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George J. Netto
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Journal Articles

Abstract 6586: Updates to UALCAN, a comprehensive cancer proteogenomic data analysis platform for discovery research

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Darshan Shimoga Chandrashekar, Sooryanarayana Varambally, Santhosh Kumar Karthikeyan, Praveen Kumar Korla, Henalben Patel, Mohammad Athar, Upender Manne, George J. Netto, Ahmedur Rahman Shovon, Sidharth Kumar, Zhaohui S. Qin, Chad J. Crieghton
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6586.
https://doi.org/10.1158/1538-7445.AM2023-6586
Published: 04 April 2023
View articletitled, Abstract 6586: Updates to UALCAN, a comprehensive cancer proteogenomic data analysis platform for discovery research
Journal Articles

Gut Microbiota–Derived Short-Chain Fatty Acids Promote Prostate Cancer Growth via IGF1 Signaling

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Makoto Matsushita, Kazutoshi Fujita, Takuji Hayashi, Hisako Kayama, Daisuke Motooka, Hiroaki Hase, Kentaro Jingushi, Gaku Yamamichi, Satoru Yumiba, Eisuke Tomiyama, Yoko Koh, Yujiro Hayashi, Kosuke Nakano, Cong Wang, Yu Ishizuya, Taigo Kato, Koji Hatano, Atsunari Kawashima, Takeshi Ujike, Motohide Uemura, Ryoichi Imamura, Maria D.C. Rodriguez Pena, Jennifer B. Gordetsky, George J. Netto, Kazutake Tsujikawa, Shota Nakamura, Kiyoshi Takeda, Norio Nonomura
Journal: Cancer Research
Cancer Res (2021) 81 (15): 4014–4026.
https://doi.org/10.1158/0008-5472.CAN-20-4090
Published: 01 August 2021
View articletitled, Gut Microbiota–Derived Short-Chain Fatty Acids Promote Prostate Cancer Growth via IGF1 Signaling
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Includes: Supplementary data
Journal Articles

Abstract 2071: Identification of FOXO1 as a tumor suppressor modulated by androgen receptor/estrogen receptor-βsignals: Implications for bladder cancer promotion and chemoresistance

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Hiroki Ide, Satoshi Inoue, Taichi Mizushima, Guiyang Jiang, Takuro Goto, Yujiro Nagata, Yuki Teramoto, George J. Netto, Mototsugu Oya, Hiroshi Miyamoto
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2071.
https://doi.org/10.1158/1538-7445.AM2020-2071
Published: 15 August 2020
View articletitled, Abstract 2071: Identification of FOXO1 as a tumor suppressor modulated by androgen receptor/estrogen receptor-βsignals: Implications for bladder cancer promotion and chemoresistance
Journal Articles

Abstract 5247: Overexpression of methylenetetrahydrofolate dehydrogenase 1 like (MTHFD1L) in bladder cancer: A potential therapeutic target

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Marie-Lisa Eich, Maria D. Rodriguez Pena, Darshan S. Chandrashekar, Jennifer B. Gordetsky, George J. Netto, Sooryanarayana Varambally
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 5247.
https://doi.org/10.1158/1538-7445.AM2019-5247
Published: 01 July 2019
View articletitled, Abstract 5247: Overexpression of methylenetetrahydrofolate dehydrogenase 1 like (MTHFD1L) in bladder cancer: A potential therapeutic target
Journal Articles

YAP1 and COX2 Coordinately Regulate Urothelial Cancer Stem-like Cells

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Akira Ooki, Maria Del Carmen Rodriguez Pena, Luigi Marchionni, Wikum Dinalankara, Asma Begum, Noah M. Hahn, Christopher J. VandenBussche, Zeshaan A. Rasheed, Shifeng Mao, George J. Netto, David Sidransky, Mohammad O. Hoque
Journal: Cancer Research
Cancer Res (2018) 78 (1): 168–181.
https://doi.org/10.1158/0008-5472.CAN-17-0836
Published: 02 January 2018
View articletitled, YAP1 and COX2 Coordinately Regulate Urothelial Cancer Stem-like Cells
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Includes: Supplementary data
Journal Articles

Abstract 2458: Spatial genomic heterogeneity of multifocal bladder cancer

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Rachel Goldberg, Maria Del Carmen Rodriguez, Leslie Cope, Aline C. Tregnago, Evgeny Izumchenko, George J. Netto, David Sidransky, Mohammad O. Hoque
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2458.
https://doi.org/10.1158/1538-7445.AM2017-2458
Published: 01 July 2017
View articletitled, Abstract 2458: Spatial genomic heterogeneity of multifocal bladder cancer
Journal Articles

