Albert Tauler, Sara C. Kozma, George Thomas, Antonio Gentilella
Journal: Cancer Research
Cancer Res (2019) 79 (17): 4348–4359.
https://doi.org/10.1158/0008-5472.CAN-18-2718
Published: 03 September 2019
View articletitled, Oncogenic MYC Induces the Impaired Ribosome Biogenesis Checkpoint and Stabilizes p53 Independent of Increased Ribosome Content
Open the PDF for Oncogenic MYC Induces the Impaired Ribosome Biogenesis Checkpoint and Stabilizes p53 Independent of Increased Ribosome Content in another window
Includes: Supplementary data
Journal Articles

Abstract B05: Characterization of the pre-ribosomal complex, which mediates the p53 Impaired Ribosome Biogenesis Checkpoint (IRBC)

Free
Sandra Menoyo, Antonio Gentilella, George Thomas
Journal: Cancer Research
Cancer Res (2017) 77 (6_Supplement): B05.
https://doi.org/10.1158/1538-7445.Transcontrol16-B05
Published: 14 March 2017
View articletitled, Abstract B05: Characterization of the pre-ribosomal complex, which mediates the p53 Impaired Ribosome Biogenesis Checkpoint (IRBC)
Journal Articles

Abstract PR02: A novel 40S complex involved in the regulation of 5' TOP mRNA stability: A role in mTOR hyperactivated tumors?

Free
Antonio Gentilella, Francisco D. Morón-Duran, Guilherme Z. Rocha, Ferran Riaño-Canalias, Joffrey Pelletier, Albert Tauler, Sara Kozma, George Thomas
Journal: Cancer Research
Cancer Res (2017) 77 (6_Supplement): PR02.
https://doi.org/10.1158/1538-7445.Transcontrol16-PR02
Published: 14 March 2017
View articletitled, Abstract PR02: A novel 40S complex involved in the regulation of 5' TOP mRNA stability: A role in mTOR hyperactivated tumors?
Journal Articles

Abstract 2024: c-Myc driven B cell lymphomas: role of the RPL5/RPL11/5S rRNA-MDM2 inhibitory complex (L5/L11/5S-MIC)

Free
Suresh Peddigari, Carol Mercer, Sara Kozma, George Thomas
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2024.
https://doi.org/10.1158/1538-7445.AM2015-2024
Published: 01 August 2015
View articletitled, Abstract 2024: c-Myc driven B cell lymphomas: role of the RPL5/RPL11/5S rRNA-MDM2 inhibitory complex (L5/L11/5S-MIC)
Journal Articles

Abstract 731: Integrative genomic analysis to identify emergent enzalutamide resistance mechanisms in castration-resistant prostate cancer

Free
Josha Woodward, Carly King, Daniel Coleman, Robert Lisac, Jacob Schwartzman, Nicholas Wang, Martin Gleave, Joe Gray, George Thomas, Tomasz M. Beer, Katy Van Hook, Robert Baertsch, Ted Goldstein, Josh Stuart, Lina Gao, Joshua Urrutia, Laura Heiser, Joshi J. Alumkal
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 731.
https://doi.org/10.1158/1538-7445.AM2015-731
Published: 01 August 2015
View articletitled, Abstract 731: Integrative genomic analysis to identify emergent enzalutamide resistance mechanisms in castration-resistant prostate cancer
Journal Articles

Abstract 4629: Physiologically based pharmacokinetic model and correlative in vitro assessment of metabolism-based interaction between Everolimus and PI3K/mTOR inhibitor BEZ235

Free
Ganesh P. Moorthy, Bilal Abuasal, Larry Sallans, John C. Morris, George Thomas, Pankaj B. Desai
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4629.
https://doi.org/10.1158/1538-7445.AM2014-4629
Published: 01 October 2014
View articletitled, Abstract 4629: Physiologically based pharmacokinetic model and correlative in vitro assessment of metabolism-based interaction between Everolimus and PI3K/mTOR inhibitor BEZ235
Journal Articles

Animal Models of Human Prostate Cancer: The Consensus Report of the New York Meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee

Free
Michael Ittmann, Jiaoti Huang, Enrico Radaelli, Philip Martin, Sabina Signoretti, Ruth Sullivan, Brian W. Simons, Jerrold M. Ward, Brian D. Robinson, Gerald C. Chu, Massimo Loda, George Thomas, Alexander Borowsky, Robert D. Cardiff
Journal: Cancer Research
Cancer Res (2013) 73 (9): 2718–2736.
https://doi.org/10.1158/0008-5472.CAN-12-4213
Published: 30 April 2013
View articletitled, Animal Models of Human Prostate Cancer: The Consensus Report of the New York Meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee
Open the PDF for Animal Models of Human Prostate Cancer: The Consensus Report of the New York Meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee in another window
Includes: Supplementary data
Journal Articles

