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George Sgouros
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Journal Articles

Abstract 213: Assessing the role of X-ray radiation in combination with a DNA-PK inhibitor on cellular activity and adhesion using an in vitro HER2-positive breast cancer model

Mahmud Hasan, Ioanna Liatsou, George Sgouros
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 213.
https://doi.org/10.1158/1538-7445.AM2022-213
Published: 15 June 2022
View articletitled, Abstract 213: Assessing the role of X-ray radiation in combination with a DNA-PK inhibitor on cellular activity and adhesion using an in vitro HER2-positive breast cancer model
Journal Articles

Abstract 3313: Single-cell level absorbed dose assessment and radiosensitivity modeling for alpha-emitter radiopharmaceutical therapy

Remco Bastiaannet, Ioanna Liatsou, Robert Hobbs, George Sgouros
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3313.
https://doi.org/10.1158/1538-7445.AM2022-3313
Published: 15 June 2022
View articletitled, Abstract 3313: Single-cell level absorbed dose assessment and radiosensitivity modeling for alpha-emitter radiopharmaceutical therapy
Journal Articles

Abstract 1395: Humanized GD2 antibody for targeted radiopharmaceutical therapy of human and canine osteosarcoma

Yingli Fu, Jing Yu, Ioanna Liatsou, Anders Josefsson, Yong Du, Jeffrey Bryan, Dara L. Kraitchman, George Sgouros
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1395.
https://doi.org/10.1158/1538-7445.AM2021-1395
Published: 01 July 2021
View articletitled, Abstract 1395: Humanized GD2 antibody for targeted radiopharmaceutical therapy of human and canine osteosarcoma
Journal Articles

Abstract 5350: RBE, in vivo, for a 212Pb-conjugated anti-HER2/neu antibody

Ioanna Liatsou, Anders Josefsson, Angel Cortez, Robert F. Hobbs, Cory Brayton, Julien Torgue, George Sgouros
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5350.
https://doi.org/10.1158/1538-7445.AM2020-5350
Published: 15 August 2020
View articletitled, Abstract 5350: RBE, in vivo, for a 212Pb-conjugated anti-HER2/neu antibody
Journal Articles

Abstract 6281: Differential response of irradiated breast carcinoma cells to DNA-PK inhibition: Spheroid response is governed by cell adhesion effects rather than changes in radiosensitivity

Jing Yu, Ryan Lu, Jessie Nedrow, George Sgouros
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 6281.
https://doi.org/10.1158/1538-7445.AM2020-6281
Published: 15 August 2020
View articletitled, Abstract 6281: Differential response of irradiated breast carcinoma cells to DNA-PK inhibition: Spheroid response is governed by cell adhesion effects rather than changes in radiosensitivity
Journal Articles

Mathematical Modeling of Preclinical Alpha-Emitter Radiopharmaceutical Therapy

Alireza Karimian, Nathan T. Ji, Hong Song, George Sgouros
Journal: Cancer Research
Cancer Res (2020) 80 (4): 868–876.
https://doi.org/10.1158/0008-5472.CAN-19-2553
Published: 14 February 2020
View articletitled, Mathematical Modeling of Preclinical Alpha-Emitter Radiopharmaceutical Therapy
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Includes: Supplementary data
Journal Articles

α-Particle–Emitter Radiopharmaceutical Therapy: Resistance Is Futile

George Sgouros
Journal: Cancer Research
Cancer Res (2019) 79 (21): 5479–5481.
https://doi.org/10.1158/0008-5472.CAN-19-2806
Published: 01 November 2019
View articletitled, α-Particle–Emitter Radiopharmaceutical Therapy: Resistance Is Futile
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Journal Articles

Abstract 863: Targeted α-therapy for treatment of metastatic melanoma

Jessie Nedrow, Greg McCarty, Angel Cortez, Sanchita Roy, George Sgouros
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 863.
https://doi.org/10.1158/1538-7445.AM2018-863
Published: 01 July 2018
View articletitled, Abstract 863: Targeted α-therapy for treatment of metastatic melanoma
Journal Articles

Abstract 3052: Combining α-particle radiopharmaceutical therapy using Actinium-225 and immunotherapy with anti-PD-L1 antibodies in a murine immunocompetent metastatic breast cancer model

Anders Josefsson, Jessie R. Nedrow, Sunju Park, Sagar Ranka, George Sgouros
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3052.
https://doi.org/10.1158/1538-7445.AM2016-3052
Published: 15 July 2016
View articletitled, Abstract 3052: Combining α-particle radiopharmaceutical therapy using Actinium-225 and immunotherapy with anti-PD-L1 antibodies in a murine immunocompetent metastatic breast cancer model
Journal Articles

Abstract 4279: Human HER2-overexpressing mouse breast cancer cell lines derived from MMTV.f.HuHER2 mice: characterization and use in a model of metastatic breast cancer

Sunju Park, George Sgouros
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4279.
https://doi.org/10.1158/1538-7445.AM2016-4279
Published: 15 July 2016
View articletitled, Abstract 4279: Human HER2-overexpressing mouse breast cancer cell lines derived from MMTV.f.HuHER2 mice: characterization and use in a model of metastatic breast cancer
Journal Articles

Abstract LB-183: The impact of protein concentration on the distribution of 111In-antibody conjugate for imaging of programmed death-ligand 1 (PD-L1)