Abstract 1551: GULP1 is an epigenetically altered and functional tumor suppressor in urothelial carcinoma through regulation of Nrf2-Keap1 signaling axis

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Masamichi Hayashi, Elisa Guida, Rachel Goldberg, Yoshikuni Inokawa, Leonardo Reis, Akira Oki, Evgeny Izumchenko, Leonel Maldonado, Luigi Marchionni, Mariana Brait, Trinity Bivalacqua, Alexander Baras, George J. Netto, Wayne Koch, David Sidransky, Mohammad O. Hoque
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1551.
https://doi.org/10.1158/1538-7445.AM2017-1551
Published: 01 July 2017
View articletitled, Abstract 1551: GULP1 is an epigenetically altered and functional tumor suppressor in urothelial carcinoma through regulation of Nrf2-Keap1 signaling axis
Journal Articles

Abstract 4466: GULP1 is a potential tumor suppressor that modulates chemo-resistance through regulation of Nrf2-Keap1 signaling axis in urothelial carcinoma

Free
Elisa Guida, Masamichi Hayashi, Alexander Baras, Leonel Maldonado, Mariana Brait, Leonardo Reis, akira oki, Evgeny Izumchenko, trinity bivalaqua, george J. Netto, Wayne Koch, David Sidransky, mohammad O. Hoque
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4466.
https://doi.org/10.1158/1538-7445.AM2016-4466
Published: 15 July 2016
View articletitled, Abstract 4466: GULP1 is a potential tumor suppressor that modulates chemo-resistance through regulation of Nrf2-Keap1 signaling axis in urothelial carcinoma
Journal Articles

Abstract 5035: MDB-seq screening of muscle-invasive urothelial carcinoma revealed unpredicted novel tumor suppressor genes

Free
Elisa Guida, Luigi Marchionni, Rachel Goldberg, Mark Schoenberg, Trinity Bivalaqua, George J. Netto, Mohammad O. Moque, David Sidransky
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 5035.
https://doi.org/10.1158/1538-7445.AM2016-5035
Published: 15 July 2016
View articletitled, Abstract 5035: MDB-seq screening of muscle-invasive urothelial carcinoma revealed unpredicted novel tumor suppressor genes
Journal Articles

Androgen-Regulated SPARCL1 in the Tumor Microenvironment Inhibits Metastatic Progression

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Paula J. Hurley, Robert M. Hughes, Brian W. Simons, Jessie Huang, Rebecca M. Miller, Brian Shinder, Michael C. Haffner, David Esopi, Yasunori Kimura, Javaneh Jabbari, Ashley E. Ross, Nicholas Erho, Ismael A. Vergara, Sheila F. Faraj, Elai Davicioni, George J. Netto, Srinivasan Yegnasubramanian, Steven S. An, Edward M. Schaeffer
Journal: Cancer Research
Cancer Res (2015) 75 (20): 4322–4334.
https://doi.org/10.1158/0008-5472.CAN-15-0024
Published: 14 October 2015
View articletitled, Androgen-Regulated SPARCL1 in the Tumor Microenvironment Inhibits Metastatic Progression
Open the PDF for Androgen-Regulated SPARCL1 in the Tumor Microenvironment Inhibits Metastatic Progression in another window
Includes: Supplementary data
Journal Articles

Abstract 3783: High resolution telomere FISH analysis of testicular germ cell tumors reveals telomere anomalies specific to cancer subtypes and demonstrates telomere shortening as an early event in TGCT carcinogenesis

Free
Mohammed T. Shekhani, John Barber, Christopher M. Heaphy, Leonardo Reis, Gunes Guner, Corinne Joshu, George J. Netto, Alan K. Meeker
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3783.
https://doi.org/10.1158/1538-7445.AM2015-3783
Published: 01 August 2015
View articletitled, Abstract 3783: High resolution telomere FISH analysis of testicular germ cell tumors reveals telomere anomalies specific to cancer subtypes and demonstrates telomere shortening as an early event in TGCT carcinogenesis
Journal Articles

Abstract 4943: Engulfment gene GULP1 is a functional tumor suppressor through influencing TGF-β pathway and is silenced by promoter methylation in urothelial carcinoma