Differential Expression of S6K2 Dictates Tissue-Specific Requirement for S6K1 in Mediating Aberrant mTORC1 Signaling and Tumorigenesis

Free
Caterina Nardella, Andrea Lunardi, Giuseppe Fedele, John G. Clohessy, Andrea Alimonti, Sara C. Kozma, George Thomas, Massimo Loda, Pier Paolo Pandolfi
Journal: Cancer Research
Cancer Res (2011) 71 (10): 3669–3675.
https://doi.org/10.1158/0008-5472.CAN-10-3962
Published: 15 May 2011
View articletitled, Differential Expression of S6K2 Dictates Tissue-Specific Requirement for S6K1 in Mediating Aberrant mTORC1 Signaling and Tumorigenesis
Open the PDF for Differential Expression of S6K2 Dictates Tissue-Specific Requirement for S6K1 in Mediating Aberrant mTORC1 Signaling and Tumorigenesis in another window
Includes: Supplementary data
Journal Articles

Abstract 5349: Vesicular stomatitis virus oncolysis is potentiated by impairing mTORC1-dependent type-I IFN production

Free
Tommy Alain, XueQing Lun, Yvan Martineau, Polen Sean, Bali Pulendran, Emmanuel Petroulakis, Franz Zemp, Chantal G. Lemay, Dominic Roy, John C. Bell, George Thomas, Sara C. Kozma, Peter A. Forsyth, Mauro Costa-Mattioli, Nahum Sonenberg
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5349.
https://doi.org/10.1158/1538-7445.AM10-5349
Published: 15 April 2010
View articletitled, Abstract 5349: Vesicular stomatitis virus oncolysis is potentiated by impairing mTORC1-dependent type-I IFN production
Journal Articles

Genetic Background Controls Tumor Development in Pten-Deficient Mice

Free
Dan Freeman, Ralf Lesche, Nathalie Kertesz, Shungyou Wang, Gang Li, Jing Gao, Matthias Groszer, Hilda Martinez-Diaz, Nora Rozengurt, George Thomas, Xin Liu, Hong Wu
Journal: Cancer Research
Cancer Res (2006) 66 (13): 6492–6496.
https://doi.org/10.1158/0008-5472.CAN-05-4143
Published: 03 July 2006
View articletitled, Genetic Background Controls Tumor Development in Pten-Deficient Mice
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Includes: Supplementary data
Journal Articles

Antitumor Efficacy of Intermittent Treatment Schedules with the Rapamycin Derivative RAD001 Correlates with Prolonged Inactivation of Ribosomal Protein S6 Kinase 1 in Peripheral Blood Mononuclear Cells

Free
Anne Boulay, Sabine Zumstein-Mecker, Christine Stephan, Iwan Beuvink, Frederic Zilbermann, Roland Haller, Sonja Tobler, Christoph Heusser, Terence O’Reilly, Barbara Stolz, Andreas Marti, George Thomas, Heidi A. Lane
Journal: Cancer Research
Cancer Res (2004) 64 (1): 252–261.
https://doi.org/10.1158/0008-5472.CAN-3554-2
Published: 16 January 2004
View articletitled, Antitumor Efficacy of Intermittent Treatment Schedules with the Rapamycin Derivative RAD001 Correlates with Prolonged Inactivation of Ribosomal Protein S6 Kinase 1 in Peripheral Blood Mononuclear Cells
Open the PDF for Antitumor Efficacy of Intermittent Treatment Schedules with the Rapamycin Derivative RAD001 Correlates with Prolonged Inactivation of Ribosomal Protein S6 Kinase 1 in Peripheral Blood Mononuclear Cells in another window
Journal Articles

Evaluation of Microsatellite Instability and Immunohistochemistry for the Prediction of Germ-Line MSH2 and MLH1 Mutations in Hereditary Nonpolyposis Colon Cancer Families

Free
Siobhan S. Wahlberg, James Schmeits, George Thomas, Massimo Loda, Judy Garber, Sapna Syngal, Richard D. Kolodner, Edward Fox
Journal: Cancer Research
Cancer Res (2002) 62 (12): 3485–3492.
Published: 01 June 2002
View articletitled, Evaluation of Microsatellite Instability and Immunohistochemistry for the Prediction of Germ-Line MSH2 and MLH1 Mutations in Hereditary Nonpolyposis Colon Cancer Families
Open the PDF for Evaluation of Microsatellite Instability and Immunohistochemistry for the Prediction of Germ-Line MSH2 and MLH1 Mutations in Hereditary Nonpolyposis Colon Cancer Families in another window