Jessie Nedrow, Anders Josefsson, Sunju Park, Sagar Ranka, George Sgouros
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): LB-183.
https://doi.org/10.1158/1538-7445.AM2016-LB-183
Published: 15 July 2016
View articletitled, Abstract LB-183: The impact of protein concentration on the distribution of 111In-antibody conjugate for imaging of programmed death-ligand 1 (PD-L1)
Journal Articles

Imaging, Biodistribution, and Dosimetry of Radionuclide-Labeled PD-L1 Antibody in an Immunocompetent Mouse Model of Breast Cancer

Anders Josefsson, Jessie R. Nedrow, Sunju Park, Sangeeta Ray Banerjee, Andrew Rittenbach, Fabien Jammes, Benjamin Tsui, George Sgouros
Journal: Cancer Research
Cancer Res (2016) 76 (2): 472–479.
https://doi.org/10.1158/0008-5472.CAN-15-2141
Published: 14 January 2016
View articletitled, Imaging, Biodistribution, and Dosimetry of Radionuclide-Labeled PD-L1 Antibody in an Immunocompetent Mouse Model of Breast Cancer
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Journal Articles

Abstract 4533: Synthesis and biodistribution of 225Ac-substance P for intracavitary radiopharmaceutical therapy of high-grade recurrent glioma.

Hong Song, Hugo Guerrero-Cazares, Andrew Horti, Richard L. Wahl, Alfredo Quinones-Hinojosa, George Sgouros
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4533.
https://doi.org/10.1158/1538-7445.AM2013-4533
Published: 15 April 2013
View articletitled, Abstract 4533: Synthesis and biodistribution of 225Ac-substance P for intracavitary radiopharmaceutical therapy of high-grade recurrent glioma.
Journal Articles

Abstract 5081: Inhibiting DNA double strand break repair for alpha radioimmunotherapy

Hong Song, Robert F. Hobbs, Chunbo Shao, George Sgouros
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 5081.
https://doi.org/10.1158/1538-7445.AM2011-5081
Published: 15 April 2011
View articletitled, Abstract 5081: Inhibiting DNA double strand break repair for alpha radioimmunotherapy
Journal Articles

Immunoliposomal Delivery of 213Bi for α-Emitter Targeting of Metastatic Breast Cancer

Mohanambe Lingappa, Hong Song, Sarah Thompson, Frank Bruchertseifer, Alfred Morgenstern, George Sgouros
Journal: Cancer Research
Cancer Res (2010) 70 (17): 6815–6823.
https://doi.org/10.1158/0008-5472.CAN-09-4548
Published: 31 August 2010
View articletitled, Immunoliposomal Delivery of 213Bi for α-Emitter Targeting of Metastatic Breast Cancer
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Journal Articles

Radioimmunotherapy of Breast Cancer Metastases with α-Particle Emitter 225Ac: Comparing Efficacy with 213Bi and 90Y

Hong Song, Robert F. Hobbs, Ravy Vajravelu, David L. Huso, Caroline Esaias, Christos Apostolidis, Alfred Morgenstern, George Sgouros
Journal: Cancer Research
Cancer Res (2009) 69 (23): 8941–8948.
https://doi.org/10.1158/0008-5472.CAN-09-1828
Published: 30 November 2009
View articletitled, Radioimmunotherapy of Breast Cancer Metastases with α-Particle Emitter 225Ac: Comparing Efficacy with 213Bi and 90Y
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Journal Articles

213Bi (α-Emitter)–Antibody Targeting of Breast Cancer Metastases in the neu-N Transgenic Mouse Model

Hong Song, Karineh Shahverdi, David L. Huso, Caroline Esaias, James Fox, Allison Liedy, Zhe Zhang, R. Todd Reilly, Christos Apostolidis, Alfred Morgenstern, George Sgouros
Journal: Cancer Research
Cancer Res (2008) 68 (10): 3873–3880.
https://doi.org/10.1158/0008-5472.CAN-07-6308
Published: 15 May 2008
View articletitled, 213Bi (α-Emitter)–Antibody Targeting of Breast Cancer Metastases in the neu-N Transgenic Mouse Model
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Journal Articles

Liposomal delivery of radionuclides treating ovarian cancer metastases

Yah-el Har-el, George Sgouros
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5726.
Published: 01 May 2008
View articletitled, Liposomal delivery of radionuclides treating ovarian cancer metastases
Journal Articles

Therapeutic efficacy of alpha-emitter (213Bi) labeled and beta-emitter (90Y) labeled anti-HER-2/neu monoclonal antibody in treating breast cancer metastases to the lungs

Hong Song, Ravy Vajravelu, Caroline Esaias, George Sgouros
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 3169.
Published: 01 May 2008
View articletitled, Therapeutic efficacy of alpha-emitter (213Bi) labeled and beta-emitter (90Y) labeled anti-HER-2/neu monoclonal antibody in treating breast cancer metastases to the lungs
Journal Articles

Alpha-particle emitting monoclonal antibody [213Bi-7.16.4] prolongs survival of HER-2/neu transgenic mice bearing HER-2/neu expressing micrometastases

Hong Song, Karineh Shahverdi, Caroline Esaias, James Fox, Zhe Zhang, R. Reilly, Christos Apostolidis, Alfred Morgenstern, George Sgouros
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4907.
Published: 01 May 2007
View articletitled, Alpha-particle emitting monoclonal antibody [213Bi-7.16.4] prolongs survival of HER-2/neu transgenic mice bearing HER-2/neu expressing micrometastases