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Masamichi Hayashi, Leonardo O. Reis, Alexander Baras, Leonel Maldonado, Eliza Guida, Evgeny Izumchenko, Mariana Brait, Trinity Bivalacqua, George J. Netto, Wayne Koch, David Sidransky, Mohammad O. Hoque
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4943.
https://doi.org/10.1158/1538-7445.AM2015-4943
Published: 01 August 2015
View articletitled, Abstract 4943: Engulfment gene GULP1 is a functional tumor suppressor through influencing TGF-β pathway and is silenced by promoter methylation in urothelial carcinoma
Journal Articles

TERT Promoter Mutations Occur Early in Urothelial Neoplasia and Are Biomarkers of Early Disease and Disease Recurrence in Urine

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Isaac Kinde, Enrico Munari, Sheila F. Faraj, Ralph H. Hruban, Mark Schoenberg, Trinity Bivalacqua, Mohamad Allaf, Simeon Springer, Yuxuan Wang, Luis A. Diaz, Jr., Kenneth W. Kinzler, Bert Vogelstein, Nickolas Papadopoulos, George J. Netto
Journal: Cancer Research
Cancer Res (2013) 73 (24): 7162–7167.
https://doi.org/10.1158/0008-5472.CAN-13-2498
Published: 16 December 2013
View articletitled, TERT Promoter Mutations Occur Early in Urothelial Neoplasia and Are Biomarkers of Early Disease and Disease Recurrence in Urine
Open the PDF for TERT Promoter Mutations Occur Early in Urothelial Neoplasia and Are Biomarkers of Early Disease and Disease Recurrence in Urine in another window
Includes: Supplementary data
Journal Articles

Abstract 3974: A comprehensive resequence-analysis of 250kb region of 8q24 in Africans

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Charles C. Chung, Ann W. Hsing, Meredith Yeager, Edward Yeboah, Richard Biritwum, Yao Tettey, Andrew Adjei, Angelo De Marzo, George J. Netto, William B. Isaacs, Sarah D. Isaacs, Joseph Boland, Stephen J. Chanock
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3974.
https://doi.org/10.1158/1538-7445.AM2012-3974
Published: 15 April 2012
View articletitled, Abstract 3974: A comprehensive resequence-analysis of 250kb region of 8q24 in Africans
Journal Articles

An EGFR-ERK-SOX9 Signaling Cascade Links Urothelial Development and Regeneration to Cancer

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Shizhang Ling, Xiaofei Chang, Luciana Schultz, Thomas K. Lee, Alcides Chaux, Luigi Marchionni, George J. Netto, David Sidransky, David M. Berman
Journal: Cancer Research
Cancer Res (2011) 71 (11): 3812–3821.
https://doi.org/10.1158/0008-5472.CAN-10-3072
Published: 31 May 2011
View articletitled, An EGFR-ERK-SOX9 Signaling Cascade Links Urothelial Development and Regeneration to Cancer
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Includes: Supplementary data
Journal Articles

Abstract 4939: Testicular Germ Cell Tumors: Could Aberrant Promoter Methylation differentiate Seminomas from Non-Seminomas

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Mariana Brait, Leonel Maldonado, Shahnaz Begum, Myriam Loyo, Danielle Wehle, Fabio F. Tavora, Cynthia Lebron, Jeanne Kowalski, Zhe Zhang, George J. Netto, David Sidransky, Mohammad O. Hoque
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4939.
https://doi.org/10.1158/1538-7445.AM10-4939
Published: 15 April 2010
View articletitled, Abstract 4939: Testicular Germ Cell Tumors: Could Aberrant Promoter Methylation differentiate Seminomas from Non-Seminomas
Journal Articles

Cyclophosphamide Augments Antitumor Immunity: Studies in an Autochthonous Prostate Cancer Model

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Satoshi Wada, Kiyoshi Yoshimura, Edward L. Hipkiss, Tim J. Harris, Hung-Rong Yen, Monica V. Goldberg, Joseph F. Grosso, Derese Getnet, Angelo M. Demarzo, George J. Netto, Robert Anders, Drew M. Pardoll, Charles G. Drake
Journal: Cancer Research
Cancer Res (2009) 69 (10): 4309–4318.
https://doi.org/10.1158/0008-5472.CAN-08-4102
Published: 15 May 2009
View articletitled, Cyclophosphamide Augments Antitumor Immunity: Studies in an Autochthonous Prostate Cancer Model
Open the PDF for Cyclophosphamide Augments Antitumor Immunity: Studies in an Autochthonous Prostate Cancer Model in another window
Includes: Supplementary data